ACR Meeting Abstracts

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Abstracts tagged "Takayasu.s arteritis"

  • Abstract Number: 1589 • ACR Convergence 2020

    An Initiative to Improve Timely Glucocorticoid Tapering in Vasculitis

    Arielle Mendel1, Daniel Ennis2, Shirley Lake3, Simon Carette4 and Christian Pagnoux5, 1Division of Rheumatology, McGill University, Montreal, QC, Canada, 2Division of Rheumatology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada, 3Division of Rheumatology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada, 4Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, 5Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Vasculitis guidelines recommend scheduled glucocorticoid (GC) tapering to avoid toxicity. In an audit of 130 consecutive new patients on GC assessed in our tertiary…
  • Abstract Number: 1692 • ACR Convergence 2020

    Poor Physical Activity Levels and Cardiorespiratory Fitness Among Patients with Childhood-Onset Takayasu Arteritis in Remission

    Camilla Astley1, Saulo Gil2, Gleice Clemente3, Maria Teresa Terreri4, Lucia Campos5, Nadia Aikawa5, Ana Lucia de-Sá Pinto2, Rosa Pereira5, Hamilton Roschel2 and Bruno Gualano2, 1University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 2University of Sao Paulo, Sao paulo, Brazil, 3Federal University of Sao Paulo, Sao Paulo, Brazil, 4Federal University of São Paulo, São Paulo, Brazil, 5Hospital das Clínicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Sao Paulo, Brazil

    Background/Purpose: Childhood-onset Takayasu Arteritis (c-TA) is a rare, granulomatous, chronic large-vessel vasculitis that involves mostly the aorta and its major branches with a high mortality…
  • Abstract Number: 1922 • ACR Convergence 2020

    Association of Leukocyte Populations in Peripheral Blood and Arterial Wall Inflammation Assessed by FDG-PET in Takayasu’s Arteritis and Giant Cell Arteritis

    K. Bates Gribbons1, Kaitlin Quinn2, Mark Ahlman3, Peter Merkel4 and Peter C. Grayson5, 1McGovern Medical School UT Houston, Houston, TX, 2Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, 3National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD, 4University of Pennsylvania, Philadelphia, PA, 5Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD

    Background/Purpose: Positron emission tomography (PET) is useful to demonstrate fluorodeoxyglucose (FDG) uptake in the large arteries in both Takayasu’s arteritis (TAK) and giant cell arteritis…
  • Abstract Number: 1923 • ACR Convergence 2020

    Angiographic Progression of Disease in Large-Vessel Vasculitis

    Kaitlin Quinn1, Himanshu Dashora2, Mark Ahlman3, Elaine Novakovich2 and Peter C. Grayson2, 1Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Washington, DC, 2Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD, 3National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD

    Background/Purpose: Angiography is essential to detect vascular disease in patients with large-vessel vasculitis (LVV).  Guidelines differ on the role of periodic angiography to monitor patients…
  • Abstract Number: 745 • 2019 ACR/ARP Annual Meeting

    Cardiac Involvements Are Related to Poor Prognosis in Patients with Takayasu’s Arteritis in China

    Yujiao Wang1, Lili Ma 1, Yan Yan 2, Ying Sun 3, Yongshi Wang 4, Xiaomin Dai 1, Zongfei Ji 5, Lingying Ma 1, Huiyong Chen 3 and Lindi Jiang 1, 1Zhongshan Hospital, Fudan University, Shanghai, China (People's Republic), 2Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, China (People's Republic), 3Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, 4Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, 5Department of Rheumatology, Zhongshan hospital, Fudan University, Shanghai, China (People's Republic)

    Background/Purpose: Heart involvements are closely associated with prognosis in patients with Takayasu’s arteritis (TA). This study was aimed to assess the long-term adverse outcomes of…
  • Abstract Number: 754 • 2019 ACR/ARP Annual Meeting

    Dynamic Distribution and Phenotype Shift from M1 to M2 of Macrophages in Vascular Lesions of Naïve and Treated Patients with Takayasu Arteritis

    Xiufang Kong1, Ming Xu 2, Xiaomeng Cui 2, Lingying Ma 2, Huiyong Chen 3, Lili Ma 2 and Lindi Jiang 2, 1University of Michigan & Fudan University, Ann Arbor, MI, 2Zhongshan Hospital, Fudan University, Shanghai, China (People's Republic), 3Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai

    Background/Purpose: Takayasu arteritis (TA) is a chronic inflammatory disease characterized by arterial vascular fibrosis. Type I (M1) and type II (M2) macrophages play very important…
  • Abstract Number: 1881 • 2018 ACR/ARHP Annual Meeting

    Discovery and Validation of Novel Disease Subsets in 806 Patients with Takayasu’s Arteritis across Four International Cohorts

    Ruchika Goel1, Katherine B. Gribbons2, Kathleen Maksimowicz-McKinnon3, Gary S. Hoffman4, Sathish Kumar5, George Joseph6, Raheesh Ravindran7, Aswin Nair8, David Cuthbertson9, Simon Carette10, Nader A. Khalidi11, Curry L. Koening12, Carol Langford13, Carol A. McAlear14, Paul A. Monach15, Larry W. Moreland16, Christian Pagnoux17, Philip Seo18, Antoine G. Sreih19, Kenneth J. Warrington20, Steven R. Ytterberg20, Peter A. Merkel21, Debashish Danda22 and Peter C. Grayson2, 1Rheumatology, Christian Medical College, Vellore Tamilnadu, India, 2National Institute of Arthritis, Musculoskeletal and Skin Disease, National Institutes of Health, Bethesda, MD, 3Rheumatology, Henry Ford Hospital, Detroit, MI, 4Rheumatology, Cleveland Clinic, Cleveland, OH, 5Child Health, Christian Medical College, Vellore, India, 6Cardiology, Christian Medical College, Vellore, India, 7Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, India, 8Clinical Immunology and Rheumatology, Christian Medical College, Vellore, India, 9Biostatistics and Informatics, Department of Pediatrics, Department of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 10Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 11Rheumatology, McMaster University, Hamilton, ON, Canada, 12Rheumatology, Division of Rheumatology, University of Utah, Salt Lake City, UT, 13Rheumatic and Immunologic Diseases, Department of Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 14Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 15Section of Rheumatology, Boston University School of Medicine, Boston, MA, 16Division of Rheumatology and Clinical Immunology, Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 17Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 18Medicine, Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 19Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 20Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, 21University of Pennsylvania, Philadelphia, PA, 22Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India, Vellore, India

    Background/Purpose: Takayasu’s arteritis (TAK) is characterized by variable patterns of damage throughout the large arteries. This study aimed to develop and validate a novel disease…
  • Abstract Number: 2780 • 2018 ACR/ARHP Annual Meeting

    Insufficient Use of Corticosteroids Results in Higher Relapse in Takayasu Arteritis

    Tomoyuki Muto1, Tsuyoshi Shirai2, Hiroshi Fujii1, Tomonori Ishii3 and Hideo Harigae3, 1Tohoku University Graduate School of Medicine, Sendai, Japan, 2Medicine, Stanford University School of Medicine, Stanford, CA, 3Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan

    Background/Purpose: Takayasu arteritis (TAK) is the chronic granulomatous inflammation of the aorta, its major branches. Although Corticosteroids, such as prednisolone (PSL), and immunosuppressants are key…
  • Abstract Number: 791 • 2017 ACR/ARHP Annual Meeting

    Aortic Dilatation in Patients with Large Vessel Vasculitis: A Longitudinal Case Control Study Using Positron Emission Tomography/Computed Tomography

    Filippo Crescentini1, Francesco Muratore2, Lucia Spaggiari3, Giulia Pazzola1, Luigi Boiardi1, Nicolò Pipitone1 and Carlo Salvarani4, 1Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio Emilia, Italy, 3Radiology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 4Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy

    Background/Purpose: To evaluate aortic diameter and predictors of aortic dilatation using FDG-PET/CT in a longitudinally followed cohort of patients with large vessel vasculitis (LVV) compared…
  • Abstract Number: 800 • 2017 ACR/ARHP Annual Meeting

    Measurement of Serum Cytokines during the Apparent Remission State of Takayasu Arteritis – What Do Cytokines Tell Us?

    Bruna Savioli1, Bruno Salu2, Marlon Vilela2, Maria Luiza Vilela Oliva2 and Alexandre W.S. Souza3,4, 1Internal Medicine - Rheumatology Division, Universidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, Brazil, 2Biochemistry, Universidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, Brazil, 3Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 4Internal Medicine, Universidade Federal de São Paulo, São Paulo, Brazil

    Background/Purpose: The definition of remission in Takayasu arteritis (TA) is a challenge in clinical practice, since smoldering arterial inflammation may occur without overt signs and…
  • Abstract Number: 803 • 2017 ACR/ARHP Annual Meeting

    Cardiovascular Risk Factors and Comorbid Diseases in Takayasu’s Arteritis

    Helin Masyan, Sinem Nihal Esatoglu, Ayse Merve Celik, Vedat Hamuryudan, Hasan Yazici and Emire Seyahi, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: In addition to the occlusive vasculitis, hypertension and accelerated atherosclerosis are probably risk factors of the cardiovascular complications in Takayasu arteritis (TA). Although, management…
  • Abstract Number: 106 • 2017 Pediatric Rheumatology Symposium

    Atypical manifestations and main misdiagnoses of Takayasu’s arteritis in childhood: a multicenter study of 71 patients

    Gleice Clemente1, Ana Paula Sakamoto2, Silvana B. Sacchetti Sr.3, Virgínia Ferriani4, Flavio Sztajnbok5, Sheila Oliveira6, Blanca Bica7, Andre Cavalcanti8, Teresa Robazzi9, Marcia Bandeira10 and Maria Teresa Terreri2, 1Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Univesidade Federal de São Paulo), São Paulo, Brazil, 2Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Universidade Federal de São Paulo), São Paulo, Brazil, 3Pediatric Rheumatology Unit, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil, 4Department of Pediatrics School of Medicine of Ribeirão Preto, University of São Paulo (USP-RP), Ribeirão Preto, Brazil, 5Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genoa, Italy, 6Pediatric Rheumatology, Universidade F Rio De Janeiro, Rio De Janeiro, Brazil, 7Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil, 8Novartis, Sao Paulo, Brazil, 9Pediatrics, Universidade Federal da Bahia, Salvador, Brazil, 10Pediatric Rheumatology Unit, Hospital Pequeno Príncipe, Curitiba, Brazil

    Background/Purpose:  Takayasu’s arteritis is a chronic inflammatory disease that affects the wall of large and medium-sized blood vessels. At the beginning of the disease, non-specific…
  • Abstract Number: 879 • 2016 ACR/ARHP Annual Meeting

    Associated Inflammatory Diseases in Takayasu’s Arteritis: The Many Faces of a Disease

    Sinem Nihal Esatoglu1, Ayse Merve Celik2, Didar Ucar3, Aykut Ferhat Celik4, Serdal Ugurlu5, Gulen Hatemi5, Melike Melikoglu5, Izzet Fresko5, Vedat Hamuryudan5, Huri Ozdogan6, Sebahattin Yurdakul5, Hasan Yazici5 and Emire Seyahi5, 1Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey, 3Istanbul University, Cerrahpasa Medical Faculty, Department of Ophthalmology, Istanbul, Turkey, 4Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, 5Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 6Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: Case reports and series suggest that Takayasu’s arteritis (TA) can co-exist with various inflammatory disorders. Inflammatory bowel disease [(IBD; Crohn's disease (CD) or ulcerative…
  • Abstract Number: 1968 • 2015 ACR/ARHP Annual Meeting

    Distinct Distribution Patterns of Large Vessel Vasculitis Assessed with 18f-FDG PET/CT: Evidence from Principal Component and Cluster Analyses

    Alessandra Soriano1, Giulia Pazzola1, Pierluigi Boiardi1, Francesco Muratore1, Pierluigi Macchioni1, Raffaella Aldigeri2, Massimiliano Casali3, Annibale Versari3 and Carlo Salvarani1,4, 1Rheumatology Unit, Internal Medicine Department, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 2Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy, 3Nuclear Medicine Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 4Rheumatology Unit, Internal Medicine Department, Arcispedale Santa Maria Nuova - IRCCS, and University of Modena and Reggio Emilia, Reggio Emilia, Italy

    Background/Purpose: The performance of 18F-FDG PET/CT in the diagnosis and assessment of disease activity of LVV has not been fully established. The interpretation of data…
  • Abstract Number: 3065 • 2015 ACR/ARHP Annual Meeting

    Evaluation and Validation of Case-Finding Algorithms for the Identification of Patients with Takayasu’s Arteritis in Large Healthcare Administrative Databases

    Narender Annapureddy1, Antoine G. Sreih2, Kevin Byram3, George Casey4, Vince Frangiosa5, Michael George6, Rebecca Sharim5, Sapna Sangani7 and Peter A. Merkel7, 1Rheumatology and Immunology, Vanderbilt University, Nashville, TN, 2Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 3Internal Medicine, Vanderbilt University, Nashville, TN, 4The Vasculitis Foundation, Kansas City, MO, 5Rheumatology, University of Pennsylvania, Philadelphia, PA, 6Department of Rheumatology, Hospital of the University of Pennsylvania, Philadelphia, PA, 7Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: To facilitate clinical care and research, validated algorithms are needed to accurately identify patients with Takayasu's arteritis (TAK). This study sought to evaluate and…
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