Abstracts Archive - Page 1296 of 2607 - ACR Meeting Abstracts

Abstract Number: 1645 • 2018 ACR/ARHP Annual Meeting
Clinical Features of Axial Spondyloarthritis Patients Diagnosed in Secondary Versus a Tertiary Hospital
Ann-Sophie De Craemer^1,2, Thomas Renson^1,2, Philippe Carron^1,2, Peggy Jacques^1,2, Rik Joos^1,3,4, Jan Lenaerts^5,6, Lieve Gyselbrecht⁷, Filip van Den Bosch^1,2 and Dirk Elewaut^1,2, ¹Department of Rheumatology, Ghent University Hospital, Ghent, 9000, Belgium, ²VIB Inflammation Research Center, Ghent, 9000, Belgium, ³Department of Rheumatology, Antwerp University Hospital, Edegem, 2650, Belgium, ⁴Department of Rheumatology, ZNA Jan Palfijn, Merksen, 2170, Belgium, ⁵Reuma Institute Hasselt, Hasselt, 3500, Belgium, ⁶Department of Rheumatology, Leuven University Hospital, Leuven, 3000, Belgium, ⁷Department of Rheumatology, ASZ Aalst, Aalst, 9300, Belgium
Background/Purpose: Diagnosis of axial spondyloarthritis (axSpA) often relies on a positive MRI of the SI joints. However, pitfalls in interpretation of MRI images were recently…
Abstract Number: 1646 • 2018 ACR/ARHP Annual Meeting
Prevalence of Spondyloarthritis in Patients with Anterior Uveitis
Kristyna Bubova^1,2, Monika Gregová^1,2, Katerina Zegzulkova^1,2, Karel Pavelka^1,2, Jarmila Heissigerova^3,4 and Ladislav Šenolt^2,5, ¹Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, ³Department of Ophthalmology, First Faculty of Medicine, Charles University, Prague Czech Republic, Prague, Czech Republic, ⁴Department of Ophthalmology, General University Hospital in Prague, Prague, Czech Republic, Prague, Czech Republic, ⁵First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Anterior uveitis (AU) is a common extraarticular manifestation in spondyloarthritis (SpA). The disease can precede the typical axial and peripheral features. Additionally, some studies…
Abstract Number: 1647 • 2018 ACR/ARHP Annual Meeting
Uveitis, the Most Faithful Partner of Axial Spondyloarthritis
Dafne Capelusnik¹, Malena Cavalieri², Roger Rolon Campuzano³, Maria Celeste Orozco⁴, Natalia Zamora⁵, Emilce E Schneeberger⁶ and Gustavo Citera⁷, ¹Reumatology, Instituto de Rehabilitación Psicofísica, Argentina, CABA, Argentina, ²Reumatologia, Instituto de Rehabilitación Psicofísica, CABA, Argentina, ³Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, ⁴Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁵Reumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, ⁶Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁷Rheumatology Section, Instituto de Rehabilitación Psicofísica, CABA, Argentina
Background/Purpose: Acute Anterior Uveitis (AAU) is the most frequent extra-articular manifestation in axial Spondyloarthritis (axSpA), with an overall prevalence of 32.7%. It is a manifestation…
Abstract Number: 1648 • 2018 ACR/ARHP Annual Meeting
Smoking Status in Patients with Psoriasis and Psoriatic Arthritis: An Irish Perspective
Conor Magee¹, Oliver FitzGerald², Flora Farkas¹, Natsumi Ikumi¹, Phil Gallagher³, Agnes Szentpetery⁴ and Brian Kirby⁵, ¹Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ²Department of Rheumatology, St Vincent's University Hospital and Conway Institute, University College Dublin, Ireland, Dublin, Ireland, ³St. Vincent's University Hospital, Department of Rheumatology, Dublin, Ireland, ⁴Rheumatology, St. Vincent's University Hospital, Dublin 4, Ireland, ⁵Dermatology, St. Vincent's University Hospital, Dublin, Ireland
Background/Purpose: The BIOmarkers of COMorbidities (BIOCOM) in psoriasis study is a longitudinal study which aims to identify clinical, genetic or protein biomarker features associated with…
Abstract Number: 1649 • 2018 ACR/ARHP Annual Meeting
Cohort Identification of Axial Spondyloarthritis in a Large Healthcare Dataset: Current and Future Methods
Gopi Penmetsa¹ and Jessica Walsh², ¹University of Utah, Salt Lake City, UT, ²University of Utah School of Medicine, Salt Lake City, UT, USA, Salt Lake City, UT
Background/Purpose: Big data research is important for studying uncommon diseases in real-world settings. Most big data studies in axial spondyloarthritis (axSpA) have been limited to…
Abstract Number: 1650 • 2018 ACR/ARHP Annual Meeting
Subclinical Atheromatosis and Estimation of Cardiovascular Risk in Patients with Axial Spondyloarthritis
Tomas Cazenave¹, Maria Celeste Orozco², Gustavo Citera³, Emilce E Schneeberger¹ and Marcos G. Rosemffet², ¹Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ³Rheumatology Section, Instituto de Rehabilitación Psicofísica, CABA, Argentina
Background/Purpose: There is evidence that shows an increased cardiovascular risk in patients with Axial Spondyloarthritis (axSpA). Ultrasonography (US) is a simple imaging tool used to…
Abstract Number: 1651 • 2018 ACR/ARHP Annual Meeting
Epidemiology of Depression and Anxiety in Patients with Psoriatic Arthritis: A Systematic Review and Meta-Analysis
Enav Z. Zusman^1,2,3, Alyssa Howren^1,2,3, Jan Dutz⁴ and Mary A. De Vera^1,2,3, ¹Collaboration for Outcomes Research and Evaluation (CORE), Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada, ³Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ⁴Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Shared inflammatory processes underscore a substantial burden and risk of psychiatric complications – namely depression and anxiety – in patients with psoriatic arthritis (PsA),…
Abstract Number: 1652 • 2018 ACR/ARHP Annual Meeting
Musculoskeletal Involvement in Inflammatory Bowel Disease’S Patients: A Mono Centric Experience
Andrea Delle Sedie¹, Linda Ceccarelli², Linda Carli¹, Francesco Costa³, Santino Marchi³ and Marta Mosca¹, ¹Rheumatology Unit, University of Pisa, Pisa, Italy, ²University Gastroenterology Unit, University of Pisa, Pisa, Italy, ³University Gastroenterology Unit, University of Pisa,, Pisa, Italy
Background/Purpose: Musculoskeletal symptoms are frequently reported by patients with inflammatory bowel diseases (IBD). Those symptoms may vary from arthralgia to arthritis, involving peripheral or axial…
Abstract Number: 1653 • 2018 ACR/ARHP Annual Meeting
Psychological Distress in Patients with Axial Spondyloarthritis in Europe. Results from the European Map of Axial Spondyloarthritis Survey
Marco Garrido-Cumbrera^1,2,3, David Galvez-Ruiz^1,3, Laure Gossec⁴, Victoria Navarro-Compán⁵, Denis Poddubnyy^6,7, Souzi Makri⁸, Raj Mahapatra⁹, Pedro Plazuelo-Ramos², Carlos Jesus Delgado Dominguez¹ and Christine Bundy¹⁰, ¹Universidad de Sevilla, Seville, Spain, ²Spanish Coordinator of Spondyloarthritis Associations (CEADE), Madrid, Spain, ³Health & Territory Research (HTR), Seville, Spain, ⁴Sorbonne Universités, Paris, France, ⁵Immuno-Rheumatology research group, IdiPaz. La Paz University Hospital, Madrid, Spain, ⁶Rheumatology, Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷German Rheumatism Research Centre, Berlin, Germany, ⁸Cyprus League Against Rheumatism, Nicosia, Cyprus, ⁹Ankylosing Spondylitis International Federation (ASIF), London, United Kingdom, ¹⁰Cardiff University, Cardiff, United Kingdom
Background/Purpose: To assess the association between sociodemographic characteristics, disease activity, and psychological distress in patients with axSpA. Methods: Between July 2017 and February 2018, 2,846…
Abstract Number: 1654 • 2018 ACR/ARHP Annual Meeting
Improvement of Cytological Grade and Tear Production in Ankylosing Spondylitis Patients Under Anti-TNF Therapy: A Long-Term Follow-up
Fany Usuba¹, Carla GS Saad², Priscila Novaes¹, Ruth Santo¹, Julio CB Moraes², Eloisa Bonfa³ and Milton Alves⁴, ¹Ophtalmology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ⁴Ophtalmolgy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Clinical expression and pathophysiology of dry eye disease (DED) have recently changed and pro-inflammatory cytokines, such as TNF-α, may play a role in the…
Abstract Number: 1655 • 2018 ACR/ARHP Annual Meeting
Achieving Remission in Psoriatic Arthritis By Early Initiation of TNF Inhibition: A Double-Blind, Randomized, Placebo-Controlled Trial of Golimumab + Methotrexate Versus Placebo + Methotrexate
Leonieke van Mens¹, Jet de Jong², Inka Fluri¹, Marleen van de Sande³, Michael Nurmohamed⁴, M.R. Kok⁵, Arno van Kuijk⁶ and Dominique Baeten², ¹Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³Clinical Immunology & Rheumatology, ARC | Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ⁴Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, ⁵Rheumatology, Maasstad Ziekenhuis, Rotterdam, Netherlands, ⁶Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands
Background/Purpose: In inflammatory arthritis such as RA, early initiation of highly effective targeted treatments is a successful strategy to aim for sustained remission.1 Here we…
Abstract Number: 1656 • 2018 ACR/ARHP Annual Meeting
Is a Positive Family History of Spondyloarthritis Relevant for Diagnosing Axial Spondyloarthritis Once HLA-B27 Status Is Known? Data from the ASAS, DESIR, and SPACE Cohorts
Miranda van Lunteren¹, Désirée van der Heijde¹, Alexandre Sepriano^1,2, Inger Berg³, Maxime Dougados^4,5, Laure Gossec^6,7, Lennart Jacobsson⁸, Roberta Ramonda⁹, Martin Rudwaleit^10,11, Joachim Sieper^11,12, Robert B.M. Landewé^13,14 and Floris van Gaalen¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, NOVA Medical School, Universidade Nova de Lisboa, Lisbon, Portugal, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁵Rheumatology, Paris Descartes University, Cochin Hospital, Paris, France, ⁶Rheumatology, Sorbonne Université, Paris, France, ⁷Rheumatology, Pitié Salpêtrière Hospital, Paris, France, ⁸Rheumatology, University of Gothenburg, Gothenburg, Sweden, ⁹Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, ¹⁰Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany, ¹¹Rheumatology, Charité Campus Benjamin Franklin, Berlin, Germany, ¹²German Rheumatism Research Centre, Berlin, Germany, ¹³Rheumatology, Zuyderland Hospital, Heerlen, Netherlands, ¹⁴Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands
Background/Purpose: A positive family history (PFH) of spondyloarthritis (SpA), in particular a PFH of ankylosing spondylitis (AS) or acute anterior uveitis (AAU), can be used…
Abstract Number: 1657 • 2018 ACR/ARHP Annual Meeting
The Effect of Guselkumab on Enthesitis: Results from a Phase 2 Study in Patients with Active Psoriatic Arthritis
Philip Helliwell¹, Alice B Gottlieb², Atul A. Deodhar³, Wolf-Henning Boehncke⁴, Dennis McGonagle¹, Xie L. Xu⁵, Stephen Xu⁵, Yuhua Wang⁵, Elizabeth C Hsia^5,6, Chetan S Karyekar⁵ and Philip J. Mease⁷, ¹U of Leeds, Leeds, United Kingdom, ²NY Medical College, Metropolitan Hospital, NY, NY, ³Oregon Health & Science U, Portland, OR, ⁴U of Geneva, Geneva, Switzerland, ⁵Janssen Research & Development, LLC, Spring House, PA, ⁶U Penn School of Medicine, Phila, PA, ⁷Swedish Medical Center & U of Wash, Seattle, WA
Background/Purpose: In a Phase 2 study, Guselkumab (GUS) was shown to be safe & effective in pts w/active PsA w/meaningful improvements in enthesitis. To evaluate…
Abstract Number: 1658 • 2018 ACR/ARHP Annual Meeting
Which Factors Influence the Diagnostic Delay in Patients with Axial Spondyloarthritis?
Imke Redeker¹, Johanna Callhoff¹, Falk Hoffmann², Hildrun Haibel³, Joachim Sieper⁴, Angela Zink⁵ and Denis Poddubnyy⁴, ¹Epidemiology Unit, German Rheumatism Research Centre, Berlin, Germany, ²Department of Health Services Research, Carl von Ossietzky University, Oldenburg, Germany, ³Charité Universitätmedizin Berlin, Berlin, Germany, ⁴Rheumatology, Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁵Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany
Background/Purpose: The interval from symptom onset till diagnosis in axial spondyloarthritis (axSpA) was reported a decade ago to be between five and ten years. The…
Abstract Number: 1659 • 2018 ACR/ARHP Annual Meeting
Sustained Improvements in Physical Function, Quality of Life, and Work Productivity after Ixekizumab Therapy in Patients with Active Psoriatic Arthritis: 3-Year Results
Roy Fleischmann¹, Vinod Chandran², Eric Lespessailles³, Julie Birt⁴, Olivier Benichou⁴, Janelle Erickson⁴ and Catherine Shuler⁴, ¹University of Texas Southwestern Medical Center, Dallas, TX, ²Krembil Research Institute and University of Toronto, Toronto, ON, Canada, ³University of Orléans, Orléans, France, ⁴Eli Lilly and Company, Indianapolis, IN
Background/Purpose: Ixekizumab (IXE), a high-affinity mAb that selectively targets IL-17A, has shown improvements compared to placebo not only in disease activity but also in various…

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