Abstract Number: 0029 • ACR Convergence 2024
Effect of Metformin on the Incidence of Total Knee Replacement: A Systematic Review and Meta-Analysis
Background/Purpose: Osteoarthritis (OA) is among the most common debilitating conditions, causing disability and pain in older adults. For end-stage OA, total knee replacement (TKR) is…Abstract Number: 1195 • ACR Convergence 2024
The Relations of Analgesic Antidepressants Use to Knee or Hip Replacement Among Osteoarthritis Patients Compared to Selective Serotonin Reuptake Inhibitors in a Large Prospective Cohort
Background/Purpose: Some antidepressants and anticonvulsants are effective in treating pain through mechanisms thought to be independent from their effects on depression, such as tricyclic antidepressants…Abstract Number: 1209 • ACR Convergence 2024
Time to Knee Replacement by Kellgren-Lawrence Grade and Presence of Frequent Knee Pain in Two Large and Diverse Longitudinal Cohorts: Data from MOST and OAI
Background/Purpose: Receipt of knee replacement has been proposed by the FDA as a structural and symptom outcome for clinical trials of Disease Modifying Osteoarthritis Drugs…Abstract Number: 2088 • ACR Convergence 2024
Personalized Prediction of Pain and Function for Knee Osteoarthritis Patients 1 Year After Total Knee Arthroplasty Using Machine Learning
Background/Purpose: Accurate preoperative (pre-op) prediction of postoperative (post-op) patient-specific improvement and satisfaction in pain and function after total knee arthroplasty (TKA) for osteoarthritis (OA) is…Abstract Number: 2103 • ACR Convergence 2024
Synovial Inflammation Is Increased in Females with Knee Osteoarthritis
Background/Purpose: Symptomatic knee osteoarthritis (OA) is more common in women than men. We sought to compare clinical and histological features and synovial gene expression between…Abstract Number: 2376 • ACR Convergence 2024
Systemic Lupus Erythematosus Patients Exhibit Dynamic Changes in Disease-Associated Transcripts Following Total Knee or Total Hip Arthroplasty
Background/Purpose: Patients with systemic lupus erythematosus (SLE) undergoing total hip arthroplasty and total knee arthroplasty (THA and TKA) experience higher complication rates than osteoarthritis (OA)…Abstract Number: 0147 • ACR Convergence 2023
Leukotriene Inhibitors Effect on Post-Traumatic Osteoarthritis: A Real-World Evidence Comparative Effectiveness Study
Background/Purpose: Joint injuries frequently lead to post-traumatic osteoarthritis (OA), a disabling condition often affecting young adults, impacting their quality of life and creating substantial economic…Abstract Number: 1630 • ACR Convergence 2023
Patient-Reported Fatigue Associated with Joint Histopathology in Rheumatoid Arthritis
Background/Purpose: Fatigue or tiredness is an important symptom for patients with rheumatoid arthritis (RA), yet the factors associated with fatigue are poorly understood and may…Abstract Number: 1843 • ACR Convergence 2023
Detection of Clinically Relevant Subgroups in Patients Undergoing Knee Replacement Using Machine Learning
Background/Purpose: In the US the lifetime risk for Knee Replacement surgery (KR) is 7% for men and 9.5% for women, and this accounts for substantial…Abstract Number: 1919 • ACR Convergence 2023
Arthroplasty Outcomes in Immune Checkpoint Inhibitor-Treated Patients: A Single Center Series
Background/Purpose: Immune checkpoint inhibitors (ICI) have changed the landscape of cancer treatment dramatically, but because of their mechanism of action they are also known to…Abstract Number: 1985 • ACR Convergence 2023
Preliminary Results for the Total Knee Replacement Coaching Program for Patients Preparing to Undergo Total Knee Arthroplasty, a Pilot Randomized Trial
Background/Purpose: Up to 30% of patients with primary knee osteoarthritis (KOA) who have undergone Total Knee Replacement (TKR) continue to experience knee pain after surgery.High…Abstract Number: 1642 • ACR Convergence 2022
Mast Cells May Explain Sex Differences in Osteoarthritis Pain
Background/Purpose: Women are at increased risk for knee osteoarthritis(OA) and report more severe pain than men at the time of total knee arthroplasty. It has…Abstract Number: 1905 • ACR Convergence 2022
Does Exercise Before Surgery Predict Trajectories of Physical Activity After Knee Replacement?
Background/Purpose: Total knee replacement (TKR) is the definitive treatment for adults with knee osteoarthritis (OA) and is often successful in reducing pain and improving function.…Abstract Number: 1920 • ACR Convergence 2022
Gait and Physical Activity Predictors of Knee Replacement: A Machine Learning Analysis in the Multicenter Osteoarthritis Study
Background/Purpose: Rates of knee replacement (KR) due to knee osteoarthritis (OA) are rising exponentially and currently no interventions prevent KR. Gait and physical activity are…Abstract Number: 2087 • ACR Convergence 2022
Prospective Study of Clinical, Laboratory, and Patient-Reported Outcomes of Patients with Systemic Lupus Erythematosus Undergoing Total Hip and Total Knee Arthroplasty
Background/Purpose: Patients with SLE have doubled their utilization of THA and TKA, yet postoperative complications remain high. However, disease specific measures have not been assessed.…
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