Abstracts Archive - Page 1166 of 2607 - ACR Meeting Abstracts

Abstract Number: 449 • 2019 ACR/ARP Annual Meeting
The Course of Disability Related to Function of the Upper Extremities in Early Rheumatoid Arthritis over 10 Years of Follow-up
Maria Rydholm ¹, Ingegerd Wikström ², Maria Mellblom Bengtsson ¹, Sofia Hagel ³, Lennart Jacobsson ⁴ and Carl Turesson², ¹Skåne University Hospital, Malmö, Sweden, ²Lund University, Malmö, Sweden, ³Skåne University Hospital, Lund, Sweden, ⁴Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden,, Gothenburg, Sweden
Background/Purpose: Patients with rheumatoid arthritis (RA) have increased disability, in particular due to involvement of the joints of the upper extremities. The Stanford Health Assessment…
Abstract Number: 450 • 2019 ACR/ARP Annual Meeting
ACPA-positive versus ACPA-negative Rheumatoid Arthritis: Two Distinct Erosive Disease Entities on Radiography and Ultrasonography
Julien Grosse¹, Edem Allado ¹, Camille Roux ¹, Audrey Pierreisnard ², Marion Couderc ³, Isabelle Clerc-Urmès ¹, Thomas Remen ¹, Eliane Albuisson ⁴, Marcelo De Carvalho ¹, Isabelle Chary-Valckenaere ⁴ and Damien Loeuille ⁵, ¹Centre Hospitalier Universitaire de Nancy, Nancy, France, ²APHP, Paris, France, ³CHU G.Montpied, Clermont Ferrand, France, ⁴Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, ⁵Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France
Background/Purpose: Several studies have shown that ACPA-positive (ACPA+) patients were more likely to develop erosive disease on radiography (RX) than ACPA-negative (ACPA-) patients, but it…
Abstract Number: 451 • 2019 ACR/ARP Annual Meeting
Persistent and Non-Articular Regional and Widespread Pain Are Common in Early Rheumatoid Arthritis, Impacting Remission Rates and Reflected in Patient Global Scores
Vivian P. Bykerk¹, Orit Schieir ², Marie-France Valois ³, Gilles Boire ⁴, Glen Hazlewood ⁵, Louis Bessette ⁶, Carol Hitchon ⁷, Diane Tin ⁸, Carter Thorne ⁹, Edward Keystone ¹⁰, Janet Pope ¹¹, Susan J. Bartlett ¹² and Canadian Early Arthritis Cohort (CATCH) Investigators ¹³, ¹Hospital for Special Surgery, New York, NY, ²University of Toronto Dalla Lana School of Public Health, Toronto, ON, Canada, ³McGill University, Montreal, Canada, ⁴Sherbrooke University, Sherbrooke, QC, Canada, ⁵University of Calgary, Calgary, AB, Canada, ⁶Laval University, Quebec City, QC, Canada, ⁷University of Manitoba, Winnipeg, Canada, ⁸Southlake Regional Health Centre, Newmarket, Canada, ⁹Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁰Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada, ¹¹Western University, London, ON, Canada, ¹²McGill University, Montreal, QC, Canada, ¹³Canadian Early Arthritis Cohort (CATCH) Study, Toronto, Canada
Background/Purpose: Persisting pain (NRS ≥4,) (PP) and non-articular pain (NAP), reduces quality of life for patients with RA. NAP is often attributed to fibromyalgia (FM),…
Abstract Number: 452 • 2019 ACR/ARP Annual Meeting
Anti-citrullinated Vimentin Antibodies Are Associated to Early Deterioration of Cortical Bone and Volumetric Bone Mineral Density in Finger Joints in RA-at-risk Patients
Georg Schett¹, David Simon ², Axel Hueber ², Holger Bang ³, Jürgen Rech ⁴, Gerhard Kroenke ⁵ and Arnd Kleyer ⁶, ¹Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, ²Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, ³Orgentec Diagnostika, 55129 Mainz, Germany, Mainz, ⁴Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany, ⁵Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Austria, ⁶Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Autoimmunity, characterized by the presence of anti-modified protein antibodies (AMPA), recognizing citrullinated, carbamylated or acetylated proteins, as well as rheumatoid factor (RF) precedes the…
Abstract Number: 453 • 2019 ACR/ARP Annual Meeting
Including Pain, Fatigue and Functionality Regularly in the Assessment of Patients with Early Rheumatoid Arthritis Separately Adds to the Evaluation of Disease Status
Sofia Pazmino¹, Anikó Lovik ², Annelies Boonen ³, Diederik De Cock ¹, Veerle Stouten ¹, Johan Joly ⁴, Kristien Van der Elst ⁵, Delphine Bertrand ¹, Rene Westhovens ⁶ and Patrick Verschueren ⁵, ¹KU Leuven, Leuven, Belgium, ²Leuven Biostatistics and Statistical Bioinformatics Center, KU Leuven, Leuven, Vlaams-Brabant, Belgium, ³Maastricht University Medical Center, Maastricht, Netherlands, ⁴University Hospitals Leuven, Leuven, Vlaams-Brabant, Belgium, ⁵University Hospital Leuven, Leuven, Belgium, ⁶University Hospitals, Leuven, Belgium
Background/Purpose: Rheumatoid arthritis (RA) level of disease activity, cannot be evaluated by a single clinical or laboratory measurement. Hence, composite indices have been created via…
Abstract Number: 454 • 2019 ACR/ARP Annual Meeting
Principal Component Analysis Identifies Unique Sub-Populations in Rheumatoid Arthritis Using a Combination of Serological Biomarkers: A Cross Sectional Study
Jordan Van Dyk¹, Bryan Heard ¹ and Cheryl Barnabe ¹, ¹University of Calgary, Calgary, AB, Canada
Background/Purpose: Determining the prognosis of rheumatoid arthritis (RA) could guide more precise treatment selection, optimizing outcomes while minimizing unnecessary therapeutic exposures. It is important that…
Abstract Number: 455 • 2019 ACR/ARP Annual Meeting
Anti-Protein-Arginine Deiminase (PAD) 4 IgA Are Present in the Sera of Rheumatoid Arthritis Patients and Are Associated with Joint Erosion and Biological Treatment Use
Laura Martinez-Prat¹, Victor Manuel Martínez Taboada ², Marcos Lopez-Hoyos ³ and Michael Mahler ⁴, ¹Inova Diagnostics, Francisco de Vitoria University, San Diego, CA, ²Hospital Universitario Marqués de Valdecilla, Santander, Spain, ³Hospital Universitario Marqués de Valdecilla-IDIVAL, Santander, Cantabria, Spain, ⁴Inova Diagnostics, San Diego, CA
Background/Purpose: Over the past years, novel biomarkers have been described in rheumatoid arthritis (RA) patients, including autoantibodies to the protein-arginine deiminase (PAD) enzymes. Anti-PAD4 IgG…
Abstract Number: 456 • 2019 ACR/ARP Annual Meeting
Vitamin D Is Not Associated with Treatment Responses in Patients with Newly Diagnosed Rheumatoid Arthritis
Juyeon Kang ¹ and Chan-Bum Choi¹, ¹Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea
Background/Purpose: Vitamin D is known to have immunomodulatory properties and had shown a relationship with susceptibility and disease activity in rheumatoid arthritis (RA). We investigated…
Abstract Number: 457 • 2019 ACR/ARP Annual Meeting
Serum Myostatin in Patients with Rheumatoid Arthritis and Its Correlations with Body Compositions and the Disease Activity
Yoko Wada¹, Masanori Sudo ², Daisuke Kobayashi ², Takeshi Kuroda ³ and Masaaki Nakano ⁴, ¹Niigata Rinko Hospital, Niigata, Niigata, Japan, ²Division of Clinical Nephrology and Rheumatology, Niigata University, Niigata, Niigata, Japan, ³Health administration office, Niigata University, Niigata, Niigata, Japan, ⁴School of Health Sciences, Faculty of Medicine, Niigata University, Niigata, Niigata, Japan
Background/Purpose: Altered body composition is a common feature of patients with rheumatoid arthritis (RA), up to two-thirds of affected patients showing loss of muscle mass…
Abstract Number: 458 • 2019 ACR/ARP Annual Meeting
The Influence of Mediterranean Diet in Rheumatoid Arthritis: A Monocenter Cross-sectional Study
Francesca Ingegnoli¹, Tommaso Schioppo ¹, Isabella Scotti ², Giuseppe Marano ², Patrizia Boracchi ², Orazio De Lucia ³, Antonella Murgo ³ and Roberto Caporali ¹, ¹Division of Clinical Rheumatology, ASST Pini-CTO, Università degli Studi di Milano, Department of Clinical Sciences and Community Health, Milan, Italy, Milano, Italy, ²Università degli Studi di Milano, Milano, Italy, MILANO, Italy, ³Division of Clinical Rheumatology, ASST Pini-CTO, Milan, Italy, Milano, Italy
Background/Purpose: Mediterranean diet (MD) is considered a well-balanced and potentially anti-inflammatory diet characterized by high consumption of olive oil, unrefined cereals, fresh or dried fruit…
Abstract Number: 459 • 2019 ACR/ARP Annual Meeting
The Effects of Erythrocytes and Platelets on Disease Activity in Patients with RA – ANSWER Longitudinal Cohort Study –
Akira Onishi¹, Kengo Akashi ¹, Sadao Jinno ², Yonsu Son ³, Hideki Amuro ³, Toru Hirano ⁴, Yuichi Maeda ⁵, Motomu Hashimoto ⁶, Wataru Yamamoto ⁶, Kosaku Murakami ⁶, Ryota Hara ⁷, Masanori Katayama ⁸, Tohru Takeuchi ⁹, Takuya Kotani ⁹, Jun Saegusa ¹ and Akio Morinobu ¹, ¹Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ²Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Osaka, Japan, ³First Department of Internal Medicine, Kansai Medical University, Osaka, Japan, ⁴Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan, ⁵Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Osaka, Japan, ⁶Department of Advanced Medicine for Rheumatic Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan, ⁷The Center for Rheumatic Disease, Department of Orthopedic Surgery, Nara Medical University, Nara, Japan, ⁸Department of Rheumatology, Osaka Red Cross Hospital, Osaka, Japan, ⁹Department of Internal Medicine IV, Osaka Medical College, Osaka, Japan
Background/Purpose: Experimental models suggested both erythrocytes and platelets activated immune cells and enhanced inflammation in inflammatory arthritis. Although previous cross-sectional studies showed the form and…
Abstract Number: 460 • 2019 ACR/ARP Annual Meeting
Fertility of Women with Rheumatoid Arthritis: Disease Activity Negatively Correlates with Serum AMH Levels
Camille Valdeyron¹, Martin SOUBRIER ², Bruno Pereira ¹, Arnaud Constantin ³, Jacques Morel ⁴, Philippe Gaudin ⁵, Bernard Combe ⁶ and Florence Brugnon ¹, ¹CHU CLERMONT-FERRAND, Clermont-Ferrand, France, ²CHU Gabriel Montpied, Clermont Ferrand, Auvergne, France, ³CHU TOUOUSE, TOULOUSE, France, ⁴CHU MONTPELLIER, MONTPELLIER, France, ⁵Rheumatology Department, CHU Grenoble Alpes Hôpital Sud and GREPI - Université Grenoble Alpes, EA7408, Grenoble - Echirolles, France, ⁶CHU Montpellier, Montpellier University, Montpellier, France
Background/Purpose: Patients with rheumatoid arthritis (RA) display a higher infertility prevalence compared with the general population. Disease-related inflammation and RA treatments are likely to be…
Abstract Number: 461 • 2019 ACR/ARP Annual Meeting
Maximal Improvement in Fatigue Lags Behind Achievement of Sustained Remission in Early Rheumatoid Arthritis
Melissa Holdren¹, Orit Schieir ², Susan J. Bartlett ³, Louis Bessette ⁴, Gilles Boire ⁵, Glen Hazlewood ⁶, Carol Hitchon ⁷, Edward Keystone ⁸, Diane Tin ⁹, Carter Thorne ¹⁰, Vivian Bykerk ¹¹, Janet Pope ¹² and Canadian Early Arthritis Cohort (CATCH) Investigators ¹³, ¹The University of Western Ontario, London, ON, Canada, ²University of Toronto Dalla Lana School of Public Health, Toronto, ON, Canada, ³McGill University, Montreal, QC, Canada, ⁴Laval University, Quebec City, QC, Canada, ⁵Sherbrooke University, Sherbrooke, QC, Canada, ⁶University of Calgary, Calgary, AB, Canada, ⁷University of Manitoba, Winnipeg, Canada, ⁸Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada, ⁹Southlake Regional Health Centre, Newmarket, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹Hospital for Special Surgery, New York City, NY, ¹²Western University, London, ON, Canada, ¹³Canadian Early Arthritis Cohort (CATCH) Study, Toronto, Canada
Background/Purpose: Up to 80% of rheumatoid arthritis patients report clinically relevant fatigue. Fatigue is a complex multi-factorial process that can result in adverse affects on patients'…
Abstract Number: 462 • 2019 ACR/ARP Annual Meeting
The Endogenous Plasma Small RNAome of Rheumatoid Arthritis
Michelle Ormseth¹, Joseph Solus ², Quanhu Sheng ², Fei Ye ², Haocan Song ², Qiong Wu ², Yan Guo ³, Annette Oeser ², Ryan Allen ², Kasey Vickers ² and C. Michael Stein ², ¹Vanderbilt University Medical Center and Veterans Administration: TN Valley Healthcare System, Nashville, ²Vanderbilt University Medical Center, Nashville, ³University of New Mexico, Albuquerque
Background/Purpose: Small RNA (sRNA) sequencing has revealed new classes of sRNAs beyond microRNAs. These sRNAs can regulate genes and are also useful biomarkers of disease.…
Abstract Number: 463 • 2019 ACR/ARP Annual Meeting
High-titer Rheumatoid Factor Impacts Real-life Management Outcomes of Rheumatoid Arthtitis
Cleandro Albuquerque¹, Ana Reis ², Ana Santos ³, Claiton Brenol ⁴, Ivanio Pereira ⁵, Karina Bonfiglioli ⁶, Manoel Bertolo ⁷, Maria Guimarães ⁸, Maria Sauma ⁹, Paulo Filho ¹⁰, Rina Giorgi ¹¹, Sebastião Radominski ¹², Licia Mota ¹ and Geraldo Castelar ³, ¹UnB, Brasília, Brazil, ²UniCeub, Brasília, Brazil, ³UERJ, Rio de Janeiro, Brazil, ⁴Universidade Federal do Rio Grande do Sul, Porto Alegre, ⁵UFSC, Florianópolis, Brazil, ⁶Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, ⁷University of Campinas, Campinas, Brazil, ⁸UFMG, Belo Horizonte, Brazil, ⁹UFPA, Belém, Brazil, ¹⁰USP, São Paulo, Brazil, ¹¹Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil, ¹²Universidade Federal do Paraná, Curitiba, Brazil
Background/Purpose: The rheumatoid factors (RF) have established roles in rheumatoid arthritis (RA) diagnosis, prediction of disease onset and drug response, and in classifying patients as…

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