Background/Purpose: Patient-centred care and improvement of daily life are the main components in chronic disease management. The aim of the study was to determine associations among age, Patient Empowerment, Engagement, and Activation status and Daily impairment in patients with Sjögren disease (SjD).

Methods: In this cross-sectional study, 164 patients with SjD (F/M: 157/7; mean age: 54.4±12.4 years, disease duration: 9.02±7.14 years) were included. Data were collected by clinical examinations and a questionnaire. The Patient Empowerment (n=7 items), Engagement (n=7 items), and Activation (n=7 items) Survey (PEEAS) scale, the 5-Level EQ-5D scale (EQ-5D-5L) for quality-of-life status (high score: good QoL status) as well as the EULAR SS Patient Reported Index (ESSPRI) score were used in the study. High scores reflected Empowered, Engaged and Active patients (7-35 points in each group) in PEEAS and good self-reported health status (0-100 mm: the best health status) whereas high score of Work Productivity and Activity Impairment (WPAI)-Daily impairment and ESSPRI score were associated with poor conditions. After preliminary analysis, moderation analysis was used to test the influence of age as a third variable (Z), on the relationship between dependent (Y; WPAI, PEEAS) and independent (X; self-reported health status) variables.

Results: Increase in age was correlated with decreases in scores of EQ-5D-5L (0.62±0.21), self-reported general health status (61.92±11.59), Empowerment, Engagement and Activation subgroups (26,65±4.33; 26.68±4.20; 25.10±6.20)(p < 0.05). Moreover, an elevated WPAI-Daily impairment score (43.59±22.20) was correlated with poorer self-reported general health status and younger age (p < 0.05). According to Moderator analysis, the negative impacts of self-reported health status (X) on WPAI-Daily impairment were stronger in young (Z) patients (p < 0.05). Similar relation was not seen for PEEAS subgroups for young patients (p >0.05).Low EQ-5D-5L score as well as elevated ESSPRI score (6.48±1.64) and long duration for ocular dryness were also associated with poor scores of Empowerment, Engagement and Activation in PEEAS scale (25.10±6.20)(p < 0.05).

Conclusion: This study highlights the relationships between age, self-reported health status, patient empowerment, engagement, and those actively patient in their management. In addition, younger individuals who have poorer health perception may experience greater impairment on a daily basis. Prolonged ocular dryness emphasizes the importance of tailored interventions to enhance patient-centred care.

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ACR Meeting Abstracts - https://acrabstracts.org/abstract/influence-of-age-on-daily-impairment-patient-empowerment-activation-and-engagement-in-patients-with-sjogrens-disease/