Abstracts tagged "Scleroderma"

Abstract Number: 709 • 2012 ACR/ARHP Annual Meeting
Fingertip Skin Hardness in Limited Scleroderma: Durometry versus Manual Assessment
Thomas Osborn¹, Eric L. Matteson¹, Floranne Ernste², Cynthia S. Crowson³, Deana D. Hoganson⁴ and Irene Z. Whitt⁵, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Division of Rheumatology, Mayo Clinic Rochester, Rochester, MN, ³Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Rheumatology, Mercy Arthritis and Osteoporosis Center, Urbandale, IA, ⁵NIH/NIEHS/Environmental Autoimmunity Group, Bethesda, MD
Background/Purpose: Skin manifestations of scleroderma involve the digits in nearly all patients. Assessment of change at the level of digital skin involvement is difficult. The Modified…
Abstract Number: L14 • 2012 ACR/ARHP Annual Meeting
Treatment of Diffuse Systemic Sclerosis Patients with Anti-Transforming Growth Factor-Beta, Fresolimumab, Inhibits Transforming Growth Factor-Beta-Regulated Gene Expression in Skin and Is Associated with a Rapid Decline in Skin Score
Robert Lafyatis¹, Sashidhar Nakerakanti², Allison Mathes², Cristina Padilla², Sarah McLaughlin³, Michael R. York², Giuseppina Farina⁴, Romy Christmann¹, Richard P. Polisson⁵ and Robert W. Simms¹, ¹Rheumatology, Boston University School of Medicine, Boston, MA, ²Rheumatology, Boston University Medical Center, Boston, MA, ³Division of Rheumatology, Boston University Medical Center, Boston, MA, ⁴Arthritis center, Boston University, Boston, MA, ⁵Sanofi-Aventis US, Cambridge, MA
Background/Purpose: Transforming growth factor-beta (TGFb) has long been suspected to mediate fibrotic signals in systemic sclerosis (SSc) as it potently stimulates collagen deposition in vitro,…
Abstract Number: 2625 • 2012 ACR/ARHP Annual Meeting
The Impact of Sexual Difficulties in Women with Scleroderma and Interpersonal Relationships
Tanaka Ngcozana¹, Louise Parker¹, Christopher P. Denton² and Voon Ong³, ¹Centre for Rheumatology and Connective Diseases, UCL Medical School and Royal Free Hosp, London, United Kingdom, ²Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, London, United Kingdom, ³Department of Rheumatology, UCL Medical School, London, England
Background/Purpose: Sexual problems are common in women with systemic sclerosis (SSc). SSc is a complicated condition linked to a number of complications including sexual dysfunction.…
Abstract Number: 2424 • 2012 ACR/ARHP Annual Meeting
Sleep Disturbances in Systemic Sclerosis: Evidence for the Role of Gastrointestinal Symptoms, Pain, and Pruritus
Katherine Milette¹, Marie Hudson², Annett Koerner¹, Murray Baron³ and Brett D. Thombs⁴, ¹Educational and Counselling Psychology, McGill University, Montreal, QC, Canada, ²Jewish General Hospital, McGill University, Montreal, QC, Canada, ³Pavillion A, Rm 216, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, ⁴Psychiatry, McGill University, Montreal, QC, Canada
Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune connective tissue disorder characterized by thickening and fibrosis of the skin and internal organs. There is significant mortality…
Abstract Number: 1512 • 2012 ACR/ARHP Annual Meeting
Bleomycin Delivery by Osmotic Pump: A Superior Model for Human ILD
Rebecca Lee¹, Michael Bonner², Charles Reese², Elena Tourkina³, Zoltan Hajdu², Jing Zhang², Richard Visconti² and Stanley Hoffman², ¹Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, SC, ³Rheumatology, Medical University of SC, Charleston, SC
Background/Purpose: Interstitial lung disease (ILD) represents a group of chronic, progressive, irreversible diseases associated with pulmonary fibrosis, including systemic sclerosis and idiopathic pulmonary fibrosis. In…
Abstract Number: 1488 • 2012 ACR/ARHP Annual Meeting
Prevalence and Risk Factors of Low Bone Mineral Density in Chinese Patients with Systemic Sclerosis: A Case-Control Study
Chi Chiu Mok, Pak To Chan, Kar Li Chan, Ling Yin Ho and Chi Hung To, Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose: To study the prevalence and risk factors of low bone mineral density (BMD) in patients with systemic sclerosis (SSc). Methods: Consecutive patients who fulfilled…

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