Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: Adherence to disease modifying anti-rheumatic drug (DMARD) therapy is suboptimal in patients with rheumatoid arthritis (RA). Efficient, low-cost measures are required for optimal monitoring of medication adherence in the rheumatology clinic. Self-report tools are the most efficient and cost-effective measures available. Recently, a 5-item version of the Compliance Questionnaire Rheumatology (CQR5) was developed from the original 19-item version and was validated in a group of RA patients
Methods: RA patients (disease duration ≥ 1 yr) taking at least one DMARD prescription were randomly selected from a rheumatology outpatient clinic database. Patients were assessed at baseline and three months. At each visit, medication adherence was assessed with the CQR5. Each item on the CQR5 was scored on a four point Likert scale (1 = strongly disagree, 4 = strongly agree). Scores for each item were then summed into a total score which varied between 0 and 20. Higher scores indicated greater adherence. Medication Beliefs were evaluated using the Beliefs about Medicines Questionnaire (BMQ)
Results: 100 RA patients, [age, mean (SD) = 60.75(12.67) yrs], were recruited and 10 dropped out of the study by three months. In this sample (n=90), the CQR5 demonstrated good test-retest reliability (ICC=0.73, 95% confidence interval = 0.61-0.81; Cronbach’s α = 0.84). At 3 months, adherence measured by CQR5 also had a significant positive correlation with BMQ necessity scores (r = 0.67, p<0.01) and significant negative correlations with BMQ concerns (r = -0.24, p<0.05), harm (r = -0.39, p<0.01), and overuse (r = -0.44, p<0.01) scores.
Conclusion: The CQR5 demonstrates long-term stability by maintaining its reliability and ability to predict medication beliefs over time. A more in-depth investigation of the predictive validity of the CQR5 using multiple chain imputation and multivariate analysis is currently underway.
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To cite this abstract in AMA style:Sweezie R, Bell M, Goldsmith CH, Chiu I, Gutlin A, Sandhu S. Long-Term Stability of the 5-Item Compliance Questionnaire Rheumatology As a Measure of Adherence in Patients with Rheumatoid Arthritis [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/long-term-stability-of-the-5-item-compliance-questionnaire-rheumatology-as-a-measure-of-adherence-in-patients-with-rheumatoid-arthritis/. Accessed February 28, 2020.
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