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Abstracts tagged "Vitamin D"

  • Abstract Number: 1709 • 2015 ACR/ARHP Annual Meeting

    Subclinical Atherosclerosis in Patients with Psoriatic Arthritis and the Role of Vitamin D

    Montserrat Robustillo-Villarino1, Cristina Vergara-Dangond1, Gloria Albert Espi1, Marcos Cerqueira2, Desamparados Ybañez García1, Elia Valls1, Elvira Vicens-Bernabeu1, Juan José Alegre1 and Àngels Martínez-Ferrer1, 1Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, 2Hospital de Ponte de Lima, ULSAM, Department of Rheumatology,Hospital de Ponte de Lima, ULSAM, Ponte de Lima, Portugal

    Background/Purpose: Psoriatic arthritis (PsA) is associated with increased cardiovascular risk (CV)[i]. Several studies associate low levels of 25-hydroxivitamin D (25OHD) with a greater prevalence of…
  • Abstract Number: 2047 • 2015 ACR/ARHP Annual Meeting

    A Randomised Double-Blind Placebo-Controlled Trial of Vitamin D Supplementation in Juvenile-Onset Systemic Lupus Erythematosus: Effects on Microarchitecture Measured By HR-pQCT

    Glauce Lima1, Juliane Paupitz1, Nadia E Aikawa2, Jackeline Couto Alvarenga3, Eloisa Bonfá1 and Rosa M R Pereira4, 1Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Vitamin D has an important effect in bone quality and vitamin D deficiency in Juvenile-onset Systemic Lupus Erythematosus patients (JoSLE) may be associated with…
  • Abstract Number: 2958 • 2015 ACR/ARHP Annual Meeting

    Vitamin D, Cognition and Cerebral Structural Abnormalities in Childhood- Onset Systemic Lupus Erythematosus

    Nailu A. Sinicato1, Mariana Postal2, Aline Tamires Lapa2, Bruna B Siqueira3, Karina Pelicari2, Paula T Fernades3, Roberto Marini Sr.4 and Simone Appenzeller5, 1Pediatrics, State University of Campinas, Campinas, Brazil, 2Medicine, State University of Campinas, Campinas, Brazil, 3State University of Campinas, Campinas, Brazil, 4Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, 5Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil

    Background/Purpose: About 16-95% of SLE patients have vitamin D insufficiency. Vitamin D levels, especially vitamin D deficiency, are associated with cognitive performance in adults. We…
  • Abstract Number: 316 • 2015 ACR/ARHP Annual Meeting

    Effect of Vitamin D on Effusion-Synovitis in Knee Osteoarthritis:  a Randomized Controlled Trial

    Xia Wang1, Flavia Cicutinni2, Xingzhong Jin1, Benny Samuel Eathakkattu Antony3, Anita Wluka2,4,5, Weiyu Han1, Leigh Blizzard6, Tania Winzenberg7, Graeme Jones8 and Changhai Ding8, 1Menzies institute for medical research, University of Tasmania, Hobart, Australia, 2Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, 3Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, 4Epidemiology & Preventive Med, Monash University, Melbourne, Australia, 5Department of Epidemiology and Preventive Medicine, Monash University, Armadale, Australia, 6Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 7Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, 8Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: To examine the effect of vitamin D supplementation on synovial inflammation in patients with knee osteoarthritis (OA) and low vitamin D levels over 24…
  • Abstract Number: 368 • 2015 ACR/ARHP Annual Meeting

    The Effects of Monitoring on a Quality Indicator for Glucocorticoid–Induced Osteoporosis and Trends of the Drug Variation in a Japanese Hospital

    Masei Suda1, Masato Okada1, Yasuhiro Suyama2, Mitsumasa Kishimoto1 and Tokutaro Tsuda1, 1Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, 2Rheumatology, JR Tokyo General Hospital, Tokyo, Japan

    Background/Purpose: Glucocorticoid-induced osteoporosis (GIOP) is one of the most clinically significant side effects of glucocorticoid use, and the prevention of GIOP has become more important…
  • Abstract Number: 675 • 2015 ACR/ARHP Annual Meeting

    Vitamin D Deficiency in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis. Results of the CARMA Study

    Ana Urruticoechea1, Maria Auxiliadora Martin2, Santos Castañeda3, Carlos Alberto Sánchez-Piedra2, Carlos González-Juanatey4, Javier Llorca5, Federico Díaz-González6 and Miguel Angel Gonzalez-Gay7, 1Hospital Can Misses, Ibiza, Spain, 2Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 3Rheumatology, H.U. La Princesa, Madrid, Spain, 4Division or Cardiology, Hospital Lusus Augusti, Lugo, Spain, 5Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 6Investigation Unit, Sociedad Española de Reumatológía, Madrid, Spain, 7Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain

    Background/Purpose: To study the association between 25-hydroxyvitamin D (25(OH)D) levels and the clinical characteristics of patients with chronic inflammatory rheumatic diseases (CIRD). Methods: Cross section…
  • Abstract Number: 867 • 2015 ACR/ARHP Annual Meeting

    Simultaneous Measurement of 25-Hydroxyvitamin D and Procalcitonin in Granulomatosis with Polyangiitis (GPA): Differentiation of Activity from Infection?

    Mariana O Perez1, Ricardo M. Oliveira2, Valéria Caparbo3,4, Mauricio Levy-Neto5, Eloisa Bonfá4 and Rosa M R Pereira3, 1Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2RDO Diagnósticos Médicos, São Paulo, Brazil, 3Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5Rheumatology DIvision, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Vitamin D acts as innate and adaptive immune response immunomodulator. 25-hydroxyvitamin D (25OHD) deficiency was reported to be associated with autoimmune diseases flares and…
  • Abstract Number: 1212 • 2015 ACR/ARHP Annual Meeting

    Investigation of Vitamin D Supplement Use, Rheumatoid Arthritis-Related Autoimmunity and Joint Signs Among Those at Increased Risk for the Development of Rheumatoid Arthritis

    Elizabeth A. Bemis1, Ryan W. Gan2, Marie L. Feser3, Michael H. Weisman4, James R. O'Dell5, Ted R. Mikuls5, Jane H. Buckner6, Peter K. Gregersen7, Richard M. Keating8, M. Kristen Demoruelle9, Kevin D. Deane10, V. Michael Holers11 and Jill M. Norris12, 1Epidemiology, Epidemiology, Colorado School of Public Health, Aurora, CO, 2Colorado School of Public Health, University of Colorado Denver, Aurora, CO, 3Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 4Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 5University of Nebraska Medical Center, Omaha, NE, 6Benaroya Research Institute at Virginia Mason, Seattle, WA, 7Feinstein Insititute for Medical Research, Manhasset, NY, 8Division of Rheumatology, Scripps Health, La Jolla, CA, 9Rheumatology, University of Colorado School of Medicine, Aurora, CO, 10Division of Rheumatology, U Colo Denver, Aurora, CO, 11Rheumatology Division, Univ of Colorado School of Med, Aurora, CO, 12University of Colorado Denver, Aurora, CO

    Background/Purpose: Vitamin D has immunomodulatory properties, and could be a protective factor against rheumatoid arthritis (RA). Anti-cyclic citrullinated peptide (anti-CCP) autoantibodies and swollen small joints…
  • Abstract Number: 1996 • 2014 ACR/ARHP Annual Meeting

    Improvement in Basic Bone Health Knowledge Among VA Primary Care Practitioners during a Focused Musculoskeletal Mini-Residency

    Mathilde Pioro1, Nancy Fisher1, Marissa Grotzke2, Grant W. Cannon3 and Michael Battistone4, 1Rheumatology, Cleveland Veterans Affairs Medical Center, Cleveland, OH, 2Salt Lake CIty Veterans Affairs Medical Center, Salt Lake CIty, UT, 3Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, 4University of Utah Health Sciences Center, Salt Lake City, UT

    Background/Purpose: Osteopenia and osteoporosis are common yet underrecognized in the veteran population. Methods: We tested basic bone health related knowledge among Veterans Affairs (VA) primary…
  • Abstract Number: 1923 • 2014 ACR/ARHP Annual Meeting

    Vitamin D Restores Lupus Myeloid Angiogenic Cell Function Via Down-Regulation of IP-10/CXCL-10

    John A. Reynolds1, David W. Ray2, Yvonne Alexander3 and Ian N. Bruce4, 1Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, United Kingdom, Manchester, United Kingdom, 2Institute of Human Development, Institute of Human Development, The University of Manchester, Manchester, United Kingdom, 3Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, 4Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom

    Background/Purpose Endothelial repair is important for the maintenance of vascular integrity and is impaired in patients with SLE.  Myeloid angiogenic cells (MACs) contribute to endothelial…
  • Abstract Number: 1824 • 2014 ACR/ARHP Annual Meeting

    A Randomized Double-Blind Placebo-Controlled Trial of Vitamin D Supplementation in Juvenile-Onset Systemic Lupus Erythematosus: Improvement in Disease Activity and Fatigue Scores

    Glauce Lima, Juliane Paupitz, Liliam Takayama, Eloisa Bonfa and Rosa M R Pereira, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose Vitamin D has an important immunomodulatory effect but there are no clinical trials that directly addressed the benefit from boosting the serum level of…
  • Abstract Number: 1749 • 2014 ACR/ARHP Annual Meeting

    Molecular Mechanisms Underlying 1,25(OH)2D3-Mediated Suppression of Th17 Cell Activity

    Wendy Dankers1,2, Jan Piet van Hamburg2,3, Wida Razawy1,2, Nadine Davelaar1,2, Anne-Marie Mus1,2, Patrick Asmawidjaja1,2, Johannes van Leeuwen4, Edgar Colin5 and Erik Lubberts1,2, 1Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 2Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 3Rheumatology, Erasmus MC, Rotterdam, Netherlands, 4Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 5Rheumatology, ZGT, Almelo, Netherlands

    Background/Purpose Vitamin D has suppressive effects on autoimmune diseases, such as rheumatoid arthritis (RA). Within these diseases, Th17 cells play a crucial role in the…
  • Abstract Number: 1394 • 2014 ACR/ARHP Annual Meeting

    Low Vitamin D Level Is Not Associated with Increased Risk of Cardiovascular Disease in Rheumatoid Arthritis Patients

    Tarun S. Sharma1, Xiaoqin Tang2, Deepak Vedamurthy3, Jonida Cote4 and Androniki Bili4, 1Rheumatology, Geisinger Medical Center, Danville, PA, 2Biostatistics, Geisinger Center for Health Research, Danville, PA, 3Hospital Medicine, Geisinger Medical Center, Danville, PA, 4Rheumatology, Geisinger Health System, Danville, PA

    Background/Purpose:  Cardiovascular disease (CVD) is the leading cause of death in patients with Rheumatoid Arthritis (RA).  Vitamin D deficiency is prevalent in RA and it…
  • Abstract Number: 606 • 2014 ACR/ARHP Annual Meeting

    The Immunological Basis of the Sex-Bias in Ankylosing Spondylitis:  Th17 Expansion Is Restricted to Male Patients and Correlates with Sex-Related Alteration in Vitamin D Metabolism

    Eric Gracey1,2, Blerta Green2, Paul Yip3, Renise Ayearst4, Ammepa Anton5, Aifeng Lin2 and Robert D. Inman6, 1Immunology, University of Toronto, Toronto, ON, Canada, 2Genetics and Development, University Health Network, Toronto, ON, Canada, 3Clinical Biochemistry, University Health Network, Toronto, ON, Canada, 4University Health Network, Toronto, ON, Canada, 5Rheumatology, University Health Network, Toronto, ON, Canada, 6Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose : Ankylosing spondylitis (AS) is an inflammatory arthritis of the spine, which has a major impact on function and quality of life. AS is…
  • Abstract Number: 711 • 2013 ACR/ARHP Annual Meeting

    1,25(OH)2D3 Inhibits Th17 Cytokine Production and RORγt Expression Through GATA3/IL4-Dependent and -Independent Mechanisms

    Wendy Dankers1, Jan Piet van Hamburg2,3, Anne-Marie Mus1, Patrick S. Asmawidjaja1, Johannes van Leeuwen4, Rudi W. Hendriks5, Louis Boon6, Edgar Colin7 and Erik Lubberts1,8, 1Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 2Rheumatology, Erasmus MC, Rotterdam, Netherlands, 3Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 4Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 5Pulmonary Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, 6Bioceros, Utrecht, Netherlands, 7Department of Rheumatology, ZGT, Almelo, Netherlands, 8Erasmus Medical Center, Rheumatology, Rotterdam, Netherlands

    Background/Purpose: Vitamin D has suppressive effects on autoimmune diseases, such as rheumatoid arthritis (RA). One important mechanism of disease suppression by vitamin D is inhibition…
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