Session Information
Date: Monday, November 9, 2015
Title: Epidemiology and Public Health III: Risk Factors, Treatment and Outcomes of Gout and OA
Session Type: ACR Concurrent Abstract Session
Session Time: 4:30PM-6:00PM
Knee Pain
Burden is Associated with Decreased Motor Performance: Data from the
Osteoarthritis Initiative
Background/Purpose: The influence of knee pain
perception on daily life motor performance in knee osteoarthritis (OA) patients
has not been established. We examined the effect of knee pain on objectively
measured cadence, a measure of motor performance in daily life, among
community-dwelling adults with or at high risk for knee osteoarthritis.
Methods: Activity was objectively measured by
accelerometer on 2,001 participants with or at risk of radiographic knee OA at
the Osteoarthritis Initiative (OAI) 48-month clinic visit using ActiGraph GT1M
uniaxial accelerometers (ActiGraph; Pensacola, FL). Participants were
instructed to wear the sensor for seven consecutive days at least 10 hours per day.
Analysis was restricted to those with at least four valid days of wear. Cadence
is defined as the number of steps taken in a minute. The average maximum
cadence/day was determined by identifying the maximum duration of moderate/vigorous
activity (MVPA) and dividing the number of steps taken in the MVPA duration by MVPA
minutes per day. These were then averaged over the number of valid days of wear.
The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was
administered to assess the pain burden. Analysis
of covariance was used to estimate sex-specific means (± standard error) of
cadence across five categories of WOMAC pain (i.e.,
no pain and approximate quartiles of the non-zero pain score distribution),
with adjustment for age, race, and body mass index.
Results: We included 1937 participants, 55% women,
and with mean age of 65.1 (±9.1) years. Figure 1 shows a gradual
decline in cadence with increasing WOMAC pain score. Mean cadence was
significantly lower among men with WOMAC pain score >6 and significantly
lower among women with WOMAC pain score >3, as compared to sex-specific
means of participants with no pain.
Conclusion: Higher knee pain burden is
associated with decreased motor performance in daily life as measured by
cadence in both women and men. With the proliferation of accelerometers in
smartphones, cadence may be an important outcome measure for interventions
targeting pain in knee OA.
|
|
|
Average Maximum Daily Cadence (steps/minute) |
|||||||||
|
WOMAC pain score (non-zero quartiles) |
n |
Men |
p-value* |
Women |
p-value* |
||||||
|
0 |
682 |
102.88 |
± |
1.67 |
100.81 |
± |
1.55 |
||||
|
1 |
285 |
102.02 |
± |
2.67 |
0.7845 |
101.73 |
± |
2.31 |
0.7375 |
||
|
2-3 |
392 |
104.20 |
± |
2.20 |
0.6329 |
97.23 |
± |
2.03 |
0.1607 |
||
|
4 to 6 |
310 |
100.14 |
± |
2.44 |
0.3557 |
92.21 |
± |
2.31 |
0.0021 |
||
|
>6 |
268 |
|
89.99 |
± |
2.83 |
<.0001 |
|
86.76 |
± |
2.39 |
<.0001 |
|
Mean ± standard error; means adjusted for age, race, and BMI |
|||||||||||
|
* Comparison of sex-specific mean with WOMAC pain score=0 group |
|||||||||||
To cite this abstract in AMA style:
Razjouyan J, Najafi B, Ashbeck E, Dunlop DD, Lee J, Hamilton L, Kwoh CK. Knee Pain Burden Is Associated with Decreased Moderate to Vigorous Physical Activity: Data from the Osteoarthritis Initiative [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/knee-pain-burden-is-associated-with-decreased-moderate-to-vigorous-physical-activity-data-from-the-osteoarthritis-initiative/. Accessed .« Back to 2015 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/knee-pain-burden-is-associated-with-decreased-moderate-to-vigorous-physical-activity-data-from-the-osteoarthritis-initiative/