Date: Monday, October 22, 2018
Session Title: Imaging of Rheumatic Diseases Poster II: Ultrasound
Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
To evaluate and to compare ultrasonographic (US) features to clinical data and structural damage in symptomatic radiographic (RX) knee osteoarthritis (OA).
Patients with symptomatic (VAS-pain > 30/100) and RX (Kellgren-Lawrence (KL)≥2) knee OA responding to ACR criteria (1986) were included in a clinical trial N° NCT01544647. Clinical knee effusion, VAS-pain, WOMAC scores and radiographic severity (KL>2) were recorded. On US, effusion (≥ 4 mm), synovitis (depicted in the three subquadricipital ramps on B- and PD-modes) and Baker’s cyst (BC) were assessed according to binary and semi quantitative manners. Total US score (sum of effusion (0 to 6), synovitis scores (0- 15) and presence of BC (0-1)) varied from 0 to 22.
Results: 283 patients were evaluated (67% of women, mean age (SD): 64.1(±9.1) years, BMI: 29.1(±5.7), 58.4% with KL>2). Knee effusion was detected in 82 patients (29.1%) by clinical examination and in 185 patients (65.6%) by US. On US, synovitis was detected in 60.3% on B-mode and 28.0% on PD-mode. BC was observed in 70 patients (24.9%). The mean +/-SD effusion, synovitis and total US scores were 0.8±1.2, 2.5±2.6 and 3.6±3.4 respectively. For an US effusion score >2, more than 50% of knee effusions were clinically detected. Only effusion score was associated with VAS-pain (p=0.01) on univariate analysis. There was a significant association between RX severity and US effusion and synovitis scores (B-mode and DP-mode) in univariate and multivariate analysis (p<0.05).
US detected two times more knee effusion than clinical examination and only US effusion score demonstrated association with pain. US effusion and synovitis were strongly associated to structural damages.
To cite this abstract in AMA style:BAZIN O, Ngueyon Sime W, Desvignes A, Spitz E, Guillemin F, Rat AC, Chary-Valckenaere I, Loeuille D. Contribution of Ultrasonography Examination in Symptomatic Radiographic Knee OA [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/contribution-of-ultrasonography-examination-in-symptomatic-radiographic-knee-oa/. Accessed March 18, 2019.
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