Abstract Number: 1484 • 2017 ACR/ARHP Annual Meeting
Association between Primary Sjogren’s Syndrome, Arterial Stiffness and Subclinical Atherosclerosis: A Systematic Review and Meta-Analysis
AbstractBackground/Purpose: In rheumatoid arthritis and systemic lupus erythematosus, cardiovascular disease is frequently a major cause of mortality or morbidity. Studies have shown that acute systemic…Abstract Number: 2816 • 2017 ACR/ARHP Annual Meeting
Prediction of Connective Tissue Disease in an at-Risk Cohort Using a Novel Interferon Stimulated Gene Expression Score
Prediction of connective tissue disease in an at-risk cohort using a novel interferon stimulated gene expression scoreBackground/Purpose: A period of ANA positivity and other immune…Abstract Number: 100 • 2017 Pediatric Rheumatology Symposium
Improvement of Salivary Gland Ultrasound Findings in Juvenile Sjögren’s Syndrome after Systemic Corticosteroid Treatment
Background/Purpose: Juvenile Sjögren’sSyndrome (jSS) is a rare systemic autoimmune disease affecting predominantly salivary glands (SG) in children who do not meet criteria for SLE or MCTD. Currently, no specific criteria for…Abstract Number: 656 • 2016 ACR/ARHP Annual Meeting
ERdj5 Function Is Involved in Inflammatory Manifestations of Sjögren’s Syndrome in the Salivary Glands
Background/Purpose: Sjögren’s syndrome is a chronic autoimmune disorder that affects mainly the exocrine glands. The initiation and causative agents are still unknown. Endoplasmic Reticulum (ER)…Abstract Number: 1217 • 2016 ACR/ARHP Annual Meeting
Identification of Sjogren’s Syndrome-Associated Long Non-Coding RNAs That Are Co-Expressed with Key Protein-Coding Transcripts Involved in Dysregulated Interferon Responses
Background/Purpose: The “interferon signature”, marked by transcriptional upregulation of interferon (IFN)-inducible (IFI) genes, is a common finding in Sjögren’s syndrome (SS) that is associated with…Abstract Number: 2682 • 2016 ACR/ARHP Annual Meeting
How Does Primary Sjogren Syndrome Present in Biopsy-Proven Patients without Circulating Ro/La Autoantibodies? Characteristics at Diagnosis of 2073 Patients from the SjöGren Big Data Project
Background/Purpose: To analyse the main characteristics of patients with primary Sjögren syndrome (SjS) with focal lymphocytic sialadenitis (FLS) unrelated to the presence of circulating anti-Ro/La…Abstract Number: 657 • 2016 ACR/ARHP Annual Meeting
Expression of Type-III Interferons (IFNλs) and Their Receptor in Sjögren’s Syndrome
Background/Purpose: Type-III IFNs or IFNλs(IFNλ1/IL29, IFNλ2/IL28A and IFNλ3/IL28B) consist a recently identified group of IFNs,initiallyimplicated inseveral human diseases, including cancer and autoimmunity. In this study,…Abstract Number: 1401 • 2016 ACR/ARHP Annual Meeting
Ultrasonography of Major Salivary Glands in Juvenile SjöGren’s Syndrome − Preliminary Findings in a Multi-Center Study
Background/Purpose: Juvenile Sjögren’s syndrome (jSS) is a rare, poorly defined and possibly underdiagnosed condition. Mean age of diagnosis is approximately 10 years, with major salivary…Abstract Number: 2683 • 2016 ACR/ARHP Annual Meeting
Isolated Anti-La/SS-B Positivity in Patients Diagnosed with Primary Sjogren Syndrome: Analysis of 222 Patients from the Sjogren Big Data Cohort
Background/Purpose: To describe the clinical, immunological and histopathological profile of patients with primary Sjögren syndrome (SjS) presenting with isolated circulating anti-La/SS-B antibodies in the absence…Abstract Number: 659 • 2016 ACR/ARHP Annual Meeting
Low Dose IL-2 Therapy Can Restore the Balance of Th17 and Treg Cells in Refractory Patients with Sjogren’s Syndrome
Background/Purpose: The therapy for sjogren’s syndrome (SS) focuses on biological agents, immune inhibitors and glucocorticoid which can’t correct the problem of unbalance of Th17 and…Abstract Number: 1516 • 2016 ACR/ARHP Annual Meeting
Evidence of Labial Salivary Gland Epithelial Cell Activation from Patients with Rheumatoid Arthritis and Sicca Symptomatology
Background/Purpose: In primary Sjögren’s syndrome (pSS), labial minor salivary gland epithelial cells (LMSGEC) inappropriately express various molecules, including B7, HLA-DR, ICAM, as assessed previously by…Abstract Number: 2685 • 2016 ACR/ARHP Annual Meeting
Ultrasound of the Major Salivary Glands Is a Reliable Imaging Technique for Diagnosing Patients Clinically Suspected with SjöGren’s Syndrome
Background/Purpose: In the classification criteria of Sjögren’s syndrome (SS), involvement of the salivary glands is currently assessed by sialography, scintigraphy, sialometry and histopathology. Recent discussions…Abstract Number: 660 • 2016 ACR/ARHP Annual Meeting
Expression of the Chemokine Receptor CXCR5 Is Decreased in the Periphery of Patients with Primary Sjogren’s Syndrome
Background/Purpose: CXCR5 is a chemokine receptor expressed on B and T cell subsets, which binds the CXCL13 ligand produced by follicular dendritic cells. It is…Abstract Number: 1904 • 2016 ACR/ARHP Annual Meeting
Elevated GITRL Is Associated with Multi-Organ Involvement and Increased Disease Activity of Primarty Sjogren’s Syndrome and Promotes Pathogenic Th1/17 Differentiation
Background/Purpose: Accumulating data showed that Glucocorticoid-induced Tumor Necrosis Factor Receptor Family-related Protein (GITR), with its ligand (GITRL), plays an important role in promoting T-cell-mediated immunity…Abstract Number: 2686 • 2016 ACR/ARHP Annual Meeting
Objective Improvement in Fatigue Scores for Primary Sjögren’s Patients Receiving a Tailored Multidisciplinary Fatigue Intervention in a Generic Fatigue Clinic
Background/Purpose: Primary Sjögren’s syndrome (PSS) is an autoimmune disease which targets secretary glands resulting in dry eyes and mouth. Approximately 70% of PSS patients experience…
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