ACR Meeting Abstracts

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  • Abstract Number: 2467 • 2019 ACR/ARP Annual Meeting

    Pain and Anxiety Are Independent Factors Associated to Sleep Impairment in Psoriatic Arthritis: A Multicentric Study in 14 Countries

    Penelope Palominos1, Laura Coates 2, Charles Kohem 3, Ana-Maria Orbai 4, Josef Smolen 5, Maarten de Wit 6, Uta Kiltz 7, Ying-Ying Leung 8, Juan Cañete 9, Rossana Scrivo 10, Andra Balanescu 11, Emmanuelle Dernis 12, Sandra Talli 13, Martin SOUBRIER 14, Sibel Zehra Aydin 15, Inna Gaydukova 16, Umut Kalyoncu 17 and Laure Gossec 18, 1Serviço de Reumatologia, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul,, Porto Alegra, Brazil, 2University of Oxford, Oxford, United Kingdom, 3Serviço de Reumatologia, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 4Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, Baltimore Maryland, 5Medical University of Vienna, Vienna, Austria, 6Department of Medical Humanities, Amsterdam Public Health (APH), Amsterdam University Medical Centre, Amsterdam, Netherlands, 7Rheumazentrum Ruhrgebiet/Ruhr University Bochum, Herne, Germany, Herne, Germany, 8Department of Rheumatology and Immunology, Singapore General Hospital,, Singapore, Singapore, 9Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Spain, 10Rheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza Università di Roma,, Rome, Italy, 11Sf Maria Hospital, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, 12Rheumatology Department, Le Mans Central Hospital, Le Mans, France, 13Rheumatology Department, East-Tallinn Central Hospital, Tallinn, Estonia, 14CHU Gabriel Montpied, Clermont Ferrand, Auvergne, France, 15University of Ottawa Faculty of Medicine, Rheumatology,Ottawa Hospital Research Institute, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, CANADA, Ottawa, Canada, 16North-western State medical university, St Petersburg, Russia, 17Hacettepe University Department of Rheumatology, Ankara, Turkey, 18Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France

    Background/Purpose: Sleep quality is diminished in patients with psoriatic arthritis (PsA) and close to 40% of PsA patients consider sleep impairment a priority domain.This work…
  • Abstract Number: 2468 • 2019 ACR/ARP Annual Meeting

    JAK-STAT Signaling System in Pannus Formation of Psoriatic Arthritis: A Therapeutic Target

    Siba Raychaudhuri1 and Smritikana Raychaudhuri 2, 1UC Davis School of Medicine, Sacramento, CA, 2UC Davis School of Medicine, Davis, CA

    Background/Purpose: Psoriatic arthritis (PsA) involves inflammation of the joint synovium where synovial cells (FLS) are the target for T cell activated cytokines for pannus formation.…
  • Abstract Number: 2469 • 2019 ACR/ARP Annual Meeting

    Diversity of Poly-Functional T Cells in Psoriatic Arthritis and Rheumatoid Arthritis and Its Therapeutic Significance

    Siba Raychaudhuri1 and Smritikana Raychaudhuri 2, 1UC Davis School of Medicine, Sacramento, CA, 2UC Davis School of Medicine, Davis, CA

    Background/Purpose: Importance to specific T cell subpopulations has been attributed for specific diseases such as Th17 cells in psoriatic disease, Th1 cells in TB and…
  • Abstract Number: 2470 • 2019 ACR/ARP Annual Meeting

    Relationship Between Serum Calprotectin Level and Presence of Subclinical Atherosclerosis and Arterial Stiffness in Patient with Psoriatic Arthritis

    Isaac T. Cheng1, Martin M Li 1, Edmund K Li 1, Alex P Lee 1 and Lai-Shan Tam 1, 1The Chinese University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: Calprotectin is a member of S100 leukocyte. Serum calprotectin is a sensitive biomarker of disease activity in patients with psoriatic arthritis (PsA). While various…
  • Abstract Number: 2471 • 2019 ACR/ARP Annual Meeting

    Regional Difference in Disease Burden Among Patients with Psoriatic Arthritis: A Multi-Center Study

    Erkan Kilic1, Gamze Kilic 2, Kemal Nas 3, Betul Sargin 4, Sevtap Acer Kasman 5, Hakan Alkan 6, Nilay Sahin 7, Gizem Cengiz 8, Nihan Cuzdan 9, Ilknur Albayrak Gezer 10, Dilek Keskin 11, Cevriye Mulkoglu 12, Hatice Resorlu 13, Ismihan Sunar 14, Ajda Bal 15, Mehmet Tuncay Duruoz 5, Okan Kucukakkas 16, Ozan Volkan Yurdakul 16, Meltem Alkan Melikoglu 17, Yildiray Aydin 3, Fikriye Figen Ayhan 18, Hatice Bodur 19, Mustafa Calis 8, Erhan Capkin 20, Gul Devrimsel 21, Kevser Gök 22, Sami Hizmetli 23, Ayhan Kamanli 3, Yasar Keskin 16, Hilal Kocabas 24, Oznur Kutluk 25, Nesrin Sen 26, Omer Faruk Sendur 27, Ibrahim Tekeoglu 3, Sena Tolu 28, Murat Toprak 29 and Tiraje Tuncer 25, 1Afyonkarahisar State Hospital, Afyonkarahisar, Turkey, 2Karadeniz Technical University School of Medicine, Department of Physical Medicine and Rehabilitation, Trabzon, 3Sakarya University School of Medicine, PMR Department, Rheumatology and Immunology Division, Sakarya, Turkey, 4Adnan Menderes University School of Medicine, PMR Department, Rheumatology Division, Aydın, Turkey, 5Marmara University School of Medicine, PMR Department, Rheumatology Division, İstanbul, Turkey, 6Pamukkale University School of Medicine, PMR Department, Rheumatology Division, Denizli, Turkey, 7Balıkesir University School of Medicine, PMR Department, Balıkesir, Turkey, 8Erciyes University School of Medicine, PMR Department, Rheumatology Division, Kayseri, Turkey, 9Şanlıurfa Training and Research Hospital, Rheumatology Clinic, Şanlıurfa, Turkey, 10Selçuk University School of Medicine, PMR Department, Konya, Turkey, 11Kırıkkale University School of Medicine, PMR Department, Kırıkkale, Turkey, 12Ankara Training and Research Hospital, PMR Clinic, Ankara, Turkey, 13Çanakkale Onsekiz Mart University School of Medicine, PMR Department, Çanakkale, Turkey, 14Ankara Unversity School of Medicine, Physical Medicine and Rehabilitation, Rheumatology Department, Ankara, Turkey, 15Dışkapı Yıldırım Beyazıt Training and Research Hospital, PMR Clinic, Ankara, Turkey, 16Bezmialem Vakıf University School of Medicine, PMR Department, İstanbul, Turkey, 17Atatürk University School of Medicine, PMR Department, Rheumatology Division, Erzurum, Turkey, 18Uşak University School of Health Sciences, PMR Department, Uşak, Turkey, 19Yıldırım Beyazıt University School of Medicine, PMR Department, Ankara, Turkey, 20Karadeniz Teknik University School of Medicine, PMR Department, Trabzon, Turkey, 21Recep Tayyip Erdoğan University School of Medicine, PMR Department, Riza, Turkey, 22Numune Training and Research Hospital, Rheumatology Clinic, Ankara, Turkey, 23Cumhuriyet University School of Medicine, PMR Department, Rheumatology Division, Sivas, Turkey, 24Necmettin Erbakan University Meram School of Medicine, PMR Department, Rheumatology Division, Konya, Turkey, 25Akdeniz University School of Medicine, PMR Department, Rheumatology Division, Antalya, Turkey, 26Kartal Dr. Lütfi Kırdar Training and Research Hospital, Rheumatology Clinic, İstanbul, Turkey, 27Adnan Menderes University School of Medicine, PMR Department, Aydın, Turkey, 28Medipol University School of Medicine, PMR Department, İstanbul, Turkey, 29Yüzüncü Yıl University School of Medicine, PMR Department, Van, Turkey

    Background/Purpose: Psoriatic arthritis (PsA) has been defined as an inflammatory arthritis associated with psoriasis. The disease activity can be evaluated using many scales in patients…
  • Abstract Number: 2472 • 2019 ACR/ARP Annual Meeting

    The Role of Ultrasound for the Assessment of Psoriatic Arthritis Patients with Fibromyalgia – Interim Analysis

    Ari Polachek1, Victoria Furer 2, Mirna Zureik 2, Sharon Nevo 2, Liran Mendel 2, David Levartovsky 3, Jonathan Wollman 4, Valerie Aloush 5, Mark Berman 6, Ilana Kaufman 6, Yael Lahat 2, Hagit Sarbagil-Maman 7, Sara Borok 6, Adi Broyde 6, Lihi Eder 8, Daphna Paran 1 and Ori Elkayam 9, 1Tel-Aviv Sourasky medical center, Tel Aviv, Israel, 2Sourasky Medical Center, Tel-Aviv, Israel, 3Sourasky medical center, Tel Aviv, Israel, 4Sourasky Medical Center, Herzelia, Israel, 5Tel Aviv Sourasky medical center, Tel Aviv, 6Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 7Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, 8Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada, 9Rheumatology Department, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel., Tel Aviv, Israel

    Background/Purpose: Psoriatic arthritis is a chronic inflammatory disease. More than 20% of patients with PsA patients suffer from fibromyalgia, a chronic pain syndrome characterized by…
  • Abstract Number: 2473 • 2019 ACR/ARP Annual Meeting

    Implementing the Psoriatic Arthritis Disease Activity Score (PASDAS) in Routine Clinical Practice: (im)possible?

    Michelle Mulder1, Alfons den Broeder 1, Berbke van Ginneken 1, Elien Mahler 1, Frank van den Hoogen 1, Johanna Vriezekolk 1 and Mark Wenink 1, 1Sint Maartenskliniek, Nijmegen, Netherlands

    Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease, with involvement of at least five health domains: peripheral joint disease, enthesitis, dactylitis, axial involvement, and skin…
  • Abstract Number: 2474 • 2019 ACR/ARP Annual Meeting

    Impact of Multidomain Disease Presentations on Overall Disease Burden Among Patients with Psoriatic Arthritis: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Alexis Ogdie1, Peter Hur 2, Mei Liu 3, Sabrina Rebello 3, Robert McLean 3, Blessing Dube 3, Meghan Glynn 4 and Philip Mease 5, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3Corrona, LLC, Waltham, MA, 4Corrona, LLC, Waltham, 5Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic inflammatory disease with heterogeneous presentations that may involve peripheral arthritis, axial disease, enthesitis, dactylitis, and psoriatic skin and…
  • Abstract Number: 2475 • 2019 ACR/ARP Annual Meeting

    Prevalence of Disease Domain Presentations Among Patients with Psoriatic Arthritis: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Alexis Ogdie1, Peter Hur 2, Mei Liu 3, Sabrina Rebello 3, Robert McLean 3, Blessing Dube 3, Meghan Glynn 4 and Philip Mease 5, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3Corrona, LLC, Waltham, MA, 4Corrona, LLC, Waltham, 5Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease of the skin and musculoskeletal system. Six key domains of PsA have been identified to…
  • Abstract Number: 2476 • 2019 ACR/ARP Annual Meeting

    Side Effects of Methotrexate and TNFi: Differences in Tolerability Among Patients with PsA and RA

    Alexis Ogdie1, Ervant Maksabedian 2, Bradley Stolshek 2, Yomei Shaw 3 and Kaleb Michaud 4, 1University of Pennsylvania, Philadelphia, PA, 2Amgen Inc., Thousand Oaks, CA, 3FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, 4FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS

    Background/Purpose: Methotrexate (MTX) is generally well tolerated in rheumatoid arthritis (RA) but little is known about the tolerability of MTX in psoriatic arthritis (PsA).  One…
  • Abstract Number: 2477 • 2019 ACR/ARP Annual Meeting

    Burden of Disease at Treatment Initiation Among Biologic-Naïve Patients with Oligoarticular versus Polyarticular Psoriatic Arthritis in the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Alexis Ogdie1, Mei Liu 2, Meghan Glynn 3, Kelechi Emeanuru 2, Leslie Harrold 4, Sven Richter 5, Benoit Guerette 5 and Philip Mease 6, 1Department of Medicine and Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4Corrona, LLC and University of Massachusetts Medical School, Worcester, MA, 5Celgene Corporation, Summit, 6Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Oligoarticular PsA accounts for ≈50% of PsA worldwide, but only a paucity of data describes disease burden among these patients. The Corrona PsA/SpA Registry,…
  • Abstract Number: 2478 • 2019 ACR/ARP Annual Meeting

    Enthesitis Frequency and Treatment Patterns in Patients with Psoriatic Arthritis in Europe and Japan

    Daniel Aletaha1, Patrick Zueger 2, Naijun Chen 2 and Nicola Booth 3, 1Medical University of Vienna, Vienna, Austria, 2AbbVie Inc., North Chicago, IL, 3Adelphi Real World, Bollington, United Kingdom

    Background/Purpose: Enthesitis, a symptom commonly associated with psoriatic arthritis (PsA), negatively affects quality of life. Although enthesitis is routinely reported in randomized clinical trials of…
  • Abstract Number: 2479 • 2019 ACR/ARP Annual Meeting

    Unmet Treatment Needs in Patients with Psoriatic Arthritis

    Daniel Aletaha1, Mihalina Georgallis 2, Matthew Wallace 2, Patrick Zueger 3 and Ruth Zeidman 2, 1Medical University of Vienna, Vienna, Austria, 2Covance Market Access & Phase IV Solutions, London, United Kingdom, 3AbbVie Inc., North Chicago

    Background/Purpose: Despite significant advances in the treatment of psoriatic arthritis (PsA), disease control and remission remain a challenge. Research characterizing residual disease burden with current…
  • Abstract Number: 2480 • 2019 ACR/ARP Annual Meeting

    Opioid Use Surrounding Diagnosis of Inflammatory Arthritis

    Anna Sheahan1, Victor Sloan 1, Jeffrey Stark 2 and Robert Suruki 1, 1UCB Pharma, Raleigh, NC, 2UCB Pharma, Smyrna, GA

    Background/Purpose: Although treatment of inflammatory arthritis (IA) has improved, opioid use among patients remains common. A study from Finland showed increases in opioid use leading…
  • Abstract Number: 2481 • 2019 ACR/ARP Annual Meeting

    Uveitis in 320 Patients with Psoriatic Arthritis. Epidemiology, Clinical Features and Biological Treatment: Study from a Single University Center

    Iñigo Gonzalez-Mazon1, Lara Sanchez-Bilbao 2, Natalia Palmou-Fontana 1, DAVID MARTINEZ-LOPEZ 3, Mónica Calderón-Goercke 4, DIANA PRIETO- PENA 1, Susana Armesto-Alonso 3, Miguel A Gonzalez-Gay 2 and Ricardo Blanco 2, 1Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, 2Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, 4Hospital Marqués de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: Uveitis is an extra articular manifestation of psoriatic arthritis (PsA). Uveitis may be more chronic Biological therapy, especially monoclonal TNF inhibitors, are useful to…
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