Background/Purpose: Chronic
pain conditions are related poor overall health, economic burden, and mental
disorders including suicidal ideation (SI), suicide attempts (SA), and
completed suicides. Fibromyalgia is one of chronic pain syndrome that is a highly
prevalent condition in United States. We performed a systematic review and
meta-analysis of available articles that assess association between
fibromyalgia and suicidal ideation or suicidal attempt.

Methods: We
comprehensively searched the databases of MEDLINE and EMBASE from their dates
of inception to June 2015. The inclusion criteria were published articles that
reported prevalence or association of fibromyalgia and suicidal ideation or
suicidal attempt. The primary outcome was the odds ratio (OR) or risk ratio
(RR) of SI or SA compared between patients with and without fibromyalgia. The
secondary outcome was prevalence of SI or SA in the fibromyalgia group.

Results: From
53 full-text articles, 8 studies with a total of 202 participants were included
in the meta-analysis. Compared with non-fibromyalgia group, patients with
fibromyalgia had significantly higher chance of SI or SA (OR=2.15, 95% CI:
1.006 to 3.30). In addition, pooled prevalence of SI or SA was high (Pooled
prevalence= 0.11, 95% CI: 0.02 to 3.30).

Conclusion: We
have shown that SI and SA are prevalent among patients with fibromyalgia and
there is a significant association between these two conditions. These findings
underscore the importance of assessment of SI and SA among the individuals
presenting who have fibromyalgia.