Abstracts Archive - Page 1112 of 2607 - ACR Meeting Abstracts

Abstract Number: 2579 • 2019 ACR/ARP Annual Meeting
A Quality Improvement Project in Determining If Cardiac Enzymes Play a Role in Surveillance of Possible Hydroxychloroquine Induced Cardiotoxicity
Eric Liu¹ and Andras Perl ², ¹SUNY Upstate University Medical Center, Syracuse, NY, ²SUNY Upstate Medical University, Syracuse, NY
Background/Purpose: Hydroxychloroquine (HCQ) is a commonly used medication in our field of work with retinal toxicity being a known possible long-term side effect of the…
Abstract Number: 2580 • 2019 ACR/ARP Annual Meeting
Pharmacotherapies Targeting Type 2 SLE Symptoms
Raeann Whitney¹, Amanda Eudy ¹, Megan Clowse ¹, Lisa Criscione-Schreiber ¹, Jayanth Doss ¹, David Pisetsky ², Kai Sun ¹, Rebecca Sadun ¹ and Jennifer Rogers ¹, ¹Duke University, Durham, ²Duke University, Durham VAMC, Durham
Background/Purpose: We propose categorizing lupus activity to better align with patient experience: Type 1 SLE activity includes classic symptoms such as arthritis and nephritis; Type…
Abstract Number: 2581 • 2019 ACR/ARP Annual Meeting
Clinical Impact of Decreasing Hydroxychloroquine Dose According to the 2016 American Academy of Ophthalmology Guidelines in Patients with Systemic Lupus Erythematosus
Nicolle Medina-Cintrón¹, Ileana Vázquez-Otero ¹, Mariangelí Arroyo-Ávila ¹, Lorena González-Sepúlveda ¹ and Luis Vilá ¹, ¹University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
Background/Purpose: Hydroxychloroquine (HCQ) is one of the main drugs used for the treatment of systemic lupus erythematosus (SLE). Nonetheless, HCQ-induced retinal toxicity remains a major…
Abstract Number: 2582 • 2019 ACR/ARP Annual Meeting
Incidence of Antimalarials-Induced Retinopathy in Inflammatory Rheumatic Diseases, Using OCT and Visual Field Test : A Systematic Review and Meta-analysis
Helene de Cagny¹, Jacques Morel ², Cécile Gaujoux-Viala ³, Bernard Combe ⁴ and Cédric Lukas ⁵, ¹University Hospital of Montpellier, Montpellier, France, ²CHU MONTPELLIER, MONTPELLIER, France, ³Nîmes University Hospital, Nîmes, France, ⁴CHU Montpellier, Montpellier University, Montpellier, France, ⁵Rheumatology department, CHU Montpellier, Univ Montpellier, Montpellier, France
Background/Purpose: Antimalarials (AM) are frequently used as first-line therapy in mild inflammatory diseases, because of a good benefit/risk ratio. Their most severe side effect is…
Abstract Number: 2583 • 2019 ACR/ARP Annual Meeting
Prevalence and Risk Factors of Herpes Zoster Reactivation in Patients with Biopsy Proven Lupus Nephritis Undergoing Immunosuppressive Therapies
Chi Chiu Mok¹, Kar Li Chan ², Sau Mei Tse ² and Ling Yin Ho ², ¹Department of Medicine, Tuen Mun Hospital, Hong Kong, China (People's Republic), ²Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose: To study the prevalence of Herpes Zoster (HZ) reactivation in patients with biopsy confirmed lupus nephritis (LN) undergoing immunosuppressive therapies.Methods: Patients who had biopsy…
Abstract Number: 2584 • 2019 ACR/ARP Annual Meeting
Management of Cutaneous Manifestations of Lupus Erythematosus: A Systematic Review
Jessica Fairley¹, Shereen Oon ², Amanda Saracino ³ and Mandana Nikpour ², ¹Monash University, Melbourne, Australia, ²St Vincent's Hospital, Melbourne; The University of Melbourne, Melbourne, Australia, ³University College London, London, United Kingdom
Background/Purpose: Cutaneous lupus erythematosus (CLE), occurring with or without systemic lupus erythematosus (SLE), is a group of inflammatory skin diseases that can be very debilitating,…
Abstract Number: 2585 • 2019 ACR/ARP Annual Meeting
A Comparison of Risk of Ovarian Failure Following Intravenous Cyclophosphamide Therapy in Juvenile versus Adult Systemic Lupus Erythematosus
shefali sharma¹, Hemanth Chinthala ², siddharth Jain ², Arghya Chattopadhyay ², Pooja Bahl ², Varun Dhir ³, naresh Sachdeva ² and Surjit Singh ⁴, ¹Dr., Chandigarh, Chandigarh, India, ²Post Graduate Institute of Medical Education and Research, chandigarh, Chandigarh, India, ³Post Graduate Institute of Medical Education and Research, Chandigarh, India, ⁴Allergy Immunology Unit, Department pf Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Background/Purpose: Premature ovarian failure is a dreaded complication of cyclophosphamide (CYC). It is related to age of initiation of therapy and the cumulative dose. This…
Abstract Number: 2586 • 2019 ACR/ARP Annual Meeting
Clinical Characteristics and Survival in Systemic Sclerosis-mixed Connective Tissue Disease and Systemic Sclerosis-overlap Syndrome
Jessica Fairley¹, Dylan Hansen ², Susanna Proudman ³, Joanne Sahhar ¹, Gene-Siew Ngian ¹, Jenny Walker ⁴, Gemma Strickland ², Michelle Wilson ², Kathleen Morrisroe ², Nava Ferdowski ², Gabor Major ⁵, Janet Roddy ⁶, Wendy Stevens ² and Mandana Nikpour ⁷, ¹Monash University, Melbourne, Australia, ²St Vincent's Hospital, Melbourne, Melbourne, Australia, ³University of Adelaide, Adelaide, Australia, ⁴Royal Adelaide Hospital, Melbourne, Australia, ⁵Royal Newcastle Centre John Hunter Hospital, Newcastle, Australia, ⁶Fiona Stanley Hospital, Perth, Australia, ⁷St Vincent's Hospital, Melbourne; The University of Melbourne, Melbourne, Australia
Background/Purpose: Mixed connective tissue disease (MCTD) is defined by presence of anti-RNP antibody together with 3 or more of swollen hands, synovitis, myositis, Raynaud phenomenon…
Abstract Number: 2587 • 2019 ACR/ARP Annual Meeting
Prognostic Role of Measurement of Renal Resistive Index in Systemic Sclerosis
shefali sharma¹, Arghya Chattopadhyay ², siddharth Jain ², Varun Dhir ³, mahesh Prakash ³ and manish Rathi ², ¹Dr., Chandigarh, Chandigarh, India, ²Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India, ³Post Graduate Institute of Medical Education and Research, Chandigarh, India
Background/Purpose: Spectrum of vascular involvement in systemic sclerosis (SSc) is diverse like Raynaud’s phenomenon, digital ulcers, pulmonary hypertension and renal disease. Recognition of markers of…
Abstract Number: 2588 • 2019 ACR/ARP Annual Meeting
Myositis-specific and -associated Antibodies in Systemic Sclerosis: Prevalence and Clinical Associations
Amélie Leurs ¹, Sylvain Dubucquoi ¹, François Machuron ¹, Maité Balden ¹, Florence Renaud ¹, Stéphanie Rogeau ¹, Benjamin Lopez ², Marc LAMBERT ³, Sandrine Morell-Dubois ⁴, Hélène Maillard ⁴, Hélène Behal ¹, Eric Hachulla ⁵, David Launay ¹ and Vincent Sobanski¹, ¹CHU Lille, Lille, France, ²Institute of Immunology, CHU Lille, University of Lille, Lille, France, ³Lille University Hospital, Lille, France, ⁴Department of Internal Medicine and Clinical Immunology, CHU Lille, University of Lille, Lille, France, ⁵Dept. of Internal Medicine and Clinical Immunology, Hôpital Claude Huriez, University of Lille, Lille, France, Lille, France
Background/Purpose: In systemic sclerosis (SSc) and idiopathic inflammatory myopathies (IIM), auto-antibodies are used in daily practice as potent biomarkers of clinical phenotypes. This study aimed…
Abstract Number: 2589 • 2019 ACR/ARP Annual Meeting
Searching the Calcinosis Signature: A Case Control Study Analyzing Limited Systemic Sclerosis Female Patients with and Without Calcinosis, Paired by Disease Duration, Age and Body Mass Index
Marilia Sampaio-Barros ¹, Lorena Castelo-Branco ¹, Liliam Takayama ¹, Marco Pontes-Filho ¹, Percival Degrava Sampaio-Barros ² and Rosa Pereira³, ¹University of Sao Paulo, Sao Paulo, Brazil, ²Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, Brazil, Sao Paulo, Brazil, ³Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil
Background/Purpose: Calcinosis usually represents a late manifestation of limited systemic sclerosis (lSSc), inducing chronic calcifications that lead to significant impairment in the quality of life.…
Abstract Number: 2590 • 2019 ACR/ARP Annual Meeting
Computer Vision Applied to Dual Energy Computed Tomography Images for Precise Calcinosis Cutis Quantification in Patients with Systemic Sclerosis
Anita Chandrasekaran¹, Imran Omar ², Zhicheng Fu ³, Shangping Ren ³ and Monique Hinchcliff ¹, ¹Yale University, Section of Rheumatology, Allergy and Immunology, New Haven, CT, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³San Diego State University, Department of Computer Science, San Diego, CA
Background/Purpose: Calcinosis cutis, found in both systemic sclerosis (SSc) and juvenile dermatomyositis patients, can be extensive and debilitating. Potential treatments have been identified, but a…
Abstract Number: 2591 • 2019 ACR/ARP Annual Meeting
Hospitalization Among Incident Cases of Systemic Sclerosis: Results from a Population-based Cohort (1980-2016)
Caitrin Coffey¹, Avneek Singh Sandhu ², Cynthia Crowson ³, Sara Achenbach ¹, Eric Matteson ⁴, Thomas Osborn ⁵, Kenneth Warrington ⁶ and Ashima Makol ⁵, ¹Mayo Clinic, Rochester, MN, ²kettering health, dayton, OH, ³Mayo Clinic Rochester, Rochester, ⁴Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, Rochester, ⁵Mayo Clinic Minnesota, rochester, MN, ⁶Mayo Clinic Rochester, Rochester, MN
Background/Purpose: Systemic sclerosis (SSc) is an autoimmune disorder associated with multi-organ dysfunction, requiring long-term and multi-disciplinary care. Few studies have estimated the healthcare resource usage…
Abstract Number: 2592 • 2019 ACR/ARP Annual Meeting
Longitudinal Changes in Health-related Quality of Life in Systemic Sclerosis Treated with Autologous Hematopoietic Stem Cell Transplant Compared to Standard of Care
Nancy Maltez¹, Mathieu Puyade ², Pauline Lansiaux ³, Mianbo Wang ⁴, Murray Baron ⁵, Ines Colmegna ⁶, Dominique Farge ⁷ and Marie Hudson ⁸, ¹The Ottawa Hospital, Ottawa, ²CHU de Poitiers Unité d'Hospitalisation d'Aval, Poitiers Cédex, France, ³Institut de Recherche Saint-Louis, Paris, France, ⁴Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada, ⁵Jewish General Hospital, McGill University, Montreal, Canada, ⁶McGill University Health Center, Montreal, QC, Canada, ⁷Hôpital Saint-Louis, AP-HP Assistance Publique des Hôpitaux de Paris, Centre de Référence des Maladies Auto-Immunes Systémiques Rares d’Ile-de-France, Filière ‘FAI2R’, Unité de Médecine Interne: Maladies Auto-immunes et Pathologie Vasculaire (UF 04), Université de Paris, EA 3518, Paris, France; Department of Medicine, McGill University, Montreal, QC, Canada, Paris, France, ⁸Jewish General Hospital, Lady Davis Institute for Medical Research, and Department of Medicine, McGill University, Montreal, QC, Canada
Background/Purpose: In severe, early progressive systemic sclerosis (SSc), autologous hematopoietic stem cell transplantation (AHSCT) allows significant improvements in overall and event free survival. The objectives…
Abstract Number: 2593 • 2019 ACR/ARP Annual Meeting
Cyclophosphamide for the Treatment of Skin Fibrosis in Systemic Sclerosis: A Systematic Review
Marie Hudson ¹, Nancy Maltez², Catherine Ivory ² and Melissa Demery-Varin ³, ¹Jewish General Hospital, Lady Davis Institute for Medical Research, and Department of Medicine, McGill University, Montreal, QC, Canada, ²The Ottawa Hospital, Ottawa, ³University of Ottawa, Ottawa
Background/Purpose: Systemic sclerosis (SSc) is a chronic disease characterized by multi-organ involvement. Excess collagen deposition and fibrosis is thought to result from a complex interplay…

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