Abstracts tagged "spondyloarthritis"

Abstract Number: 0548 • ACR Convergence 2020
Incidence of First Cardiovascular Event in Spanish Patients with Chronic Inflammatory Rheumatic Diseases. Prospective Data After Five Years of Follow Up
Maria Auxiliadora Martin-Martinez¹, Santos Castañeda², Fernando Sanchez-Alonso³, Carmen García-Gómez⁴, Carlos González_Juanatey⁵, M. Ángeles Belmonte-López⁶, Jesus Tornero-Molina⁷, José Santos-Rey⁸, Carmen Olga Sánchez-González⁹, Estefania Moreno¹⁰, Maria del puerto Moreno-Gil¹¹, Tatiana Cobo-Ibañez¹², Jose Antonio Pinto-Tasende¹³, Jesús Babío-Herráez¹⁴, Gema Bonilla¹⁵, Antonio Juan-Mas¹⁶, Francisco Manero-Ruiz¹⁷, Montserrat Romera-Baurés¹⁸, Javier Bachiller-Corral¹⁹, Eugenio Chamizo-Carmona²⁰, Javier Calvo-Catalán²¹, Raimon Sanmartí²², Celia Erausquin-Arruabarrena²³, Rosario Garcia-Vicuña²⁴, Carmen Barbadillo²⁵, Sergio Ros-Expósito²⁶, Ana Isabel Turrión²⁷, M José González-Fernández²⁸, Jose Miguel Senabre²⁹, Silvia Martínez-Pardo³⁰, Ana Ruibal-Escribano³¹, Emilio Giner-Serret³², Elisabet Berzosa-Sola³³, Julia Martínez-Barrio³⁴, Encarnación Pagán³⁵, M Enriqueta- Peiró³⁶, Sagrario Bustabad-Reyes³⁷, Alba Erra-Durán³⁸, Beatriz González Álvarez³⁹, Ana Cruz Valenciano⁴⁰, Javier Rivera-Redondo⁴¹, Manuel Moreno Ramos⁴², Sergio Rodriguez Montero⁴³, Mercedes Morcillo-Valle⁴⁴, Maria Teresa Navío⁴⁵, Maria Galindo-Izquierdo⁴⁶, Manuel Riera-Soler⁴⁷, Jordi Fiter⁴⁸, Javier Llorca⁴⁹ and Miguel Ángel González-Gay⁵⁰, ¹Spanish Society of Rheumatology, Madrid, Spain, ²Princesa University Hospital, Universidad Autónoma, Madrid, Madrid, Spain, ³Biobadaser, Research Unit, Sociedad Española de Reumatología, Madrid, Spain, ⁴Consorci Sanitari de Terrassa, Barcelona, Spain, ⁵Hospital Lucus Augusti, Lugo, Spain, ⁶Hospital Regional Universitario Carlos Haya, Malaga, Spain, ⁷University Hospital of Guadalajara. Spain, Madrid, Madrid, Spain, ⁸Hospital Virgen de la Salud, Toledo, Spain, ⁹Hospital Sureste, Madrid, Spain, ¹⁰Universitario Vall D'hebron, Barcelona, Spain, ¹¹Complejo Hospitalario de Cáceres, Caceres, Spain, ¹²Hospital Infanta Sofia, Madrid, Spain, ¹³CHUAC, A Coruña, Spain, ¹⁴Hospital de Cabueñes, Gijón, Spain, ¹⁵Rheumatology, La Paz University Hospital-IdiPAZ, Madrid, Spain, ¹⁶Hospital Sont Llatzer, Palma de Mallorca, Spain, ¹⁷Hospital Universitario Miguel Servet, Zaragoza, Spain, ¹⁸Hospital Universitario de Bellvitge, Barcelona, Spain, ¹⁹Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, ²⁰Hospital de Merida, Badajoz, Spain, ²¹Hospital General Universitario Valencia, Valencia, Spain, ²²Hospital Universitari Clínic de Barcelona, Barcelona, Catalonia, Spain, ²³Hospital de Gran Canaria Dr. Negrín, Gran Canaria, Spain, ²⁴Hospital Universitario de la Princesa, IIS-Princesa, UAM, Madrid, Madrid, Spain, ²⁵Hospital Universitario Puerta de Hierro, Madrid, Spain, ²⁶Hospital Viladecans, Barcelona, Spain, ²⁷Hospital Universitario de Salamanca, Salamanca, Spain, ²⁸Hospital Dexeus, Barcelona, Spain, ²⁹Hospital de Marina Baixa, Alicante, Spain, ³⁰H. Mutua de Terrassa, Barcelona, Catalonia, Spain, ³¹Hospital Alfredo Espinosa, Urduliz, Pais Vasco, Spain, ³²Hospital Obispo Polanco, Teruel, Spain, ³³Hospital del Elda, Alicante, Spain, ³⁴Hospital General Universitario Gregorio Marañón, Madrid, ³⁵Hospital Los Arcos, Murcia, Spain, ³⁶Hospital Marques de Valdecilla, Santander, Spain, ³⁷Hospital Universitario Canarias, Tenerife, Spain, ³⁸Hospital San Rafael, Barcelona, Spain, ³⁹Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain, ⁴⁰Hospital Severo Ochoa, Madrid, Spain, ⁴¹Instituto Provincial de Rehabilitación, Madrid, Spain, ⁴²Hospital Virgen de la Arrixaca, Murcia, Spain, ⁴³H. Virgen de Valme, Sevilla, Spain, ⁴⁴Hospital El Escorial, Madrid, Spain, ⁴⁵Hospital Infanta Leonor, Madrid, Spain, ⁴⁶Hospital Universitario 12 de Octubre, Madrid, Spain, ⁴⁷Hospital dos de Maig, Barcelona, Spain, ⁴⁸Hospital Universitario Son Dureta, Palma de Mallorca, Spain, ⁴⁹School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, ⁵⁰Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain
Background/Purpose: To determine the incidence and risk factors implicated in the development of first cardiovascular (CV) event (CVE) in patients with chronic inflammatory rheumatic diseases…
Abstract Number: 0998 • ACR Convergence 2020
Differential Roles of TNFRI and TNFRII in the Morphology of Secondary Lymphoid Organs
Kim Jeucken¹, Jan Piet van Hamburg¹ and Sander Tas², ¹Amsterdam Rheumatology and Immunology Center (ARC), Department of Rheumatology and Clinical Immunology, Department of Experimental Immunology and Amsterdam Infection and Immunity Institute, Amsterdam UMC; location AMC, University of Amsterdam, Netherlands, Amsterdam, Netherlands, ²Amsterdam Rheumatology and Immunology Center (ARC), Department of Rheumatology and Clinical Immunology, Department of Experimental Immunology and Amsterdam Infection and Immunity Institute, Amsterdam UMC; location AMC, University of Amsterdam, Netherlands, Utrecht, Netherlands
Background/Purpose: Tumour necrosis factor (TNF) induced signaling events are important in lymphoid organ development and function, both in health and in immune-mediated inflammatory diseases such…
Abstract Number: 1324 • ACR Convergence 2020
Risk Factors for Adverse Pregnancy Outcomes in Women with Spondyloarthritis: An Observational Study from Two European Multidisciplinary Pregnancy Clinics
Ana Rita Cruz-Machado¹, Francesca Crisafulli², Sofia Barreira³, Patricia Martins⁴, Maria Chiara Gerardi⁵, Matteo Filippini², Micaela Fredi², Roberto Gorla⁶, Maria Grazia Lazzaroni², Cecilia Nalli⁶, Marco Taglietti², Andrea Lojacono⁷, Sonia Zatti⁸, Monica Centeno⁹, Cláudia Araújo¹⁰, Luísa Pinto¹⁰, Franco Franceschini¹¹, Angela Tincani¹², Susana Capela¹ and Laura Andreoli², ¹Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal, ²Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, ³Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal, ⁴Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universit�rio Lisboa Norte - Hospital de Santa Maria, Set�bal, Portugal, ⁵Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Milano, Italy, ⁶Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Italy, ⁷Obstetrics and Gynaecology, Spedali Civili and University of Brescia, Brescia, Italy, ⁸Obstetrics and Gynecology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, ⁹Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução, Hospital de Santa Maria, CHULN, Lisbon, Portugal, ¹⁰Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução, Hospital de Santa Maria, CHULN, Lisboa, Portugal, ¹¹Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, ¹²Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Milano, Italy
Background/Purpose: Women with Spondyloarthritis (SpA) seem at increased risk for adverse pregnancy outcomes (APO), however limited data have been published so far. The aim of…
Abstract Number: 1375 • ACR Convergence 2020
Remission in Axial Spondyloarthritis: Is There a Difference Between NSAIDs and Biologics in the Real Life?
Charlotte Baert¹, Charlene Mouafo Toukam², Tatiana Sokolova³, Maria S. Stoenoiu⁴, Patrick Durez⁵, Laurent Meric De Bellefon² and Adrien Nzeusseu Toukap⁶, ¹Rheumatology department, St-Luc university hospitals, Brussels, Belgium, ²Rheumatology department; St-Luc University Hospitals, Brussels, Belgium, ³Rheumatology, Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCL) – Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, ⁴1Department of Rheumatology, Cliniques Universitaires Saint-Luc, 2Institut de recherche expérimentale et cliniques (IREC), Brussels, Belgium, ⁵Division of Rheumatology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium, ⁶1Department of Rheumatology, Cliniques Universitaires Saint Luc, 2Institut de recherche expérimentale et clinique (IREC), Brussels, Belgium
Background/Purpose: Randomized-controlled trials (RCTs) done in axial spondyloarthritis (AxSpA) patients have shown that remission in Ankylosing Spondylitis and nonradiographic AxSpA patients treated without biologics (BIOL)…
Abstract Number: 1857 • ACR Convergence 2020
KIR3DL2 Is Not Overexpressed on CD4+ T Cells and NK Cells in Patients with Axial Spondyloarthritis csDMARD and bDMARD Naive
Guillaume Larid¹, Sophie Trijau¹, Clothilde Barral¹, Pierre Lafforgue¹ and Thao Pham², ¹Aix Marseille Univ, APHM, Rheumatology department, Marseille, France, ²Aix Marseille Univ, APHM, department of rheumatology, Marseille, France
Background/Purpose: Overexpression of KIR3DL2 on CD4+ T-cells and NK-cells has been reported in patients with ankylosing spondylitis (AS) HLAB27+. We aimed to 1) analyse KIR3DL2…
Abstract Number: 1884 • ACR Convergence 2020
Disease Activity in an Axial Spondyloarthritis Cohort During the COVID-19 Pandemic
Jean Liew¹, Maria Castillo², Ethan Zaccagnino², Patricia Katz³, Nigil Haroon⁴ and Lianne Gensler⁵, ¹University of Washington, Seattle, WA, ²UCSF, San Francisco, CA, ³University of California, San Francisco, Novato, CA, ⁴University of Toronto, Toronto, ON, Canada, ⁵University of California San Francisco, San Francisco, CA
Background/Purpose: Response to the global coronavirus disease (COVID-19) pandemic has resulted in shelter-in-place orders and major changes to how people go about their daily lives.…
Abstract Number: 2019 • ACR Convergence 2020
Preliminary Definition of a Positive MRI for Active Lesions in the Sacroiliac Joints Typical of Axial Spondyloarthritis
Walter Maksymowych¹, Xenofon Baraliakos², Ulrich Weber³, Pedro M Machado⁴, Susanne J Pedersen⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁷, Martin Rudwaleit⁸, Désirée van der Heijde⁹, Robert Landewé¹⁰, Joel Paschke¹¹, Mikkel Østergaard¹² and Robert G Lambert¹³, ¹University of Alberta, Edmonton, AB, Canada, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ³University of South Denmark, Odense, Denmark, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet University, Copenhagen, Denmark, ⁶Charité Universitätsmedizin Berlin, Berlin, Germany, ⁷Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁸Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany, ⁹Leiden University Medical Center, Leiden, Netherlands, ¹⁰Amsterdam University Medical Center & Zuyderland Hospital, Amsterdam, Netherlands, ¹¹CARE Arthritis, Edmonton, AB, Canada, ¹²Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ¹³University of Alberta and CARE Arthritis, Edmonton, AB, Canada
Background/Purpose: The ASAS definition of a positive MRI for inflammation (ASAS-MRI+) is intended for classification of patients as having axSpA but is often misused for…
Abstract Number: 0238 • ACR Convergence 2020
Gestational Desire and Certolizumab Pegol in Patients with Chronic Inflammatory Rheumatic Disease. Preliminary Results of the GESTAMAD Cohort
Laura Gonzalez Hombrado¹, Marina Salido Olivares², Maria Carmen Ortega de la O³, Pilar Navarro Alonso⁴, Patricia Castro Perez⁵, Ana Castilla⁶, Alvaro Garcia Martos⁷, Celia Arconada³, Angel Aragon Diez⁸, Carolina Marin huertas³ and Eva Maria Andres Esteban⁹, ¹Hospital Universitario del Tajo, MADRID, Spain, ²Hospital de Parla, Madrid, Spain, ³Hospital infanta Elena, Madrid, Spain, ⁴Hospital de Fuenlabrada, Madrid, Madrid, Spain, ⁵Hospital Universitario de Getafe, Madrid, Spain, ⁶Hospital Universitario La Paz, Madrid, Spain, ⁷Hospital Universitario del Tajo, Madrid, ⁸Hospital Universitario de Gerafe, Madrid, Spain, ⁹Rey Juan Carlos University, Madrid, Spain
Background/Purpose: INTRODUCTION The use of biological therapies during pregnancy has been contraindicated since the beginning of the use of these drugs. In recent years several…
Abstract Number: 0630 • ACR Convergence 2020
“No Benefit from a Strict Immobilization in Vertebral Osteomyelitis” Vertebral Immobilization and Neurological Complication in Acute Pyogenic Vertebral Osteomyelitis: SPONDIMMO, a Prospective Cohort of 250 Patients
Adrien Le Pluart¹, COIFFIER Guillaume², Christelle Darrieutort¹, CORMIER Grégoire³, GODOT Sophie⁴, Sebastien Ottaviani⁵, Gaetane Nocturne⁶, MEROT Oriane⁷, COUDERC Marion⁸, HOPPE Emmanuel⁹, MULLEMAN Denis¹⁰, Benoit Le Goff¹¹ and Geraldine Bart¹², ¹Nantes University Hospital Center, Nantes, France, ²Rennes University Hospital Center, Rennes, France, ³La Roche Sur Yon Hospital Center, La Roche Sur Yon, France, ⁴Paris Croix Saint Simon Hospital Center, Paris, France, ⁵Rheumatology Department, Bichat hospital, APHP, Paris, France, ⁶Rheumatology Department, Bicetre Hospital, APHP, France, Le Kremlin-Bicêtre, France, ⁷Saint Nazaire Hospital Center, Saint-Nazaire, Pays de la Loire, France, ⁸Clermont Ferrant University Hospital Center, Clermont Ferrand, France, ⁹Angers University Hospital Center, Angers, France, ¹⁰Tours University Hospital Center, Tours, France, ¹¹Nantes University Hospital, Nantes, Pays de la Loire, France, ¹²Rennes University Hospital Center, Rennes, Bretagne, France
Background/Purpose: Vertebral osteomyelitis (VO) can be associated with neurological complications. We showed in a previous study that they occurred in 40% of patients with VO.…
Abstract Number: 1028 • ACR Convergence 2020
Probabilistic Linkage of a Cohort of Individuals with Symptoms Suggestive of Early Spondyloarthritis and the French National Healthcare Database
Aya Ajrouche¹, Candice Estellat¹, Clementina Lopez-Medina², Anna Molto³, Adeline Ruyssen Witrand⁴, Pascal Claudepierre⁵, Florence Tubach⁶, Laure Gossec⁷ and Maxime Dougados⁸, ¹AP-HP, Hôpital Pitié-Salpêtrière, Département Santé Publique, Centre de Pharmacoépidémiologie (Cephepi), Sorbonne Université, INSERM, Institut Pierre Louis d’Epidémiologie et de Santé Publique, équipe PEPITES, CIC 1901, F75013, Paris, France, Paris, France, ²Rheumatology Department, Cochin Hospital, Paris, Paris, France, ³Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France, ⁴Rheumatology center, University Hospital of Toulouse, Inserm 1027, University Paul Sabatier, Toulouse, France, Toulouse, France, ⁵Hôpital Henri Mondor, Université Paris Est Créteil, EA 7379 EpiDermE, department of rheumatology, Créteil, France, ⁶Pierre Louis Institute of Epidemiology and Public Health, INSERM 1136, Sorbonne University and Centre of Pharmacoepidemiology, Pitié Salpêtrière Hospital, APHP.Sorbonne University, Paris, Ile-de-France, France, ⁷Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, ⁸Université de Paris, Department of Rheumatology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France
Background/Purpose: DESIR is the French cohort of patients with symptoms suggestive of early axial Spondyloarthritis (axSpA). Our objective was to enrich this cohort with claims…
Abstract Number: 1327 • ACR Convergence 2020
Comorbidity Burden in Patients with Non-Radiographic Axial Spondyloarthritis at Least as High as in Ankylosing Spondylitis
Jonas Sagard¹, Elisabet Lindqvist², Elisabeth Mogard¹, Anna Jöud³, Mats Geijer⁴, Tor Olofsson¹ and Johan K. Wallman¹, ¹Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital, Lund, Sweden., Lund, Sweden, ²Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital. Lund, Sweden, Lund, Sweden, ³Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, Sweden., Lund, Sweden, ⁴Department of Radiology, Institute of Clinical Sciences, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden. Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Gothenburg, Sweden
Background/Purpose: Few studies have investigated the overall occurrence of comorbidities in patients with non-radiographic axial spondyloarthritis (nr-axSpA) in relation to ankylosing spondylitis (AS). Compared to…
Abstract Number: 1376 • ACR Convergence 2020
Impact of Body Composition Measures on the Response to Biological Disease-modifying Anti-rheumatic Drugs in Patients with Ankylosing Spondylitis
Valeria Rios Rodriguez¹, Mikhail Protopopov¹, Fabian Proft¹, Judith Rademacher¹, Burkhard Muche¹, Anne-Katrin Weber¹, Susanne Lüders¹, Hildrun Haibel¹, Maryna Verba¹, Joachim Sieper¹ and Denis Poddubnyy², ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Data on the impact of body weight and body mass index (BMI) on the response to biological disease-modifying anti-rheumatic drugs (bDMARDs) in axial spondyloarthritis…
Abstract Number: 1858 • ACR Convergence 2020
Increased Proportion of TH17, TH22 and TC17 Cells and the Correlation to IL-22 and Clinical Parameters in Patients with Ankylosing Spondylitis from Northern Sweden
Kristina Lejon¹, Urban Hellman², Lan Do², Anjani Kumar² and Helena Forsblad-d'Elia³, ¹Department of Clinical microbiology, Infection and Immunology, Umeå University, Umeå, Sweden, ²Department of Public Health and Clinical Medicine, Rheumatology, Umeå, Sweden, ³Department of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Vasterbottens Lan, Sweden
Background/Purpose: Increased levels of TH17 and TH22 as well as TC17 and TC22 cells have previously been associated with ankylosing spondylitis (AS). The correlation between…
Abstract Number: 1887 • ACR Convergence 2020
Spinal Mobility and Function: How Closely Do They Associate in Axial Spondyloarthropathy?
Sinead Maguire¹, Phil Gallagher² and Finbar O'Shea¹, ¹St James' Hospital, Dublin, Ireland, ²St Vincents University Hospital, UCD, Dublin, Ireland
Background/Purpose: Axial spondyloarthropathy (axSpA) is a form of inflammatory arthritis affecting the axial skeleton. Persistent disease activity can result in restricted spinal mobility over time,…
Abstract Number: 2020 • ACR Convergence 2020
Preliminary Definition of a Positive MRI for Structural Lesions in the Sacroiliac Joints in Axial Spondyloarthritis
Walter Maksymowych¹, Xenofon Baraliakos², Ulrich Weber³, Pedro M Machado⁴, Susanne J Pedersen⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁷, Martin Rudwaleit⁸, Désirée van der Heijde⁹, Robert Landewé¹⁰, Joel Paschke¹¹, Robert G Lambert¹² and Mikkel Østergaard¹³, ¹University of Alberta, Edmonton, AB, Canada, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ³University of South Denmark, Odense, Denmark, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet University, Copenhagen, Denmark, ⁶Charité Universitätsmedizin Berlin, Berlin, Germany, ⁷Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁸Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany, ⁹Leiden University Medical Center, Leiden, Netherlands, ¹⁰Amsterdam University Medical Center & Zuyderland Hospital, Amsterdam, Netherlands, ¹¹CARE Arthritis, Edmonton, AB, Canada, ¹²University of Alberta and CARE Arthritis, Edmonton, AB, Canada, ¹³Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: There is lack of international consensus as to what defines a structural lesion on MRI of the sacroiliac joints (SIJ) typical of axial spondyloarthritis…

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