Abstracts tagged "Vitamin D"

Abstract Number: 867 • 2015 ACR/ARHP Annual Meeting
Simultaneous Measurement of 25-Hydroxyvitamin D and Procalcitonin in Granulomatosis with Polyangiitis (GPA): Differentiation of Activity from Infection?
Mariana O Perez¹, Ricardo M. Oliveira², Valéria Caparbo^3,4, Mauricio Levy-Neto⁵, Eloisa Bonfá⁴ and Rosa M R Pereira³, ¹Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²RDO Diagnósticos Médicos, São Paulo, Brazil, ³Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁵Rheumatology DIvision, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Vitamin D acts as innate and adaptive immune response immunomodulator. 25-hydroxyvitamin D (25OHD) deficiency was reported to be associated with autoimmune diseases flares and…
Abstract Number: 1212 • 2015 ACR/ARHP Annual Meeting
Investigation of Vitamin D Supplement Use, Rheumatoid Arthritis-Related Autoimmunity and Joint Signs Among Those at Increased Risk for the Development of Rheumatoid Arthritis
Elizabeth A. Bemis¹, Ryan W. Gan², Marie L. Feser³, Michael H. Weisman⁴, James R. O'Dell⁵, Ted R. Mikuls⁵, Jane H. Buckner⁶, Peter K. Gregersen⁷, Richard M. Keating⁸, M. Kristen Demoruelle⁹, Kevin D. Deane¹⁰, V. Michael Holers¹¹ and Jill M. Norris¹², ¹Epidemiology, Epidemiology, Colorado School of Public Health, Aurora, CO, ²Colorado School of Public Health, University of Colorado Denver, Aurora, CO, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶Benaroya Research Institute at Virginia Mason, Seattle, WA, ⁷Feinstein Insititute for Medical Research, Manhasset, NY, ⁸Division of Rheumatology, Scripps Health, La Jolla, CA, ⁹Rheumatology, University of Colorado School of Medicine, Aurora, CO, ¹⁰Division of Rheumatology, U Colo Denver, Aurora, CO, ¹¹Rheumatology Division, Univ of Colorado School of Med, Aurora, CO, ¹²University of Colorado Denver, Aurora, CO
Background/Purpose: Vitamin D has immunomodulatory properties, and could be a protective factor against rheumatoid arthritis (RA). Anti-cyclic citrullinated peptide (anti-CCP) autoantibodies and swollen small joints…
Abstract Number: 1460 • 2015 ACR/ARHP Annual Meeting
Association of Vitamin D Receptor Polymorphism with Juvenile Idiopathic Arthritis (JIA)
Fernanda Falcini^1,2, Francesca Marini³, Stefano Stagi⁴, Gemma Lepri², Donato Rigante⁵, Marco Matucci-Cerinic² and M. L. Brandi³, ¹Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Firenze, Italy, ²Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Italy, Florence, Italy, ³University of Florence, Dept. of Surgery and Translational Medicine, Florence, Italy, ⁴Pediatric Endocrinology Unit, Anna Meyer Children’s Hospital, University of Florence, Pediatric Endocrinology Unit, Anna Meyer Children’s Hospital, Firenze, Italy, ⁵Istitute of Pediatrics, Università Cattolica del Sacro Cuore, Rome, Italy
Background/Purpose: JIA is the most common chronic arthritis of childhood. Vitamin D is a potential immuno-modulator in many conditions, including autoimmune diseases. Its influence in…
Abstract Number: 1608 • 2015 ACR/ARHP Annual Meeting
Protective Role of the Vitamin D Receptor Apai (rs7975232) Polymorphism Against Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis from Northern Spain
Raquel López-Mejías¹, Fernanda Genre¹, Sara Remuzgo-Martínez¹, Gema Robledo², Begoña Ubilla¹, Veronica Mijares¹, Javier Llorca³, Montserrat Robustillo-Villarino⁴, Alfonso Corrales¹, Carlos González-Juanatey⁵, Jose A. Miranda-Filloy⁶, Trinitario Pina⁷, Ricardo Blanco⁷, Esther Vicente⁸, Juan José Alegre⁹, Cesar Magro¹⁰, Enrique Raya¹¹, Beatriz Tejera¹², Marco A Ramírez Huaranga¹³, Ivan Ferraz-Amaro¹², Santos Castañeda¹⁴, Javier Martín² and Miguel A. Gonzalez-Gay^1,15, ¹Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, ²Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, Granada, Spain, ³Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, ⁴Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ⁵Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, ⁶Rheumatology Division, Hospital Lucus Augusti, Lugo, Spain, ⁷Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁸Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, ⁹Rheumatology, Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ¹⁰Rheumatology Department, Hospital Clínico San Cecilio, Granada, Spain, ¹¹Rheumatology, Hospital Clínico San Cecilio, Granada, Spain, ¹²Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ¹³Rheumatology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, ¹⁴Rheumatology, H.U. La Princesa, Madrid, Spain, ¹⁵Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Several vitamin D receptor (VDR) polymorphisms have been associated with cardiovascular (CV) and autoimmune diseases. Carotid plaques are surrogate markers of severe atherosclerotic disease.…
Abstract Number: 1709 • 2015 ACR/ARHP Annual Meeting
Subclinical Atherosclerosis in Patients with Psoriatic Arthritis and the Role of Vitamin D
Montserrat Robustillo-Villarino¹, Cristina Vergara-Dangond¹, Gloria Albert Espi¹, Marcos Cerqueira², Desamparados Ybañez García¹, Elia Valls¹, Elvira Vicens-Bernabeu¹, Juan José Alegre¹ and Àngels Martínez-Ferrer¹, ¹Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ²Hospital de Ponte de Lima, ULSAM, Department of Rheumatology,Hospital de Ponte de Lima, ULSAM, Ponte de Lima, Portugal
Background/Purpose: Psoriatic arthritis (PsA) is associated with increased cardiovascular risk (CV)[i]. Several studies associate low levels of 25-hydroxivitamin D (25OHD) with a greater prevalence of…
Abstract Number: 2047 • 2015 ACR/ARHP Annual Meeting
A Randomised Double-Blind Placebo-Controlled Trial of Vitamin D Supplementation in Juvenile-Onset Systemic Lupus Erythematosus: Effects on Microarchitecture Measured By HR-pQCT
Glauce Lima¹, Juliane Paupitz¹, Nadia E Aikawa², Jackeline Couto Alvarenga³, Eloisa Bonfá¹ and Rosa M R Pereira⁴, ¹Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Vitamin D has an important effect in bone quality and vitamin D deficiency in Juvenile-onset Systemic Lupus Erythematosus patients (JoSLE) may be associated with…
Abstract Number: 2958 • 2015 ACR/ARHP Annual Meeting
Vitamin D, Cognition and Cerebral Structural Abnormalities in Childhood- Onset Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Mariana Postal², Aline Tamires Lapa², Bruna B Siqueira³, Karina Pelicari², Paula T Fernades³, Roberto Marini Sr.⁴ and Simone Appenzeller⁵, ¹Pediatrics, State University of Campinas, Campinas, Brazil, ²Medicine, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, ⁵Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil
Background/Purpose: About 16-95% of SLE patients have vitamin D insufficiency. Vitamin D levels, especially vitamin D deficiency, are associated with cognitive performance in adults. We…
Abstract Number: 316 • 2015 ACR/ARHP Annual Meeting
Effect of Vitamin D on Effusion-Synovitis in Knee Osteoarthritis: a Randomized Controlled Trial
Xia Wang¹, Flavia Cicutinni², Xingzhong Jin¹, Benny Samuel Eathakkattu Antony³, Anita Wluka^2,4,5, Weiyu Han¹, Leigh Blizzard⁶, Tania Winzenberg⁷, Graeme Jones⁸ and Changhai Ding⁸, ¹Menzies institute for medical research, University of Tasmania, Hobart, Australia, ²Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, ³Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ⁴Epidemiology & Preventive Med, Monash University, Melbourne, Australia, ⁵Department of Epidemiology and Preventive Medicine, Monash University, Armadale, Australia, ⁶Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁷Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, ⁸Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: To examine the effect of vitamin D supplementation on synovial inflammation in patients with knee osteoarthritis (OA) and low vitamin D levels over 24…
Abstract Number: 1996 • 2014 ACR/ARHP Annual Meeting
Improvement in Basic Bone Health Knowledge Among VA Primary Care Practitioners during a Focused Musculoskeletal Mini-Residency
Mathilde Pioro¹, Nancy Fisher¹, Marissa Grotzke², Grant W. Cannon³ and Michael Battistone⁴, ¹Rheumatology, Cleveland Veterans Affairs Medical Center, Cleveland, OH, ²Salt Lake CIty Veterans Affairs Medical Center, Salt Lake CIty, UT, ³Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁴University of Utah Health Sciences Center, Salt Lake City, UT
Background/Purpose: Osteopenia and osteoporosis are common yet underrecognized in the veteran population. Methods: We tested basic bone health related knowledge among Veterans Affairs (VA) primary…
Abstract Number: 1923 • 2014 ACR/ARHP Annual Meeting
Vitamin D Restores Lupus Myeloid Angiogenic Cell Function Via Down-Regulation of IP-10/CXCL-10
John A. Reynolds¹, David W. Ray², Yvonne Alexander³ and Ian N. Bruce⁴, ¹Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, United Kingdom, Manchester, United Kingdom, ²Institute of Human Development, Institute of Human Development, The University of Manchester, Manchester, United Kingdom, ³Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, ⁴Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom
Background/Purpose Endothelial repair is important for the maintenance of vascular integrity and is impaired in patients with SLE. Myeloid angiogenic cells (MACs) contribute to endothelial…
Abstract Number: 1824 • 2014 ACR/ARHP Annual Meeting
A Randomized Double-Blind Placebo-Controlled Trial of Vitamin D Supplementation in Juvenile-Onset Systemic Lupus Erythematosus: Improvement in Disease Activity and Fatigue Scores
Glauce Lima, Juliane Paupitz, Liliam Takayama, Eloisa Bonfa and Rosa M R Pereira, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose Vitamin D has an important immunomodulatory effect but there are no clinical trials that directly addressed the benefit from boosting the serum level of…
Abstract Number: 1749 • 2014 ACR/ARHP Annual Meeting
Molecular Mechanisms Underlying 1,25(OH)₂D₃-Mediated Suppression of Th17 Cell Activity
Wendy Dankers^1,2, Jan Piet van Hamburg^2,3, Wida Razawy^1,2, Nadine Davelaar^1,2, Anne-Marie Mus^1,2, Patrick Asmawidjaja^1,2, Johannes van Leeuwen⁴, Edgar Colin⁵ and Erik Lubberts^1,2, ¹Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ²Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ³Rheumatology, Erasmus MC, Rotterdam, Netherlands, ⁴Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁵Rheumatology, ZGT, Almelo, Netherlands
Background/Purpose Vitamin D has suppressive effects on autoimmune diseases, such as rheumatoid arthritis (RA). Within these diseases, Th17 cells play a crucial role in the…
Abstract Number: 1394 • 2014 ACR/ARHP Annual Meeting
Low Vitamin D Level Is Not Associated with Increased Risk of Cardiovascular Disease in Rheumatoid Arthritis Patients
Tarun S. Sharma¹, Xiaoqin Tang², Deepak Vedamurthy³, Jonida Cote⁴ and Androniki Bili⁴, ¹Rheumatology, Geisinger Medical Center, Danville, PA, ²Biostatistics, Geisinger Center for Health Research, Danville, PA, ³Hospital Medicine, Geisinger Medical Center, Danville, PA, ⁴Rheumatology, Geisinger Health System, Danville, PA
Background/Purpose: Cardiovascular disease (CVD) is the leading cause of death in patients with Rheumatoid Arthritis (RA). Vitamin D deficiency is prevalent in RA and it…
Abstract Number: 606 • 2014 ACR/ARHP Annual Meeting
The Immunological Basis of the Sex-Bias in Ankylosing Spondylitis: Th17 Expansion Is Restricted to Male Patients and Correlates with Sex-Related Alteration in Vitamin D Metabolism
Eric Gracey^1,2, Blerta Green², Paul Yip³, Renise Ayearst⁴, Ammepa Anton⁵, Aifeng Lin² and Robert D. Inman⁶, ¹Immunology, University of Toronto, Toronto, ON, Canada, ²Genetics and Development, University Health Network, Toronto, ON, Canada, ³Clinical Biochemistry, University Health Network, Toronto, ON, Canada, ⁴University Health Network, Toronto, ON, Canada, ⁵Rheumatology, University Health Network, Toronto, ON, Canada, ⁶Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose : Ankylosing spondylitis (AS) is an inflammatory arthritis of the spine, which has a major impact on function and quality of life. AS is…
Abstract Number: 1274 • 2013 ACR/ARHP Annual Meeting
Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus
Amit Saxena¹, Peter M. Izmirly², Joanne H. Reed³, Sara Sahl², Deborah Friedman⁴, Robert M. Clancy³ and Jill P. Buyon², ¹Rheumatology, New York University School of Medicine, New York, NY, ²Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Medicine, New York University School of Medicine, New York, NY, ⁴Division of Pediatric Cardiology, New York Medical College, Valhalla, NY
Background/Purpose: Women with anti-Ro antibodies face the risk of having a child with cardiac Neonatal Lupus (NL), characterized by congenital heart block and/or cardiomyopathy. Biomarkers…

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