Abstract Number: 1941 • 2018 ACR/ARHP Annual Meeting
Altered Cognitive Function in Systemic Lupus Erythematosus and Associations with Inflammation and Functional Brain Changes
Background/Purpose: Cognitive dysfunction is a common problem in systemic lupus erythematosus (SLE) but the cause is still unclear; measuring it can be difficult and, as…Abstract Number: 1942 • 2018 ACR/ARHP Annual Meeting
Anti-NMDA Receptor Antibodies in Systemic Lupus Erythematosus Associate with Decreased White Matter Integrity and Impaired Spatial Memory
Background/Purpose: Cognitive impairment is common in SLE and impacts quality of life; however, causality is limited by incomplete understanding of neurotoxic mechanisms. Diffusion tensor imaging…Abstract Number: 1943 • 2018 ACR/ARHP Annual Meeting
Apolipoprotein L1 Risk Variants Associate with Poor Renal Outcomes, Damage Accrual, and Death: A Prospective Ghanaian SLE Cohort
Background/Purpose: Two Apolipoprotein L1 (APOL1) risk variants (RV), G1 and G2, are enriched in ancestrally African populations due to a conferred superior resistance to Trypanosoma…Abstract Number: 1944 • 2018 ACR/ARHP Annual Meeting
Does Renin Angiotensin System Blockade in Addition to Immunosuppressive Therapy Improve Proteinuria in Acute Lupus Nephritis?
Background/Purpose: Angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are currently recommended for patients with lupus nephritis (LN) as an adjunctive therapy for…Abstract Number: 1945 • 2018 ACR/ARHP Annual Meeting
Early Prediction of Long-Term Renal Outcomes in Lupus Nephritis Using Hazard Index Equations
Background/Purpose: Early endpoints predicting long-term outcome in lupus nephritis (LN), which could be used as outcome measures in clinical trials, are still debated. Recently, a…Abstract Number: 1946 • 2018 ACR/ARHP Annual Meeting
Changing the Conversation about Pain: Development and Testing of an Interprofessional Pain CME Applicable for Rheumatologists and Rheumatology Health Professionals
Background/Purpose: Pain is a near universal symptom of rheumatic diseases. Persistent pain can cause changes in the central and peripheral nervous system transforming pain from…Abstract Number: 1947 • 2018 ACR/ARHP Annual Meeting
Do Changes in Pain Sensitization and Depressive Symptoms Mediate the Effect of Extreme Weight Loss on Knee Pain Improvement?
Background/Purpose: We previously showed that the one-year effects of weight loss on knee pain reduction were not mediated by changes in structural features of osteoarthritis…Abstract Number: 1948 • 2018 ACR/ARHP Annual Meeting
Beliefs and Preferences for Reducing Sedentary Time in Those with Current or Past Knee Symptoms
Background/Purpose: Physical activity is beneficial for those with current or previous knee symptoms, yet few meet federal physical activity guidelines. Reducing sedentary time, which has…Abstract Number: 1949 • 2018 ACR/ARHP Annual Meeting
Implementation of a Health Diary for Patients with Fibromyalgia
Background/Purpose: Fibromyalgia (FM) is a syndrome of central sensitization that encompasses many disorders where the central nervous system amplifies sensory input across many organ systems…Abstract Number: 1950 • 2018 ACR/ARHP Annual Meeting
Self-Reported Depression and Anxiety Among US Adults Aged 18-44 Years with Arthritis, National Health Interview Survey 2014-2016
Background/Purpose: Depression and anxiety are frequent comorbid conditions among adults with arthritis, and are associated with poorer quality of life, reduced adherence and efficacy of…Abstract Number: 1951 • 2018 ACR/ARHP Annual Meeting
The Effect and Psychosocial Impact of a Longstanding Telephone Peer Counseling Service on Volunteers with Systemic Lupus Erythematosus
Background/Purpose: Studies have demonstrated the value of peer volunteers providing psychosocial support to people living with rheumatic & other chronic conditions. An evaluation was conducted…Abstract Number: 1952 • 2018 ACR/ARHP Annual Meeting
Experimental Tendinopathy Treatment with SM04755, a Topical Small Molecule Inhibitor of the Wnt Pathway
Background/Purpose: Tendinopathy is an inflammatory and degenerative disorder caused by injuries and overuse. The Wnt pathway is upregulated in chronic tendinopathy and involved in inflammation,…Abstract Number: 1953 • 2018 ACR/ARHP Annual Meeting
Randomized Trial on Exercise at Late-Stage after Total Knee Replacement
Background/Purpose: Total knee replacement (TKR) improves pain and quality of life; however, the functional limitations that existed for years before surgery tend to persist after…Abstract Number: 1954 • 2018 ACR/ARHP Annual Meeting
Factors Associated with Overweight or Obesity in Athletes 5 Years after Anterior Cruciate Ligament Injury
Background/Purpose: Obesity and knee injury, including anterior cruciate ligament (ACL) rupture, are strong risk factors for the development of knee osteoarthritis. Identifying participant and post-injury…Abstract Number: 1955 • 2018 ACR/ARHP Annual Meeting
Race Is Associated with Discharge Disposition after Total Knee Arthroplasty (TKA), Which Is Associated with 90-Day Readmission Rate
Background/Purpose: To assess whether race/ethnicity is associated with differences in discharge disposition after elective primary total knee arthroplasty (TKA), and if discharge disposition is associated…
ACR Meeting Abstracts