Abstracts Archive - Page 1235 of 2607 - ACR Meeting Abstracts

Abstract Number: 730 • 2018 ACR/ARHP Annual Meeting
Accrual of Atherosclerotic Vascular Events over 10 Years in a Multicentre Inception SLE Cohort
Murray Urowitz¹, Dafna D Gladman², Nicole Anderson² and Jiandong Su², ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: The prevalence of atherosclerotic vascular events (AVE) in published literature of an inception cohort with SLE is 10%. We aimed to investigate the annual…
Abstract Number: 731 • 2018 ACR/ARHP Annual Meeting
Clinical Characteristics and Neurophysiological Patterns of Peripheral Neuropathies in Patients with Systemic Lupus Erythematosus: A Single Center Experience
Francisco Treviño-Tello¹, Erwin Chiquete², Christopher Cabib², Ariadna Díaz-Mora¹, Mariana Lopez-Lopez¹, Ivonne Sandoval-Flores¹, Juan José Gómez-Piña² and Hilda Fragoso-Loyo¹, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Neurology and Neuropsychiatry, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
Background/Purpose: The prevalence of peripheral neurological manifestations in Systemic Lupus Erythematosus (SLE) ranges between 5% and 27% and are a major cause of morbidity. The…
Abstract Number: 732 • 2018 ACR/ARHP Annual Meeting
Impact of Disease Course on Atherosclerotic Vascular Events, Osteoporosis and Osteonecrosis in Systemic Lupus Erythematosus
Konstantinos Tselios, Dafna D Gladman, Zahi Touma, Jiandong Su, Nicole Anderson and Murray Urowitz, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: We have shown that disease course over time in systemic lupus erythematosus (SLE) follows three distinct patterns (prolonged remission, relapsing remitting and persistently active).…
Abstract Number: 733 • 2018 ACR/ARHP Annual Meeting
Advanced Chronic Kidney Disease in Lupus Nephritis: Factors Leading to Progression
Konstantinos Tselios, Dafna D Gladman, Jiandong Su and Murray Urowitz, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Advanced chronic kidney disease (CKD) carries an increased risk for progression to end-stage renal disease (ESRD) and renal replacement therapy. However, the rate of…
Abstract Number: 734 • 2018 ACR/ARHP Annual Meeting
The Role of Micro-RNA 142-3p Expression in Lupus Nephritis in an Egyptian Cohort
Marwa Elkhalifa¹, Magdy Zehairy¹, Manal Tayel¹, Ahmed Elkeraie², Dalal Elkaffash³ and Nahed Baddour⁴, ¹Internal medicine, Rheumatology, Faculty of medicine, Alexandria University, Egypt, Alexanderia, Egypt, ²Internal medicine, Nephrology, Faculty of medicine, Alexandria University, Egypt, Alexanderia, Egypt, ³Clinical and Chemical Pathology, Faculty of medicine, Alexandria University, Egypt, Alexanderia, Egypt, ⁴Pathology, Faculty of medicine, Alexandria University, Egypt, Alexanderia, Egypt
Background/Purpose: Micro-RNAs play an important role in regulating gene expression at the posttranscriptional level. Recent data have shown that microRNAs are critical for the development…
Abstract Number: 735 • 2018 ACR/ARHP Annual Meeting
Serum Albumin at One Year Predicts Long-Term Renal Outcome
Vinicius Domingues¹, Daniel Goldman², Laurence S Magder³ and Michelle Petri², ¹Medicine, New York University School of Medicine, New York, NY, ²Medicine (Rheumatology), Johns Hopkins University School of Medicine, Baltimore, MD, ³Epidemiology and Public health, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Lupus nephritis remains a major cause of morbidity/mortality in SLE. Our cohort has shown that 20% of SLE patients with lupus nephritis onset…
Abstract Number: 736 • 2018 ACR/ARHP Annual Meeting
Herpes Zoster and Disseminated Zoster in Systemic Lupus Erythematosus and Lupus Nephritis: Incidence Rates in Real-World Claims Data
Katherine Belendiuk¹, Yingjie Ding², Devika Chawla¹ and Matthew Cascino¹, ¹Genentech, Inc., South San Francisco, CA, ²Genesis Research, Hoboken, NJ
Background/Purpose: Disseminated zoster is a highly morbid complication of varicella zoster reactivation (herpes zoster) that is typically associated with immunosuppression. Systemic lupus erythematosus (SLE) and…
Abstract Number: 737 • 2018 ACR/ARHP Annual Meeting
Atherogenic Index of Plasma in Women with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A 10-Year Potential Predictor of Cardiovascular Disease
Nevin Hammam^1,2 and Tamer A Gheita³, ¹University of Alberta, Edmonton, AB, Canada, ²Rheumatology and Rehabilitation Department, Assiut University, Assiut, Egypt, ³Rheumatology Department Faculty of Medicine, Cairo University, Cairo, Egypt
Background/Purpose: Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are characterized by an increased frequency of cardiovascular diseases (CVD). Early diagnosis of these…
Abstract Number: 738 • 2018 ACR/ARHP Annual Meeting
Two Clinical Phenotypes of Chinese SLE-PAH Patients
Fangfang Sun¹, Wanlong Wu², Li Guo¹, Zhiwei Chen¹, Xiaodong Wang¹, Ting Li¹ and Shuang Ye¹, ¹Rheumatology, Ren Ji Hospital, South Campus, School of Medicine, Shanghai Jiaotong University, Shanghai, China, ²Department of Rheumatology, South Campus, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Background/Purpose: Pulmonary arterial hypertension (PAH) is a severe complication of systemic lupus erythematosus (SLE), which is the most common underlying disease of CTD associated PAH.…
Abstract Number: 739 • 2018 ACR/ARHP Annual Meeting
Urine and Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) Differentially Correlates with Renal and Non-Renal Systemic Lupus Erythematosus (SLE): A Prospective, Case-Control Study
Yair Molad^1,2, Mohammad Egbaria³, Ariela Dortort-Lazar^4,5, Elisheva Pokroy-Shapira^3,5, Shirly Oren⁴, Yonatan Edel^3,5 and Vitaly Kliminski^5,6, ¹Rheumatology Unit, Rabin Medical Center - Beilinson Campus, Petah-Tiqva, Israel, ²Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel, ³Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel, ⁴Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petach Tikva, Israel, ⁵Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁶Laboratory of Inflammation Research, Felsenstein Medical Research Center, Rabin Medical Center, Petach Tikva, Israel
Background/Purpose: Elevated levels of sTREM-1 have been previously found in patients with SLE. A prospective, case-control, longitudinal study aimed to assess the value of urinary…
Abstract Number: 740 • 2018 ACR/ARHP Annual Meeting
Can Monocyte Chemo-Attractant Protein-1differentiate Different Histological Classes in Lupus Nephritis?
Varun Dhir¹, Ranjeeth Kumar Gone², Amit Sandhu³, Aman Sharma⁴, Shefali Sharma⁵, Ritambhra Nada², Sanjay Jain⁶ and Manish Rathi⁷, ¹Internal Medicine (Rheumatology Unit), Postgraduate Institute of Medical Education and Research, Chandigarh, India, Chandigarh, India, ²Postgraduate Institute of Medical Education and Research, Chandigarh, India, ³Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India, ⁴Clinical Immunology and Rheumatology Services, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India, Chandigarh, India, ⁵Postgraduate Institute of Medical Education and Research, Chandigarh, India, Chandigarh, India, ⁶Postgraduate Institute of Medical Education and Research, Chandigarh, India, CHANDIGARH, India, ⁷Department of Nephrology,, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Background/Purpose: Lupus Nephritis one of the commonest manifestations of SLE. Despite being the gold standard in Lupus nephritis, renal biopsy is an invasive procedure with…
Abstract Number: 741 • 2018 ACR/ARHP Annual Meeting
Cardiovascular Risk Re-Classification Using Carotid Ultrasound in Systemic Lupus Erythematosus Patients Is Related to the Damage Produced By the Disease
Juan Carlos Quevedo¹, Iñigo Rúa-Figueroa², Hiurma Sanchez-Perez³, Beatriz-Segura Tejera⁴, De Vera-González AM⁵, Alejandra Gonzalez-Delgado⁶ and Iván Ferraz-Amaro⁷, ¹Rheumatology, Hospital Doctor Negrin, Las Palmas GC, Spain, ²Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ³Division of Rheumatology, Hospital Universitario de Canarias, Tenerife, Spain, ⁴Rheumatology Division, Hospital Insular de Gran Canaria, Las Palmas, Spain, ⁵Division of Central Laboratory. Hospital Universitario de Canarias, San Cristobal de La Laguna, Spain, ⁶Division of Central Laboratory. Hospital Universitario de Canarias., Tenerife, Spain, ⁷Division of Rheumatology.Hospital Universitario de Canarias, Tenerife, Spain
Background/Purpose: Systemic lupus erythematosus (SLE) is associated with an increased in the prevalence of atherosclerosis. Composite scores of cardiovascular risk factors in patients with SLE…
Abstract Number: 742 • 2018 ACR/ARHP Annual Meeting
Moderate to Severe Depression in Patients with Systemic Lupus Erythematosus
Nathalie Chalhoub and Michael Luggen, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH
Background/Purpose: Depression is among the most common neuropsychiatric manifestations in SLE with a prevalence reported to be up to 75% in some studies. Depression in…
Abstract Number: 743 • 2018 ACR/ARHP Annual Meeting
Outcome of Stroke in Patients with Systemic Lupus Erythematosus: A Nested Case-Control Study
Chi Chiu Mok, Lap Kiu Tsoi and Yat Pang Fu, Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose: To evaluate the outcome of stroke in patients with systemic lupus erythematosus (SLE) in comparison with non-SLE patients. Methods: Patients who fulfilled ≥4 SLICC/ACR…
Abstract Number: 744 • 2018 ACR/ARHP Annual Meeting
Association of PCSK9 Serum Levels with Lipid Metabolism Dysregulation, Activity/Damage Scores and Subclinical Atherosclerosis in SLE Patients
Hiurma Sanchez-Perez¹, Juan Carlos Quevedo², Iñigo Rua-Figueroa³, Beatriz Tejera-Segura⁴, De Vera-González AM⁵, Alejandra Gonzalez-Delgado⁶, Federico Díaz-González⁷ and Iván Ferraz-Amaro⁸, ¹Rheumatology, Rheumatology Division, Hospital Universitario de Canarias, La Laguna, Spain, ²Rheumatology, Hospital Doctor Negrin, Las Palmas GC, Spain, ³Division of Rheumatology, Hospital Doctor Negrín, Las Palmas, Spain, ⁴Rheumatology Division, Hospital Insular de Gran Canaria, Las Palmas, Spain, ⁵Division of Central Laboratory. Hospital Universitario de Canarias, San Cristobal de La Laguna, Spain, ⁶Division of Central Laboratory. Hospital Universitario de Canarias., Tenerife, Spain, ⁷Reumatología, Servicio de Reumatología, Hospital Universitario de Canarias,Spain, La Laguna, Spain, ⁸Division of Rheumatology.Hospital Universitario de Canarias, Tenerife, Spain
Background/Purpose: Cardiovascular disease is one of the major causes of morbidity and mortality in patients with systemic lupus erythematosus (SLE). SLE patients are characterized by…

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