ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 1295

Disease Activity and Mental Health in SLE Patients: A Cross-section Study with Self-Assessments Based on Smart System of Disease Management (SSDM) Mobile Tools

Yongfu Wang1, Hua Wei2, Rui Wu3, Jianhong Wu4, Shengtao Zhang5, Qin Li6, Yang Li7, You Sun7, Yanping Zhao8, Qiang Shu9, Lirong Kang1, Bin Wu10, Li Qin11, Feng Jiang11, Huiqin Yang12, Junli Zhang13, Hui Xiao14, Bing Wu15, Yuhua Jia15, Fei Xiao15 and Lingyun Sun16, 1The First Affiliated Hospital of BaoTou Medical College, Inner Mongolia University of Science and Technology, Baotou, China (People's Republic), 2Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 3The First Affiliated Hospital of Nanchang University, Nanchang, China (People's Republic), 4Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 5Tongji Hospital Affiliated Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China (People's Republic), 6The First People's Hospital of Yunnan Province, Kunming, China (People's Republic), 7The Second Affiliated Hospital of Harbin Medical University, Harbin, China (People's Republic), 8First Affiliated Hospital of Harbin Medical University, Harbin, China (People's Republic), 9Qilu Hospital of Shandong University, Jinan, China (People's Republic), 10The First People's Hospital of Jingzhou, Jingzhou, China (People's Republic), 11The No.3 People’s Hospital of HuZhou City, Huzhou, China (People's Republic), 12Wuhan No. 1 Hospital, Wuhan, China (People's Republic), 13Xi'an No. 5 Hospital, Xi'an, China (People's Republic), 14Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 15Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 16Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China (People's Republic)

Meeting: ACR Convergence 2020

Keywords: Anxiety, depression, Disease Activity, mental health, Systemic lupus erythematosus (SLE)

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Date: Sunday, November 8, 2020

Title: SLE – Diagnosis, Manifestations, & Outcomes Poster II: Comorbidities

Session Type: Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose: WHO survey showed that the prevalence of anxiety and depression in Chinese population and Chinese patients with chronic diseases were between 3.1% – 4.2% and 3.1% – 7.3%, respectively. SLEDAI-2K and Hospital Anxiety and Depression Scale (HADS) are commonly used to evaluate SLE patients’ disease activity and mental health. All the Assessments were mainly performed by health professionals (HCPs) with paper questionnaire previously. SSDM is a novel smart disease management tool that allows patients to do self-assessments on SLEDAI-2K and HADS by mobile App.The purpose of this study is to investigate the prevalence of anxiety and depression in Chinese patients with SLE and to analyze the potential association between disease activity of SLE and mental health.

Methods: Under the guidance and training by HCPs, SLE patients downloaded SSDM and performed self-assessments bundle of SLEDAI-2K and HADS with SSDM. SLEDAI-2K < =4, 5-9, 10-14 and >=15 are defined SLE inactive, low (LDA), moderate (MDA) and high (HDA) disease activity, respectively. SLEDAI-2K score < = 4 is set as the main criteria for Lupus Low Disease Activity State (LLDAS) and achievement of T2T. HADS score >=8 can be diagnosed with anxiety or depression.

Results: From June 2016 to Jan 2020, 3,332 SLE patients (199 male, 3,133 female) with a mean age of 36.34 ± 12.80 (10-91) years and the median disease duration of 3.43 years from 216 hospitals performed bundle self-assessments for 4,967 times in total. According to the HADS and SLEDAI-2K Assessment results, the prevalence of anxiety and depression in all patients was 36.7% and 39.3% respectively, which was significantly higher than that in the WHO survey in Chinese population and chronic disease patients. The proportion of patients achieved and failed on LLDAS was 53% and 47%, respectively. The prevalence of anxiety (A) and depression (D) was 19% and 27% among LLDAS achievers; 41% and 47% among LLDAS failures, respectively (pA< 0.01, pD< 0.01).

According to SLEDAI-2K, in LLDAS, LDA, MDA and HDA subgroups, the prevalence of anxiety and depression was 19%, 30%, 37%, 54% and 27%, 36%, 44%, 61%, respectively. The correlation coefficients of anxiety (A) and depression (D) with SLEDAI-2K were rA=0.9957 and rD=0.9819. It suggested that with the increase of disease activity, the proportion of SLE patients with anxiety and depression increased significantly. (Figure 1)

Conclusion: Conclusion: Higher prevalence of anxiety and depression were Associated with higher levels of disease activity in SLE patients. SSDM is an effective mobile interface to monitor and study entanglement of disease activity and mental health in SLE patients, which build a foundation for proactive interventions physically and mentally in future.


Disclosure: Y. Wang, None; H. Wei, None; R. Wu, None; J. Wu, None; S. Zhang, None; Q. Li, None; Y. Li, None; Y. Sun, None; Y. Zhao, None; Q. Shu, None; L. Kang, None; B. Wu, None; L. Qin, None; F. Jiang, None; H. Yang, None; J. Zhang, None; H. Xiao, None; B. Wu, None; Y. Jia, None; F. Xiao, None; L. Sun, None.

To cite this abstract in AMA style:

Wang Y, Wei H, Wu R, Wu J, Zhang S, Li Q, Li Y, Sun Y, Zhao Y, Shu Q, Kang L, Wu B, Qin L, Jiang F, Yang H, Zhang J, Xiao H, Wu B, Jia Y, Xiao F, Sun L. Disease Activity and Mental Health in SLE Patients: A Cross-section Study with Self-Assessments Based on Smart System of Disease Management (SSDM) Mobile Tools [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/disease-activity-and-mental-health-in-sle-patients-a-cross-section-study-with-self-assessments-based-on-smart-system-of-disease-management-ssdm-mobile-tools/. Accessed .
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to ACR Convergence 2020

ACR Meeting Abstracts - https://acrabstracts.org/abstract/disease-activity-and-mental-health-in-sle-patients-a-cross-section-study-with-self-assessments-based-on-smart-system-of-disease-management-ssdm-mobile-tools/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology