Abstracts tagged "Systemic sclerosis"

Abstract Number: 1521 • 2012 ACR/ARHP Annual Meeting
A Possible Contribution of Decreased Cathepsin V Expression to the Development of Dermal Fibrosis, Proliferative Vasculopathy, and Altered Keratinocyte Phenotype in Systemic Sclerosis
Yoshihide Asano, Shinji Noda, Takehiro Takahashi, Sayaka Shibata, Kaname Akamata, Naohiko Aozasa, Takashi Taniguchi, Yohei Ichimura, Tetsuo Toyama, Hayakazu Sumida, Yoshihiro Kuwano, Koichi Yanaba and Shinichi Sato, Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
Background/Purpose: Cathepsin V (CTSV) is a proteolytic enzyme potentially modulating angiogenic processes, collagen degradation, and keratinocyte differentiation. Although our latest paper demonstrated that cathepsin B,…
Abstract Number: 1478 • 2012 ACR/ARHP Annual Meeting
Gender-Associated Differences in Disease Characteristics and Outcome in Systemic Sclerosis
Svetlana I. Nihtyanova¹, Voon H. Ong² and Christopher P. Denton³, ¹Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, ²Department of Rheumatology, The Royal Free and University College Medical School, London, United Kingdom, ³Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, London, United Kingdom
Background/Purpose: Although significant female gender predominance is seen in majority of large systemic sclerosis (SSc) cohorts, multiple studies have suggested that male gender generally associates…

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