ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 0719

Increased Risk of Venous Thromboembolism in Adult Patients with Idiopathic Inflammatory Myopathies

Gözde Kübra Yardımcı1, Arzu Taghiyeva2, Enes Erul2, Bayram Farisogulları3, Levent Kilic1 and Sule Apraş Bilgen1, 1Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 2HACETTEPE UNIVERSITY, Ankara, Turkey, 3Division of Rheumatology, Department of Internal Medicine Faculty of Medicine, Hacettepe University, Ankara, Turkey

Meeting: ACR Convergence 2021

Keywords: ,

Session Information

Date: Sunday, November 7, 2021

Title: Muscle Biology, Myositis & Myopathies Poster (0683–0722)

Session Type: Poster Session B

Session Time: 8:30AM-10:30AM

Background/Purpose: Idiopathic inflammatory myopathies (IIMs) patients have a higher risk of venous thromboembolism (VTE) [1]. We aimed to assess the incidence of thrombosis and associated factors in IIMs patients.

Methods: 93 IIMs patients (44 dermatomyositis and 49 polymyositis) were retrospectively reviewed to identify patients who had experienced a thrombosis during the follow-up period. The patients’ clinical characteristics, association with cancer, presence of thrombophilia, APSL autoantibodies, and intravenous immunoglobulin (IVIG) therapy were systematically analysed.

Results: 93 cases with IIMs (64.5% female) were followed median 27.6 (IQR:11.6-75.4) months. The incidence of a thrombotic event in the total cohort was 8.6%. Median time to development of venous thromboembolism was 4 (IQR:1-28,75) months and 75% of the thrombotic events developed during the first year after IIM diagnosis (Table). Venous thromboembolism was not associated with age, sex, cancer or IVIG therapy.

Conclusion: The prevalence of thrombotic events was 8.6% in our cohort and the risk of VTE is highest in the first year of disease. Further studies are needed to identify high-risk patients and to test the role of thromboprophylaxis.

Table: Patients with polymyositis/dermatomyositis and venous thromboembolism

Disclosures: G. Yardımcı, None; A. Taghiyeva, None; E. Erul, None; B. Farisogulları, None; L. Kilic, None; S. Apraş Bilgen, None.

To cite this abstract in AMA style:

Yardımcı G, Taghiyeva A, Erul E, Farisogulları B, Kilic L, Apraş Bilgen S. Increased Risk of Venous Thromboembolism in Adult Patients with Idiopathic Inflammatory Myopathies [abstract]. Arthritis Rheumatol. 2021; 73 (suppl 9). https://acrabstracts.org/abstract/increased-risk-of-venous-thromboembolism-in-adult-patients-with-idiopathic-inflammatory-myopathies/. Accessed .

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