Abstracts tagged "Systemic lupus erythematosus (SLE)"

Abstract Number: 101 • 2018 ACR/ARHP Annual Meeting
Regulation of Monocyte Function By Epstein Barr Virus Interleukin-10 (vIL10) in Systemic Lupus Erythematosus
Neelakshi R. Jog¹, Eliza Chakravarty¹, Joel M. Guthridge¹ and Judith A. James^2,3, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease characterized by periods of elevated and suppressed disease activity. Epstein Barr Virus (EBV) has been…
Abstract Number: 687 • 2017 ACR/ARHP Annual Meeting
Homocysteine Levels Are Independently Associated with Damage Accrual in Systemic Lupus Erythematosus Patients (SLE)
Paola Zeña-Huancas¹, Manuel Ugarte-Gil^2,3, Rocío Gamboa-Cárdenas¹, Francisco Zevallos¹, Mariela Medina¹, Victor Pimentel-Quiroz², Claudia Elera-Fitzcarrald¹, Omar Sarmiento-Velasquez¹, Cristina Reategui-Sokolova¹, Mariano Cucho-Venegas¹, José Alfaro-Lozano¹, Zoila Rodriguez-Bellido^1,4, Cesar A. Pastor-Asurza^1,4, Graciela S. Alarcón⁵ and Risto Perich-Campos^4,6, ¹Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ²Peru, GLADEL, Lima, Peru, ³Universidad Cientifica del Sur, Lima, Peru, ⁴Universidad Nacional Mayor de San Marcos, Lima, Peru, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Rheumatology, Hospital Guillermo Almenara Irigoyen, Lima, Peru
Background/Purpose: Homocysteine level is a predictor of the occurrence of cardiovascular diseases, however, its role as a predictor of damage in SLE has not been…
Abstract Number: 1646 • 2017 ACR/ARHP Annual Meeting
Cardiovascular disease in Systemic Lupus Erythematosus. The road to hell is paved with good intentions
Sophie Mavrogeni¹ and Loukia Koutsogeorgopoulou², ¹CMR Department, Onassis Cardiac Surgery Center, Athens, Greece, ²Department of Pathophysiology, Rheumatology Unit, National Kapodistrian University of Athens, Athens, Greece
Background/Purpose: Accurate diagnosis of cardiovascular involvement in systemic lupus erythematosus (SLE) remains challenging, because echocardiography (echo), the cornerstone tool used, has serious limitations. We hypothesized…
Abstract Number: 1654 • 2017 ACR/ARHP Annual Meeting
Predictive Factors According to Type of Infection in Systemic Lupus Erythematosus Patients: Data from a Multi-Ethnic, Multi-National, Latin-American Cohort
Victor R. Pimentel-Quiroz¹, Manuel Ugarte-Gil¹, Guillermo J. Pons-Estel², Daniel Wojdyla³, Mario Cardiel⁴, Virginia Pascual-Ramos⁵, Ignacio Garcia-De La Torre⁶, Leonor Barile⁷, Mary Carmen Amigo⁸, Luis H. Silveira⁹, Maria Josefina Sauza del Pozo¹⁰, Marlene Guibert-Toledano¹¹, Gil A. Reyes¹², Antonio Iglesias-Gamarra¹³, Gloria Vasquez¹⁴, José Fernando Molina¹⁵, Jose A Gómez-Puerta¹⁶, Luis Alonso Gonzalez¹⁷, Rosa Chacón-Díaz¹⁸, Maria H Esteva Spinetti¹⁹, Isaac Abadi¹⁹, Eduardo M. Acevedo-Vásquez²⁰, Jose Alfaro-Lozano²¹, Ines Segami²², Loreto Massardo²³, Oscar Neira²³, Emilia Sato²⁴, Eloisa Bonfa²⁵, Eduardo Borba²⁶, Graciela S. Alarcón²⁷ and Bernardo Pons-Estel²⁸, ¹Peru, GLADEL, Lima, Peru, ²GLADEL, Rosario, Argentina, ³GLADEL consultant, Rosario, Argentina, ⁴Centro de Investigación Clínica de Morelia SC, Morelia, Mexico, ⁵Instituto Nacional de Ciencias Médicas y Nutrició, Mexico City, Mexico, ⁶Immunology & Rheumatology, Centro de Est. de Invest. Bas. y Clin., S.C., Guadalajara, JAL, Mexico, ⁷GLADEL, Mexico, Mexico, ⁸Centro Medico ABC, Mexico, Mexico, ⁹Rheumatology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City DF, Mexico, ¹⁰Servicio de Reumatología, Instituto Mexicano de Seguro Social, Hospital de Especialidades Nº 25, Monterrey, Mexico, ¹¹Centro de Investigaciones Médico Quirúrgicas, Habana, Centro de Investigaciones Médico Quirúrgicas, Habana, La Habana, Cuba, ¹²GLADEL, Havana, Cuba, ¹³Clinical Development, Nordic Bioscience, Herlev, Denmark, ¹⁴GLADEL, Colombia, Antioquia, Colombia, ¹⁵GLADEL, Colombia, Antoquia, Colombia, ¹⁶Grupo de Reumatología, Universidad de Antioquia, Medellín, Colombia, ¹⁷Medicarte IPS, Medellín, Colombia, ¹⁸Servicio de Reumatología, Hospital Universitario de Caracas, Centro Nacional de Enfermedades Reumáticas, Caracas, Venezuela, ¹⁹GLADEL, Caracas, Venezuela (Bolivarian Republic of), ²⁰Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, ²¹Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ²²GLADEL, Peru, Lima, Peru, ²³GLADEL, Santiago, Chile, ²⁴Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²⁵Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²⁶Faculdade de Medicina, Hospital das Clínicas. Universidade de São Paulo, São Paulo, Brazil, ²⁷University of Alabama at Birmingham, Birmingham, AL, ²⁸GLADEL, Rosario, Santa Fe, Argentina
Background/Purpose: While infections are a one of the main causes of mortality in systemic lupus erythematosus (SLE), the type of infections and the factors predisposing…
Abstract Number: 2610 • 2017 ACR/ARHP Annual Meeting
Quantiferon Testing in a Clinical Trial of Systemic Lupus Erythematosus
Niti Goel¹, Stephen Wax², Amy Kao², Russell Reeve³ and Marsha Mackey⁴, ¹QuintilesIMS, Duke University School of Medicine, Durham, NC, ²EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA), Billerica, MA, ³QuintilesIMS, Durham, NC, ⁴QuintilesIMS, Rockville, MD
Background/Purpose: Tuberculosis (TB) has been reported to occur at a higher rate in SLE patients than in the general population. As a result, most clinical…
Abstract Number: 2619 • 2017 ACR/ARHP Annual Meeting
Hemophagocytic Syndrome in Patients from SLE Registry from the Spanish Society of Rheumatology (RELESSER)
Ana Lois-Iglesias¹, Francisco J. de Toro², Antonio Zea³, María Galindo⁴, Esther Uriarte⁵, Iñigo Rúa-Figueroa⁶ and JM Pego-Reigosa⁷, ¹Rheumatology, University Hospital A Coruña, A Coruña, Spain, ²Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruna, Spain, ³Hospital Ramón y Cajal. Madrid, Madrid, Spain, ⁴Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, ⁵Reumatología, Hospital de Donosti, Donosti, Spain, ⁶Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ⁷Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain
Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune systemic rheumatic disease that, in our area, presents hematologic manifestations in approximately 70% of cases1. Some of…
Abstract Number: 2627 • 2017 ACR/ARHP Annual Meeting
Characterization of Emergency Department Visits in an Urban Underserved Lupus Cohort
Justin Levinson¹, Maushmi Savjani¹, Diane Zisa² and Ellen M. Ginzler³, ¹Internal Medicine, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ²Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ³Rheumatology, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY
Background/Purpose: SLE patients frequently utilize the Emergency Department (ED), impacting the cost of care and quality of life. We performed a retrospective analysis of ED…
Abstract Number: 2629 • 2017 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus Patients Not Complaining Raynaud’s Phenomenon Display Lower Skin Blood Perfusion Than Healthy Subjects
Barbara Ruaro¹, Alberto Sulli¹, Sabrina Paolino², Carmen Pizzorni³, Veronica Tomatis¹, Massimo Patanè¹ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genoa, Italy, ²University of Genova, IRCCS San Martino, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genova, Italy, ³Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, Genova, Italy
Background/Purpose: A clinical feature of patients with primary Raynaud's phenomenon (PRP) is the presence of low skin blood perfusion (BP) at the level of hands…
Abstract Number: 2631 • 2017 ACR/ARHP Annual Meeting
Validation of Clinically Relevant Improvement in Children and Adolescents with cSLE
Pinar Ozge Avar Aydin¹, Michael J. Holland², Simone Appenzeller³, Stacy P. Ardoin⁴, Tadej Avcin⁵, Michael W. Beresford⁶, Brian M. Feldman⁷, Francisco Flores⁸, Marisa S. Klein-Gitelman⁹, Beatrice Goilav¹⁰, Raju Khubchandani¹¹, Deborah M. Levy¹², Angelo Ravelli¹³, Nicolino Ruperto¹⁴, Clovis A Silva¹⁵, Scott E. Wenderfer¹⁶, Jun Ying¹⁷ and Hermine I. Brunner¹, ¹Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil, ⁴Pediatric & Adult Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy, ⁶On Behalf of the UK JSLE Study Group, Liverpool, United Kingdom, ⁷Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁸Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁹Division of Pediatric Rheumatology/PDD PTD, Lurie Children's Hospital of Chicago/Northwestern University, Chicago, IL, ¹⁰Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY, ¹¹Department of Paediatrics, Jaslok Hospital and Research Center, Mumbai, India, ¹²Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹³University of Genova, IRCCS Istituto Giannina Gaslini, Genova, Italy, ¹⁴Istituto Giannina Gaslini, Genoa, Italy, ¹⁵Rheumatology Unit, Instituto da Criança, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, São Paulo, Brazil, ¹⁶Nephrology, Baylor College of Medicine, Texas Children's Hospital, houston, TX, ¹⁷Center for Biostatistical Services, University of Cincinnati College of Medicine, Cincinnati, OH
Background/Purpose: Childhood-onset systemic lupus erythematosus (cSLE) is a multisystem autoimmune disease that is characterized by episodes of flares followed by improvement in response to therapy.…
Abstract Number: 155 • 2017 Pediatric Rheumatology Symposium
A Single Center Review of Health Related Quality of Life in Children with Systemic Lupus Erythematosus Using the Pediatric Quality of Life Inventory Version 4.0 Generic Core Scale
JaLeen Rogers¹, Anna Carmela P. Sagcal-Gironella², Patricia Rosillo³, Andrea A. Ramirez⁴, Rosa Banuelos⁵ and Marietta M. de Guzman⁶, ¹Outcomes and Impact Services, Texas Children's Hospital, Houston, TX, ²Rheumatology, Texas Children's Hospital, Houston, TX, ³Allergy, Immunology and Rheumatology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, ⁴Pediatric Rheumatology, Texas Children's Hospital, Houston, TX, ⁵Texas Children's Hospital, Houston, TX, ⁶Department of Pediatrics, Division of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Background/Purpose: Systemic lupus erythematosus (SLE) can cause adverse effects in various aspects of daily functioning for pediatric patients. Measuring Health-related Quality of Life (HRQOL) provides…
Abstract Number: 1392 • 2016 ACR/ARHP Annual Meeting
Familial Aggregation of Autoimmune Diseases in Childhood and Adulthood Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Luciana de Oliveira², Aline Tamires Lapa², Lilian Tereza Costallat³, Roberto Marini Sr.⁴, Timothy B. Niewold⁵ and Simone Appenzeller⁶, ¹Pediatrics, State University of Campinas, Campinas, Brazil, ²Medicine, State University of Campinas, Campinas, Brazil, ³RUA EZEQUIEL MAGALHAES,26, Unicamp, Campinas, Brazil, ⁴Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, ⁵Rheumatology and Immunology, Mayo Clinic, Rochester, MN, ⁶Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil
Background/Purpose: Genetic factors play a role in SLE, evidenced by the high sibling risk ratio (λs=8–29) and higher concordance rates between monozygotic twins (>35%) compared…
Abstract Number: 1813 • 2016 ACR/ARHP Annual Meeting
Prevalence and Incidence of Systemic Lupus Erythematosus in Tucuman -Argentina
Luciana Gonzalez Lucero¹, Raul Sueldo², Alberto Ives Torres³, Alexia Cristofari³, Ana Lucía Barbaglia³, Ana Olea³, Ana Quinteros⁴, Gladys Seleme³, Francisco Colombres³, Dora Lia Vásquez³, Gustavo Arquez³, Gustavo Alberto Carrizo³, Hector Lazaro³, Maria Josefina Molina³, Laura Juarez³, Maria Constanza Bertolaccini⁵, Maria Olga Leal⁶, María Silvia Yacuzzi², Mariana Espindola Echazu³, Norma Robles De Garrone³, Rodolfo Orlando Dip³, Olga Romano³, Oscar Pera³, Silvia Paz³, Veronica Bellomio⁷, Maximiliano Machado Escobar², Silvia Rengel⁸, Liliana Galindo⁷, Mirta Santana² and Eleonora Lucero², ¹Rheumatology Unit, Hospital Padilla, Tucumán, Tucumán, Argentina, ²Hospital Angel Cruz Padilla, Tucumán, Argentina, ³Sociedad de Reumatología de Tucumán, tucuman, Argentina, ⁴Centro Integral Reumatológico, Tucuman, Argentina, ⁵Rheumatology, Hospital Angel Cruz Padilla, Tucumán, Argentina, ⁶Centro Integral De Reumatologia, Tucumán, Argentina, ⁷Hospital Ángel Cruz Padilla, Tucuman, Argentina, ⁸Hospital Centro de Salud, Tucuman, Argentina
Background/Purpose: Systemic Lupus Erythematosus (SLE) is the paradigm of the autoimmune diseases that primarily affects women in a ratio of 9: 1. In England and…
Abstract Number: 1814 • 2016 ACR/ARHP Annual Meeting
Epidemiology and Microbiology of Pneumonia in Systemic Lupus Erythematosus (SLE)
Gabriela García-Guevara¹, Ricardo Ríos-Corzo², Hilda Fragoso-Loyo³, Juan Jakez-Ocampo⁴, John Hernandez-Flores², Mariana Lopez-Lopez⁵, Eduardo Carrillo-Maravilla⁶, Jose Sifuentes-Osornio² and Yemil Atisha-Fregoso⁷, ¹Internal Medicine, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico, ²Internal Medicine, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ³Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ⁴Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Mexico, ⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁶Medicina Interna, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ⁷Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
Background/Purpose: Pneumonia, remains as a main cause of mortality in patients with SLE. There are not specific guidelines for the empiric treatment in these patients.…
Abstract Number: 1842 • 2016 ACR/ARHP Annual Meeting
Pentraxin 3 Level Positively Correlated with Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus Patients
Yifang Mei, Xiaoping Sun, Yuxia Shao, Huanhuan Zhan and Zhiyi Zhang, Department of Rheumatology, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Background/Purpose: Systemic lupus erythematosus (SLE) is a kind of chronic and autoimmune disease with variable multi-system involvement of unknown causes, which is characterized by periods…
Abstract Number: 2791 • 2016 ACR/ARHP Annual Meeting
Targeting Micro-RNAs Derived from Extracellular Vesicles to Inhibit of TLR7 and TLR8 Signaling Suppresses Inflammation in a Novel Human-Mouse Chimeric Model of Systemic Lupus Erythematosus
Nicholas A. Young¹, Giancarlo R. Valiente², Holly Steigelman³, Jeffrey Hampton⁴ and Wael N. Jarjour⁵, ¹Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ²Rheumatology & Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, ³The Ohio State University, Columbus, OH, ⁴Immunology and Rheumatoloty, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Department of Rheumatology/Medicine, Ohio State University, Columbus, OH
Background/Purpose: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease displaying a heavy female predominance during reproductive years. We have previously shown that toll-like receptor…

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