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  • Abstract Number: 2321 • 2018 ACR/ARHP Annual Meeting

    Dickkopf-1 Serum Levels in Patients with Systemic Sclerosis and Correlation with Trabecular Bone Score

    Barbara Ruaro1, Andrea Casabella2, Sabrina Paolino1, Carmen Pizzorni2, Vanessa Smith3, Chiara Seriolo4, Luigi Molfetta4, Patrizio Odetti4 and Maurizio Cutolo2, 1Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy, 2Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, 3Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 4Centro di Ricerca su Osteoporosi e Patologie Osteoarticolari CROPO, Di.M.I., Genoa, Italy, Genoa, Italy

    Background/Purpose: Dickkopf-1 (DKK1) is a natural inhibitor of Wnt signaling pathway that could be involved in promoting osteoclastogenesis through suppression of osteoprotegerin (1,2). Systemic sclerosis…
  • Abstract Number: 2322 • 2018 ACR/ARHP Annual Meeting

    Intervals of Bone Mineral Density Measurement during Treatment for Osteoporosis in Patients with Rheumatoid Arthritis

    Seung Yun Lee1, Seong Ryul Kwon1, Mie Jin Lim2, Kyong-Hee Jung3 and Won Park4, 1Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), 2Division of Rheumatology, Departments of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), 3Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South), 4Medicine/Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South)

    Background/Purpose: There is controversy about the intervals of retesting bone mineral density (BMD) in patients treated for osteoporosis. The objective of this study is to…
  • Abstract Number: 2323 • 2018 ACR/ARHP Annual Meeting

    Predictors of Mortality in Patients with Hip Fragility Fracture

    Miguel Guerra1, Sara Ganhão2,3, Francisca Aguiar2,3, Georgina Terroso2, Romana Vieira1, Diana Gonçalves4, Tiago Meirinhos5, Teresa Martins-Rocha2,3, Ana Águeda3,5, Raquel Ferreira2,3, Miguel Bernardes2,3, Carlos Vaz2,3, Raquel Lucas6 and Lúcia Costa2, 1Rheumatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal, 2Rheumatology, Centro Hospitalar de São João, Oporto, Portugal, 3Faculty of Medicine, Oporto University, Oporto, Portugal, 4Rheumatology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal, 5Rheumatology, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, 6Public Health Institute of Oporto University, Oporto, Portugal

    Background/Purpose: In Osteoporosis, hip fractures account for significant disease burden, with increased morbi-mortality and financial load on the patient and healthcare system. This study aimed…
  • Abstract Number: 2324 • 2018 ACR/ARHP Annual Meeting

    Predictors of Refracture in Patients with Hip Fragility Fracture

    Sara Ganhão1,2, Miguel Guerra3, Francisca Aguiar1,2, Georgina Terroso1, Romana Vieira3, Diana Gonçalves4, Teresa Martins-Rocha2,5, Raquel Ferreira1,2, Ana Águeda2,6, Tiago Meirinhos7, Eva Mariz1,2, Raquel Lucas8, Miguel Bernardes1,2, Carlos Vaz1,2 and Lúcia Costa1, 1Rheumatology, Centro Hospitalar de São João, Oporto, Portugal, 2Faculty of Medicine, Oporto University, Oporto, Portugal, 3Rheumatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal, 4Rheumatology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal, 5Rheumatology Department, Centro Hospitalar de São João, Porto, Portugal, Oporto, Portugal, 6Rheumatology, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, 7Serviço de Reumatologia, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, Aveiro, Portugal, 8Public Health, Centro Hospitalar de São João, Oporto, Portugal

    Background/Purpose: Hip fractures are associated with substantially elevated morbidity and mortality and thus represent a serious public health problem. The purpose of this study is…
  • Abstract Number: 2325 • 2018 ACR/ARHP Annual Meeting

    Sex Differences in the Association of Frailty and Bone Mineral Density in Patients with Rheumatoid Arthritis

    Katherine D. Wysham1, Dolores M. Shoback2, John B. Imboden Jr.3 and Patricia Katz4, 1University of California, San Francisco, San Francisco, CA, 2Medicine, San Francisco VA Medical Center, University of California, San Francisco, San Francisco, CA, 3Medicine, University of California, San Francisco, San Francisco, CA, 4University of California San Francisco, San Francisco, CA

    Background/Purpose: Frailty in the general population is associated with poor outcomes including osteoporosis (OP), fracture and death. Frailty occurs at a higher rate in RA…
  • Abstract Number: 2326 • 2018 ACR/ARHP Annual Meeting

    Outcomes One Year after Hip Fracture Repair in the Elderly: Does Social Isolation Matter?

    Lisa A. Mandl1, Serena Lian1, Jackie Szymonifka2, Kirsten Grueter3, Aidan Hadad3 and Joseph Lane3, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Orthopaedic Surgery, Hospital for Special Surgery, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over age 65. Social isolation—how integrated a patient…
  • Abstract Number: 2327 • 2018 ACR/ARHP Annual Meeting

    To Screen or Not to Screen?Dexa Ordering Patterns in SLE Patients Who Take Systemic Glucocorticoids

    Sara Baig1, Smarika Sapkota2, Anna K. Shmagel3, Parastoo Fazeli4, Jeremiah Menk1 and Ann Marie O'Connell5, 1University of Minnesota, Minneapolis, MN, 2Division of General Internal Medicine, University of Minnesota, Minneapolis, MN, 3Rheumatic & Autoimmune Diseases, University of Minnesota, Minneapolis, MN, 4Rheumatology, University of Minnesota, Minneapolis, MN, 5University of Minnesota, MInneapolis, MN

    Background/Purpose: High doses of glucocorticoids (GC) are often used in the treatment of Systemic Lupus Erythematous (SLE), however, studies suggest that SLE patients do not…
  • Abstract Number: 2328 • 2018 ACR/ARHP Annual Meeting

    Current Factors Associated with Insufficient Vitamin D Status in Patients with Osteoporosis

    Sandeep Dhillon1, Arzoo Alam2, Matthew Wong-Pack3, Arthur Lau4, Karen A. Beattie5 and Jonathan D. Adachi6,7, 1Department of Medicine, McMaster University, Hamilton, ON, Canada, 2McMaster University, Hamilton, ON, Canada, 3University of Toronto, Toronto, ON, Canada, 450 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 5Medicine, McMaster University, Hamilton, ON, Canada, 6Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 7St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: In 2010, the Canadian Osteoporosis guidelines recommended that patients with osteoporosis be supplemented with vitamin D and to achieve serum levels ≥75nmol/L. Past studies,…
  • Abstract Number: 2329 • 2018 ACR/ARHP Annual Meeting

    Carotid Atherosclerosis Is Associated with Compromised Volumetric Bone Mineral Density and Microarchitecture in Patients with Inflammatory Arthritis

    Isaac T. Cheng1, Qing Shang2, Edmund Kwok Ming Li2, Priscilla Wong1, Emily WL Kun3, Martin Li4, Tena K. Li1, Tracy Y. Zhu5, PW Alex Lee2, Ling Qin6 and Lai-Shan Tam4, 1Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, Hong Kong, China, 2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 3Department of Medicine, Tai Po Hospital, Hong Kong, Hong Kong, 4Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 5Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, 6Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: Inflammatory arthritis patients had increased risk of atherosclerosis and osteoporosis. The association between presence of carotid plaque and volumetric BMD (vBMD)/microarchitecture is yet to…
  • Abstract Number: 2330 • 2018 ACR/ARHP Annual Meeting

    Vitamin D and Bisphosphonate Therapy in SLE Patients Who Receive Glucocorticoids: Are We Offering the Best Care?

    Smarika Sapkota1, Sara Baig2, Toy Hess3, Ann Marie O'Connell4, Jeremiah Menk3, Parastoo Fazeli5 and Anna K. Shmagel6, 1Division of General Internal Medicine, University of Minnesota, Minneapolis, MN, 2Department of Internal Medicine, University of Minnesota, Minneapolis, MN, 3University of Minnesota, Minneapolis, MN, 4University of Minnesota, Minnepolis, MN, 5Rheumatology, University of Minnesota, Minneapolis, MN, 6Rheumatic & Autoimmune Diseases, University of Minnesota, Minneapolis, MN

    Background/Purpose: Glucocorticoids(GC) are frequently used for the treatment of systemic lupus erythematosus (SLE), and glucocorticoid induced osteoporosis (GIOP) is a well-known complication of long term…
  • Abstract Number: 2331 • 2018 ACR/ARHP Annual Meeting

    Obesity Might Positively Affect TNF Mediated Bone Metabolism in RA Patients

    Mie Jin Lim1, Won Park2, Seong Ryul Kwon3, Kyong-Hee Jung4 and Seung Yun Lee3, 1Division of Rheumatology, Departments of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), 2Medicine/Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South), 3Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), 4Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South)

    Background/Purpose: In this study, we tried to find out the effect of obesity on bone metabolism after one year of anti-TNF agent use. Methods:  Thirty-two…
  • Abstract Number: 2332 • 2018 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Effect´s on Bone Mass and Muscle

    María Lorena Brance1, Bernardo A Pons-Estel2, Javier Quagliatto3, Marisa Jorfen4, Noel Cortese4, Guillermo Berbotto5, Juan Carlos Raggio6, Juan Soldano3, Mariano Palatnik1, Ignacio Chavero1, Carolina Dieguez1, Silvana Di Gregorio7 and Lucas Ricardo Brun8, 1Centro de Reumatología, Rosario, Argentina, 2Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Rosario, Argentina, 3Hospital Provincial, Rosario, Argentina, 4Municipalidad de Rosario, Rosario, Argentina, 5Hospital Escuela Eva Perón, Granadero Baigorria, Argentina, Granadero Baigorria, Argentina, 6Hospital Eva Perón, Granadero Baigorria, Argentina, 7Centre Medic Cetir, Barcelona, Spain, 8School of Medicine. Rosario National University, Bone Biology Laboratory, Rosario, Argentina

    Background/Purpose: Rheumatoid arthritis (RA) is a progressive auto-immune disease characterized by chronic inflammation which leads to joint deformity and disability. However, the bone and muscle…
  • Abstract Number: 2333 • 2018 ACR/ARHP Annual Meeting

    High Serum Uric Acid Protects Against Osteoporosis in Postmenopausal Women: Data from the Korean National Health and Nutrition Examination Survey

    Eun-Jung Park1, In Young Kim2, Jinseok Kim3, Chan Hong Jeon4, Joong Kyong Ahn5, Hoon-Suk Cha2, Eun-Mi Koh2, Hyungjin Kim2 and Jaejoon Lee6, 1Division of Rheumatology, Department of Medicine, National Medical Center, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South), 3Department of Medicine, Jeju National University Hospital, University of Jeju School of Medicine, Jeju, Korea, Republic of (South), 4Division of Rheumatology, Department of Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea, Republic of (South), 5Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South), 6Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South)

    Background/Purpose: Osteoporosis is one of the most common morbidities in postmenopausal women. Although serum uric acid (SUA) accounts for about 50% of extracellular antioxidant activity,…
  • Abstract Number: 2335 • 2018 ACR/ARHP Annual Meeting

    Osteoporotic Fracture Trends in a Population of US Managed Care Enrollees: 2007-2017

    E. Michael Lewiecki1, Benjamin Chastek2, Kevin Sundquist2, Setareh A. Williams3, Deane Leader Jr.3, Richard Weiss3, Yamei Wang3, Lorraine A Fitzpatrick3 and Jeffrey R. Curtis4, 1New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, 2Optum, Eden Prairie, MN, 3Radius Health, Inc., Waltham, MA, 4University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Osteoporosis-related fractures (fractures) are a leading cause of morbidity and disability in the US. Epidemiological data on the occurrence of fractures are limited and…
  • Abstract Number: 2336 • 2018 ACR/ARHP Annual Meeting

    Identification of Osteoporosis As a Reason for Vertebral Fractures in Patients with Rheumatoid Arthritis and Non-Inflammatory Musculoskeletal Diseases – a Comparison between Trabecular Bone Score (TBS) and Bone Mineral Density (BMD)

    Bjoern Buehring1, Xenofon Baraliakos1, Julian Thomas2 and Jürgen Braun1, 1Ruhr-University Bochum, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany

    Identification of osteoporosis as a reason for vertebral fractures in patients with rheumatoid arthritis and non-inflammatory musculoskeletal diseases – A comparison between trabecular bone score…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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