Abstract Number: 562 • 2017 ACR/ARHP Annual Meeting
Anti-Muscarinic Receptor 3 Antibodies – a Cross Reactive Result of Ro60 Immunization
Background/Purpose: Sjogren’s syndrome (SS) is a chronic autoimmune inflammatory disease characterized by impaired function of salivary and lacrimal glands leading to dry mouth and dry…Abstract Number: 563 • 2017 ACR/ARHP Annual Meeting
The Effect of Non-Invasive Vagus Nerve Stimulation on Fatigue and Immune Responses in Patients with Primary Sjögren’s Syndrome
Background/Purpose: Primary Sjšgren's syndrome (pSS) sufferers have rated chronic fatigue as the most important symptom needing improvement and the main contributing factor to the loss…Abstract Number: 564 • 2017 ACR/ARHP Annual Meeting
Molecular Identification of a Ro-Specific Salivary IgA Repertoire with Unique Clonal Signatures in Primary Sjogren’s Syndrome
Background/Purpose: Autoantibodies against 60-kD Ro (Ro60)/SSA have been detected in the saliva and serum of patients with primary Sjögren's syndrome (SS) by routine methods that…Abstract Number: 565 • 2017 ACR/ARHP Annual Meeting
Fatigue in Primary Sjögren’s Syndrome (pSS) Is Associated with Lower Levels of Proinflammatory Cytokines: A Validation Study
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune rheumatic disease causing various symptoms including dryness, fatigue and pain. Previous work by our group has…Abstract Number: 566 • 2017 ACR/ARHP Annual Meeting
Immune Response to Seasonal Flu Vaccination in Patients with Primary Sjogren’s Syndrome
Background/Purpose: Vaccination of rheumatic patients has been reported to induce lower antibody titers than in healthy individuals. However, studies have primarily included patients treated with…Abstract Number: 567 • 2017 ACR/ARHP Annual Meeting
Minor Salivary Gland Histopathology, Major Salivary Gland Ultrasonography, and Secretory Function in Smoking Patients with Primary Sjögren’s Syndrome
Background/Purpose: Several studies have reported a protective effect of smoking with regard to risk for primary Sjögren’s syndrome (pSS) and minor salivary gland inflammation. To…Abstract Number: 568 • 2017 ACR/ARHP Annual Meeting
Complement Consumption As a Predictor of Pulmonary Manifestation in Patients with Primary Sjögren’s Syndrome: Results from a Unicentric Observational Study
Complement Consumption as a Predictor of Pulmonary Manifestation in Patients with Primary Sjögren’s Syndrome: Results from a Unicentric Observational StudyBackground/Purpose: Primary Sjögren’s syndrome (pSS) may…Abstract Number: 569 • 2017 ACR/ARHP Annual Meeting
Is the Oral Microbiome Involved in the Pathogenesis of Sjogren’s Syndrome?
Background/Purpose: Environmental factors involved in the pathogenesis of primary Sjögren’s syndrome (pSS) are still largely unknown. The oral cavity is the microbial habitat closest to…Abstract Number: 570 • 2017 ACR/ARHP Annual Meeting
Signalling Pathways Identified in Salivary Glands from Primary Sjögren’s Syndrome Patients Reveal Enhanced Adipose Tissue Development, As Demonstrated By Microarray Analysis, Real-Time PCR and Immunohistochemistry
Background/Purpose: : A characteristic feature of Sjögren’s syndrome (SS) is the destruction of salivary and lacrimal glands mediated by mononuclear cell infiltration. Adipocytes can also…Abstract Number: 571 • 2017 ACR/ARHP Annual Meeting
Anti-Modified Protein Antibody Response Pattern in Primary Sjögren’s Syndrome: Clinical and Prognostic Implications
Background/Purpose: Over the last decades, several post translationally modified proteins have been identified as auto-antigens in rheumatoid arthritis (RA). No data regarding Abs against acetylated…Abstract Number: 572 • 2017 ACR/ARHP Annual Meeting
Biopsy Accuracy in Sjögren’s Syndrome: Analysis of 803 Patients Presenting with Sicca Syndrome Referred to Labial Salivary Gland Biopsy
Background/Purpose: Labial salivary gland biopsy (LSGB) is a minimally invasive procedure used in the diagnostic of Sjögren's Syndrome (SS). Objectives: to describe demographic, clinical and…Abstract Number: 573 • 2017 ACR/ARHP Annual Meeting
Subepithelial Infiltrate of the Vagina in Primary Sjogren’s Syndrome: The Cause of Vaginal Dryness?
Background/Purpose: Women with primary Sjögren’s syndrome (pSS) often experience vaginal dryness. The cause of this symptom is unknown. This study compared the vaginal and cervical…Abstract Number: 574 • 2017 ACR/ARHP Annual Meeting
Is Elastography a New Tool to Differentiate Sjögren Syndrome to Sicca Syndrome?: Results of the Elsa (elastography of salivary glands) Study
Background/Purpose: Ultrasonography (US) has been developed in salivary glands (SG) and particularly in primary Sjögren syndrome (pSS) for 10 years. However, the training curve is…Abstract Number: 575 • 2017 ACR/ARHP Annual Meeting
Distinct Clinical and Immunological Features of Anti-Centromere Antibody Positive Primary Sjögren’s Syndrome: A Single Center Cross-Sectional Cohort Study
Background/Purpose: Anti-centromere antibody (ACA) positive Sjögren’s syndrome (SS) is considered as a subtype in SS. Recent international collaborative large scale cohort study highlighted several clinical…Abstract Number: 576 • 2017 ACR/ARHP Annual Meeting
Immunosignature-Based Diagnosis and Prediction of Therapeutic Response Enables Retrospective Patient Stratification in a Phase IIa Clinical Trial for VAY736 in Primary Sjögren’s Syndrome
Background/Purpose: Although patient stratification can improve the success rate of clinical trials, efforts to apply this strategy to autoimmune studies such as Sjögren’s syndrome are…