Abstracts tagged "Sjogren’s syndrome"

Abstract Number: 1710 • 2019 ACR/ARP Annual Meeting
Chemokine and Cytokine Tear Profile of Patients with IgG4-Related Disease
Eduardo Martin-Nares¹, Luis Llorente ¹, Guadalupe Lima ¹, Diego Hernández-Ramírez ¹, Isela Chan-Campos ¹, Vanessa Saavedra-González ¹ and Gabriela Hernandez-Molina ¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Background/Purpose: The lacrimal gland is frequently involved in both IgG4-related disease (IgG4-RD) and Sjögren’s syndrome (SS) and presents with swelling and/or dry eye symptoms. Although…
Abstract Number: 2426 • 2019 ACR/ARP Annual Meeting
Distinct Clinical Characteristics of Anti-Ro/SSA Negative Primary Sjögren’s Syndrome: Data from a Cohort for Sjögren’s Syndrome in Korea
Youngjae Park¹, Jennifer Lee ¹, Jung Hee Koh ², Yoon-Kyoung Sung ³, Shin-Seok Lee ⁴, Jung Yoon Choe ⁵, Seung-Cheol Shim ⁶, Ji-Min Kim ⁷, Seong-Ryul Kwon ⁸, Hyun-Ok Kim ⁹, So-Hyang Chung ¹⁰, Wan-Uk Kim ¹, Sung-Hwan Park ¹ and Seung-Ki Kwok ¹, ¹Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, ²Division of Rheumatology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, the Catholic University of Korea, Bucheon, Republic of Korea, ³Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁴Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea, ⁵Division of Rheumatology, Daegu Catholic University Medical Center, Daegu, Republic of Korea, ⁶Division of Rheumatology, Department of Internal Medicine, School of Medicine, Chungnam National University, Chungnam National University Hospital, Daejeon, Republic of Korea, ⁷Division of Rheumatology, Department of Internal Medicine, Keimyung University Dongsan Medical Centre, Daegu, Republic of Korea, ⁸Inha University Hospital, Incheon, Republic of Korea, ⁹Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea, ¹⁰Department of Ophthalmology and Visual Science, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Background/Purpose: To investigate clinical characteristics of patients with primary Sjögren’s syndrome (SS) who were negative for anti-Ro/SSA antibody but positive for minor salivary gland biopsy…
Abstract Number: 1449 • 2019 ACR/ARP Annual Meeting
Clinical Phenotyping of Patients with Primary Sjögren’s Syndrome Using Salivary Gland Ultrasonograhpy
Esther Mossel¹, Jolien van Nimwegen ¹, Robin Wijnsma ¹, Alja Stel ¹, Konstantina Delli ¹, Greetje van Zuiden ¹, Lisette Olie ¹, Leonie Los ¹, Arjan Vissink ¹, Frans Kroese ¹, Suzanne Arends ² and Hendrika Bootsma ³, ¹University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²Dept. of Rheumatology and Clinical Immunology - University Medical Center Groningen (UMCG), University of Groningen, Groningen, Netherlands, ³University of Groningen, Groningen, Netherlands
Background/Purpose: Salivary gland ultrasonography (SGUS) is a promising tool in primary Sjögren’s syndrome (pSS). The objective of this study was to investigate SGUS abnormalities in…
Abstract Number: 1903 • 2019 ACR/ARP Annual Meeting
BTK Overexpression Is Associated with the Risk of Lymphoma in Primary Sjögren’s Syndrome: Data from Whole Blood Transcriptome of 346 Patients Followed-up Prospectively for 10 Years
Pierre-Marie Duret¹, Tao Ye ², Wan-Fai Ng ³, Alain Saraux ⁴, Valérie Devauchelle Pensec ⁵, Raphaele Seror ⁶, Veronique Le-Guern ⁷, Claire Larroche ⁸, Aleth Perdriger ⁹, Jean Sibilia ¹⁰, Jessica Tarn ¹¹, Gaetane Nocturne ¹², Xavier Mariette ¹³ and Jacques-Eric Gottenberg ¹⁴, ¹Hôpitaux civils de Colmar, COLMAR CEDEX, France, ²GenomEAST platform / Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Institut de Génétique et de Biologie Moléculaire, IGBMC, Strasbourg, France, ³Musculoskeletal Research Group Institute of Cellular Medicine Faculty of Medical Sciences Newcastle University, Newcastle, United Kingdom, ⁴CHU de la Cavale-Blanche Brest, Brest, France, ⁵University Hospital of Brest, Brest, France, ⁶Hopitaux universitaires Paris Sud, Kremlin-Bicetre, France, ⁷Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris, France,, Paris, France, ⁸Internal Medicine, Paris, France, Paris, France, ⁹Rheumatology department, Rennes University Hospital, France, Rennes, France, ¹⁰CHU Strasbourg, Strasbourg, France, ¹¹Institute of Cellular Medicine Newcastle University, Newcastle, United Kingdom, ¹²Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France., Paris, France, ¹³Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France, ¹⁴Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France
Background/Purpose: To identify a molecular signature associated with lymphomagenesis in primary Sjögren’s Syndrome (pSS).Methods: Whole peripheral blood samples were collected from 346 well-phenotyped pSS patients…
Abstract Number: 2428 • 2019 ACR/ARP Annual Meeting
Serum Myositis Specific/associate Autoantibodies Help Identify Early Connective Tissue Diseases Relevant Interstitial Lung Diseases: A Medical Center Experience
Chieh-Yu Cheng¹, Wei-Han Ju ¹, Tony Szu-Hsien Lee ², En Chao ¹, Hsiang-Cheng Chen ¹, Feng-Cheng Liu ¹, Deh-Ming Chang ³ and CHUN-CHI LU ⁴, ¹Tri-Service General Hospital, Taipei city, Taiwan (Republic of China), ²National Taiwan Normal University, Taipei city, Taiwan (Republic of China), ³Taipei Veteran General Hospital, Taipei city, Taiwan (Republic of China), ⁴University of Washington, Seattle, WA
Background/Purpose: Interstitial lung diseases (ILD), a heterogeneous group of pulmonary disorders, originated from idiopathic causes or secondary to certain etiologies, such as infectious diseases, drugs,…
Abstract Number: 1450 • 2019 ACR/ARP Annual Meeting
Salivary Gland Hypofunction in a Mouse Model for Sjögren’s Syndrome Is Strongly Associated with Hyperglycemia
Bujana Allushi ¹, Joanna Papinska ¹, Harini Bagavant ¹ and Umesh Deshmukh¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: It has been demonstrated that the non-obese diabetes (NOD) mice from the Jackson Laboratory (JAX) have a distinct gut microbiome and higher incidence of…
Abstract Number: 1905 • 2019 ACR/ARP Annual Meeting
Sicca/Sjögren Syndrome Triggered by PD-1/PD-L1 Checkpoint Inhibitors: Data from the International ImmunoCancer Registry (ICIR)
Manuel Ramos-Casals ¹, Alexandre Maria ², Maria E. Suárez-Almazor ³, Olivier Lambotte ⁴, Benjamin A. Fisher ⁵, Gabriela Hernandez-Molina ⁶, Philippe Guilpain ², Xerxes Pundole ³, Soledad Retamozo⁷, Alejandra Flores-Chávez ⁸, Chiara Baldini ⁹, Clifton Bingham ¹⁰, Pilar Brito-Zerón ¹¹, Jacques-Eric Gottenberg ¹², Marie Kostine ¹³, Timothy R.D. Radstake ¹⁴, Thierry Schaeverbeke ¹⁵, Hendrik Schulze-Koops ¹⁶, Leonard Calabrese ¹⁷, Munther A Khamashta ¹⁸ and Xavier Mariette ¹⁹, ¹Department of Autoimmune Diseases, ICMiD. Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX. Department of Medicine, University of Barcelona, Hospital Clínic, Barcelona, Spain., Barcelona, Spain, ²Department of Internal Medicine, Multi-Organic Diseases, Local Referral Center for Autoimmune Diseases, Saint Eloi Hospital- Montpellier-1 University, Montpellier Cedex 5, France, Montpellier, France, ³Department of Rheumatology/Clinical Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX , USA., Houston, TX, ⁴APHP Médecine Interne/Immunologie Clinique, Hôpital Bicêtre, Paris, France. Université Paris Sud 11 – INSERM U1184 - CEA, Immunology of Viral Infections and Autoimmune Diseases, IDMIT Department, IBFJ, Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Paris, France, ⁵Institute of Inflammation and Ageing, University of Birmingham; and National Institute of Health Research Birmingham Biomedical Research Centre and Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, Birmingham, United Kingdom, ⁶Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ⁷Instituto De Investigaciones En Ciencias De La Salud, Univ. Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Universitario de Ciencias Biomédicas de Córdoba, Córdoba, Argentina., Cordoba, Argentina, ⁸Department of Autoimmune Diseases, ICMiD, Barcelona, Spain., Barcelona, Spain, ⁹Rheumatology Unit, University of Pisa, Italy., Pisa, Italy, ¹⁰Johns Hopkins University, Baltimore, MD, ¹¹Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic. Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona, Spain., Barcelona, Spain, ¹²Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, ¹³Department of Rheumatology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ¹⁴Department of Rheumatology/Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Utrecht, Netherlands, ¹⁵FHU ACRONIM, Department of Rheumatology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ¹⁶Department of Rheumatology/Clinical Immunology, Ludwig-Maximilians-University Munich, Munich, Germany., Munich, Germany, ¹⁷Rheumatologic and Immunologic Disease/Cleveland Clinic, Cleveland, OH, ¹⁸King's College London School of Medicine, London, United Kingdom, ¹⁹Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France
Background/Purpose: To analyse the worldwide occurrence of sicca/Sjögren (SjS) syndrome associated with the use of immune checkpoint inhibitors (ICI) in patients with cancer.Methods: The ImmunoCancer…
Abstract Number: 2430 • 2019 ACR/ARP Annual Meeting
Detection and Clinical Significance of Circulating M3 Muscarinic Acetylcholine Receptor Reactive Th17 Cells in Patients with Primary Sjögren’s Syndrome
Saori Abe¹, Hiroto Tsuboi ¹, Yuko Ono ², Fumika Honda ¹, Mizuki Yagishita ¹, Izumi Kurata ¹, Ayako Ohyama ¹, Hiroyuki Takahashi ¹, Yuya Kondo ¹, Isao Matsumoto ¹ and Takayuki Sumida ¹, ¹Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Science, Faculty of Dental Science, Kyushu University, Tsukuba, Japan
Background/Purpose: Sjögren’s syndrome (SS) is an autoimmune disease which is characterized by lymphocytic infiltration including CD4+ IL-17 producing helper T (Th17) cells to the lacrimal and…
Abstract Number: 541 • 2018 ACR/ARHP Annual Meeting
Prevalence of Sjögren’s Syndrome in Patients with RA Enrolled in a Large Observational US Registry
Leslie R Harrold¹, Ying Shan², Sabrina Rebello², Neil Kramer³, Sean E. Connolly⁴, Evo Alemao⁴, Sheila Kelly⁴, Tammy Curtice⁴, Joel Kremer⁵ and Elliot Rosenstein³, ¹University of Massachusetts, Worcester, MA, ²Corrona, LLC, Southborough, MA, ³Overlook Medical Center, Institute for Rheumatic & Autoimmune Diseases, Summit, NJ, ⁴Bristol-Myers Squibb, Princeton, NJ, ⁵Albany Medical College and the Center for Rheumatology, Albany, NY
Background/Purpose: Sjögren’s syndrome is a known co-existing autoimmune disease in patients with RA, but its prevalence and impact on RA are poorly understood. The aims…
Abstract Number: 1572 • 2018 ACR/ARHP Annual Meeting
Salivary Flow Rates and Oral Health Related Quality of Life Are Associated with Ultrasonographic Scoring of the Major Salivary Glands in Sjogren Syndrome
Yasemin Yalçınkaya¹, Gonca Mumcu², Filiz Ture Ozdemir³, Zeynep Erturk¹, Ali Ugur Unal¹, Pamir Atagunduz⁴, Haner Direskeneli⁵ and Nevsun Inanc^6,7, ¹Department of Internal Medicine, Division of Rheumatology, Marmara University, Istanbul, Turkey, ²Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, ³Marmara University, School of Medicine, Department of Immunology, Istanbul, Turkey, ⁴Department Internal Medicine, Division of Rheumatology, Marmara University,, Istanbul, Turkey, ⁵Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ⁶Marmara University, Istanbul, Turkey, ⁷Departement of İnternal Medicine, Division of Rheumatology, Marmara University, Istanbul, Turkey
Background/Purpose: Ultrasonography (USG) of major salivary glands (SG-USG) as a non-invasive method is widely used to evaluate salivary gland involvement in Sjogren’s syndrome (SjS). Since…
Abstract Number: 2216 • 2018 ACR/ARHP Annual Meeting
Detection of Left Ventricular Regional Function in Primary Sjögren’s Syndrome Patients without Cardiac Symptons, As Assessed By Feature Tracking Cardiac Magnetic Resonance Imaging
Atsuma Nishiwaki¹, Natsumi Ikumi², Hitomi Kobayashi^3,4, Yasuyuki Kobayashi⁵, Isamu Yokoe⁴, Yosuke Nagasawa⁶, Kaita Sugiyama⁶, Takamasa Nozaki⁶, Mitsuhiro Iwata⁴, Noboru Kitamura⁴ and Masami Takei⁴, ¹Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ²Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁵Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ⁶Nihon University School of Medicine, Tokyo, Japan
Background/Purpose: The risk of major cardiovascular (CV) events and the long-term CV outcome in patients with primary Sjögren’s syndrome (pSS) remain unclear. Myocardial disease is…
Abstract Number: 762 • 2018 ACR/ARHP Annual Meeting
Aquaporin-4 Immunoglobulin G Antibody Positive Neuromyelitis Optica Spectrum Disorder and Systemic Autoimmune Diseases Overlap Syndrome: A Single Center Experience
Eduardo Martín Nares¹, Gabriela Hernandez-Molina¹ and Hilda Fragoso-Loyo², ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, México, Mexico
Background/Purpose: The coexistence of neuromyelitis optica spectrum disorder (NMOSD) with other systemic autoimmune diseases is well recognized, especially with systemic lupus erythematosus (SLE) and Sjögren…
Abstract Number: 1574 • 2018 ACR/ARHP Annual Meeting
Autoantibodies Present in Saliva from Sjogren’s Syndrome and Non-Sjogren’s Sicca Patients Are Not Detectible in Serum
Kristi A. Koelsch^1,2,3, Joshua Cavett^3,4, Kenneth Smith³, Jacen Maier-Moore⁵, Astrid Rasmussen³, David M. Lewis⁶, Lida Radfar⁷, Biji T. Kurien^2,4,8, Judith A. James^3,9, Kathy L. Sivils¹⁰, A. Darise Farris¹¹ and R. Hal Scofield^2,11,12, ¹Section of Endocrinology and Diabetes, University of Oklahoma Health Sciences Center, Okalahoma City, OK, ²U.S. Department of Veterans Affairs Medical Center, Oklahoma City, OK, ³Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁵Clinical Laboratory Science, University of Texas at El Paso, El Paso, TX, ⁶Department of Oral and Maxillofacial Pathology, University of Oklahoma College of Dentistry, Oklahoma City, OK, ⁷Department of Oral Diagnosis and Radiology, University of Oklahoma College of Dentistry, Oklahoma City, OK, ⁸Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁹University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹⁰Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma, OK, ¹¹Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹²Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: There is evidence for B cell involvement in the pathogenesis of Sjögren’s syndrome by the presence of autoantigen-specific B cells. Autoantibodies toward Ro/SSA and…
Abstract Number: 2506 • 2018 ACR/ARHP Annual Meeting
The Joint Disease Burden in Patients with Secondary Sjögren’s Syndrome and RA Compared to Patients with RA Only
Evo Alemao¹, Yogesh Saini², Ying Bao¹, Aarti Rao², Christine K Iannaccone³, Michael E Weinblatt³ and Nancy A. Shadick³, ¹Bristol-Myers Squibb, Princeton, NJ, ²Mu Sigma, Bangalore, India, ³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Secondary Sjögren’s syndrome (sSS) is considered a poor prognostic factor in RA and is a common extra-articular manifestation of RA. We estimated prevalence of…
Abstract Number: 1213 • 2018 ACR/ARHP Annual Meeting
Simplified Salivary Gland Ultrasonography for Sjögren Syndrome and Sicca Symptoms: Experience from a Single Medical Center in Taiwan
Yen-Po Tsao¹, Ming-Han Chen², Wei-Sheng Chen³, Chien Chih Lai⁴ and Chang Youh Tsai⁵, ¹Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ²Division of Allergy- Immunology- Rheumatology, Department of Medicine, Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ³Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Department of medicine, division of allergy, immunology, rheumatology, Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ⁵National Yang-Ming University, Taipei, Taiwan
Background/Purpose: Sjögren’s syndrome is an autoimmune disease involving multiple organs, especially the lacrimal and salivary glands. Salivary gland ultrasonography (SGUS) provided a rapid and direct…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].