Abstracts tagged "synovial fluid and tocilizumab"

Abstract Number: 577 • 2016 ACR/ARHP Annual Meeting
TCZ Modulates the Production of Ccfdna Derived from RA Synovial Cells
Naonori Hashimoto¹, Kohsuke Yoshida¹, Teppei Hashimoto², Ayako Nakai¹, Kenta Kaneshiro¹, Kohjin Suzuki¹, Yoshiko Kawasaki², Nao Shibanuma³, Natsuko Nakagawa⁴, Yoshitada Sakai⁵ and Akira Hashiramoto⁶, ¹Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan, ²Department of Rheumatology, Kobe Kaisei Hospital, Kobe, Japan, ³Departmant of Orthopaedic Surgery, Kobe Kaisei Hospital, Kobe, Japan, ⁴Department of Orthopaedic Surgery, Konan-Kakogawa Hospital, Kakogawa, Japan, ⁵Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine, Kobe, Japan, ⁶Department of Biophysics, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan
Background/Purpose: DNA is fragmented and released into blood circulation as a circulating cell-free DNA (ccfDNA) because of damage or death of cells. Although the…
Abstract Number: 938 • 2013 ACR/ARHP Annual Meeting
A Disintegrin and Metalloprotease-17 (ADAM-17) Is Expressed In Rheumatoid Arthritis and Mediates Monocyte Migration
Takeo Isozaki¹, Nao Oguro², Shinya Seki¹, Yoko Miura¹, Sho Ishii¹, Hiroyuki Tsukamoto¹, Takahiro Tokunaga¹, Masayu Umemura¹, Hidekazu Furuya¹, Ryo Yanai¹, Sakiko Isojima¹, Kuninobu Wakabayashi¹, Nobuyuki Yajima¹, Yusuke Miwa¹ and Tsuyoshi Kasama¹, ¹Div of Rheumatology, Showa University School of Med, Shinagawa-ku Tokyo, Japan, ²Div of Rhemuatology, Showa University School of Med, Shinagawa-ku Tokyo, Japan
Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized byinflammation and joint destruction. Migration of monocytes/macrophages into the synovium is important in a variety…

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