ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 109

Clinical features of pediatric Behçet’s disease patients in Japan

Ken-ichi Yamaguchi1 and Satoshi Fujikawa2, 1Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, 2Immuno－Rheumatology Center, St.luke's International Hospital, Tokyo, Japan

Meeting: 2017 Pediatric Rheumatology Symposium

Keywords: ,

Session Information

Date: Thursday, May 18, 2017

Title: Clinical and Therapeutic Poster Session

Session Type: Abstract Submissions

Session Time: 5:30PM-7:00PM

Background/Purpose: To diagnose pediatric patients as Behçet’s disease (BD) is challenging. Sensitivity of four BD criteria, three BD criteria made for adult patients and Paediatric Behçet’s Disease study (PEDBD) criteria1, are not high enough for Japanese pediatric BD patients (51%, 60%, 70%, 47%). The aim of this study is to clarify differences in clinical characteristics between Japanese pediatric BD patients (JP) and Japanese adult BD patients (JA) or pediatric BD patients in other countries (OP)1.

Methods: We identified 51 cases of Japanese pediatric BD by questionnaire survey of pediatric rheumatologists in Japan. Then we compared their symptoms recognized at any time during disease course with those of other two groups.

Results: Oral ulcers were found with high frequency in all groups (JP 98%, JA 96%, OP 98%). Gastrointestinal symptom were higher in both pediatric groups (JP 45%, OP 40%) than adult group (JA 23%). In many of organ involvement, frequency of JP group were lower than other groups, Ocular (JP 24%, OP 33%, JA 61%), Central Nerve System (6%, 46%, 10%), Vascular (4%, 15%, 12%) respectively.

Conclusion: There may be differences in clinical features of BD due to onset of age or residential area. These differences could be a reason for difficulty to diagnose pediatric BD patient.

References

1. Isabelle Kone-Paut et. al.：Consensus classification criteria for paediatric Behcet’s disease from prospective observational cohort PEDBD. Ann Rheum Dis 2016;75:958-64

Disclosure: K. I. Yamaguchi, None; S. Fujikawa, None.

To cite this abstract in AMA style:

Yamaguchi KI, Fujikawa S. Clinical features of pediatric Behçet’s disease patients in Japan [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 4). https://acrabstracts.org/abstract/clinical-features-of-pediatric-behcets-disease-patients-in-japan/. Accessed .

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