Date: Monday, October 22, 2018
Session Title: Imaging of Rheumatic Diseases Poster II: Ultrasound
Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Sjögren’s syndrome is an autoimmune disease involving multiple organs, especially the lacrimal and salivary glands. Salivary gland ultrasonography (SGUS) provided a rapid and direct method for evaluation the conditions of salivary glands. Several parameters or evaluation protocols were proposed for stratification the severity of salivary glands. In previous published method, bilateral parotid and submandibular glands were scored from 0 to 4, which resulted in a total score of 0-16. The applications of SGUS was still under investigation and with technique-based barriers.
Total SGUS with 102 patients were retrospectively evaluated. SGUS was conducted by a 10MHz-13MHz linear probe at both parotid and submandibular glands. Each gland was scored from 0 to 4 according to the scoring scale proposed previously. The total maximum score was 16. Simplified SGUS score was conducted through combinations of each two glands from right side and left side.
The average SGUS score of 102 patients was 7.75 (SD 4.769). The correlations between right side and left side was fair (parotid gland, Pearson coefficient 0.889, p<001; submandibular gland, Pearson coefficient 0.843, p<0.001). Compared with parotid gland and submandibular gland in the same side, the correlation was also good (right side, Pearson coefficient 0.640, p<0.001; left side, Pearson coefficient 0.570, p<0.001). The average score of parotid gland and submandibular gland were similar (parotid gland: left side 1.84 (SD 1.426), right side 1.74 (SD 1.528); submandibular gland: left side 2.08 (SD 1.208), right side 2.06 (SD 1.201)). The combination of right side two glands and left side two glands revealed good correlations (p<0.001) with similar score (right side 3.79, left side 3.92). Each side of score correlated well with original score of summation of 4 glands. Both side of SGUS correlated with the severity of small salivary gland biopsy (right side p=0.008, left side p<0.001) and sialocintigraphy (both sides p<0.001).
SGUS could be conducted via only one side of parotid and submandibular gland, which correlated well with the severity of small salivary gland biopsy and sialocintigraphy. This may shorten the examination time and more feasible for practice in clinic. However, SGUS was technique-based and should be trained for certification.
To cite this abstract in AMA style:Tsao YP, Chen MH, Chen WS, Lai CC, Tsai CY. Simplified Salivary Gland Ultrasonography for Sjögren Syndrome and Sicca Symptoms: Experience from a Single Medical Center in Taiwan [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/simplified-salivary-gland-ultrasonography-for-sjogren-syndrome-and-sicca-symptoms-experience-from-a-single-medical-center-in-taiwan/. Accessed March 18, 2019.
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