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Abstracts tagged "takayasu arteritis and vasculitis"

  • Abstract Number: 860 • 2016 ACR/ARHP Annual Meeting

    Assessment of the Frequency of Cardiovascular Risk Factors in Patients with Takayasu’s Arteritis

    Fatma Alibaz-Oner1, Matthew J. Koster2, Ali Ugur Unal3, Hale Gulcin Yildirim4, Ceylan Cikikci4, Cynthia S. Crowson5, Ashima Makol6, Steven R. Ytterberg6, Eric L. Matteson6, Haner Direskeneli7 and Kenneth J. Warrington6, 1Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Rheumatology, University of California Los Angeles, CA, USA Mayo Clinic, Rochester, MN, 3Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 4Marmara University Faculty of Medicine, Istanbul, Turkey, 5Health Sciences Research, Mayo Clinic, Rochester, MN, 6Rheumatology, Mayo Clinic, Rochester, MN, 7Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Accelerated atherosclerosis associated with chronic inflammation is one of the major complications of systemic inflammatory diseases. Takayasu arteritis (TAK) is a rare, systemic large-vessel…
  • Abstract Number: 881 • 2016 ACR/ARHP Annual Meeting

    Cardiopulmonary Involvement in Takayasu Arteritis

    David Brennan1, Kenneth J. Warrington2, Jean Schmidt3, Cynthia S. Crowson4 and Matthew J. Koster5, 1Internal Medicine, Mayo Clinic, Rochester, MN, 2Rheumatology, Mayo Clinic, Rochester, MN, 3Department of Internal Medicine and RECIF, Amiens University Hospital, Amiens, France, 4Health Sciences Research, Mayo Clinic, Rochester, MN, 5Rheumatology, University of California Los Angeles, CA, USA Mayo Clinic, Rochester, MN

    Background/Purpose:  Takayasu arteritis (TAK) is an inflammatory large-vessel vasculitis of unknown etiology affecting the proximal aorta and its primary branches. Heart disease is a major…
  • Abstract Number: 888 • 2016 ACR/ARHP Annual Meeting

    Prevalence of Takayasu Arteritis in Young Women Presenting with Acute Ischemic Heart Disease

    Giulio Cavalli, Alessandro Tomelleri, Elena Baldissera and Lorenzo Dagna, Internal Medicine and Clinical Immunology, Vita-Salute San Raffaele University, Milan, Italy

    Background/Purpose: Ischemic heart disease (IHD) is classically considered a disease of older men. However, 10% of myocardial infarctions occur in patients aged <45; also, in…
  • Abstract Number: 3054 • 2015 ACR/ARHP Annual Meeting

    Takayasu’s Arteritis Associated with Behçet’s Syndrome: A Case Series of 8 Patients

    Sinem Nihal Esatoglu1, Emire Seyahi2, Serdal Ugurlu2, Gulen Hatemi2, Melike Melikoglu2, Vedat Hamuryudan3 and Sebahattin Yurdakul1, 1Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, 2Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, 3Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: Takayasu's arteritis (TA) and Behçet's syndrome (BS) are both systemic vasculitis of an unknown etiology, each with unique involvement pattern. TA affects aorta and…
  • Abstract Number: 3059 • 2015 ACR/ARHP Annual Meeting

    Abnormal Body Composition in Takayasu Arteritis Patients: Role of Inflammatory Cytokines and Adipokines

    Thiago Ferreira da Silva, Mauricio Levy Neto, Valéria Caparbo, Liliam Takayama and Rosa M R Pereira, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Chronic inflammatory conditions including rheumatic diseases may alter body composition, especially lean and fat mass. In this process, adipokines and inflammatory cytokines appear to…
  • Abstract Number: 3068 • 2015 ACR/ARHP Annual Meeting

    Damage Assessment in Takayasu’s Arteritis

    Antoine G. Sreih1, Tanaz A. Kermani2, David Cuthbertson3, Simon Carette4, Gary S. Hoffman5, Nader A. Khalidi6, Curry L. Koening7, Carol A. Langford5, Carol McAlear8, Paul A. Monach9, Larry W. Moreland10, Christian Pagnoux11, Philip Seo12, Kenneth J. Warrington13, Steven R. Ytterberg14 and Peter A. Merkel8, 1Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Rheumatology, University of California Los Angeles, Santa Monica, CA, 3Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 4Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 5Rheumatology, Cleveland Clinic, Cleveland, OH, 6McMaster University, Hamilton, ON, Canada, 7Division of rheumatology, George E. Wahlen Department of Veterans Affairs Medical Center Salt Lake City and University of Utah, University of Utah School of Medicine, Salt Lake City, UT, 8Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 9Section of Rheumatology, Vasculitis Center, Boston University School of Medicine, Boston, MA, 10Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 11Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 12Division of Rheumatology, Johns Hopkins, Baltimore, MD, 13Rheumatology, Mayo Clinic, Rochester, MN, 14Rheumatology Division, Mayo Clinic, Rochester, MN

       Background/Purpose: This study aimed to describe disease-related damage in Takayasu's arteritis (TAK) and evaluate damage assessment tools using data from a large longitudinal cohort. …
  • Abstract Number: 3227 • 2015 ACR/ARHP Annual Meeting

    Identification of Novel Protein-Coding Genetic Variants Associated with Takayasu Arteritis

    Paul Renauer1, Patrick Coit1, Peter A. Merkel2 and Amr H. Sawalha1, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Takayasu arteritis is a rare large vessel vasculitis of unclear etiology. Previous studies identified associations between Takayasu arteritis and genetic variants within HLA class…
  • Abstract Number: 2786 • 2014 ACR/ARHP Annual Meeting

    Aortitis: Outcomes from a Cohort of 196 Patients

    Alison Clifford1, Amr Arafat2, Jahanzaib Idrees2, Eric Roselli2, Carmela D. Tan3, E. Rene Rodriguez3, Lars Svensson2, Eugene Blackstone2 and Gary S. Hoffman1, 1Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, 2Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 3Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Idiopathic aortitis is a rare diagnosis that may occur in the context of a primary systemic vasculitis, as part of a systemic autoimmune disease,…
  • Abstract Number: 804 • 2014 ACR/ARHP Annual Meeting

    Vasculitis and Inflammatory Bowel Diseases: A Study of 32 Patients with Both Conditions and Systematic Review of the Literature

    Alice Sy1, Natasha Dehghan2, Nader A. Khalidi3, Lillian Barra4, Simon Carette5, David Cuthbertson6, Gary S. Hoffman7, Curry L Koening8, Carol A. Langford9, Carol McAlear10, Paul A. Monach11, Larry W. Moreland12, Philip Seo13, Ulrich Specks14, Steven R. Ytterberg15, Gert Van Assche16, Peter A. Merkel10 and Christian Pagnoux5, 1Medicine Division, London, ON, Canada, 2Rheumatology Division, Vancouver, BC, Canada, 3Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, 4Rheumatology, St. Joseph's Health Care, London, ON, Canada, 5Division of Rheumatology, University of Toronto, Toronto, ON, Canada, 6Department of Biostatistics, University of South Florida, Tampa, FL, 7Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, 8Division of rheumatology, George E. Wahlen Department of Veterans Affairs Medical Center Salt Lake City and University of Utah, University of Utah School of Medicine, Salt Lake City, UT, 9Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, 10University of Pennsylvania, Philadelphia, PA, 11Rheumatology, Boston University, Boston, MA, 12Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 13Johns Hopkins Vasculitis Center, Rheumatology Division, Johns Hopkins University, Baltimore, MD, 14Mayo Clinic, Rochester, MN, 15Rheumatology Division, Mayo Clinic, Rochester, MN, 16Mount Sinai Hospital, Toronto, ON, Canada

    Background/Purpose:  Small case series suggested that vasculitis and inflammatory bowel disease (IBD; Crohn’s disease [CD] or ulcerative colitis [UC]) can co-occur more commonly than the…
  • Abstract Number: 813 • 2014 ACR/ARHP Annual Meeting

    Long-Term Outcomes of Takayasu’s Arteritis Patients with Renal Artery Involvement

    Corisande Baldwin1, Aladdin Mohammad2 and David Jayne3, 1Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Dept. of Rheumatology, Lund University Hospital, Lund University, Lund, Lund, Sweden, 3Vasculitis and Lupus Clinic, Addenbrookes Hospital University of Cambridge, Cambridge, United Kingdom

    Background/Purpose: Takayasu's Arteritis (TAK) is a chronic inflammatory large vessel vasculitis characterized by granulomatous inflammation of the aorta and its branches. TAK incidence is 2.6/million…
  • Abstract Number: 88 • 2014 ACR/ARHP Annual Meeting

    Microbiomes of Inflammatory and Non-Inflammatory Thoracic Aortic Aneurysms

    Pauline Funchain*1,2,3, Gary S. Hoffman*4, Lars Svensson5, Eric Roselli5, Gosta Pettersson6, Douglas Johnston6, Edward Soltesz6, Ritu Chakravarti7, Alison Clifford8 and Charis Eng2, 1Genomic Medicine Institute, Lerner Research Institute, Cleveland, OH, 2Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, 3Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, 4Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, 5Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 6Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 7Lerner Research Institure, Cleveland Clinic, Cleveland, OH, 8Rheumatic and Immunologic Diseases, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Aortitis may occur in the context of multifocal large and medium-sized vessel diseases such as giant cell arteritis (GCA) or Takayasu arteritis (TAK) and…
  • Abstract Number: 1766 • 2013 ACR/ARHP Annual Meeting

    Role Of IL33 In The Inflammation Of Takayasu Arteritis

    David Saadoun1, Marlène Garrido2, Julien Gaudric3, Cloé Comarmond4, Michele Rosenzwacjg5 and Patrice Cacoub6, 1Groupe Hospitalier Pitié Salpétrière, Service de Médecine Interne, DHU i2B, Paris, France, 2I3 laboratory, Pitié-Salpétrière, Paris, France, 3Department of Vascular surgery GHPS, Paris, France, 4Internal Medicine and Clinical Imunology, Referal Center for Autoimmune diseases, Internal Medicine and Clinical Imunology, Hôpital Pitié Salpétrière, Paris, France, 5Department of Immunology GHPS, Paris, France, 6Médecine Interne 2, Hopital Pitié-Salpétrière, Paris, France

    Background/Purpose: Interleukin (IL)-33, a member of the IL-1 cytokine family, is a recently described novel activator of endothelial cells, which promotes adhesion molecules and proinflammatory…
  • Abstract Number: 1702 • 2013 ACR/ARHP Annual Meeting

    Identification of Multiple Genetic Susceptibility Loci in Takayasu’s Arteritis

    Guher Saruhan-Direskeneli1, Travis Hughes2, Patrick S. Coit2, Joel M. Guthridge3, Judith A. James4, Peter A. Merkel of behalf of the Vasculitis Clinical Research Consortium5, Haner Direskeneli on behalf of the Turkish Takayasu Study Group6 and Amr H. Sawalha2, 1Department of Physiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 2Division of Rheumatology, University of Michigan, Ann Arbor, MI, 3Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 6Department of Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: Takayasu’s arteritis is a rare inflammatory disease of large arteries. The etiology of Takayasu’s arteritis remains poorly understood, but genetic contribution to the disease…
  • Abstract Number: 1678 • 2013 ACR/ARHP Annual Meeting

    How Similar Are Extracranial Giant Cell Arteritis and Takayasu Arteritis?

    Tanaz A. Kermani1, Cynthia S. Crowson2, Francesco Muratore3, Jean Schmidt4, Eric L. Matteson5 and Kenneth J. Warrington6, 1Rheumatology, University of California Los Angeles, Los Angeles, CA, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 4Internal Medicine and RECIF, CHU Nord, Amiens, France, 5Rheumatology, Mayo Clinic, Rochester, MN, 6Division of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose:   The clinical and radiographic features of giant cell arteritis (GCA) with extracranial (large-vessel) involvement can be similar to those of Takayasu arteritis (TAK)…
  • Abstract Number: 1684 • 2013 ACR/ARHP Annual Meeting

    Early Combination Immunosuppression and Serial Non-Invasive Imaging Improves Outcome In Takayasu Arteritis

    Taryn Youngstein1, Michael Quinn1, James Peters1 and Justin C. Mason2, 1Rheumatology Unit, Hammersmith Hospital, Imperial College London, London, United Kingdom, 2Rheumatology and Vascular Sciences, Hammersmith Hospital, Imperial College London, London, United Kingdom

    Background/Purpose: Takayasu arteritis (TA) affects the aorta and its branches, pre-disposing to stenoses and aneurysmal dilatation. While morbidity remains high, evidence for efficacy of immunosuppressive…
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