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Abstract Number: 2439

A Description of Contraception Practices in the Ohio State University Lupus Cohort

Veronica Mruk1, Ashlee Weaver2, Alexa Zofia3, Emily Sullivan4, Kelly Morris5, Stacy P. Ardoin6, Elise Berlan7 and Alexa Meara8, 1The Nationwide Children's Hospital, Columbus, OH, 2The Ohio State University School of Medicine, Columbus, OH, 3The Ohio State University, Columbus, OH, 4The Ohio State Univeristy Wexner Medical Center, Columbus, OH, 5Rheumatology and Immunology, The Ohio State University, Columbus, OH, 6The Ohio State University Wexner Medical Center, Columbus, OH, 7Adolescent Medicine, Nationwide Children's Hospital, columbus, OH, 8Internal Medicine/Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH

Meeting: 2018 ACR/ARHP Annual Meeting

Keywords: patient outcomes and systemic lupus erythematosus (SLE), Reproductive Health

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Session Information

Date: Tuesday, October 23, 2018

Session Title: Reproductive Issues in Rheumatic Disorders Poster

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease, which predominantly affects women and reaches peak incidence during reproductive years. Periods of high disease activity are associated with maternal and fetal morbidity and mortality. Many medications, disease modifying anti-rheumatic drugs (DMARDS), used to treat SLE also have deleterious pregnancy effects. The literature provides clear guidelines for the best approaches to these practices for women with SLE; however, little is known about current practices. Our aim was to determine contraception practices within The Ohio State University (OSU) Lupus/Vasculitis/Glomerulonephritis (LVG) Registry.

Methods: The OSU LVG Registry prospectively collects clinical data of patient reported surveys including information on reproductive health. Per the Registry and chart review, patient reported sexual activity was assessed. An IRB approved retrospective chart review was conducted on female participants within the LVG cohort who received care for SLE between 2013 and 2018. Date collected included: patient demographics, sexual activity, contraceptive method (oral, surgical, devices, condom, or abstinence), and DMARD use.

Results: Within the registry, we had 259 female patients with SLE. Approximately half of the SLE cohort was on medications considered to be potentially teratogenic or non-compatible with pregnancy. Table 1 shows our SLE cohort demographics. 94% of the cohort self-reported as sexually active, with only about 25% reporting the use of prescription contraceptives (excluding post-menopausal women). An estimated 14% of sexually active patients reported using only condoms or abstinence while almost 27% use no method of contraception.

Conclusion: Within the LVG Cohort, SLE patients are on high risk medications with the potential for high risk pregnancy complications. This further demonstrates the need for assessing pregnancy intention, providing family planning counseling, and birth control methods in rheumatology practice. Further research is need

Table 1: SLE Cohort Demographics per Intake LVG Registry Questionnaire

Characteristics

(%)

Age (years)

Average age of patients

42.6

Average age at diagnosis

28.6

Sexually active

Yes – using birth control

31%

No — not using birth control

41%

Not sexually active

6%

Menopausal

22%

Not answered (N = 114)

44%

Race

Caucasian

57%

African American

36%

Asian

3%

Other

1%

Ethnicity

Hispanic / Latino

3%

Non-Hispanic

97%

Education

High school diploma or GED

15.79%

Associate’s degree or

equivalent

10.39%

Bachelor’s degree or equivalent

15.45%

Some post-secondary education

37.39%

Master’s degree or higher

10.80%

Question Not Answered

40%

Contraception method

Abstinence

0.4 %

Menopause

21%

None

26.5%

Sterilization

1.6 %

Ligation

4.3%

Hysterectomy

14%

Vasectomy

1.9%

IUD

10.5%

Implant

4.7%

Injection

2.7%

Pill-combo

2.3%

Pill-mini

3.9%

Patch

0%

Ring

0.8%

Condoms

13.2%

Diaphragm

0%

ed for the implementation of a sustainable patient and healthcare team education model in this high-risk population.


Disclosure: V. Mruk, None; A. Weaver, None; A. Zofia, None; E. Sullivan, None; K. Morris, None; S. P. Ardoin, None; E. Berlan, None; A. Meara, None.

To cite this abstract in AMA style:

Mruk V, Weaver A, Zofia A, Sullivan E, Morris K, Ardoin SP, Berlan E, Meara A. A Description of Contraception Practices in the Ohio State University Lupus Cohort [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/a-description-of-contraception-practices-in-the-ohio-state-university-lupus-cohort/. Accessed May 16, 2022.
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