Abstracts tagged "spondylarthritis and spondylarthropathy"

Abstract Number: 216 • 2019 ACR/ARP Annual Meeting
Does Fibromyalgia Change the Evaluation of Spondyloarthritis Activity? A Meta-analysis of Observational Studies
Arthur Beck¹, Lilian SOLE ¹, Thomas Barnetche ² and Pascale Vergne-Salle ¹, ¹CHU de LIMOGES, LIMOGES, France, ²CHU de BORDEAUX, BORDEAUX, France
Background/Purpose: Recent studies evaluated the prevalence of Fibromyalgia (FM) in Spondyloarthritis (SpA) and its impact on disease activity scores, but none meta-analysis exists yet. Therefore,…
Abstract Number: 1593 • 2018 ACR/ARHP Annual Meeting
Extra-Articular Manifestations, Neoplasms and Cardiovascular Events in a Series of Spondyloarthritis from a Single Center
Itziar Calvo Zorrilla¹, Edurne Guerrero Basterretxea¹, Oihane Ibarguengoitia¹, David Montero¹, Maria Luz Garcia Vivar¹, Esther Ruíz Lucea², Ignacio Torre Salaberri², Olaia Begoña Fernandez Berrizbeitia², Juan Maria Blanco Madrigal², Ana Rosa Inchaurbe Pellejero¹, Clara Eugenia Perez Velasquez², Natalia Rivera-García³, Maria Jesus Allande Lopez Linares³, Iñigo Gorostiza-Hormaetxe⁴ and Eva Galíndez Agirregoikoa², ¹Rheumatology, Rheumatology Department; Basurto University Hospital, Bilbao, Spain, ²Rheumatology Department; Basurto University Hospital, Bilbao, Spain, ³Rheumatology, University Hospital of Basurto, Bilbao, Spain, ⁴Research Department, Basurto University Hospital, Bilbao, Spain
Background/Purpose: Spondyloarthritis(SpA) is characterized by axial, peripheral and extra-articular manifestation(EAMs). Its frequency depends on the series, being the psoriasis(Ps), uveitis and inflammatory bowel disease(IBD) the…
Abstract Number: 1611 • 2018 ACR/ARHP Annual Meeting
Hospitalizations for Serious Infections in Psoriatic Arthritis Patients: Data from the National Inpatient Sample 2000-2014
Paras Karmacharya¹, Cynthia S. Crowson², Dilli Poudel³, Pragya Shrestha⁴ and Kerry Wright⁵, ¹Division of Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Internal Medicine, Reading Hospital-Tower Health System, WEST READING, PA, ⁴Internal medicine, Reading Hospital-Tower Health System, West Reading, PA, ⁵Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Increased risk of infections has been recognized in patients with psoriatic arthritis (PsA) compared to those without PsA. Immunomodulatory effects of PsA, immunosuppressive therapies…
Abstract Number: 2826 • 2018 ACR/ARHP Annual Meeting
Emergence of Severe Spondyloarthropathy Related Entheseal Pathology Following Successful Vedolizumab Therapy for Inflammatory Bowel Disease
Sayam Dubash^1,2, Marianayagam Thiraupathy³, Ilaria Tinazzi⁴, Tariq Al Araimi⁵, Christian Pagnoux⁶, Adam Weizman⁷, Pascal Richette^8,9, My-Linh Tran Minh¹⁰, Mattieu Allez¹⁰, Animesh Singh¹¹, Francesco Ciccia¹², John Hamlin¹³, Ai Lyn Tan^1,2, Helena Marzo-Ortega^1,2 and Dennis McGonagle^1,2, ¹Rheumatology, Chapel Allerton Hospital, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ³East and North Hertfordshire NHS Trust, Stevenage, United Kingdom, ⁴Rheumatology, Sacro Cuore-Don Calabria Hospital, Negrar, Italy, ⁵Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, ⁶Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, ⁷Gastroenterology, Mount Sinai Hospital, Toronto, ON, Canada, ⁸Rheumatology, Université Paris Diderot, Paris, France, ⁹Lariboisière Hospital, Lariboisière, University of Paris 7, Paris, France, ¹⁰Department of Gastroenterology, APHP, Hôpital Saint Louis, Sorbonne Paris-Cité University, Paris, France, ¹¹Rheumatology, The Royal Free Hospital, London, United Kingdom, ¹²Rheumatology, University of Palermo, Palermo, Italy, ¹³Department of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Vedolizumab therapy for inflammatory bowel disease (IBD) has been associated with mild spondyloarthritis (SpA) related features including sacroiliitis and synovitis. Herein, we report a…
Abstract Number: 2922 • 2018 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging of Sacroiliac Joints in Patients with Osteitis Condensans Ilii Reveals a Typical Pattern of Lesions Relevant for Differential Diagnosis with Axial Spondyloarthritis
Denis Poddubnyy^1,2, Torsten Diekhoff³, Nino Gobejishvili³, Henning Weineck³, Maria Llop Vilaltella³, Valeria Rios Rodriguez³, Joachim Sieper² and Kay-Geert Hermann³, ¹German Rheumatism Research Centre, Berlin, Germany, ²Charité Universitätsmeidzin Berlin, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Osteitis condensans ilii (OCI) is regarded to as a non-inflammatory disorder induced by mechanical stress and mechanical instability of the sacroiliac joints (SIJ). OCI…
Abstract Number: 577 • 2017 ACR/ARHP Annual Meeting
The Value of C-Reactive Protein As a Predictor of Radiographic Spinal Progression Is Strongly Dependent on β-Fibrinogen and Factor XIII a-Subunit Genotypes in Patients with Axial Spondyloarthritis
Denis Poddubnyy^1,2, Christian Schwedler², Hildrun Haibel², Martin Rudwaleit^2,3, Joachim Sieper² and Berthold Hoppe⁴, ¹German Rheumatism Research Centre, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Berlin, Germany, ³Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany, ⁴Unfallkrankenhaus Berlin, Berlin, Germany
Background/Purpose: It has been shown in the past that inflammatory activity (i.e., elevated C-reactive protein) predicts radiographic spinal progression in patients with axial spondyloarthritis (axSpA).…
Abstract Number: 629 • 2017 ACR/ARHP Annual Meeting
Is Earlier Golimumab Treatment Initiation in Psa and As Patients Associated with Improved Outcomes?
Suneil Kapur¹, Proton Rahman², Michelle Teo³, Jodie Reis⁴, Rajwinder Dhillon⁵, Pauline Boulos⁶, Raman Rai⁷, Regan Arendse⁸, Julie Vaillancourt⁹, Emmanouil Rampakakis⁹, Allen J Lehman¹⁰, Francois Nantel¹¹ and Brendan Osborne¹¹, ¹University of Ottawa, 139 Greenbank Rd, Suite 203, ON, Canada, ²Rheumatology, St Claires Mercy Hospital, St Johns, NF, Canada, ³Balfour Medical Clinic, Penticton, BC, Canada, ⁴University of Saskatchewan, Saskatoon, SK, Canada, ⁵Private Practice, Niagara Falls, ON, Canada, ⁶Private Practice, Dundas, ON, Canada, ⁷Private Practice, Hamilton, ON, Canada, ⁸University of Saskatchewan, Saskatoon, ON, Canada, ⁹JSS Medical Research, Montreal, QC, Canada, ¹⁰Janssen Inc., Toronto, ON, Canada, ¹¹Medical Affairs, Janssen Inc., Toronto, ON, Canada
Background/Purpose: Previous studies have suggested that treating patients earlier with biologics could improve disease outcomes. The aim of this analysis was to assess the impact…
Abstract Number: 1578 • 2017 ACR/ARHP Annual Meeting
The Initiation, but Not the Persistence, of Experimental Spondyloarthritis in HLA-B27/Huβ2m Transgenic Rats Is Crucially Dependent on the IL-23 Axis
Melissa van Tok^1,2, Songqing Na³, Joel Taurog⁴, Dominique Baeten^2,5 and Leonie van Duivenvoorde^1,2, ¹Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Clinical Immunology and Rheumatology/Experimental immunology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³Eli Lilly and Company, Indianapolis, IN, ⁴Dept Int Med-Rheum Dis Div, University of Texas Southwestern Medical Center, Dallas, TX, ⁵Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: IL-17A is a central driver of spondyloarthritis (SpA) pathology. IL-17A production was originally proposed to be IL-23 dependent. Emerging preclinical and clinical evidence from…
Abstract Number: 677 • 2016 ACR/ARHP Annual Meeting
Low Functional Relevance of Radiographic Spinal Progression in Patients with Early Axial Spondyloarthritis
Denis Poddubnyy¹, Hildrun Haibel¹, Jürgen Braun², Martin Rudwaleit³ and Joachim Sieper¹, ¹Charité Medical University, Berlin, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany
Background/Purpose: It has been shown in the past that radiographic spinal progression is an important determinant of the functional outcome in patients with advanced axial…
Abstract Number: 714 • 2016 ACR/ARHP Annual Meeting
Functional Relevance of Structural Damage in the Sacroiliac Joints in Patients with Axial Spondyloarthritis – Results from the German Spondyloarthritis Inception Cohort
Mikhail Protopopov¹, Hildrun Haibel¹, Jürgen Braun², Martin Rudwaleit³, Joachim Sieper¹ and Denis Poddubnyy¹, ¹Charité Medical University, Berlin, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany
Background/Purpose: To analyze the association between the presence of structural damage in the sacroiliac joints and physical function / spinal mobility in patients with axial…
Abstract Number: 2755 • 2016 ACR/ARHP Annual Meeting
Comparison of Clinical Profile of Geriatric and Non-Geriatric Ankylosing Spondylitis (AS) Patients
Ahmed Omar¹, Laura Passalent², Renise Ayearst³, Ismail Sari¹, Anthony V. Perruccio⁴, Rajiv Gandhi⁵, Nigil Haroon¹ and Robert D Inman¹, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ²Allied Health, Toronto Western Hospital, Toronto, ON, Canada, ³Medicine, University Health Network, Toronto, ON, Canada, ⁴Health Care & Outcomes Research, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁵Department of Surgery - Orthopedics, Toronto Western Hospital, Assistant Professor, Department of Surgery, University of Toronto, Toronto, ON, Canada
Background/Purpose: Data on disease characteristics of geriatric patients (>=65 years) with AS are lacking. The objective of this study is to compare: 1) the clinical…
Abstract Number: 683 • 2015 ACR/ARHP Annual Meeting
Referral Strategies for the Early Diagnosis of Axial Spondyloarthritis- a Systematic Review
Abhijeet Danve¹ and Atul A. Deodhar², ¹Internal Medicine - Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²Division of Arthritis & Rheumatic Diseases, Oregon Health & Science University, Portland, OR
Background/Purpose: Axial Spondyloarthritis (axSpA) is often misdiagnosed or diagnosed late (average delay 8 to 11 years) since low back pain (LBP) is very common in…
Abstract Number: 3210 • 2015 ACR/ARHP Annual Meeting
Evaluation of Sacroiliac Joint Radiographs in Patients with Chronic Low Back Pain: Is Erosion the Main Driver of Interreader Disagreement?
Alice Ashouri Christiansen^1,2, Oliver Hendricks^1,2, Dorota Kuettel¹, Kim Hørslev-Petersen^1,2, Anne Grethe Jurik^2,3,4, Steen Nielsen¹, Kaspar Rufibach⁵, Anne Gitte Loft^6,7, Susanne Juhl Pedersen^8,9, Louise Thuesen Hermansen^1,2, Mikkel Østergaard^8,10, Bodil Arnbak^2,4, Claus Manniche^2,4 and Ulrich Weber^1,2, ¹Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, ²Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, ³Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁴Hospital Lillebaelt, Spine Centre of Southern Denmark, Middelfart, Denmark, ⁵rePROstat, Basel, Switzerland, ⁶Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁷Department of Rheumatology, Vejle Hospital, Vejle, Denmark, ⁸Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, ⁹Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark, ¹⁰Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Glostrup, Denmark
Background/Purpose: Evaluation of sacroiliac joints (SIJ) on pelvic radiographs according to the modified New York criteria (mNYc) is considered the gold standard for classification of…
Abstract Number: 632 • 2014 ACR/ARHP Annual Meeting
IL-23 Mediates Psoriasis-like Inflammation in the SKG Mouse Model of Spondyloarthropathy
Helen Benham¹, Linda Rehaume¹, Athan Baillet¹, Zaied Bhuyan¹, Jaclyn Bowman¹, Dimeng Pang¹, Kristine Kikly², Geoffrey Strutton³, Matthew Brown¹ and Ranjeny Thomas¹, ¹University of Queensland Diamantina Institute, Brisbane, Australia, ²Biotechnology Discovery Research, Eli Lilly and Co, Indianapolis, IN, ³Department of Pathology, Princess Alexandra Hospital, Brisbane, Australia
Background/Purpose Psoriasis (Ps) is a common immune-mediated inflammatory skin disease and is a well- recognised extra-articular manifestation of the spondyloathopathies (SpA). Genetic studies implicate IL-23…
Abstract Number: 2697 • 2013 ACR/ARHP Annual Meeting
Identification Of Genetic and Epigenetic Alterations In Spondyloarthritis
Tibor A. Rauch¹, Beata Tryniszewska¹, Andras Vida¹, Timea Ocsko¹, Sandor Szanto², Holly L. Rosenzweig³, Matthew A. Brown⁴, Gethin P Thomas⁵, Katalin Mikecz¹ and Tibor T. Glant¹, ¹Orthopedic Surgery, Rush University Medical Center, Chicago, IL, ²Rheumatology, University of Debrecen, Debrecen, Hungary, ³Oregon Health & Science University, Portland, OR, ⁴Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ⁵Translational Reserch Institute, University of Queensland Diamantina Institute, Woolloongabba, Australia
Background/Purpose: Ankylosing spondylitis (AS) is the prototypic spondyloarthritis and affects approximately 0.2-0.5% of the human population. It is estimated that genetic risk factors contribute >90%…

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