ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP PRSYM
    • 2016-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • Register
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstract Number: 0624

Association of Regional Body Composition and Physical Function Using the Short Physical Performance Battery Among Peruvian Women with HIV

Diego Cabrera1, Mijahil Pavel Cornejo Ortega2, Yvett Pinedo3, Patricia Garcia4 and Evelyn Hsieh5, 1Yale University, Universidad Peruana Cayetano Heredia, Lima, Peru, 2Hospital Nacional Arzobispo Loayza, Lima, Peru, 3Hospital Nacional Arzobispo Loayza, Lima, 4Universidad Peruana Cayetano Heredia, Lima, Peru, 5Yale University School of Medicine; West Haven VA, New Haven, CT

Meeting: ACR Convergence 2020

Keywords: Aging, body composition

  • Tweet
  • Email
  • Print
Save to PDF
Session Information

Date: Saturday, November 7, 2020

Session Title: Infection-related Rheumatic Disease Poster

Session Type: Poster Session B

Session Time: 9:00AM-11:00AM

Background/Purpose: The musculoskeletal (MSK) system is significantly affected by HIV and its treatment. Changes in body composition can reflect important changes in bone and MSK health, particularly among populations at risk for developing fat redistribution syndromes, like HIV-positive women (HpW). Although more than half of HIV-infected population worldwide are women, there are limited data about characteristics of women aging with HIV in Latin American and the Caribbean (LAC). No studies from LAC have focused on the relationship between body composition changes and physical function among these individuals. We aimed to explore the scope of this problem among Peruvian women aging with HIV.

Methods: We enrolled HpW and HIV-negative women (HnW) ≥40 years of age receiving care at a large HIV clinic in Lima, Peru. Dual X-ray absorptiometry (DXA) was used to measure trunk and limb lean mass (LM) and fat mass (FM). Physical performance was assessed with the well-established Short Physical Performance Battery (SPPB) and physical strength with the grip strength test (GST) using a hand hydraulic dynamometer. We used linear regression to model associations between HIV status, body composition and physical test scores.

Results: 104 HpW and 212 HnW were enrolled with a mean age of 52.4±8.2 and 56.4±8.8 years (p< 0.001) and BMI of 26.4±5.1 and 27.6±4.1 kg/m2 (p=0.03), respectively. Among HpW, the mean years since HIV diagnosis was 11.8±6 and everyone was on antiretroviral treatment (9.9±5.3 years). Fat mass index (FMI) was 9.6±3 vs 10.9±2.7 kg/m2 (p< 0.001) between HpW and HnW, respectively. Overall mean SPPB score was 9.9 vs 10.8 between HpW and HnW, respectively (p< 0.001). Mean grip strength was 19.9±5.9 vs 19.8±5.4 kg (p=0.83) between HpW and HnW, respectively. In multivariate models adjusted by age and HIV status, increased trunk FM was independently associated with decreased SPPB score (p< 0.001), increased arm LM was independently associated with increased GST(p< 0.001) and increased arm %fat was independently associated with decreased GST (p< 0.001).

Conclusion: In this study, trunk FM and arm LM were independent predictors for the physical performance and function tests described, and HIV status was independently associated with SPPB score. Larger prospective studies are needed among PWH in LAC to help identify individuals at high risk for declines in physical function, and to inform prevention guidelines.

Table 1: Overall SPPB Scores and Sub-scores and Grip Strength according to HIV status

Table 2: Unadjusted and Adjusted Linear Regression for SPPB and Grip Strength


Disclosure: D. Cabrera, None; M. Cornejo Ortega, None; Y. Pinedo, None; P. Garcia, None; E. Hsieh, None.

To cite this abstract in AMA style:

Cabrera D, Cornejo Ortega M, Pinedo Y, Garcia P, Hsieh E. Association of Regional Body Composition and Physical Function Using the Short Physical Performance Battery Among Peruvian Women with HIV [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/association-of-regional-body-composition-and-physical-function-using-the-short-physical-performance-battery-among-peruvian-women-with-hiv/. Accessed January 18, 2021.
  • Tweet
  • Email
  • Print
Save to PDF

« Back to ACR Convergence 2020

ACR Meeting Abstracts - https://acrabstracts.org/abstract/association-of-regional-body-composition-and-physical-function-using-the-short-physical-performance-battery-among-peruvian-women-with-hiv/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2021 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.