ACR Meeting Abstracts

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Abstracts tagged "Synovial Immune Biology"

  • Abstract Number: 117 • 2019 ACR/ARP Annual Meeting

    The Indole Derivative NecroX Blocks Th17 Cell Differentiation and Fibroblast-like Synoviocytes-mediated Th1/Th17 Responses in Rheumatoid Arthritis

    Hyun Jung Yoo1, Shin Eui Kang 2, Ji Hye Lee 3, Ra Ham Kim 4 and Yeong-Wook Song 5, 1Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Seoul National University, Seoul, Repulbic of Korea, Seoul, Republic of Korea, 2Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea, 3Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Seoul, Republic of Korea, 4Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea, 5Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of synovium, which causes progressive joint destruction and reduction in quality of life.…
  • Abstract Number: 781 • 2019 ACR/ARP Annual Meeting

    Is down Syndrome Associated Arthritis (DA) a Distinct Disease from Juvenile Idiopathic Arthritis (JIA)?

    Charlene Foley1, Achilleas Floudas 2, Sharon Ansboro 2, Mary Canavan 2, Monika Biniecka 2, Emma Jane MacDermott 3, Ronan Mullan 4, Gerry Wilson 5, Ursula Fearon 6 and Orla Killeen 7, 1Great Ormond Street Hospital, London, Ireland, 2TBSI, Dublin, Ireland, 3OLCHC, Dublin, Ireland, 4Tallaght Hospital, Dublin, Ireland, 5UCD, Dublin, Ireland, 6TBSI, Dublin, 7National Centre for Paediatric Rheumatology (NCPR), Our Lady’s Children’s Hospital Crumlin (OLCHC), Dublin, Ireland

    Background/Purpose: Down syndrome associated Arthritis (DA) is 20 times more common than JIA. It is an erosive, polyarticular RF negative arthritis with predominance in the…
  • Abstract Number: 1985 • 2019 ACR/ARP Annual Meeting

    Divergent Mononuclear Cell Participation and Cytokine Release Profiles Define Hip and Knee Osteoarthritis

    Ricardo Grieshaber-Bouyer1, Till Kämmerer 2, Nils Rosshirt 2, Philipp Koniezke 2, Sebastien Hagmann 2, Elena Tripel 2, Johannes Kirsch 2, Tobias Gotterbarm 2 and Babak Moradi 2, 1Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; Department of Orthopedics, Heidelberg University Hospital, Heidelberg, Germany, Boston, MA, 2Department of Orthopedics, Heidelberg University Hospital, Heidelberg, Germany, Heidelberg, Germany

    Background/Purpose: Osteoarthritis (OA) is a progressive joint disease driven by a blend of inflammatory and biomechanical processes. Studies using human samples to understand inflammatory mechanisms…
  • Abstract Number: 10 • 2018 ACR/ARHP Annual Meeting

    Fibroblast like Synoviocytes (FLS) Are Capable of Inducing Phenotypical Changes Including Class Switch Recombination (CSR) in Naive B Cells, but Additional Factors Are Required to Trigger Immunoglobulin Secretion

    Dennis Bleck1, Torsten Lowin2, Matthias Schneider3 and Georg Pongratz4, 1Rheumatology Policlinic & Hiller Research Unit, Medical Faculty, University Hospital, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany, 2Department and Hiller Research Center for Rheumatology, University Hospital Duesseldorf, Duesseldorf, Germany, 3Department and Hiller Research Center for Rheumatology, Heinrich-Heine University, Duesseldorf, Germany, 4Dpt. of Rheumatology - Hiller Research Center Rheumatology, University Hospital Duesseldorf, Duesseldorf, Germany

    Background/Purpose: Rheumatoid Arthritis (RA) is a disease characterized by chronic inflammation of the synovial tissue in joints. It is driven by highly activated B cells.…
  • Abstract Number: 46 • 2018 ACR/ARHP Annual Meeting

    Organic Dust Inhalants Shift Immune Responses and Extracellular Matrix Balance between Synovium and Lung in the Collagen-Induced Arthritis Mouse Model

    Michael J. Duryee1, Jill Poole2, Amy Nelson3, Katherine Janike2, Lynell W. Klassen4, James R. O'Dell4, Bryant R. England5, Ted R. Mikuls6 and Geoffrey M. Thiele7, 1Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 2Medicine, University of Nebraska Medical Center, Omaha, NE, 3Department of Medicine, University of Nebrasa Medical Center, Omaha, NE, 4Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 5Rheumatology, VA Nebraska-Western Iowa Health Care System & University of Nebraska Medical Center, Omaha, NE, 6Internal Medicine, Division of Rheumatology, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 7University of Nebraska Medical Center, Omaha, NE

    Background/Purpose:   Emerging evidence suggests that the lungs may be an initiating site of autoimmunity leading to RA with organic inhalant exposures such as those…
  • Abstract Number: 928 • 2018 ACR/ARHP Annual Meeting

    Single Cell RNA-Sequencing of Rheumatoid Synovial Fibroblasts Reveals a Disease-Associated Spatial Gradient Modulated By Inductive Notch Signaling

    Kevin Wei1, Ilya Korsunsky2, Jennifer Marshall3, Gerald Watts4, Anqi Gao5, Philip Blazar6, Jeffrey Lange6, Thomas Thornhill6, Chris Buckley7, Soumya Raychaudhuri8 and Michael Brenner9, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 4Brigham and Women's Hospital, Boston, MA, 5Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 6Orthopaedic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 7University of Birmingham, Birmingham, United Kingdom, 8Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA, 9Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: In rheumatoid arthritis (RA), tissue resident fibroblasts orchestrate chronic inflammation and regulate pathologic bone and cartilage remodeling that causes irreversible joint damage. Recently, we…
  • Abstract Number: 1045 • 2018 ACR/ARHP Annual Meeting

    The Coll2-1 Peptide of Collagen Type II: A New Actor of Synovitis in Osteoarthritis

    Cécile Lambert1, Didier Borderie2, Jean-Emile Dubuc3, François Rannou2 and Yves Henrotin4,5, 1Bone and Cartilage Research Unit, University of Liege, Liege, Belgium, 2Inserm umr 1124, Laboratory of pharmacology, toxicology and cell signaling, University Paris Descartes, Paris, France, 3Orthopaedic Department, University Clinics St Luc, Brussels, Belgium, 4Physical Therapy and Rehabilitation, Princess Paola Hospital, Marche-en-Famenne, Belgium, 5Bone and Cartilage Research Unit, University of Liege, Liège, Belgium

    Background/Purpose: We evaluated the inflammatory effect of Coll2-1 peptide in osteoarthritic synoviocytes and rats by comparing peptide-induced inflammatory reaction with the one induced by bovine…
  • Abstract Number: 1053 • 2018 ACR/ARHP Annual Meeting

    Synovial Inflammation Identifies Patients Clusters in Osteoarthritis

    Hannah Labinsky1, Paul Panipinto1, Kaytlyn Ly2, Deric Khuat2, Bhanupriya Madarampalli3, Vineet Mahajan1, Jonathan Clabeaux4, Kevin MacDonald4, Peter Verdin4, Jane H. Buckner2 and Erika H. Noss3, 1Medicine, Division of Rheumatology, University of Washington, Seattle, WA, 2Benaroya Research Institute at Virginia Mason, Seattle, WA, 3Rheumatology, University of Washington, Seattle, WA, 4Orthopedics, Virginia Mason Hospital, Seattle, WA

    Background/Purpose: Synovial membrane inflammation is common in osteoarthritis (OA). Inflammation may be present at all disease stages, increases the risk of cartilage injury, and is…
  • Abstract Number: 1078 • 2018 ACR/ARHP Annual Meeting

    Standardization of Synovial Biopsies Procedures across Centers: A Consensus Initiative Using a Delphi Survey

    Aurélie Najm1,2, Benoît Le Goff MD PhD3,4, Carl Orr5, Rogier Thurlings6, Juan D. Cañete7, Frances Humby8, Stefano Alivernini9, Søren Andreas Just10, Vasco C. Romão11, Veit Krenn12, Ulf Müller-Ladner13, Olga Addimanda14, Antonio Manzo15, Sander W. Tas16, Patrick Durez17, Laurent Meric de Bellefon17, Maria Stoenoiu18, Vibeke Strand19, Mihir D Wechalekar20, João E. Fonseca21, Bernard R. Lauwerys22 and Douglas J. Veale23, 1INSERM U1238 University of medicine, PHY-OS Laboratory, Nantes, France, 2Department of Rheumatology, Nantes University Hospital, Nantes, France, 3Rheumatology, Nantes University Hospital, Nantes, France, 4UNR1238 University of medicine, PHY-OS Laboratory, Nantes, France, 5Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin 4, Ireland, 6Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 7Rheumatology Deparment, Hospital Clinic and IDIBAPS, Barcelona, Spain, Barcelona, Spain, 8Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 9Division of Rheumatology - Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, 10Department of Rheumatology, Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, 11Rheumatology Department, Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, CHLN, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 12Zytologie und Molekulare Diagnostik, MVZ-Zentrum für Histologie, Trier, Germany, 13Dept. of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Germany, Bad Nauheim, Germany, 14Medicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, Bologna, ., Italy, 15Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico San Matteo Foundation/University of Pavia, Pavia, Italy, 16Clinical Immunology & Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 17Rheumatology, Rheumatology - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, 18Rheumatology - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Bruxelles, Belgium, 19Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 20Royal Adelaide Hospital, Adelaide, Australia, 21Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, CHLN, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 22Department of Rheumatology, Rheumatology - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, 23Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin, Ireland

    Background/Purpose: Synovial biopsies are increasingly performed in both clinical setting and translational research. Synovial tissue analysis role in prediction of response to treatment is to…
  • Abstract Number: 1981 • 2018 ACR/ARHP Annual Meeting

    A Molecular Bayesian Network for Rheumatoid Arthritis Reveals Multiple Candidate Key Regulators for Disease Severity

    Wenhui Wang1, Amit Lahiri2, Teresina Laragione2, Jun Zhu1 and Percio S. Gulko2,3, 1Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, 2Medicine/Rheumatology, Icahn School of Medicine at Mount Sinai, New York, NY, 3Icahn School of Medicine at Mount Sinai, New York, NY

    Background/Purpose: Rheumatoid arthritis (RA) is a common and chronic autoimmune joint disease. RA is pathologically heterogeneous with multiple contributing factors. While there has been a…
  • Abstract Number: 2024 • 2018 ACR/ARHP Annual Meeting

    Comparison of B and T Cell Subsets, Cytokine Expression and Synovial Pathology in Down’s Arthritis (DA) and Juvenile Idiopathic Arthritis (JIA)

    Charlene Foley1, Achilleas Floudas2, Mary Canavan2, Monika Biniecka2, Emma-Jane MacDermott3, Orla G Killeen3, Ronan Mullan4 and Ursula Fearon5, 1Our Lady's Children's Hospital Crumlin, National Centre for Paediatric Rheumatology, Dublin, Ireland, 2Trinity Biomedical Sciences Institute, Dublin, Ireland, 3National Centre for Paediatric Rheumatology, Dublin, Ireland, 4Rheumatology, Tallaght Hospital, Dublin, Ireland, 5Trinity College Dublin, Trinity Biomedical Sciences Institute, Dublin, Ireland

    Background/Purpose: Down syndrome (DS) is a common chromosomal disorder associated with a range of medical & immune abnormalities e.g. increased susceptibility to infections & a…
  • Abstract Number: 2060 • 2018 ACR/ARHP Annual Meeting

    Comparative Histologic and Molecular Analysis of Synovial Tissue in Early Treatment-Naïve Psoriatic and Rheumatoid Arthritis

    Alessandra Nerviani1, Frances Humby1, Gloria Lliso Ribera1, Wang Sin Tan1, Marie Astrid Boutet1, Katriona Goldmann1, Fabiola Bene1, Rebecca Hands1, Stephen Kelly2, Michele Bombardieri3, Myles J. Lewis3, Chris Buckley4, Peter C. Taylor5, Iain B. McInnes6 and Costantino Pitzalis1, 1Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 2Rheumatology Department, Barts Health NHS Trust, London, London, United Kingdom, 3Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, United Kindgdom, London, United Kingdom, 4Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham, United Kingdom, 5University of Oxford Botnar Research Centre, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 6Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA) are chronic joint conditions characterised by persistent inflammation of the synovial tissue (ST). Previous reports suggested less…
  • Abstract Number: 1339 • 2017 ACR/ARHP Annual Meeting

    Role of Hexokinase-2 in Synovial Lining Hypertrophy in Murine Arthritis

    Marta Fernandez Bustmanate1, Jeffrey Smith2, Adam Paul Croft3, Gary S. Firestein4, Chris Buckley5, Shigeki Miyamoto2 and Monica Guma6, 1Medicine, UCSD, San Diego, CA, 2Pharmacology, UCSD, La Jolla, CA, 3Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 4Medicine, University of California San Diego, La Jolla, CA, 5University of Birmingham, Birmingham, United Kingdom, 6Medicine, UCSD, La Jolla, CA

    Background/Purpose: Recent studies indicate that fibroblast-like synoviocyte (FLS) glucose metabolism is altered in rheumatoid arthritis (RA). Hexokinases (HKs) catalyze the first step in glucose metabolism.…
  • Abstract Number: 1405 • 2017 ACR/ARHP Annual Meeting

    Using Flow and Mass Cytometry to Demonstrate Robust Tissue Processing to Query Molecular Heterogeneity in Phase 1 of the Accelerating Medicines Partnership (AMP) – RA Network

    Kevin Wei1, Deepak Rao2, Fan Zhang3, Chamith Fonseka3, Kamil Slowikowski3, Joshua Keegan4, Laura T. Donlin5, Jason Turner6, Mandy J. McGeachy7, Nida Meednu8, David Lieb9, Stephen Kelly10, Susan M. Goodman11, David L. Boyle12, William H. Robinson13, Paul J. Utz14, Gary S. Firestein15, Harris Perlman16, Edward F. DiCarlo17, Costantino Pitzalis10, Andrew Filer18, Brendan Boyce19, Ellen M. Gravallese20, Chad Nusbaum21, James Lederer4, Nir Hacohen22,23,24, Peter Gregersen25, Larry W. Moreland26, Michael Holers27, Vivian P. Bykerk28, Soumya Raychaudhuri3, Michael Brenner29 and Jennifer H. Anolik8, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Divisions of Genetics and Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 6Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 7Medicine, University of Pittsburgh, Pittsburgh, PA, 8Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, 9Broad Institute, Cambridge, MA, 10Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London, School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 11Medicine, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 12University of California San Diego, La Jolla, CA, 13Stanford University School of Medicine, Stanford, CA, 14Medicine, Stanford University School of Medicine, Stanford, CA, 15Medicine, University of California San Diego, La Jolla, CA, 16Department of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Northwestern University Feinberg School of Medicine,, Chicago, IL, 17Laboratory Medicine, Hospital for Special Surgery, New York, NY, 18Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham, United Kingdom, 19University of Rochester Medical Center, Rochester, NY, 20Lazare Research Bldg, University of Massachusetts Medical School, Worcester, MA, 21The Broad Institute and Harvard, Cambridge, MA, 22Harvard Medical School, Boston, MA, 23Massachusetts General Hospital, Charlestown, MA, 24Broad Institute of MIT and Harvard, Cambridge, MA, 25The Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY, 26Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 27Medicine, Division of Rheumatology, University of Colorado Denver, Aurora, CO, 28Divison of Rheumatology, Hospital for Special Surgery, New York, NY, 29Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Discovery and application of new therapies for rheumatoid arthritis (RA) has been hampered by multiple factors, including disease heterogeneity and the lack of well…
  • Abstract Number: 1406 • 2017 ACR/ARHP Annual Meeting

    Methods for Generating Multiple High-Dimensional Analyses of Cryopreserved Synovial Tissue Developed By the Accelerating Medicines Partnership RA/SLE Network

    Deepak Rao1, Laura T. Donlin2, Kevin Wei3, Nida Meednu4, Jason Turner5, Mandy J. McGeachy6, Fumitaka Mizoguchi7, Joshua Keegan8, James Lederer9, Maria Gutierrez-Arcelus10, Kamil Slowikowski11, Kaylin Muskat12, Joshua Hillman12, Cristina Rozo13, Edd Ricker14, Thomas Eisenhaure15, David Lieb15, Shuqiang Li15, Edward Browne15, Chad Nusbaum15, William H. Robinson16, Stephen Kelly17, Alessandra B. Pernis18, Lionel Ivashkiv19, Susan M. Goodman20, Ellen M. Gravallese21, Michael Holers22, Nir Hacohen23, Costantino Pitzalis17, Peter Gregersen24, Vivian P. Bykerk25, Larry W. Moreland26, Gary Firestein27, Soumya Raychaudhuri28, Andrew Filer29, David L. Boyle30, Michael Brenner10 and Jennifer H. Anolik4, 1Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 3Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, 5Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 6Medicine, University of Pittsburgh, Pittsburgh, PA, 7Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 8Brigham and Women's Hospital, Boston, MA, 9Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 10Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 11Division of Medicine and Rheumatology, Brigham and Women's Hospital, Harvard Medical Schoo, Boston, MA, 12University of California, San Diego, San Diego, CA, 13Hospital for Special Surgery, New York, NY, 14Weill Cornell Graduate School of Medical Sciences, New York, NY, 15Broad Institute, Cambridge, MA, 16Stanford University School of Medicine, Stanford, CA, 17Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London, School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 18David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 19Medicine, Hospital for Special Surgery, New York, NY, 20Medicine, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 21Lazare Research Bldg, University of Massachusetts Medical School, Worcester, MA, 22Medicine, Division of Rheumatology, University of Colorado Denver, Aurora, CO, 23Harvard Medical School, Boston, MA, 24The Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY, 252-005, Mt Sinai Hospital, Toronto, ON, Canada, 26Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 27EGG, St Cloud, France, 28Division of Medicine and Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 29Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham, United Kingdom, 30University of California San Diego, La Jolla, CA

    Background/Purpose: Detailed analyses of cells from rheumatoid arthritis (RA) synovium may identify cell phenotypes and functions that drive tissue pathology and joint damage. The AMP…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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