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Abstract Number: 2135

Musculoskeletal Pain Explains Differences In Function At Time Of Surgery In Black TKR and THR Patients

Anthony Porter1, Wenjun Li2, Leslie R. Harrold1, Milagros Rosal3, Philip Noble4, David Ayers2, Patricia D. Franklin2 and Jeroan Allison5, 1University of Massachusetts Medical School, Worcester, MA, 2Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, 3Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, MA, 4Baylor College of Medicine, Houston, TX, 5Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA

Meeting: 2013 ACR/ARHP Annual Meeting

Keywords: Osteoarthritis, Outcome measures, race/ethnicity and total joint replacement

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Session Information

Title: Osteoarthritis - Clinical Aspects II: Symptoms and Therapeutics in Osteoarthritis.

Session Type: Abstract Submissions (ACR)

Background/Purpose: The existence of racial disparities in total knee (TKR) and total hip (THR) replacement outcomes is well established but not well understood.  The burden of musculoskeletal co-morbidities was investigated among black and white TKR and THR patients at the time of surgery to assess whether that explains disparities in a prospective cohort.

Methods: Descriptive analyses were performed on a cohort  of 3,306 TKR and 2,439 THR patients. Data collected include sociodemographics (age, gender, race), body mass index (BMI), modified Charlson co-morbidity scores, operative joint pain severity using the Knee Injury/Hip Disability and Osteoarthritis Outcome Scores (KOOS/HOOS,), function based on the Short Form 36 (SF-36) Physical Component Score (PCS), emotional health using the SF-36 Mental Component Score (MCS), and musculoskeletal co-morbidity using the KOOS/HOOS (number of nonoperative hip and knee joints with moderate to severe pain; range 0-3) and Oswestry Disability Index (ODI). Factors associated with pre-operative pain and function were examined using multivariable stepwise linear regression models.

Results: At time of surgery, black TKR patients were significantly younger (62.0 vs. 66.9 years old), female (69.7% vs. 60.8%), heavier (34.6 vs. 31.3 BMI), exhibited higher prevalence of 2-5 medical co-morbidities (17.0% vs. 9.2%), poorer emotional health (47.4 vs. 52.1), poorer surgical knee pain (43.4 vs. 53.2), poorer function (31.3 vs. 33.1), and more pain in other weight-bearing joints than whites (p<0.02).  In regression models, after adjusting for these independent variables, race did not explain the differences in surgical knee pain and function at time of surgery (-4.3-0.8 p>0.05), while moderate to severe pain in up to three lower extremity joints had a significant effect (-23.4-[-15.9], p<0.0001).

At time of surgery, black THR patients were significantly younger (59.9 vs. 64.7 years old), heavier (31.7 vs. 29.1 BMI), exhibited higher prevalence of 2-5 medical co-morbidities (14.1% vs. 6.9%), poorer emotional health (47.0 vs. 50.9), greater surgical hip pain (39.3 vs. 49.2), poorer function (30.0 vs. 31.6), and more pain in other weight-bearing joints than whites (p<0.04).  In regression models, after adjusting for these independent variables, race did not explain the differences in surgical hip pain and function at time of surgery (-3.1-3.3, p>0.05), while moderate to severe pain in up to three lower extremity joints had a significant effect (-19.9-(-11.9), p<0.0001).

Conclusion: Black patients exhibit poorer function at the time of surgery compared to whites.  This difference was influenced by a greater burden of musculoskeletal pain in the large weight-bering joints in the legs. Racial disparities have been well established in previous studies. In this sample, musculoskeletal co-morbid pain was found to explain much of the poorer pre-operative function seen in black patients.


Disclosure:

A. Porter,
None;

W. Li,

AHRQ,

2;

L. R. Harrold,

CORRONA, Inc.,

5;

M. Rosal,

NIH/NIAMS,

2;

P. Noble,

Zimmer, Omni Sciences Inc., DePuy, J+J,

5;

D. Ayers,

AHRQ, Zimmer,

2;

P. D. Franklin,

NIAMS-NIH, NLM-NIH, AHRQ, Zimmer, ,

2;

J. Allison,

AHRQ,

2.

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