Abstracts Archive - Page 1056 of 2425 - ACR Meeting Abstracts

Abstract Number: 771 • 2018 ACR/ARHP Annual Meeting
Does Cognitive Function Change over-Time in Systemic Lupus Erythematosus?
Zahi Touma¹, Robin Green², Carmela Tartaglia³, Lesley Ruttan⁴, Sabrina Lombardi⁵, Nicole Anderson⁶, Jiandong Su¹, Kenneth Colosimo⁴, Michelle Vitti¹, Joan E. Wither⁷, Marvin J. Fritzler⁸ and Dorcas Beaton⁹, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, ³University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁴Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁵Psychology & Neuropsychology Complex Injury, Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁶Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁷Department of Immunology, Department of Immunology, University of Toronto, Toronto, ON, Canada, ⁸Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁹Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Cognitive impairment (CI) is a common neurobehavioral manifestation of SLE. In our recent systematic review, the prevalence of CI was 38% (95% CI: 33-43%).…
Abstract Number: 772 • 2018 ACR/ARHP Annual Meeting
Cytomegaloviral or Pneumocystis Jiroveci Pneumonia Increases Mortality Rate in Systemic Lupus Erythematosus Patients with Pulmonary Hemorrhage: Evidence from Bronchoalveolar Lavage Fluid Analysis
Chien-Chih Lai, Yi-Syuan Sun and De-Feng Huang, Allergy, Immunology, Rheumatology, Taipei Veterans General Hospital, Taiwan, Taipei City, Taiwan
Background/Purpose: To evaluate the role of cytomegaloviral or Pneumocystic jiroveci pneumonia (CMV/PJP) in SLE patients with pulmonary hemorrhage (PH).Methods: We retrospectively examined hospital records for…
Abstract Number: 773 • 2018 ACR/ARHP Annual Meeting
Exploring the Relation between Immunoglobulins Level and Infection Risk in Adult Patients with Systemic Lupus Erythematosus
Ibrahim Almaghlouth^1,2, Jiandong Su³, Eleanor Pullenayegum⁴, Sindhu Johnson⁵, Dafna D Gladman³ and Murray Urowitz⁶, ¹Division of Rheumatology, Department of medicine, King Saud University, King Khalid University Hospital, Riyadh, Saudi Arabia, ²Division of Rheumatology, Department of medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada, ⁵Rheumatology, Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, ⁶Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Infection is a major cause of mortality in all stages of disease in systemic lupus erythematosus (SLE). Several risk factors for infection have been…
Abstract Number: 774 • 2018 ACR/ARHP Annual Meeting
Clinical Variables and Serologic Markers of Disease Activity Do Not Aid in Early Recognition of Patients with Tubulointerstitial Disease Who Have No Significant Renal Impairment at Time of Biopsy
Alejandra Londono Jimenez¹, Beatrice Goilav², Maria Salgado Guerrero³, Kimberly A. Lynch⁴, Wenzhu B. Mowrey² and Anna R. Broder⁵, ¹Rheumatology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Internal Medicine, Jacobi Medical Center, Bronx, NY, ⁴Internal Medicine, Montefiore Medical Center, Bronx, NY, ⁵Rheumatology-Forchheimer 701N, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY
Background/Purpose: Tubulointerstitial damage (TID), defined as tubulointerstitial inflammation (TII) or interstitial fibrosis/tubular atrophy/ (IF/TA) is associated with poor renal outcomes in lupus nephritis (LN)1. Glomerular…
Abstract Number: 775 • 2018 ACR/ARHP Annual Meeting
Endomyocardial Biopsies in the Diagnosis of Myocardial Involvement in Systemic Lupus Erythematosus
Laura Geraldino-Pardilla¹, Teja Kapoor², Thania Perez³ and Anca Askanase³, ¹Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Myocardial dysfunction is reported in over half of systemic lupus erythematosus (SLE) patients, yet the underlying pathogenesis remains poorly understood. Endomyocardial biopsies (EMBs) are…
Abstract Number: 776 • 2018 ACR/ARHP Annual Meeting
MMP7 and CXCL12: Two Promising Biomarkers in Lupus Nephritis
Sylvie Goletti^1,2, Séverine Nieuwland³, Frédéric A. Houssiau^2,3 and Bernard R. Lauwerys^2,3, ¹Service de Microbiologie, Cliniques Universitaires Saint-Luc, Brussels, Belgium, ²Pôle de pathologies rhumatismales systémiques et inflammatoires, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium, ³Rheumatology Department, Cliniques universitaires Saint-Luc, Brussels, Belgium
Background/Purpose: Lupus nephritis (LN) is one of the most serious complications of Systemic lupus erythematosus (SLE). Early diagnosis of renal impairment, combined with a strict…
Abstract Number: 777 • 2018 ACR/ARHP Annual Meeting
Electrocardiographic Abnormalities Are Associated with the Occurrence of Strokes in Systemic Lupus Erythematosus
Thania Perez¹, Christopher Depender², Jianhua Li³ and Laura Geraldino-Pardilla⁴, ¹Columbia University, College of Physicians & Surgeons, New York, NY, ²Medicine/Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, ⁴Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Electrocardiographic Abnormalities Are Associated with the Occurrence of Strokes in Systemic Lupus Erythematosus Background/Purpose: Systemic lupus erythematosus (SLE) patients have a 10-fold higher risk for…
Abstract Number: 778 • 2018 ACR/ARHP Annual Meeting
Rates of Herpes Zoster Virus Infection in SLE Patients on Immunosuppression
Inessa Gendlina¹, Alejandra Londono Jimenez², Kimberly A. Lynch², Wenzhu B. Mowrey³, Yevgeniy Balagula⁴ and Anna R. Broder⁵, ¹Infectious Disease, Albert Einstein College of Medicine, Bronx, NY, ²Internal Medicine, Montefiore Medical Center, Bronx, NY, ³Albert Einstein College of Medicine, Bronx, NY, ⁴Medicine/Dermatology, Montefiore Medical Systems, Bronx, NY, ⁵Rheumatology-Forchheimer 701N, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY
Background/Purpose: Increased incidence of herpes zoster (HZ) has been reported in patients with autoimmune diseases. SLE in particular is known to be associated with a…
Abstract Number: 779 • 2018 ACR/ARHP Annual Meeting
Cerebrospinal Fluid Biomarkers for Diagnosing Neuropsychiatric SLE: A Systematic Review and Meta-Analysis
Seyed-Foad Ahmadi¹, Golara Zahmatkesh², Masoud Majed³ and Sheetal Desai⁴, ¹Department of Medicine, University of California Irvine, Orange, CA, ²Department of Psychiatry, University of New Mexico, Albuquerque, NM, ³Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Medicine/Rheumatology, Unviersity of California, Irvine, Orange, CA
Cerebrospinal Fluid Biomarkers for Diagnosing Neuropsychiatric SLE: A Systematic Review and Meta-analysis Background/Purpose: Current guidelines recommend that in suspected neuropsychiatric SLE (NPSLE), the initial diagnostic workup…
Abstract Number: 780 • 2018 ACR/ARHP Annual Meeting
Urine Metabolomic Profile in Lupus Nephritis
David Herrera Van Oostdam¹, Carlos Abud-Mendoza², Maribel Rodriguez Aguilar³, Rogelio Flores Ramirez³, Mauricio Pierdant Pérez⁴, Cesar Eduardo Vallín Orozco⁵ and Marco Ulises Martinez-Martinez⁶, ¹Unidad de Investigaciones Reumatológicas, Hospital Central & Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, ²Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosi, S.L.P., Mexico, ³2. Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología, San Luis Potosí, San Luis Potosi, Mexico, ⁴Universidad Autónoma de San Luis Potosí, San Luis Potosi, Mexico, ⁵Rheumatology, Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí, Mexico, ⁶Unidad de Investigaciones Reumatológicas, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico
Background/Purpose: Lupus nephritis (LN) develops in 50-60% of lupus patients. The consequence of this entity is renal failure, that can arise in 10-15% of patients…
Abstract Number: 781 • 2018 ACR/ARHP Annual Meeting
Simultaneous Identification of Two Biomarkers in ACTIVE LUPUS Nephritis: Autophagy in Treg CELLS and Prolactin Receptors in B Lymphocytes
Luis J. Jara-Quezada¹, Emma Zurita², Ana Durán², Antonio Sanchez³, Reyna Bustamante³, Gabriela Medina⁴, Miguel A Saavedra⁵, María Pilar Cruz-Dominguez³, Olga Vera-Lastra⁶, María Pilar Jiménez-Arellano⁷, Michel Augusto Martínez-Bencomo³ and Azucena Rodriguez², ¹Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,, Mexico, Mexico, ²Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,, Mexico City, Mexico, ³Hospital de Especialidades "Dr. Antonio Fraga Mouret", Centro Médico Nacional "La Raza", Mexico City, Mexico, ⁴Clinical Research Unit, Hospital de Especialidades Centro Medico La Raza,IMSS, Mexico City, Mexico, ⁵Novartis Farmaceutica, Calz de Tlaplan 1779, Mexico, Mexico, ⁶Rheumatology, Instituto Mexicano Seguro Social, Mexico City, Mexico, ⁷Hospital de Especialidades "Dr. Antonio Fraga Mouret", Centro Médico Nacional "La Raza", Mexico CIty, Mexico
Background/Purpose: Recent studies suggest that autophagy defects contributes to systemic lupus erythematosus (SLE) pathogenesis. Prolactin (PRL) is associated with active SLE and stimulates the immune…
Abstract Number: 782 • 2018 ACR/ARHP Annual Meeting
Cognitive Impairment and Health-Related Quality of Life in a Lupus Cohort
Chrisanna Dobrowolski¹, Lisa Engel², Robin Green³, Lesley Ruttan⁴, Sabrina Lombardi⁴, Carmela Tartaglia⁵, Nicole Anderson², Kenneth Colosimo², Michelle Vitti², Dennisse Bonilla², Joan E. Wither⁶, Marvin J. Fritzler⁷, Dorcas Beaton⁸ and Zahi Touma², ¹University of Ottawa, Ottawa, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁴Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁵University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁶Genetics and Development, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁷Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁸Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Patients with systemic lupus erythematosus (SLE) are commonly affected by cognitive impairment (CI), with a meta-analysis finding a prevalence of 38%. Despite this high…
Abstract Number: 783 • 2018 ACR/ARHP Annual Meeting
Procalcitonin and CXCL9 As Potential Biomarkers for Pneumonia in Patients with Systemic Lupus Erythematosus
Hilda Fragoso-Loyo¹, Andrea Hinojosa-Azaola¹, Ricardo Ríos-Corzo², John Hernandez-Flores³, Mariana Lopez-Lopez¹, Ariadna Díaz-Mora¹, Alma Lilia Pulido-Ramírez², Jose Sifuentes-Osornio³, María de Lourdes Guerrero-Almeida⁴, Luis Alfredo Ponce de León-Garduño⁴, Eduardo Carrillo-Maravilla⁵, Luis Llorente¹ and Yemil Atisha-Fregoso^6,7, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Medicine Division, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ³Internal Medicine, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁴Infectious Diseases Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Medicina Interna, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico, ⁶Instituto Tecnológico de Estudios Superiores de Monterrey, Mexico City, Mexico, ⁷Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
Background/Purpose: Pneumonia is an important cause of death in patients with SLE. In general population, recommendations encourage the use of procalcitonin for management of pneumonia,…
Abstract Number: 784 • 2018 ACR/ARHP Annual Meeting
Prediction of Hospital-Acquired Bacterial Infections in Patients with SLE
Pablo Castaño-Gonzalez¹, Mauricio Restrepo-Escobar^1,2, Laura Morales-Maya¹, Tomás Urrego¹, Simon Sandoval-Alvares¹, Carlos Horacio Muñoz^1,3, Adriana L Vanegas^1,3, Daniel Jaramillo^1,4, Gloria Vasquez¹ and Luis Gonzalez-Naranjo¹, ¹Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universidad de Antioquia, Medellin, Colombia, ²Hospital Universitario Pablo Tobon Uribe, Medellin, Colombia, ³Hospital Universitario de San Vicente Fundación, Medellín, Colombia, ⁴Hospital Universitario de San Vicente Fundación, Medellin, Colombia
Background/Purpose: Patients with SLE have an increased risk of serious infections, including nosocomial infections, which are associated with potentially modifiable adverse outcomes. Our objective is…
Abstract Number: 785 • 2018 ACR/ARHP Annual Meeting
Correlation between Nailfold Capillary Number and Blood Perfusion in Systemic Lupus Erythematosus Patients
Alberto Sulli¹, Barbara Ruaro¹, Carmen Pizzorni¹, Vanessa Smith², Sabrina Paolino³, Veronica Tomatis¹, Monica Pendolino¹ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ²Department of Internal Medicine, Department of Rheumatology, Ghent University Hospital, Department of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, ³Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy
Background/Purpose: Numerous articles have investigated peripheral microcirculation in primary Raynaud’s phenomenon (RP) (1,2). Reports evaluating peripheral microcirculation in systemic lupus erythematosus (SLE) are scanty, but…

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