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  • Abstract Number: 1363 • 2019 ACR/ARP Annual Meeting

    Longitudinal Work Transitions in Early Inflammatory Arthritis Patients: Are There Targets for Intervention to Improve Employment?

    Lily SH Lim1, Doris Cheung 1, Kaviul Mohamed 2, Diane Lacaille 3, Eleanor M. Pullenayegum 4 and Carol Hitchon 1, 1University of Manitoba, Winnipeg, MB, Canada, 2University of Toronto, Toronto, ON, Canada, 3Arthritis Research Canada and University of British Columbia, Vancouver, BC, Canada, 4Child Health Evaluative Sciences, The Hospital for Sick Children, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

    Background/Purpose: Historically, increasing proportions of patients with rheumatoid arthritis stop working on long-term follow-up, often due to arthritis. The trajectory of work transitions in early…
  • Abstract Number: 1364 • 2019 ACR/ARP Annual Meeting

    Affect of Obesity on Multi-Biomarker Disease Activity (MBDA) Measurements in Rheumatoid Arthritis (RA) Patients

    Yael Ross1, Madhavi Siddhanthi 2, Lewis VanBrackle 3, David Carpenter 4, Aishwarya Rallabhandy 5 and Mohammad Kamran 2, 1WellStar Kennestone regional medical center, Atlanta, GA, 2WellStar Medical Group, Marietta, GA, 3Kennesaw State University, Kennesaw, 4WellStar Kennestone regional medical center, Marietta, 5High School, Marietta

    Background/Purpose: The goal for treatment of RA is to obtain low disease activity for better outcomes. In order to achieve low disease activity, it is…
  • Abstract Number: 1365 • 2019 ACR/ARP Annual Meeting

    Construct Validation of PROMIS Short Form and Profile-29 T-Scores with SF-36 in Rheumatoid Arthritis Patients Treated for 1 Year: Results from a Real World Evidence-Based Study in the United States

    Clifton Bingham1, Shelly Kafka 2, Shawn Black 3, Stephen Xu 4 and Jeffrey Curtis 5, 1Johns Hopkins University, Baltimore, MD, 2Janssen Scientific Affairs, LLC, Horsham, PA, 3Janssen Scientific Affairs, LLC, Horsham, RI, 4Janssen Research & Development, LLC, Spring House, PA, 5University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Use of PROs to assess health-related quality of life in clinical practice, research studies, and clinical trials in Rheumatoid Arthritis (RA) remains an ongoing…
  • Abstract Number: 1366 • 2019 ACR/ARP Annual Meeting

    Self-joint Counts by People with Rheumatoid Arthritis: Does a Video Increase Accuracy and Does It Matter?

    Rebecca Grainger1, Simon Stebbings 2, William Taylor 1, Andrew Harrison 1, Celina Capistrano 1, Niamh Fanning 3 and Lisa Stamp 4, 1University of Otago, Wellington, New Zealand, 2University of Otago, Dunedin, New Zealand, 3University of Otago, Christchurch, Christchurch, New Zealand, 4University of Otago, Christchurch, New Zealand

    Background/Purpose: As a tool for self-monitoring and reporting RA disease activity, a smartphone app was developed to enable people with rheumatoid arthritis (RA) to record…
  • Abstract Number: 1367 • 2019 ACR/ARP Annual Meeting

    An Engineered Glove for the Computerised Quantification of Hand Disability in Rheumatoid Arthritis

    Massimo Patane' 1, Luca Carmisciano 2, Emanuele Gotelli 3, Veronica Tomatis 4, Francesco Cattelan 5, Elisa Alessandri 6, Alessio Signori 2, Massimo Ghio 7, Vanessa Smith 8 and Maurizio Cutolo9, 1Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, 2Biostatistics Unit, Department of Health Sciences, University of Genoa, Genoa, Italy, 3Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Genoa, Italy, 4Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genova, Italy, Genoa, Italy, 5Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS Polyclinic Hospital San Martino, University of Genoa, Genoa, Italy, 6Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genoa, Italy, Genova, 7Research Laboratory and Academic Division of the Clinical Rheumatology Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, 8Department of Rheumatology, Ghent University Hospital; Department of Internal Medicine, Ghent University; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium, 9Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, Genoa, Italy

    Background/Purpose: Background Rheumatoid arthritis (RA) is a long-term, progressive, and disabling autoimmune disease. The disease activity can be quantified by the Disease Activity Score 28-joint count…
  • Abstract Number: 1368 • 2019 ACR/ARP Annual Meeting

    One Size Fits All : Replacing ESR by γGT in DAS28 Calculation Permits a Dual Evaluation of Joint Activity Together with Cardiovascular Risk

    Hélène Vergneault 1, Eloïse Vandebeuque 2, Veronica Codullo 1, Yannick Allanore 3 and Jérôme Avouac1, 1Cochin Hospital, Paris, France, 2Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, 3Dept. of Rheumatology A, Descartes University, APHP, Cochin Hospital, Paris, France, Paris, France

    Background/Purpose: Patients with rheumatoid arthritis (RA) experience premature mortality that is largely due to cardiovascular disease (CVD). Ample evidence suggests that elevated γGT activity is…
  • Abstract Number: 1369 • 2019 ACR/ARP Annual Meeting

    Angiogenic Factors for Assessing Rheumatoid Arthritis in the Era of Sonographic Diagnosis and Biologic Therapy

    Ji-Won Kim1, Jin-Sun Kong 2, Youngjae Park 3 and Wan-Uk Kim 3, 1Catholic University of Daegu School of Medicine, Daegu, Republic of Korea, 2Catholic University of Korea, College of Medicine, Seoul, Republic of Korea, 3Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

    Background/Purpose: Previously, we demonstrated the direct pro-inflammatory role of the vascular endothelial growth factor (VEGF) and the placenta growth factor (PlGF), and angiogenic factors in…
  • Abstract Number: 1370 • 2019 ACR/ARP Annual Meeting

    Not All Joints Are Equal: Challenge DAS28 System and Identify Factors Leading to a Mismatch Between T2T and HAQ Among RA Patients Through Data Mining from Smart System of Disease Management (SSDM)

    Jing Yang1, Zhenbiao Wu 2, Yongfu Wang 3, Hua Wei 4, Yu Zhang 1, Xiaoling Liu 5, Xiaofeng Rong 6, Jinmei Zou 1, Xiaofei Shi 7, Hongbin Li 8, Rui Wu 9, Xiaoli Deng 10, Huiqiong Zhou 11, Yuan Jia 12, Wei Zhao 13, Shi Chen 12, Xuewu Zhang 12, Yingnan Li 14, Yingkun Nie 14, Yifang Mei 15, Jianyu Zhang 16, Hanyou Mo 17, li Sun 18, Yanfei Chen 19, Haili Shen 20, Dongsheng Li 21, Yonggang Zhao 22, Hui Xiao 23, Bing Wu 24, Yuhua Jia 22 and Fei Xiao 25, 1Central Hospital of MianYang, Mianyang, Sichuan, China (People's Republic), 2The First Affiliated Hospital of The Fourth Military Medical University, Xian, Shanxi, China (People's Republic), 3The First Affiliated Hospital of BaoTou Medical College, Baotou, Nei Mongol, China (People's Republic), 4Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 5The 1st Affiliated Hospital of Guangzhou University of TCM, Guangzhou, China (People's Republic), 6The 1st Affiliated hospital of Chongqing medical University, Chongqing, Chongqing, China (People's Republic), 7First Affiliated Hospital of Henan University of Science and Technology, luoyang, Henan, China (People's Republic), 8The Affiliated Hospital of Inner Mongolia Medical University, Huhhot, Nei Mongol, China (People's Republic), 9The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China (People's Republic), 10Peking University Third Hospital, Beijing, Beijing, China (People's Republic), 11Fourth Medical Center of PLA Genal Hospital, Beijing, Beijing, China (People's Republic), 12Peking University People's Hospital, Beijing, Beijing, China (People's Republic), 13Chinese PLA General Hospital, Beijing, Beijing, China (People's Republic), 14The 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China (People's Republic), 15The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China (People's Republic), 16The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China (People's Republic), 17Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China (People's Republic), 18The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China (People's Republic), 19The First Hospital of Lanzhou University, Lanzhou, Gansu, China (People's Republic), 20The Second Hospital of Lanzhou University, Lanzhou, Gansu, China (People's Republic), 21Ganzhou People's Hospital, Ganzhou, Jiangxi, China (People's Republic), 22Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 23Shanghai Gothic Internet Technology Co., Ltd, shanghai, Shanghai, China (People's Republic), 24Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), 25Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic)

    Background/Purpose: Treat to target (T2T), achieving a DAS28 score lower than 3.2, is the strategy recommended by ACR and EULAR. Health assessment questionnaire (HAQ) is…
  • Abstract Number: 1371 • 2019 ACR/ARP Annual Meeting

    Create an Algorithm of Outcome Forecasting and Decision Making for RA Treatment: Data Mining and Machine Learning via the Smart System of Disease Management (SSDM)

    Rong Mu1, Chun Li 2, Jing Yang 3, Xiaohan Wang 4, Bin Wu 5, Fengxiao Zhang 6, Yong Wang 7, Li Qin 8, Cundong Mi 9, Huifang Guo 10, Wei Wei 11, Wei Liu 12, Qingchun Huang 13, Jing Lu 14, Yang Liu 15, Huiling Li 16, Bing Wu 17, Hui Xiao 18, Yuhua Jia 19 and Fei Xiao 20, 1People's Hospital, Beijing University Medical School, Beijing, China (People's Republic), 2People's Hospital, Beijing University Medical School, Beijing, Beijing, China (People's Republic), 3Central Hospital of MianYang, Mianyang, Sichuan, China (People's Republic), 4Anyang district hospital, Fuyang, Hainan, China (People's Republic), 5Chongqing Hospital of Traditional Chinese Medicine, Chongqing, Chongqing, China (People's Republic), 6Hebei General Hospital, Shijiazhuang, Hebei, China (People's Republic), 7The first Hospital Affiliated to AMU (Southernwest Hospital), Chongqing, China (People's Republic), 8The No.3 People’s Hospital of HuZhou City, Huzhou, Zhejiang, China (People's Republic), 9The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China (People's Republic), 10The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China (People's Republic), 11Tianjin Medical University General Hospital, Tianjin, Tianjin, China (People's Republic), 12First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China (People's Republic), 13The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China (People's Republic), 14First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China (People's Republic), 15Affiliated Hospital of Inner Mongolia Medical University, Huhehaote, Nei Mongol, China (People's Republic), 16Hubei Hospital of Traditional Chinese Medicine, Wuhan, Hubei, China (People's Republic), 17Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), 18Shanghai Gothic Internet Technology Co., Ltd, shanghai, Shanghai, China (People's Republic), 19Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 20Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic)

    Background/Purpose: Daily health care deals with a wide spectrum of RA patients from statuses of remission (R) to disease activities at low (L), moderate (M)…
  • Abstract Number: 1372 • 2019 ACR/ARP Annual Meeting

    Adherence to Treatment with Intravenous Biological Agents in Patients with Rheumatoid Arthritis

    Gisele Alejandra Luna1, fernando dal Pra 2, Emilce Schneeberger 3, Leonela Lysseth Macias Oviedo 4 and Gustavo Citera 5, 1Instituto de Rehabilitación Psicofísica, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 2Instituto Rehabilitacion Psicofisica, CABA, Ciudad Autonoma de Buenos Aires, Argentina, 3Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Instituto de Rehabilitacion Psicofisica, CABA, Ciudad Autonoma de Buenos Aires, Argentina, 5Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: The adherence to the therapeutic regimen in patients with Rheumatoid Arthritis (RA) varies between 30 and 80%. Classically, it is mentioned that the adherence…
  • Abstract Number: 1373 • 2019 ACR/ARP Annual Meeting

    Performance of CQR5 vs CQR19 in the Evaluation of Adherence to Tofacitinib in Daily Clinical Practice

    Tatiana Barbich1, Osvaldo Luis Cerda 2, Emilce Schneeberger 3 and Gustavo Citera 4, 1Instituto de Rehabilitación Psicofísica, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 2Instituto de Rehabilitacion Psicofisica, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 3Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: To evaluate the adherence to treatment with Tofacitinib in patients with Rheumatoid Arthritis (RA) using both versions of the self-questionnaire Compliance Questionnaire Rheumatology: CQR19…
  • Abstract Number: 1374 • 2019 ACR/ARP Annual Meeting

    Real-World Evidence: Infections Among RA Patients Switching from First Biologic DMARD to Another Treatment in the US

    Robin Dore1, Jenya Antonova 2, Huan Huang 3, Lawrence Chang 2, Xin Wang 3 and Mark Genovese 4, 1Private practice, Tustin, CA, 2Gilead Sciences, Foster City, CA, 3IQVIA, Plymouth Meeting, PA, 4Stanford University, Stanford, CA

    Background/Purpose: Infections are common safety events monitored in RA patients.1 ACR guidelines limit the use of live vaccines in patients who are on biologic (b)DMARDs…
  • Abstract Number: 1375 • 2019 ACR/ARP Annual Meeting

    Patient-Reported Outcomes of Upadacitinib versus Adalimumab Use in Patients with Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate: 26-Week Analysis of a Phase 3 Study

    Roy Fleischmann1, Martin Bergman 2, Namita Tundia 3, In-Ho Song 4, Jessica Suboticki 4, Yan Song 5 and Vibeke Strand 6, 1Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 2Drexel University College of Medicine, Stockholm, Sweden, 3AbbVie Inc., North Chicago, IL, 4AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, 5Analysis Group, Inc., Boston, MA, 6Division of Immunology/Rheumatology, Stanford University, Stanford, CA

    Background/Purpose: In patients with active rheumatoid arthritis (RA), 12-week treatment with upadacitinib (UPA) while on background MTX therapy resulted in significant and clinically meaningful improvements…
  • Abstract Number: 1376 • 2019 ACR/ARP Annual Meeting

    Impact of 24- or 26-Week Upadacitinib Monotherapy on Patient-Reported Outcomes in Patients with Moderately to Severely Active Rheumatoid Arthritis and No Prior Use of or an Inadequate Response to Methotrexate: Results from Two Phase 3 Trials

    Vibeke Strand1, Namita Tundia 2, Alan Friedman 3, Heidi Camp 2, Jessica Suboticki 4, Debbie Goldschmidt 5, Catherine Fernan 5 and Martin Bergman 6, 1Division of Immunology/Rheumatology, Stanford University, Stanford, CA, 2AbbVie Inc., North Chicago, IL, 3AbbVie Inc., North Chicago, 4AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, 5Analysis Group, Inc., New York, NY, 6Drexel University College of Medicine, Stockholm, Sweden

    Background/Purpose: Treatment with upadacitinib (UPA) monotherapy, a selective Janus kinase-1 (JAK-1) inhibitor, resulted in significant and clinically meaningful improvements in patient-reported outcomes (PROs) at Week…
  • Abstract Number: 1377 • 2019 ACR/ARP Annual Meeting

    MTX Withdrawal in Patients with RA Who Achieve Low Disease Activity with Tofacitinib Modified-Release 11 Mg Once Daily + MTX: An Assessment of the Impact on the Short Form-36 Patient-Reported Outcome

    Vibeke Strand1, Janet Pope 2, John Woolcott 3, Jose L. Rivas 4, Annette Diehl 3, Shixue Liu 5, David Gruben 6 and Stanley Cohen 7, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2Western University, London, ON, Canada, 3Pfizer Inc, Collegeville, PA, 4Pfizer SLU, Madrid, Spain, 5Pfizer Inc, Shanghai, China (People's Republic), 6Pfizer Inc, Groton, CT, 7Metroplex Clinical Research Center, Dallas, TX

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. Tofacitinib +/- background MTX has been shown to be an effective treatment…
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