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  • Abstract Number: 1612 • 2017 ACR/ARHP Annual Meeting

    Primary Respiratory Disease in Patients with Systemic Lupus Erythematosus: Data from the Spanish Rheumatology Society Lupus Registry (RELESSER) Cohort

    Javier Narváez1, Helena Borrell2, Fernando Sánchez-Alonso3, Iñigo Rúa-Figueroa4, Francisco Javier López Longo5, María Galindo6, Jaime Calvo-Alén7, Jose Luis Andreu8, Mariano Andres9, Juan José Alegre10, Ricardo Blanco11, Tatiana Cobo-Ibáñez12, Gema Bonilla13, Alina Boteanu14, Elvira Diez Alvarez15, Antonio Fernandez-Nebro16, Mercedes Freire17, Marian Gantes18, Paloma Garcia de la Peña19, Rosario García-Vicuña20, José Hernández Beiraín21, Maria Loreto Horcada22, Jesus Ibañez23, Antonio Juan24, Nuria Lozano-Rivas25, José Luis Marenco de la Fuente26, Rafael-Benito Melero González27, Carlos Alberto Montilla-Morales28, Mireia Moreno29, Alejandro Olivé30, Maria Teresa Oton Sanchez31, Angela Pecondon-Español32, Esther Ruiz Lucea33, Ana Sánchez Atrio34, Gregorio Santos-Soler35, Francisco Toyos36, Esther Uriarte Isacelaya37, Tomas Ramón Vazquez Rodriguez38, Joan Miquel Nolla2 and JM Pego-Reigosa39, 1Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, 2Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 4Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, 5Rheumatology, Hospital Gregorio Marañón, Madrid, Spain, 6Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 7Rheumatology, Hospital de Sierrallana. Torrelavega. Cantabria. Spain, Alava, Spain, 8Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 9RHEUMATOLOGY, Hospital general universitario de Alicante, Alicante, Spain, 10Sección de Reumatología Hospital Universitario Dr Peset Valencia, Valencia, Spain, 11Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 12Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, 13Hospital Universitario La Paz, Madrid, Spain, 14Rheumatology, Hospital Universitario Ramon y Cajal, Madrid, Spain, 15Complejo Asistencial Universitario de León. León. Spain, León, Spain, 16Rheumatology, Regional Universitary Hospital of Málaga, Malaga, Spain, 17Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo HospitalarioUniversitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 18Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, 19Rheumatology, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 20Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 21Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, 22Rheumatology, Hospital de Navarra, Pamplona, Spain, 23Rheumatology, Hospital Povisa, Vigo, Spain, 24Rheumatology, Hospital Son LLatzer, Palma de Mallorca, Spain, 25Rheumatology, Hospital Virgen de la Arrixaca, murcia, Spain, 26Rheumatology, Hospital de Valme, Seville, Spain, 27Rheumatology, EOXI Vigo, Vigo, Spain, 28Hospital Clínico Universitario de Salamanca, Salamanca, Spain, 29Rheumatology, Parc Tauli Hospital Universitari, Sabadell, Spain, 30Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 31Rheumatology Department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain, 32Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, 33Rheumatology, Hospital de Basurto, Bilbao, Spain, 34University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology Department, Alcalá de Henares, Madrid, Spain, 35Rheumatology, Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 36Rheumatology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain, 37Rheumatology, Hospital Universitario de Donosti, San Sebastian, Spain, 38Rheumatology, Hospital Universitario Lucus Augusti, Lugo, Spain, 39Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain

    Background/Purpose: To assess the prevalence, risk factors and impact on mortality of primary respiratory disease in a large retrospective cohort. Methods: All adult patients in…
  • Abstract Number: 1613 • 2017 ACR/ARHP Annual Meeting

    Natural History of Disease Activity and Damage in Patients with Cutaneous Lupus Erythematosus on Standard of Care Treatments Using Longitudinal Registries from Two Academic Dermatology Centers

    Noelle M. Teske1, Khor Jia Ker2,3, Rui Feng4, Benjamin F. Chong1 and Victoria P Werth5, 1Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 2Dermatology, National Skin Centre, Singapore, Singapore, 3Dermatology, University of Pennsylvania, Philadelphia, PA, 4Department of Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania, Philadelphia, PA, 5University of Pennsylvania and the VA Medical Center, Philadelphia, PA

    Background/Purpose: The natural disease course of patients with cutaneous lupus erythematosus (CLE) on standard-of-care treatments is not fully characterized. We sought to characterize their disease…
  • Abstract Number: 1614 • 2017 ACR/ARHP Annual Meeting

    “Do You Know What I Mean?” a Tool to Understand What Lupus Patients Comprehend

    Alexa Meara1, Alexa Meara1, Juliette Yedimenko2, Juliette Yedimenko3, Holly Steigelman2, Stacy P. Ardoin4 and Ellen Peters5, 1Internal Medicine/Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 2The Ohio State University Wexner Medical Center, Columbus, OH, 3The Ohio State University, Columbus, OH, 4Pediatric & Adult Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 5Decision Research, Eugene, OR

    Background/Purpose: Long-term SLE treatment is often complex due to changing clinical manifestations, disease fluctuation, and frequent medication changes. Treatment can be daunting especially to the…
  • Abstract Number: 1615 • 2017 ACR/ARHP Annual Meeting

    Assessment of a Cognitive Impairment Measure in Systemic Lupus Erythematosus

    Nicole Davidson1, Alexa Meara2, Holly Steigelman3, Songzhu Zhao4, Guy Brock5, Wael Jarjour6, Brad H. Rovin7, Samir parikh4, Hareth M. Madhoun8, Lee Hebert9, Isabelle Ayoub4 and Stacy P. Ardoin10, 1The Ohio State University, The Ohio State University, Columbus, OH, 2Internal Medicine/Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 3The Ohio State University Wexner Medical Center, Columbus, OH, 4The Ohio State University, Columbus, OH, 5Department of Biomedical Informatics and Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH, 6Department of Rheumatology/Medicine, Ohio State University, Columbus, OH, 7Ohio State University Medical Center, Columbus, OH, 8Rheumatology/Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, 9Medicine, Ohio State University Medical Center, Columbus, OH, 10Pediatric & Adult Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH

    Background/Purpose: : Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease which can impact the central nervous system in multiple ways, including development of cognitive…
  • Abstract Number: 1616 • 2017 ACR/ARHP Annual Meeting

    Early and Late Onset Biopsy Proven Lupus Nephritis without Other Associated Autoimmune Diseases: Severity and Long-Term Outcome

    Michelle Lopes1, Laryssa Santos2, Luciana Seguro3 and Eloisa Bonfa4, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, São Paulo, Brazil, 3Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Lupus nephritis (LN) usually develops within the first years of Systemic Lupus Erythematosus (SLE) onset and rarely after that. There are scarce studies comparing…
  • Abstract Number: 1617 • 2017 ACR/ARHP Annual Meeting

    Autoimmune Diseases in Patients with Cutaneous Lupus Erythematosus

    Elaine Kunzler1,2, Linda S. Hynan3 and Benjamin F. Chong1, 1Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 2Northeast Ohio Medical University, Rootstown, OH, 3Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX

    Background/Purpose: Increased rates of co-existing autoimmune diseases in the systemic lupus erythematosus (SLE) population have been reported.1 Little is known about the prevalence of autoimmune…
  • Abstract Number: 1618 • 2017 ACR/ARHP Annual Meeting

    Risk Factors for Development of Early Infectious and Non-Infectious Complications in Systemic Lupus Erythematosus Patients Undergoing Major Surgery

    Lauro Quintanilla-González1, Gonzalo Torres-Villalobos2 and Andrea Hinojosa-Azaola3, 1Immunology & Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Departmen of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 3Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with increased cardiovascular and infectious complications due to subclinical atherosclerosis, disease activity and treatment-related factors. The…
  • Abstract Number: 1619 • 2017 ACR/ARHP Annual Meeting

    The Impact of Disease Characteristics on Habitual Physical Activity and Sedentary Behavior Among Patients with Systemic Lupus Erythematosus (SLE)

    Alexandra Legge1, Chris Blanchard1 and John G. Hanly2, 1Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, 2Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) are at increased risk for atherosclerotic cardiovascular disease (ASCVD). As sedentary behavior and lack of physical activity are…
  • Abstract Number: 1620 • 2017 ACR/ARHP Annual Meeting

    Habitual Physical Activity, Sedentary Behavior and Cardiovascular Disease Risk Burden in Systemic Lupus Erythematosus (SLE)

    Alexandra Legge1, Chris Blanchard1 and John G. Hanly2, 1Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, 2Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada

    Background/Purpose: Patients with SLE are at increased risk for atherosclerotic cardiovascular disease (ASCVD). As sedentary behavior and lack of physical activity (PA) have been identified…
  • Abstract Number: 1621 • 2017 ACR/ARHP Annual Meeting

    Prevalence of Cognitive Impairment in Systemic Lupus Erythematosus Assessed By the Automated Neuropsychological Assessment Metrics

    Zahi Touma1, Robin Green2, Lesley Ruttan3, Sabrina Lombardi3, Carmela Tartaglia4, Nicole Anderson5, Jiandong Su6, Kenneth Colosimo6, Michelle Vitti6, Dennisse Bonilla6, Joan E. Wither5, Marvin J. Fritzler7 and Dorcas Beaton8, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, 3Toronto Rehabilitation Institute, Toronto, ON, Canada, 4University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, 5Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 6University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 7Medicine, University of Calgary, Calgary, AB, Canada, 8Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada

    Background/Purpose: The screening and diagnosis of Cognitive Impairment (CI) in Systemic Lupus Erythematosus (SLE) patients is often delayed. CI diagnosed according to the American College…
  • Abstract Number: 1622 • 2017 ACR/ARHP Annual Meeting

    Associations Among Classification Criteria Items within Systemic Lupus Erythematosus

    Zahi Touma1, Ricard Cervera2, Ralph Brinks3, Chiara Tani4, Bimba F. Hoyer5, Karen H. Costenbader6, Valentina Lorenzoni7, Gian Sebastiani8, Sandra V. Navarra9, Eloisa Bonfa10, Rosalind Ramsey-Goldman11, Sara K. Tedeschi12, Thomas Doerner13, Sindhu Johnson14, Martin Aringer15 and Marta Mosca16, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain, 3Hiller Center for Research in Rheumatology, Dusseldorf, Germany, 4University of Pisa, Pisa, Italy, 5Charité University Medicine, Department of Medicine/Rheumatology and Clinical Immunology and German Rheumatism Research Centre Berlin (DRFZ), Berlin, Germany, 6Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 7Sant Anna Scuola Universitaria Superiore Pisa, Pisa, Italy, 8Ospedale San Camillo, Rome, Italy, 9Rheumatology, University of Santo Tomas Hospital, Manila, Philippines, 10Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 11FSM, Northwestern University, Chicago, IL, 12Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 13Charité Universitätmedizin Berlin and DRFZ, Berlin, Germany, 14Division of Rheumatology, University of Toronto, Toronto Scleroderma Program, Sinai Health Systems and University Health Network, Toronto, ON, Canada, 15Medicine III, University Medical Center and Faculty of Medicine at the TU Dresden, Dresden, Germany, 16Rheumatology Unit, University of Pisa, Pisa, Italy

    Background/Purpose: An EULAR/ACR –sponsored project is currently developing new weighted SLE classification criteria including laboratory/clinical items. Combinations of symptoms appear commonly in SLE arguing against…
  • Abstract Number: 1623 • 2017 ACR/ARHP Annual Meeting

    Prevalence of Cognitive Impairment in Systemic Lupus Erythematosus Assessed By a Comprehensive Neuropsychological Battery

    Zahi Touma1, Robin Green2, Carmela Tartaglia3, Lesley Ruttan4, Sabrina Lombardi4, Nicole Anderson5, Jiandong Su6, Kenneth Colosimo6, Michelle Vitti6, Dennisse Bonilla6, Joan E. Wither5, Marvin J. Fritzler7 and Dorcas Beaton8, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, 3University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, 4Toronto Rehabilitation Institute, Toronto, ON, Canada, 5Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 6University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 7Medicine, University of Calgary, Calgary, AB, Canada, 8Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada

     Background/Purpose: Cognitive impairment (CI) is a common neurobehavioural manifestation of SLE. In our recent systematic review, the prevalence of CI was 38% (95% CI: 33-43%)…
  • Abstract Number: 1624 • 2017 ACR/ARHP Annual Meeting

    SLE Disease Activity Index Glucocorticosteroid Index (SLEDAI-2KG) Identifies More Responders Than Sledai-2K

    Zahi Touma1, Dafna D Gladman2, Jiandong Su3, Nicole Anderson4 and Murray Urowitz4, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

     Background/Purpose: Systemic Lupus Erythematosus Disease Activity Index-2000 (SLEDAI-2K) is one of the most commonly used disease activity indices in clinical practice and research but this…
  • Abstract Number: 1625 • 2017 ACR/ARHP Annual Meeting

    Incidence and Outcomes of Venous Thromboembolism in Hospitalized Patients with Systemic Lupus Erythematosus: Results from Nationwide Inpatient Sample Database 2003-2011

    Shweta Kishore1, Varun Mittal2, Shradha Ahuja3 and Vikas Majithia1,4, 1Division of Rheumatology, University of Mississippi, Jackson, MS, 2Division of Hematology and Oncology, Albert Einstein Healthcare Network, Philadelphia, PA, 3Division of Hospital Medicine, University of Mississippi, Jackson, MS, 4Jackson VA Medical Center and University of Mississippi, Jackson, MS

    Background/Purpose: Venous thromboembolism (VTE) is a major cause of mortality and morbidity in hospitalized patients. Hospitalized patients with autoimmune disorders are particularly at risk of…
  • Abstract Number: 1626 • 2017 ACR/ARHP Annual Meeting

    Childhood-Onset Predicts Increased Steroid-Related Damage Among Adults with Systemic Lupus Erythematosus

    Merav Heshin-Bekenstein1, Emily von Scheven2, Aimee O. Hersh3, Laura Trupin4, Edward H. Yelin4 and Erica Lawson1, 1Pediatric Rheumatology, University of California San Francisco, San Francisco, CA, 2Division of Rheumatology, Department of Pediatrics, University of California San Francisco, San Francisco, CA, 3Pediatrics/Rheumatology, University of Utah, Salt Lake City, UT, 4Medicine/Rheumatology, University of California San Francisco, San Francisco, CA

    Background/Purpose: Childhood-onset SLE (cSLE) often presents with severe disease, managed with high-dose steroids. However, little is known about differences in long-term steroid toxicity between adults…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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