ACR Meeting Abstracts

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  • Abstract Number: 2212 • 2018 ACR/ARHP Annual Meeting

    Feasibility and Performance of HR-pQCT-Derived Joint Space Width Measurement As Outcome Parameter in Arthropathic Disease – Lessons from Hemochromatosis Arthropathy

    Ursula Heilmeier1, Andrew J Burghardt1, Puneet Kapoor2, Georg Schett3, Reinhard Voll4 and Stephanie Finzel5, 1Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany, 4Clinic for Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 5Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

    Background/Purpose: High resolution peripheral quantitative computed tomography (HR-pQCT) allows in vivo 3 D imaging of human joint microstructure and joint space width (JSW) at an…
  • Abstract Number: 2213 • 2018 ACR/ARHP Annual Meeting

    Usefulness of Shoulder Radiographs to Aid in Determining Need for Advanced Imaging to Detect Operable or Inoperable Full-Thickness Rotator Cuff Tears

    Ryan Hoggan1, Andrea Barker2, Zhenhao Liu3, Curry L. Koening4 and Michael J. Battistone5, 1University of Utah, Salt Lake City, UT, 2Veterans Affairs Salt Lake City Health Care System and University of Utah School of Medicine, Salt Lake City, UT, 3Rheumatology, University of Utah, Salt Lake City, UT, 4Division of rheumatology, George E. Wahlen Department of Veterans Affairs Medical Center Salt Lake City and University of Utah, University of Utah School of Medicine, Salt Lake City, UT, 5Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT

    Background/Purpose: Full-thickness rotator cuff tears (FTT) can be a debilitating cause of shoulder pain and loss of function. Delay in surgical evaluation may result in…
  • Abstract Number: 2214 • 2018 ACR/ARHP Annual Meeting

    Lung Involvement in Primary Sjögren’s Syndrome: Spectrum of Pulmonary Abnormalities and Computed Tomography Findings

    Janet Flores1, Diego Baenas2, Nadia Riscanevo3, Emanuel Saad4, Maria Jezabel Haye Salinas5, Soledad Retamozo6, Ana C. Alvarez5, Alejandro Alvarellos7, Juan Pablo Pirola8, Nadia Benzaquén5, Verónica Saurit9 and Francisco Caeiro8, 1Rheumatology Unit, Hospital privado Universitario de Córdoba, Cordoba, Argentina, 2Reumatologia, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, 3Rheumatology, Rheumatology Unit, Hospital privado Universitario de Córdoba, Cordoba, Argentina, 4Internal medicine, Hospital Privado, Cordoba, Argentina, 5Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, 6Sociedad Argentina de Reumatologia, Córdoba, Argentina, 7Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 8Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, 9Hospital Privado Centro Médico de Córdoba, Cordoba, Argentina

    Background/Purpose: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that affects exocrine glands. It can generate pulmonary compromise due to dysfunction of the glandular…
  • Abstract Number: 2215 • 2018 ACR/ARHP Annual Meeting

    Evaluation of Left Ventricular Systolic and Diastolic Myocardial Function in Patients with Ankylosing Spondylitis By Speckle-Tracking Echocardiography

    Hang Yang1, Yi Zhao1, Yujia Liang2, Wenkai Yan3, Yi Liu4, Lingshu Zhang1 and Tony Marion5, 1Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China, 2Department of Cardiology, West China Hospital, Sichuan University, CHENGDU, China, 3Southern Medical University, GUANGZHOU, China, 4Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, Sichuan, China, Chengdu, China, 5Immunology and Biochemistry University of Tennessee Health Science Center, Memphis, TN

    Background/Purpose: Patients with ankylosing spondylitis (AS) are at increased risk for cardiovascular disease (CVD), although strategies to detect subclinical CVD are poorly characterized. The aim…
  • Abstract Number: 2216 • 2018 ACR/ARHP Annual Meeting

    Detection of Left Ventricular Regional Function in Primary Sjögren’s Syndrome Patients without Cardiac Symptons, As Assessed By Feature Tracking Cardiac Magnetic Resonance Imaging

    Atsuma Nishiwaki1, Natsumi Ikumi2, Hitomi Kobayashi3,4, Yasuyuki Kobayashi5, Isamu Yokoe4, Yosuke Nagasawa6, Kaita Sugiyama6, Takamasa Nozaki6, Mitsuhiro Iwata4, Noboru Kitamura4 and Masami Takei4, 1Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, 4Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 5Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 6Nihon University School of Medicine, Tokyo, Japan

    Background/Purpose: The risk of major cardiovascular (CV) events and the long-term CV outcome in patients with primary Sjögren’s syndrome (pSS) remain unclear. Myocardial disease is…
  • Abstract Number: 2217 • 2018 ACR/ARHP Annual Meeting

    Clinical Characteristics of Early Onset Gout in Outpatient Setting

    Yan Li1, Paramarajan Piranavan1, Devi Sundaresan2 and Robert A. Yood3, 1Internal Medicine, St. Vincent Hospital, Worcester, MA, 2Research, Reliant Medical Group, Worcester, MA, 3Reliant Medical Group, Worcester, MA

     Background/Purpose: There has been an increase in the prevalence of gout over the past two decades, with increasing number of patients presenting at younger age.…
  • Abstract Number: 2218 • 2018 ACR/ARHP Annual Meeting

    Use of Anakinra in Hospitalized Patients with Acute Crystalline Arthritis

    Jean Liew and Gregory Gardner, Rheumatology, University of Washington, Seattle, WA

    Background/Purpose: Medically complex individuals may have contraindications to standard therapies for acute arthritis secondary to gout or calcium pyrophosphate disease (CPPD). Observational studies have demonstrated…
  • Abstract Number: 2219 • 2018 ACR/ARHP Annual Meeting

    Safety, Pharmacokinetics and Pharmacodynamics of NC-2500, a Novel Xanthine Oxidoreductase Inhibitor, in Healthy Volunteers

    Masuharu Hirano1, Shiro Kobayashi2, Eri Miyayama2, Takashi Ohta1, Masao Yamamoto2 and Tomio Yamakawa3, 1Discovery Research Laboratories, Nippon Chemiphar Co., Ltd., Misato, Saitama Prefecture, Japan, 2Development Planning Department, Nippon Chemiphar Co., Ltd., Chiyoda-ku, Tokyo, Japan, 3Discovery Research Laboratories, Nippon Chemiphar Co., Ltd., Misato, Saitama prefecture, Japan

    Background/Purpose: Gout flare due to rapid urate reduction after initiating urate-lowering therapy (ULT) is one of the major issues in the therapy. International guidelines recommend…
  • Abstract Number: 2220 • 2018 ACR/ARHP Annual Meeting

    Gout, Flares and Allopurinol Use: A Population Based Study

    Charlotte Proudman1, Susan Lester2,3, David Gonzalez-Chica4, Tiffany Gill3, Nicola Dalbeth5 and Catherine Hill6,7, 1Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia, 2Rheumatology Unit, The Queen Elizabeth Hospital, Adelaide, Australia, 3Discipline of Medicine, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia, 4Discipline of General Practice, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia, 5Department of Medicine, Faculty of Medical and Health Sciences., University of Auckland, Auckland, New Zealand, 6The Queen Elizabeth Hospital, Adelaide, Australia, 7Medicine, The University of Adelaide, Adelaide, Australia

    Background/Purpose: Gout flares may often be self-managed, but there is a paucity of population-based data. The aim of this study was to determine the prevalence…
  • Abstract Number: 2221 • 2018 ACR/ARHP Annual Meeting

    Systematic Genetic Analysis of Early-Onset Gout: ABCG2 141K Is the Strongest Predictor

    Faseeh Zaidi1, Amanda Phipps-Green2, Anne-Kathrin Tausche3, Alexander So4, Philip Riches5, Mariano Andres6, Fernando Perez-Ruiz7, Michael Doherty8, Matthijs Janssen9, Leo .A.B. Joosten10, Tim Jansen11, Fina Kurreeman12, Rosa Torres13, Geraldine M. McCarthy14, Jeffrey Miner15, Lisa K. Stamp16, Tony R. Merriman2 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2University of Otago, Dunedin, New Zealand, 3Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany, 4University of Lausanne, Lausanne, Switzerland, 5University of Edinburgh, Edinburgh, United Kingdom, 6Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain, 7BioCruces Health Research Institute, Barakaldo, Spain, 8The University of Nottingham, Nottingham, United Kingdom, 9Rheumatology Dept, Rijnstate Hospital, Arnhem, Netherlands, 10Radboud University Medical Center, Nijmegen, Netherlands, 11VieCuri Medical Center, Venlo, Netherlands, 12Leiden University Medical Centre, Leiden, Netherlands, 13La Paz University Hospital, Madrid, Spain, 14Mater Misericordiae University Hospital, Dublin, Ireland, 15Formerly Ardea Biosciences, San Diego, CA, 16University of Otago, Christchurch, New Zealand

    Background/Purpose:  Although increasing age is an important risk factor for development of gout, disease can develop in younger people. The aim of this study was…
  • Abstract Number: 2222 • 2018 ACR/ARHP Annual Meeting

    Construct Validity of Provisional Remission Criteria for Gout: A Dual Energy CT Study

    Nicola Dalbeth1, Christopher Frampton2, Maple Fung3, Scott Baumgartner3, Savvas Nicolaou4 and Hyon K. Choi5, 1University of Auckland, Auckland, New Zealand, 2University of Otago, Christchurch, New Zealand, 3Formerly Ardea Biosciences, San Diego, CA, 4Radiology, University of British Columbia, Vancouver, BC, Canada, 5Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA

    Background/Purpose: Provisional domains and definitions for gout remission criteria have been proposed using consensus methodology (de Lautour et al, Arthritis Care Res 2016). These criteria…
  • Abstract Number: 2223 • 2018 ACR/ARHP Annual Meeting

    Proton Pump Inhibitors and Risk of Calcium Pyrophosphate Deposition (CPPD) in a Population-Based Study

    Tuhina Neogi1, Christine Peloquin1, Yuqing Zhang1,2, Hyon K. Choi3, Robert Terkeltaub4 and David T. Felson1, 1Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 4VA San Diego Healthcare System, San Diego, CA

    Background/Purpose: There are no therapies available that specifically target CPPD, with treatment limited to symptomatic management. Hypomagnesemia is a recognized risk factor for CPPD, and…
  • Abstract Number: 2224 • 2018 ACR/ARHP Annual Meeting

    Interactions between Serum Urate-Associated Genetic Variants and Sex on Gout Risk in a European Population

    Ravi K. Narang1, Ruth Topless2, Murray Cadzow3, Gregory Gamble4, Lisa K. Stamp5, Tony R. Merriman3 and Nicola Dalbeth6, 1Bone and Joint Research Group, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand, 2Department of Biochemistry, University of Otago, Dunedin, New Zealand, 3University of Otago, Dunedin, New Zealand, 4Department of Medicine, University of Auckland, Auckland, New Zealand, 5University of Otago, Christchurch, New Zealand, 6Department of Medicine, Faculty of Medical and Health Sciences., University of Auckland, Auckland, New Zealand

    Background/Purpose: Sex-specific differences in the effect size of genetic variants on serum urate levels have been described, with SLC2A9 variants having a greater influence on…
  • Abstract Number: 2225 • 2018 ACR/ARHP Annual Meeting

    Exploring the Relationship between Gout and Diffuse Idiopathic Skeletal Hyperostosis (DISH): An Epidemiologic and Genetic Study

    Michael Corkill1, Ruth Topless2, Adam Worthington3, Robert Mitchell3, Kate Gregory3, Lisa K. Stamp4, Matthew Brown5, Tony R. Merriman2 and Nicola Dalbeth6, 1North Shore Hospital, Auckland, New Zealand, 2University of Otago, Dunedin, New Zealand, 3Waitemata District Health Board, Auckland, New Zealand, 4University of Otago, Christchurch, New Zealand, 5Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, 6University of Auckland, Auckland, New Zealand

    Background/Purpose:  Gout has been reported to be a risk factor for development of diffuse idiopathic skeletal hyperostosis (DISH), a condition characterized by abnormal bone formation…
  • Abstract Number: 2226 • 2018 ACR/ARHP Annual Meeting

    Gout and the Risk of Incident Dementia in the Elderly: A Medicare Claims Study

    Jasvinder A. Singh1 and John Cleveland2, 1Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: The pursuit of a link between gout/hyperuricemia and dementia has led to contradictory results.  Most observational studies, including population-based studies, showed that hyperuricemia was…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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