Abstracts tagged "Sjogren’s syndrome"

Abstract Number: 556 • 2017 ACR/ARHP Annual Meeting
Identification and Validation of S100 Salivary Proteins As Putative Biomarkers for Different Subsets of Primary Sjögren’s Syndrome Patients
Chiara Baldini¹, Francesco Ferro², Nadia Ucciferri³, Enza Polizzi², Silvia Rocchiccioli³, Marta Mosca² and Antonella Cecchettini³, ¹Internal Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, ²Rheumatology Unit, University of Pisa, Pisa, Italy, ³IFC, CNR, Pisa, Italy
Background/Purpose: S100 A proteins are multifunctional proteins expressed predominantly by myeloid cells, with a regulatory role in a variety of cellular processes including inflammation. Recently,…
Abstract Number: 877 • 2017 ACR/ARHP Annual Meeting
Modification of the Classification Criteria for Primary Sjögren Syndrome: An International Vignette Survey
Sandrine Jousse-Joulin¹, Florence Gatineau², Chiara Baldini³, Alan N. Baer⁴, Francesca Barone⁵, Hendrika Bootsma⁶, Simon Bowman⁷, Pilar Brito Zeron⁸, Divi Cornec⁹, Thomas Doerner¹⁰, Salvatore De Vita¹¹, Benjamin Fisher¹², Daniel S. Hammenfors¹³, Malin V. Jonsson¹⁴, Xavier Mariette¹⁵, Vera Milic¹⁶, Hideki Nakamura¹⁷, Wan-Fai Ng¹⁸, Emmanuel Nowak², Manuel Ralos-Casals¹⁹, Astrid Rasmussen²⁰, Raphaèle Seror²¹, Caroline Shiboski²², Takashi Nakamura²³, Arjan Vissink²⁴, Alain Saraux²⁵ and Valérie Devauchelle-Pensec¹, ¹Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ²INSERM CIC 1412, Brest Medical University Hospital, Brest, France, ³Internal Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, ⁴Medicine (Rheumatology), Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham, United Kingdom, ⁶Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands, ⁷Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, Birmingham, United Kingdom, ⁸Autoimmune Diseases Unit, Department of Internal Medicine, Hospital CIMA-Sanitas, Barcelona, Spain, ⁹CHU Brest, Brest, France, ¹⁰Charité Universitätmedizin Berlin and DRFZ, Berlin, Germany, ¹¹Rheumatology Clinic, Academic Hospital S. M. della Misericordia, Medical Area Department, University of Udine, Italy, Udine, Italy, ¹²Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom, ¹³Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, Bergen, Norway, ¹⁴Section for Oral and Maxillofacial Radiology, Department of Clinical Dentistry, University of Bergen, Bergen, Norway, Bergen, Norway, ¹⁵Université Paris Sud, Paris, France, ¹⁶Institute of Rheumatology, School of Medicine, University of Belgrade, Belgrade, Serbia, ¹⁷Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ¹⁸Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ¹⁹Department of Medicine, University of Barcelona, Barcelone, Spain, ²⁰Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²¹Assistance Publique-Hôpitaux de Paris (APHP), Hôpitaux universitaires Paris Sud, Université Paris Sud, kremlin bicetre, France, ²²Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, ²³Department of Radiology and Cancer Biology, Nagasaki University School of Dentistry, Nagasaki, Japan, ²⁴Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ²⁵Rheumatology Department, Rheumatology Department, CHU de la Cavale Blanche, Brest, France, Brest Cedex, France
Background/Purpose: The common classification criteria sets of primary Sjogren syndrome, did not considered the ultrasonography (US) of the major salivary glands as a useful item.…
Abstract Number: 1498 • 2017 ACR/ARHP Annual Meeting
Long-Term Cohort of Patients with a Clinical Diagnosis of Sjogren’s Syndrome: Activity Index and Patient Reported Outcome Performance
Anna Viola Taulaigo¹, Maria Francisca Moraes-Fontes¹, Melissa Fernandes², Vera Bernardino² and Tiago Ramires³, ¹Unidade de Doenças Auto-imunes, Hospital Curry Cabral, Centro Hospitalar de Lisboa Central, Lisbon, Portugal, ²Unidade de Doenças Auto-imunes, Hospital Curry Cabral, Centro Hospitalar de Lisboa Central, Lisboa, Portugal, ³Unidade de Doenças Auto-imunes, Hospital Curry Cabral, Centro Hospitalar de Lisboa Central, Lisbon, Portugal; Serviço de Medicina Interna, Hospital Espírito Santo, Évora, Portugal, Lisbon, Portugal
Background/Purpose: There have been three classification proposals for Sjögren´s Syndrome (SS) over the past 15 years (1-3). The 2016 criteria require a diagnostic work-up which…
Abstract Number: 100 • 2017 Pediatric Rheumatology Symposium
Improvement of Salivary Gland Ultrasound Findings in Juvenile Sjögren’s Syndrome after Systemic Corticosteroid Treatment
Akaluck Thatayatikom¹, Renee F Modica², Daniel S. Hammenfors³, Natalie Jane Shiff¹ and Melissa E Elder², ¹Pediatrics, University of Florida, Gainesville, FL, ²Department of Pediatrics, University of Florida, Gainesville, FL, ³Department of Rheumatology, Haukeland University Hospital, Bergen, Norway
Background/Purpose: Juvenile Sjögren’sSyndrome (jSS) is a rare systemic autoimmune disease affecting predominantly salivary glands (SG) in children who do not meet criteria for SLE or MCTD. Currently, no specific criteria for…
Abstract Number: 667 • 2016 ACR/ARHP Annual Meeting
Cytokine and Chemokine Levels in Serum and Saliva As Disease Activity Biomarkers in Patients with Primary Sjögren’s Syndrome
Angel Tzec-Pérez¹, Rosa Elda Barbosa-Cobos², Gustavo Esteban Lugo-Zamudio³ and Lizbeth Teresa Becerril-Mendoza², ¹Hospital Juárez de México, Mexico city, Mexico, ²Rheumatology, Hospital Juárez de México, Mexico, Mexico, ³Rheumatology, Hospital Juárez de México, México, Mexico
Background/Purpose: Background Evidence suggests that levels of different cytokines in primary Sjögren's syndrome (pSS) are associated with cell infiltration degree within salivary and lacrimal glands…
Abstract Number: 2664 • 2016 ACR/ARHP Annual Meeting
Evaluation of Thyroid Autoimmune Disease in Primary SjöGren’s Syndrome and Its Association with Disease Phenotype
Mario Giron-Pillado¹, Yemil Atisha-Fregoso¹, Ivette Cruz-Bautista¹, Miguel Astudillo-Angel¹ and Gabriela Hernandez-Molina², ¹Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico City, Mexico
Background/Purpose:
Abstract Number: 2875 • 2016 ACR/ARHP Annual Meeting
Depressed Serum IgM Levels in SLE Are Restricted to Defined Subgroups
Caroline Grönwall¹, Uta Hardt¹, Iva Gunnarsson², Gregg J. Silverman³ and Elisabet Svenungsson¹, ¹Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, ²Karolinska Institutet, Department of Medicine, Unit of Rheumatology, Stockholm, Sweden, ³Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Natural IgM autoantibodies have been proposed to have protective properties, and decreased levels of IgM to phosphorylcholine (PC) in SLE are associated with higher…
Abstract Number: 669 • 2016 ACR/ARHP Annual Meeting
RNA-Sequencing Reveals Sjogren’s Syndrome Anti-Ro Negative Patients Share Similar Pathways to Multiple Sclerosis Patients
Indra Adrianto¹, John Ice¹, Astrid Rasmussen², Courtney Montgomery¹, R. Hal Scofield¹, Gabriel Pardo¹, Kathy Sivils¹, Robert Axtell¹ and Christopher Lessard¹, ¹Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, USA, Oklahoma City, OK
Background/Purpose: Sjögren’s syndrome (SS) is an autoimmune disease characterized by autoantibodies to Ro and/or La proteins and lymphocytic infiltration into exocrine glands. Multiple sclerosis (MS)…
Abstract Number: 2668 • 2016 ACR/ARHP Annual Meeting
Real Time Sonoelastography in Primary Sjögren’s Syndrome Correlates with Morphological Ultrasonographic Features and Glandular Activity but Not with Glandular Fibrosis
Gabriela Hernandez-Molina¹, Luis Azpeitia², Sergio Criales-Vera³, Carlos Pacheco⁴, Edgardo Reyes⁵, Guadualupe Lima⁴, Luis Llorente⁶ and Eric Kimura-Hayama³, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico City, Mexico, ²Radiology, Instituto Nacional de Cardiologia, Mexico City, Mexico, ³Radiology Department, Instituto Nacional de Cardiologia, Mexico City, Mexico, ⁴Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁶Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Background/Purpose: Salivary gland ultrasonography is a highly specific tool for the diagnosis of primary Sjögren´s syndrome (PSS). Real time sonoelastography (RTS) is a novel imaging…
Abstract Number: 3029 • 2016 ACR/ARHP Annual Meeting
Ultrasonography of Major Salivary Glands in Patients Suspected with Primary Sjögren’s Syndrome: Comparison with Salivary Gland Biopsy and Classification Criteria
Esther Mossel¹, Konstantina Delli², Jolien F. van Nimwegen³, Alja J. Stel³, Erlin A. Haacke⁴, Fred K.L. Spijkervet⁵, Frans G.M. Kroese³, Arjan Vissink², Hendrika Bootsma⁶ and Suzanne Arends³, ¹University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ²Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ³Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁴Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁵Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁶Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands
Background/Purpose: Ultrasonography of major salivary glands (sUS) is applied in the diagnostic work-up of primary Sjögren's syndrome (pSS). This study aims to assess (i) the…
Abstract Number: 672 • 2016 ACR/ARHP Annual Meeting
Sjogren Big Data Project: Influence of Geolocation on the Phenotypic Expression at Diagnosis in 8310 Patients (North-to-South Gradient)
Pilar Brito-Zerón^1,2, Soledad Retamozo³, Margit Zeher⁴, Astrid Rasmussen⁵, Raphaele Seror⁶, Elke Theander⁷, Xiaomei Li⁸, Chiara Baldini⁹, Jacques-Eric Gottenberg¹⁰, Debashish Danda¹¹, Luca Quartuccio¹², Roberta Priori^13,14, Gabriela Hernandez-Molina¹⁵, Aike A. Kruize¹⁶, Valeria Valim¹⁷, Marika Kvarnström¹⁸, Damien Sene¹⁹, Roberto Gerli²⁰, Sonja Praprotnik²¹, David A. Isenberg²², Roser Solans²³, Maureen Rischmueller²⁴, Seung-Ki Kwok²⁵, Gunnel Nordmark²⁶, Yasunori Suzuki²⁷, Roberto Giacomelli²⁸, Valerie Devauchelle²⁹, Michele Bombardieri³⁰, Benedikt Hofauer³¹, Hendrika Bootsma³², Johan G. Brun³³, Guadalupe Fraile³⁴, Steven E. Carsons³⁵, Tamer Gheita³⁶, Jacques Morel³⁷, Cristina F. Vollenweider³⁸, Fabiola Atzeni³⁹, Nihan Acar-Denizli⁴⁰, Ildike-Fanny Horvath⁴, Kathy Sivils⁵, Thomas Mandl⁴¹, Pulukool Sandhya¹¹, Salvatore De Vita⁴², Jorge Sánchez-Guerrero⁴³, Eefje van der Heijden¹⁶, Virginia Moça Trevisano⁴⁴, Marie Wahren-Herlenius¹⁸, Xavier Mariette⁶, Manuel Ramos-Casals^1,45,46 and EULAR-SS Task Force Big Data Consortium (ASSES, GEAS-SEMI, EULAR), ¹Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Spain, Barcelona, Spain, ²Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona., Bacelona, Spain, ³Rheumatology Unit, Hospital Privado Centro Médico de Córdoba, Argentina, Córdoba, Argentina, ⁴Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Debrecen, Hungary, ⁵Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, USA, Oklahoma City, OK, ⁶Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France, Paris, France, ⁷Department of Rheumatology, Malmö University Hospital, Lund University, Sweden, Malmö, Sweden, ⁸Department of Rheumatology and Immunology, Anhui Medical University Affiliated Provincial Hospital, China, Hefei, Anhui, China, ⁹Rheumatology Unit, University of Pisa, Italy, Pisa, Italy, ¹⁰Department of Rheumatology, Strasbourg University Hospital, Université de Strasbourg, CNRS, Strasbourg, France, Strasbourg, France, ¹¹Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India, Vellore, India, ¹²Rheumatology Clinic, DSMB, University of Udine, Udine, Italy, Udine, Italy, ¹³Rheumatology Unit, Sapienza University of Rome, Rome, Italy, ¹⁴Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, ¹⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico City, Mexico, ¹⁶Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Utrecht, Netherlands, ¹⁷Rheumatology, Department of Medicine, Universidade Federal do Espírito Santo, Vitória, Brazil, Vitória, Brazil, ¹⁸Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, ¹⁹Service de Médecine Interne 2, Hôpital Lariboisière, Université Paris VII, Assistance Publique-Hôpitaux de Paris, 2, Paris, France, Paris, France, ²⁰Clinical and Experimental Medicine, Rheumatology Unit, University of Perugia, Italy, Perugia, Italy, ²¹Department of Rheumatology, University Medical Centre Ljubljana, Slovenia, Ljubljana, Slovenia, ²²Centre for Rheumatology, Division of Medicine, University College London, London, United Kingdom, ²³Autoimmune Systemic Diseases Unit, Department of Internal Medicine, Hospital Vall d'Hebron, Autonomous University of Barcelona, Spain, Barcelona, Spain, ²⁴Department of Rheumatology, School of Medicine, The University of Western Australia, Crawley, Australia, Crawley, Australia, ²⁵Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, South Korea, ²⁶Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Sweden, Uppsala, Sweden, ²⁷Division of Rheumatology, Kanazawa University Graduate School of Medicine, Ishikawa, Japan, Kanazawa, Japan, ²⁸Clinical Unit of Rheumatology, University of l'Aquila, School of Medicine, L'Aquila, Italy, L'Aquila, Italy, ²⁹Service de Rhumatologie, Department of Rheumatology, Brest University Hospital, Brest, France, Brest, France, ³⁰Willian Harvey Research Institute, Centre for Experimental Medicine and Rheumatology, QMUL, UK, London, United Kingdom, ³¹Hals-Nasen-Ohrenklinik und Poliklinik, Technische Universität München, München, Germany, München, Germany, ³²Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands, ³³Department of Clinical Science, University of Bergen. Department of Rheumatology, Haukeland University Hospital, Bergen, Norway, Bergen, Norway, ³⁴Department of Internal Medicine, Hospital Ramón y Cajal, Madrid, Spain, Madrid, Spain, ³⁵Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, NY, USA, Mineola, NY, ³⁶Rheumatology, Rheumatology Department, Faculty of Medicine, Cairo University, Egypt, Cairo, Egypt, ³⁷Department of Rheumatology, Teaching hospital and University of Montpellier, France, Montpellier, France, ³⁸Rheumatology, German Hospital, Buenos Aires, Argentina, Buenos Aires, Argentina, ³⁹IRCCS Galeazzi Orthopedic Institute, Milan, Italy, Milan, Italy, ⁴⁰Department of Statistics, Faculty of Science and Letters, Mimar Sinan Fine Arts University, Turkey, Istabul, Turkey, ⁴¹Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Rheumatology, Malmö, Sweden, Malmö, Sweden, ⁴²Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine, Italy, Udine, Italy, ⁴³Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico, ⁴⁴Federal University of São Paulo, Sao Paulo, Brazil, San Paulo, Brazil, ⁴⁵Sjögren Syndrome Research Group (AGAUR), Barcelona, Spain, ⁴⁶Department of Medicine, University of Barcelona, Barcelona, Spain., Barcelona, Spain
Background/Purpose: To analyse the influence of geolocation (North-to-South gradient) on the clinical presentation of primary Sjögren syndrome (SjS) at diagnosis. Methods: The Big Data Sjögren…
Abstract Number: 2670 • 2016 ACR/ARHP Annual Meeting
Work Disability in Newly Diagnosed Patients with Primary SjöGren’s Syndrome – a Population-Based Cohort Study
Thomas Mandl¹, Tanja Schjødt Jørgensen², Marie Skougaard Nielsen², Peter Olsson¹ and Lars Erik Kristensen³, ¹Dept of Rheumatology, Skane University Hospital Malmö, Lund University, Malmo, Sweden, ²The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ³The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark
Background/Purpose: To study long-term work disability (WD) and possible predictors in newly diagnosed patients with primary Sjögren’s syndrome (pSS). Methods: 51 pSS patients…
Abstract Number: 3031 • 2016 ACR/ARHP Annual Meeting
Rethinking Primary Sjögren’s Syndrome: Stratification By Clinical Phenotypes to Improve Understanding of Disease Pathogenesis, Trial Design, Clinical Management and Prospective Health Gains?
Dennis Lendrem¹, Nadia Howard Tripp^2,3, Xavier Mariette⁴, Svein Joar A. Johnsen⁵, Jessica Tarn⁶, Katie Hackett⁶, Bridget Griffiths⁷, Sheryl Mitchell⁸, Alain Saraux⁹, Valerie Devauchelle¹⁰, Katrine Norheim¹¹, John D. Isaacs¹², Peter McMeekin^13,14, Simon Bowman¹⁵, Roald Omdal¹⁶, Jacques-Eric Gottenberg¹⁷ and Wan-Fai Ng¹⁸, ¹Newcastle upon Tyne, Newcastle University, Newcastle upon Tyne, United Kingdom, ²Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom, ³Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom, ⁴Université Paris-Sud, AP-HP, Hôpitaux Universitaires Paris-Sud, Paris, France, ⁵Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, ⁶Newcastle University, Newcastle-upon-Tyne, United Kingdom, ⁷Rheumatology, Freeman Hospital, Newcastle Upon Tyne, United Kingdom, ⁸Freeman Hospital, Newcastle upon Tyne, United Kingdom, ⁹Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, ¹⁰Service de Rhumatologie, Department of Rheumatology, Brest University Hospital, Brest, France, Brest, France, ¹¹Stavanger University Hospital, Stavanger, Norway, ¹²Newcastle University and the Freeman Hospital, Newcastle-upon-Tyne, United Kingdom, ¹³Institute of Health and Society, Newcastle University, Newcastle-upon-Tyne, United Kingdom, ¹⁴Northumbria University, Newcastle-upon-Tyne, United Kingdom, ¹⁵Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, ¹⁶University of Bergen, Bergen, Norway, ¹⁷Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, ¹⁸Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
Background/Purpose: Primary SjšgrenÕs Syndrome (pSS) is a chronic autoimmune rheumatic disease causing a wide-range of symptoms including dryness, pain and fatigue. Individual patient experiences of…
Abstract Number: 674 • 2016 ACR/ARHP Annual Meeting
Targeting Glandular IL-21-Production in Primary Sjogren′s Syndrome Patients By Immunomodulatory Treatment
Gwenny M. Verstappen¹, Hendrik L.F. Broekman¹, Erlin A. Haacke², Petra M. Meiners³, Fred K.L. Spijkervet³, Arjan Vissink⁴, Hendrika Bootsma⁵ and Frans G.M. Kroese¹, ¹Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ²Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ³Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁵Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands
Background/Purpose: Interleukin-21 plays a central role in plasma cell differentiation and germinal center (GC) formation and is likely involved in the pathogenesis of primary Sjögren’s…
Abstract Number: 2671 • 2016 ACR/ARHP Annual Meeting
Impaired Bone Health in Patients with Primary Sjogren’s Syndrome
Zaiying Hu¹, Shanglin Zhu², Zetao Liao³ and Baiyu Zhang², ¹Department of Rheumatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Rheumatology, 3rd Affiliated Hoapital of Sun Yat-Sen Uni, Guangzhou, China
Background/Purpose: Patients were all Chinese from the outpatient and inpatient clinic of our hospital (Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China). Primary SS…

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