Abstracts tagged "Scleroderma"

Abstract Number: 1386 • ACR Convergence 2020
Clinical Correlates and Relevance of the UCLA GIT 2.0 Instrument for Indication for Esophagogastroduodenoscopy and Endoscopic Esophagitis in Real-life Patients with Systemic Sclerosis
Norina Zampatti¹, Alexandru Garaiman¹, Suzana Jordan¹, Britta Maurer², Rucsandra Dobrota¹, Mike Oliver Becker¹, Oliver Distler³ and Carina Mihai¹, ¹Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, Zurich, ²Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, ³Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, Switzerland
Background/Purpose: Gastrointestinal (GI) tract involvement is the most common of all internal organ involvement in systemic sclerosis (SSc). The University of California at Los Angeles,…
Abstract Number: 2041 • ACR Convergence 2020
Disease Features of Systemic Sclerosis Are Associated with Alterations in Gastrointestinal Microbial Composition in Two Independent Cohorts
Kristofer Andréasson¹, Sungeun Lee², Venu Lagishetty², Meifang Wu², Natalie Howlett², James English², Roger Hesselstrand¹, Jonathan Jacobs² and Elizabeth Volkmann³, ¹Lund University, Lund, Sweden, ²University of California, Los Angeles, Los Angeles, ³University of California, Los Angeles, Los Angeles, CA
Background/Purpose: Previous studies have demonstrated alterations in GI microbiota of patients with systemic sclerosis (SSc) compared with healthy controls [1]. However, these prior studies did…
Abstract Number: 0387 • ACR Convergence 2020
Altered Iron Homeostasis and Pulmonary Haemodynamics in Systemic Sclerosis Associated Pulmonary Arterial Hypertension
Alper Sari¹, Christopher Denton², Svetlana Nihtyanova³, Benjamin Schreiber⁴ and Voon Ong³, ¹Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey, ²University College London, London, United Kingdom, ³Centre for Rheumatology, Royal Free Campus, UCL Division of Medicine, UK, London, United Kingdom, ⁴UCL, London, United Kingdom
Background/Purpose: Iron deficiency (ID) is more frequent in systemic sclerosis (SSc) patients with pulmonary hypertension (PH) than those without and associated with worse prognosis. There…
Abstract Number: 0927 • ACR Convergence 2020
Care Gap in Patients with Systemic Sclerosis with CXR Findings Suggestive of Fibrosis
Sandeep Dhillon¹, Jessica Kapralik², Curtis Sobchak³, Nader Khalidi⁴, Martin Kolb⁵, Nathan Hambly², Gerard Cox², Karen Beattie⁴ and Maggie Larche⁴, ¹McMaster University, Burlington, ON, Canada, ²McMaster University, Hamilton, ³McMaster University, St. Catharines, ON, Canada, ⁴McMaster University, Hamilton, ON, Canada, ⁵McMaster University and Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamliton, ON, Canada
Background/Purpose: Lung involvement, including interstitial lung disease (ILD), is the leading cause of death in patients with systemic sclerosis (SSc). High resolution CT (HRCT) is…
Abstract Number: 1387 • ACR Convergence 2020
Should Systemic Sclerosis Patients with Low Bicarbonate Have Replacement to Prevent Renal Dysfunction?
Megan Meier¹, Jacob Stever², Josephine Wright¹, Tracy Frech³, Greg Stoddard¹ and Benjamin Tingey¹, ¹University of Utah, Salt Lake City, ²University of Utah, SANDY, ³University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake City, UT
Background/Purpose: Scleroderma renal crisis (SRC) is a well-characterized condition in patients with systemic sclerosis, but systemic sclerosis patients frequently develop chronic kidney disease (CKD) without…
Abstract Number: 0390 • ACR Convergence 2020
Baseline Characteristics of Systemic Sclerosis (SSc) Patients with Restrictive Lung Disease in a Multi-Center United States Based Longitudinal Registry
Flavia Castelino¹, John VanBuren², Emily Startup², Shervin Assassi³, Elana Bernstein⁴, Lorinda Chung⁵, Chase Correia⁶, Luke Evnin⁷, Tracy Frech⁸, Jessica Gordon⁹, Faye Hant¹⁰, Laura Hummers¹¹, Dinesh Khanna¹², Nora Sandorfi¹³, Ami Shah¹⁴, Victoria Shanmugam¹⁵ and Virginia Steen¹⁶, ¹Massachusetts General Hospital/Harvard Medical School, Boston, MA, ²University of Utah, Salt Lake City, UT, ³University of Texas Houston McGovern Medical School, Division of Rheumatology and Clinical Immunogenetics, Houston, TX, ⁴Columbia University, New York, NY, ⁵Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA, ⁶Northwestern University, Chicago, IL, ⁷Scleroderma Research Foundation, Brisbane, CA, ⁸University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake City, UT, ⁹Hospital for Special Surgery, New York, NY, ¹⁰Medical University of South Carolina, Charleston, SC, ¹¹Johns Hopkins Univerisity, Ellicott City, MD, ¹²University of Michigan, Ann Arbor, MI, ¹³University of Pennsylvania, Philadelphia, PA, ¹⁴Johns Hopkins University School of Medicine, Ellicott City, MD, ¹⁵The George Washington University, Washington, DC, ¹⁶Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC
Background/Purpose: Interstitial lung disease (ILD) is the leading cause of death in SSc. Several international observational studies have evaluated characteristics of ILD in their SSc patient…
Abstract Number: 0928 • ACR Convergence 2020
Systemic Sclerosis Progression and Pregnancy: A Hopeful Message from the Canadian Scleroderma Registry Database
Siobhan Deshauer¹, Mats Junek², Maggie Larche³ and Karen Beattie³, ¹McMaster University, Hamilton, Canada, ²McMaster University, Hamilton, ³McMaster University, Hamilton, ON, Canada
Background/Purpose: There is limited guidance for women with systemic sclerosis (SSc) in making decisions about pregnancy and informing them about their disease post-partum. Peripartum maternal…
Abstract Number: 1388 • ACR Convergence 2020
A Systematic Assessment of Demographics, Clinical and Serological Features Associated with Colonic Hypomotility in Systemic Sclerosis
Jenice Cheah¹, Jamie Perin², Elizabeth Volkmann³, Laura Hummers⁴, Fredrick Wigley⁵ and Zsuzsanna McMahan⁶, ¹JHUSOM, Baltimore, ²JHUSPH, Baltimore, ³University of California, Los Angeles, Los Angeles, CA, ⁴Johns Hopkins Univerisity, Ellicott City, MD, ⁵Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Johns Hopkins University, Baltimore
Background/Purpose: Colonic dysmotility affects up to 50% of patients with systemic sclerosis (SSc). While some patients have mild colonic disease, others experience severe complications, such…
Abstract Number: 0393 • ACR Convergence 2020
Agreement Between Physician Evaluation and the Composite Response Index in Diffuse Cutaneous Systemic Sclerosis (CRISS)
Boyang Zheng¹, Mianbo Wang², Kerry McKenna³, Lee Shapiro⁴, Robert Spiera⁵, Richard Silver⁶, Mary Ellen Csuka⁷, Frank van den Hoogen⁸, David Robinson⁹, Laura Hummers¹⁰, Thomas Krieg¹¹, Francesco Del Galdo¹², Niall Jones¹³, Nader Khalidi¹⁴, Alessandra Vacca¹⁵, Jessica Gordon¹⁶, John Pauling¹⁷ and Murray Baron¹⁸, ¹McGill University, Montreal, Canada, ²Lady Davis institute for Medical Research, Montreal, QC, Canada, ³Jewish General Hospital, McGill University, Montreal, Canada, ⁴Albany Medical College, Stillwater, NY, ⁵Division of Rheumatology, Hospital for Special Surgery, New York, New York, USA, New York, NY, ⁶Medical University of South Carolina, Charleston, ⁷Medical college of Wisconsin, Milwaukee, WI, ⁸Sint Maartenskliniek, Nijmegen, Netherlands, ⁹University of Manitoba, Winnipeg, MB, Canada, ¹⁰Johns Hopkins Univerisity, Ellicott City, MD, ¹¹University of Cologne, Cologne, Germany, ¹²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom, ¹³Division of Rheumatology, University of Alberta, Edmonton, AB, Canada, ¹⁴McMaster University, Hamilton, ON, Canada, ¹⁵University Hospital of Cagliari, Monserrato, Italy, ¹⁶Hospital for Special Surgery, New York, NY, ¹⁷Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ¹⁸Jewish General Hospital, Montreal, QC, Canada
Background/Purpose: Diffuse cutaneous Systemic Sclerosis (dcSSc) is a morbid disease involving the skin and internal organs. The American College of Rheumatology has provisionally approved a…
Abstract Number: 1055 • ACR Convergence 2020
Myositis and Systemic Sclerosis Spectrum IPAF Patients Are More Likely to Respond Favorably to Immunosuppression
Erin Wilfong¹, Gabriel Schroeder¹, April Barnado¹, Steven Lord¹, Narender Annapureddy¹, Rosemarie Dudenhofer¹ and Leslie J. Crofford¹, ¹Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Classification criteria for interstitial pneumonia with autoimmune features (IPAF) were introduced in 2015 to identify interstitial lung disease (ILD) patients who might benefit from…
Abstract Number: 1393 • ACR Convergence 2020
Systemic Sclerosis: Subclinical Aterosclerosis and Morbimortality
Miriam Retuerto¹, Jose Luis Rosales², Maria Martin¹, Beatriz Joven¹ and Patricia E Carreira¹, ¹Hospital universitario 12 de octubre, Madrid, Spain, ²Hospiten Rambla, Santa Cruz de Tenerife, Spain
Background/Purpose: Rheumatic diseases are associated with accelerated atherosclerosis, and an increase in cardiovascular morbidity and mortality. This process is mediated by classic cardiovascular risk factors…
Abstract Number: 0394 • ACR Convergence 2020
Prevalence of a Diagnosis of Osteopenia/Osteoporosis Amongst Patients with Systemic Sclerosis and Identification of Associated Clinical Factors
Guanying Wang¹, Diane Mar², Joy Wu³, Julia Simard⁴, Rita Popat¹ and Lorinda Chung⁵, ¹Department of Epidemiology & Population Health, Stanford University School of Medicine, Palo Alto, CA, ²Stanford Department of Immunology/Rheumatology, Palo Alto, CA, ³Department of Medicine, Division of Endocrinology, Stanford University School of Medicine, Palo Alto, CA, ⁴Stanford Medicine, Stanford, CA, ⁵Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA
Background/Purpose: This study aims to determine the prevalence of a diagnosis of osteopenia/osteoporosis (OP) in systemic sclerosis (SSc) patients and to identify the clinical and…
Abstract Number: 1064 • ACR Convergence 2020
Anti-SMN Autoantibodies Are Associated with Systemic Sclerosis Small Bowel Involvement in anti-U1RNP Positive Autoimmune Myositis
Caroline Vo¹, Océane Landon-Cardinal², Alexandra Albert³, Alain Meyer⁴, Valérie Leclair⁵, Josiane Bourré-Tessier², Sabrina Hoa², Eric Rich¹, Jean-Richard Goulet¹, Benjamin Ellezam⁶, Maude Bouchard-Marmen⁷, Martial Koenig⁸, Geneviève Gyger⁵, Ira N. Targoff⁹, Marie Hudson⁵, Minoru Satoh¹⁰, Marvin Fritzler¹¹, Yves Troyanov¹² and Jean-Luc Senécal², ¹Division of Rheumatology, Centre hospitalier de l'Université de Montréal, Department of Medicine, Université de Montréal, Montréal, QC, Canada, ²Division of Rheumatology, Centre hospitalier de l'Université de Montréal, Montréal, QC, Canada, ³Division of Rheumatology, Centre Hospitalier de l’Université Laval, Québec, QC, Canada, ⁴Service de rhumatologie et Centre de références des maladies autoimmunes rares, Hôpitaux universitaires de Strasbourg, Strasbourg, Alsace, France, ⁵Division of Rheumatology, Jewish General Hospital, Montréal, QC, Canada, ⁶Division of Pathology, Centre hospitalier universitaire Sainte-Justine, Montréal, QC, Canada, ⁷Division of Rheumatology, Centre Hospitalier de l’Université Laval, Department of Medicine, Université Laval, Québec, QC, Canada, ⁸Division of Internal Medicine, Centre hospitalier de l'Université de Montréal, Department of Medicine, Université de Montréal, Montréal, QC, Canada, ⁹University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹⁰Department of Clinical Nursing, University of Occupational and Environmental Health, Kitakyushu, Japan, ¹¹Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ¹²Division of Rheumatology, Hôpital du Sacré-Coeur, Montréal, QC, Canada
Background/Purpose: The survival of motor neuron (SMN)/gemin proteins are components of a multifunctional protein complex that plays an essential role in RNA metabolism. SMN is…
Abstract Number: 1398 • ACR Convergence 2020
The Isolated Nucleolar Pattern ANA Antibody in a Systemic Sclerosis Patient Cohort
Sabrina Elliott¹, Duncan Moore² and Virginia Steen², ¹MedStar Georgetown Hospital, Alexandria, VA, ²Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC
Background/Purpose: Systemic Sclerosis (SSc) patients with an isolated nucleolar patterned ANA (NUC ANA) make up about 15% of the SSc population, although the specific nucleolar…
Abstract Number: 0397 • ACR Convergence 2020
Assessing Adherence to Screening of Systemic Sclerosis-Related Lung Disease
Matthew Herrmann¹ and Zineb Aouhab¹, ¹Loyola University Medical Center, Maywood, IL
Background/Purpose: Feared complications of systemic sclerosis (SSc) affect the pulmonary system, with pulmonary hypertension and interstitial lung disease being common causes of mortality. Baseline and…

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