Abstracts tagged "Scleroderma"

Abstract Number: 709 • 2012 ACR/ARHP Annual Meeting
Fingertip Skin Hardness in Limited Scleroderma: Durometry versus Manual Assessment
Thomas Osborn¹, Eric L. Matteson¹, Floranne Ernste², Cynthia S. Crowson³, Deana D. Hoganson⁴ and Irene Z. Whitt⁵, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Division of Rheumatology, Mayo Clinic Rochester, Rochester, MN, ³Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Rheumatology, Mercy Arthritis and Osteoporosis Center, Urbandale, IA, ⁵NIH/NIEHS/Environmental Autoimmunity Group, Bethesda, MD
Background/Purpose: Skin manifestations of scleroderma involve the digits in nearly all patients. Assessment of change at the level of digital skin involvement is difficult. The Modified…
Abstract Number: L14 • 2012 ACR/ARHP Annual Meeting
Treatment of Diffuse Systemic Sclerosis Patients with Anti-Transforming Growth Factor-Beta, Fresolimumab, Inhibits Transforming Growth Factor-Beta-Regulated Gene Expression in Skin and Is Associated with a Rapid Decline in Skin Score
Robert Lafyatis¹, Sashidhar Nakerakanti², Allison Mathes², Cristina Padilla², Sarah McLaughlin³, Michael R. York², Giuseppina Farina⁴, Romy Christmann¹, Richard P. Polisson⁵ and Robert W. Simms¹, ¹Rheumatology, Boston University School of Medicine, Boston, MA, ²Rheumatology, Boston University Medical Center, Boston, MA, ³Division of Rheumatology, Boston University Medical Center, Boston, MA, ⁴Arthritis center, Boston University, Boston, MA, ⁵Sanofi-Aventis US, Cambridge, MA
Background/Purpose: Transforming growth factor-beta (TGFb) has long been suspected to mediate fibrotic signals in systemic sclerosis (SSc) as it potently stimulates collagen deposition in vitro,…
Abstract Number: 2625 • 2012 ACR/ARHP Annual Meeting
The Impact of Sexual Difficulties in Women with Scleroderma and Interpersonal Relationships
Tanaka Ngcozana¹, Louise Parker¹, Christopher P. Denton² and Voon Ong³, ¹Centre for Rheumatology and Connective Diseases, UCL Medical School and Royal Free Hosp, London, United Kingdom, ²Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, London, United Kingdom, ³Department of Rheumatology, UCL Medical School, London, England
Background/Purpose: Sexual problems are common in women with systemic sclerosis (SSc). SSc is a complicated condition linked to a number of complications including sexual dysfunction.…
Abstract Number: 2424 • 2012 ACR/ARHP Annual Meeting
Sleep Disturbances in Systemic Sclerosis: Evidence for the Role of Gastrointestinal Symptoms, Pain, and Pruritus
Katherine Milette¹, Marie Hudson², Annett Koerner¹, Murray Baron³ and Brett D. Thombs⁴, ¹Educational and Counselling Psychology, McGill University, Montreal, QC, Canada, ²Jewish General Hospital, McGill University, Montreal, QC, Canada, ³Pavillion A, Rm 216, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, ⁴Psychiatry, McGill University, Montreal, QC, Canada
Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune connective tissue disorder characterized by thickening and fibrosis of the skin and internal organs. There is significant mortality…
Abstract Number: 1512 • 2012 ACR/ARHP Annual Meeting
Bleomycin Delivery by Osmotic Pump: A Superior Model for Human ILD
Rebecca Lee¹, Michael Bonner², Charles Reese², Elena Tourkina³, Zoltan Hajdu², Jing Zhang², Richard Visconti² and Stanley Hoffman², ¹Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, SC, ³Rheumatology, Medical University of SC, Charleston, SC
Background/Purpose: Interstitial lung disease (ILD) represents a group of chronic, progressive, irreversible diseases associated with pulmonary fibrosis, including systemic sclerosis and idiopathic pulmonary fibrosis. In…
Abstract Number: 1488 • 2012 ACR/ARHP Annual Meeting
Prevalence and Risk Factors of Low Bone Mineral Density in Chinese Patients with Systemic Sclerosis: A Case-Control Study
Chi Chiu Mok, Pak To Chan, Kar Li Chan, Ling Yin Ho and Chi Hung To, Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose: To study the prevalence and risk factors of low bone mineral density (BMD) in patients with systemic sclerosis (SSc). Methods: Consecutive patients who fulfilled…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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