ACR Meeting Abstracts

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Abstracts tagged "Scleroderma, Localized"

  • Abstract Number: 0332 • ACR Convergence 2023

    Initial Characterization of a Skin Symptom Questionnaire for Patients with Systemic Sclerosis

    Jeong Min Yu1, John VanBuren2, Angela Child2, Jessica Alvey2, Lisa Mandl3, Laura Pinheiro4, Shervin Assassi5, Elana Bernstein6, Flavia Castelino7, Lorinda Chung8, Luke Evnin9, Tracy Frech10, Faye Hant11, Laura Hummers12, Dinesh Khanna13, Kimberly Lakin1, Dorota Lebiedz-Odrobina14, Yiming Luo15, Ashima Makol16, Jerry Molitor17, Duncan Moore18, Carrie Richardson19, Nora Sandorfi20, Ami Shah21, Ankoor Shah22, Victoria Shanmugam23, Brian Skaug24, Virginia Steen25, Elizabeth Volkmann26 and Jessica Gordon1, 1Hospital for Special Surgery, New York, NY, 2University of Utah, Salt Lake City, UT, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 4Weill Cornell Medicine College, New York, NY, 5University of Texas McGovern Medical School at Houston, Houston, TX, 6Columbia University, New York, NY, 7Massachusetts General Hospital, Boston, MA, 8Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Woodside, CA, 9Scleroderma Research Foundation, Brisbane, CA, 10Vanderbilt University Medical Center, Nashville, TN, 11Medical University of South Carolina, Charleston, SC, 12Johns Hopkins University, Baltimore, MD, 13University of Michigan, Ann Arbor, MI, 14University of Utah, Cottonwood Heights, UT, 15Division of Rheumatology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, 16Mayo Clinic, Rochester, MN, Rochester, MN, 17University of Minnesota, Minneapolis, MN, 18Northwestern Memorial Hospital, Chicago, IL, 19Northwestern University, Riverside, IL, 20University of Pennsylvania, Philadelphia, PA, 21Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Ellicott City, MD, 22Duke University, Durham, NC, 23Victoria Shanmugam, MD, Great Falls, VA, 24Division of Rheumatology, University of Texas McGovern Medical School, Houston, TX, 25Georgetown University School of Medicine, Washington, DC, 26University of California Los Angeles, Los Angeles, CA

    Background/Purpose: Skin disease is a hallmark of systemic sclerosis (SSc). The modified Rodnan skin score (mRSS) is physician performed measurement that assesses the extent and…
  • Abstract Number: 0639 • ACR Convergence 2023

    Evaluating Esophageal Dysmotility by Scintigraphy in Systemic Sclerosis: Subsets and Phenotypes

    Antonio Salas1, Lisa Yanek2 and Zsuzsanna McMahan3, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University School of Medicine Department of Medicine, Baltimore, MD, 3Johns Hopkins Rheumatology, Lutherville, MD

    Background/Purpose: Gastrointestinal (GI) dysmotility affects most patients with systemic sclerosis (SSc), and the esophagus is the most commonly affected region. While most SSc patients are…
  • Abstract Number: 054 • 2023 Pediatric Rheumatology Symposium

    Craniofacial Localized Scleroderma: A Single Center Retrospective Cohort

    Leigh Stubbs, Ammar Hashemi, Raegan Hunt and Renata Maricevich, Baylor College of Medicine, Houston, TX

    Background/Purpose: Craniofacial localized scleroderma (LS) can lead to disfigurement and severe extracutaneous manifestations (ECMs). There is an ongoing need to standardize multidisciplinary evaluation and care.…
  • Abstract Number: 106 • 2023 Pediatric Rheumatology Symposium

    Caregivers’ Perspectives on Barriers to Care in Juvenile Localized and Systemic Scleroderma

    Leigh Stubbs1, Andrew Ferry2, Danielle Guffey1, Christina Loccke3, Erin Moriarty Wade3, Pamela Pour3, Kaveh Ardalan4, Peter Chiraseveenuprapund5, Ingrid Ganske6, Daniel Glaser7, Gloria Higgins8, Nadia Luca9, Katharine Moore10, Vidya Sivaraman11, Katie Stewart1, Natalia Vasquez Canizares12, Raegan Hunt1, Renata Maricevich1, Kathryn Torok13 and Suzanne Li14, 1Baylor College of Medicine, Houston, TX, 2Oregon Health and Science University, Portland, OR, 3n/a, 4Duke University School of Medicine, Durham, NC, 5University of California - San Diego, San Diego, CA, 6Boston Children’s Hospital and Harvard Medical School, Boston, MA, 7Yale University School of Medicine, New Haven, CT, 8Nationwide Childrens Hospital/ The Ohio State University, Columbus, OH, 9University of Calgary, Calgary, AB, Canada, 10University of Colorado / Children's Hospital Colorado, Denver, CO, 11Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 12Children's Hospital at Montefiore, New York, NY, 13University of Pittsburgh, Pittsburgh, PA, 14Hackensack Meridian School of Medicine, Joseph M. Sanzari Children's Hospital, Hackensack, NJ

    Background/Purpose: Juvenile localized scleroderma (LS) and systemic sclerosis (SSc) are rare rheumatic diseases often associated with severe morbidities. Delays in diagnosis are common, putting children…
  • Abstract Number: 1946 • ACR Convergence 2022

    Focused Clinical Correlation of Autoantibody Testing in Juvenile Systemic Sclerosis and Localized Scleroderma Using the Euroimmun™ Scleroderma Disease Profile

    Jonathan Li1, Emily Mirizio2, Katherine Buhler3, Anne Stevens4, May Choi5, Kaila Schollaert-Fitch2, Kathryn Torok2, Christopher Liu2 and Marvin Fritzler3, 1Combined Internal Medicine-Pediatrics Residency Program, Children's Hospital of UPMC, Pittsburgh, PA, 2Pediatric Rheumatology, Children's Hospital of UPMC, Pittsburgh, PA, 3University of Calgary, Calgary, AB, Canada, 4Janssen, Hansville, WA, 5Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada

    Background/Purpose: Commercially available autoantibody (AAb) panels are developed for adult rheumatological diseases; application to pediatric disease has not been established. As a pediatric scleroderma referral…
  • Abstract Number: 1366 • ACR Convergence 2022

    Developing a Mobile App to Facilitate Disease Activity Assessment in Localized Scleroderma

    Suzanne Li1, Xiaohu Li2, Tara Lozy3 and Jiajun Chen4, 1Hackensack Meridian School of Medicine, Joseph M. Sanzari Children's Hospital, West Orange, NJ, 2Stevens Institute of Technology, Hoboken, NJ, 3Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, 4One Node Lab, League City, TX

    Background/Purpose: Juvenile localized scleroderma (jLS) is an inflammatory and fibrosing disease that causes severe morbidity (e.g., hemiatrophy, arthropathy, seizures), with functional impairment found in >25%…
  • Abstract Number: 1368 • ACR Convergence 2022

    How Common Is the Coexistence of Juvenile Localized and Systemic Scleroderma? Results of a Multination Survey

    Ivan Foeldvari1, Nicola Helmus2 and Suzanne Li3, 1Hamburger Zentrum für Kinder- und Jugendrheumatologie, Hamburg, Germany, 2Hamburg Centre for Pediatric and Adolescence Rheumatology, Hamburg, Germany, 3Hackensack Meridian School of Medicine, Joseph M. Sanzari Children's Hospital, West Orange, NJ

    Background/Purpose: Pediatric scleroderma consists of two diseases, juvenile localized scleroderma (jLS) and juvenile systemic sclerosis (jSSc). While jLS and jSSc share some disease processes, there…
  • Abstract Number: 1382 • ACR Convergence 2022

    Juvenile Eosinophilic Fasciitis: A Single-Center Cohort

    Leigh Stubbs1, Oluwaseun Ogunbona2, Adekunle Adesina1, Sara Anvari1, Emily Beil1, Jamie Lai1, Andrea Ramirez1, Vibha Szafron1, Matthew Ditzler1 and Marietta DeGuzman1, 1Baylor College of Medicine, Houston, TX, 2Houston Methodist Hospital, Houston, TX

    Background/Purpose: Eosinophilic fasciitis (EF) is a rare fibrosing disease. Since described in 1975, less than 30 pediatric cases have been reported. EF presents with painful…
  • Abstract Number: 1518 • ACR Convergence 2022

    Prevalence, Risk Factors and Treatment Patterns of Digital Ischemic Complications in Systemic Sclerosis: A Single Center Cross-Sectional Study

    Ashima Makol1, Alicia Hinze2, Rachel Giblon1, Yasser Radwan3, Tina Gunderson4, David Liedl1, Kenneth J. Warrington4, Cynthia Crowson5 and Paul Wennberg1, 1Mayo Clinic, Rochester, MN, Rochester, MN, 2Mayo Clinic - Rochester, MN, Rochester, MN, 3Mayo Clinic/ Michigan State University, Lansing, MI, 4Mayo Clinic, Rochester, MN, 5Mayo Clinic, Eyota, MN

    Background/Purpose: Digital ischemic complications (DICs, including digital ulcers, digital pitting/scars, gangrene and/or amputation) can significantly impact hand function, disability and overall prognosis in SSc. We…
  • Abstract Number: 1542 • ACR Convergence 2022

    Exploratory Clinical Subgroup Clustering in Systemic Sclerosis – Results from the Indian Progressive Systemic Sclerosis Registry

    Shery Susan Philip1, Ramya Janardana1, Revanesh S Mirji1, Chengappa Kavadichanda2, Devender Bairwa3, Geetabali Sircar4, Parasar Ghosh5, Anupam Wakhlu6, Padmanabha Shenoy7, Sumithra Selvam8 and Vineeta Shobha1, 1St. John’s Medical College Hospital, Bangalore, India, 2JIPMER, Pondicherry, Puducherry, India, 3Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, Puducherry, India, 4Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India, 5Govt of West Bengal, Kolkata, India, Kolkata, West Bengal, India, 6Apollo Medics Super Speciality Hospitals, Lucknow, India, 7Centre for Arthritis and Rheumatism Excellence (CARE), Cochi, India, 8Division of Epidemiology and Biostatistics, St. John’s Research Institute, St. John's Medical College Hospital, Bangalore, India

    Background/Purpose: Classification of systemic sclerosis (SSc) into subsets has been a challenge due to it's heterogeneity. This study attempts to identify SSc subsets based on…
  • Abstract Number: 0772 • ACR Convergence 2021

    Pediatric Craniofacial Scleroderma: Assessing Handheld 3D Stereophotogrammetric Imaging Feasibility and Reliability

    Daniel Glaser1, Kaila Schollaert-Fitch2, Christopher Liu1, Jesse Goldstein1 and Kathryn Torok2, 1UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Craniofacial scleroderma (Cf-LS), also known as Parry-Romberg Syndrome or scleroderma en coup de sabre, is a subtype of localized scleroderma (morphea). Diagnosis and monitoring…
  • Abstract Number: 0781 • ACR Convergence 2021

    Long-Term Follow-up of Juvenile Localized Scleroderma Patients Treated with Methotrexate-Based Standardized Regimens (Consensus Treatment Plans)

    Suzanne Li1, Aaron Thammavongxay2, Maria Ibarra3, Kathryn Torok4, Polly Ferguson5, C Egla Rabinovich6, Robert Fuhlbrigge7, Katie Stewart8, Elena Pope9, Ronald Laxer10, Sandy Hong11, Thomas Mason12, Mara Becker13, Gloria Higgins14, Fatma Dedeoglu15 and for the CARRA Legacy Registry16, 1Hackensack Meridian School of Medicine, Joseph M. Sanzari Children's Hospital, West Orange, NJ, 2Bergen Academies, Hackensack, NJ, 3Children's Mercy Hospital, Kansas City, MO, 4University of Pittsburgh, Pittsburgh, PA, 5University of Iowa Carver College of Medicine, Iowa City, IA, 6Duke Childrens Hospital & Health Center, Durham, NC, 7University of Colorado, Denver, CO, 8UT Southwestern, Dallas, TX, 9Hospital for Sick Kids, Toronto, ON, Canada, 10SickKids, Toronto, ON, Canada, 11University of Iowa Stead Family Children's Hospital, Iowa City, IA, 12Mayo Clinic, Rochester, MN, 13Duke University Medical Center/Duke Clinical Research Institute, Chapel Hill, NC, 14Ohio State University, Columbus, OH, 15Boston Children's Hospital, Boston, MA, 16Childhood Arthritis and Rheumatology Research Alliance, Milwaukee, WI

    Background/Purpose: Juvenile localized scleroderma (jLS) is a rare chronic inflammatory and fibrosing disease associated with a high risk for morbidity in children. Methotrexate (MTX) has…
  • Abstract Number: 0979 • ACR Convergence 2021

    Autoantibody Testing in Juvenile Localized Scleroderma and Systemic Sclerosis: Comparing Antibody Profiles and Clinical Correlations

    Jonathan Li1, Emily Mirizio1, Katherine Buhler2, May Choi3, Haiyan Hou2, Giffin Werner1, Anwesha Sanyal1, Kaila Schollaert-Fitch1, Marvin Fritzler2 and Kathryn Torok1, 1University of Pittsburgh, Pittsburgh, PA, 2University of Calgary, Calgary, AB, Canada, 3Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada

    Background/Purpose: Pediatric scleroderma encompasses juvenile onset localized scleroderma (jLS) and juvenile onset systemic sclerosis (jSSc), both of which present with varied cutaneous fibrosis and systemic…
  • Abstract Number: 1856 • ACR Convergence 2021

    Serum IFN Score Predicts Long Term Outcome in Limited Cutaneous SSc

    Ranjitha Karanth1, Giuseppina Abignano2, Vishal Kakkar2, Rebecca Ross2, Christopher Denton3 and Francesco Del Galdo2, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, LTHT, Leeds, United Kingdom, 2University of Leeds, Leeds, United Kingdom, 3University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, United Kingdom

    Background/Purpose: Limited cutaneous systemic sclerosis (lcSSc) carries a highly variable prognosis and to date there are no stratification tools to predict clinical outcomes. Evidence suggests…
  • Abstract Number: 0175 • ACR Convergence 2020

    Identifying Immuno-phenotypes in Juvenile Localized Scleroderma with RNA Sequencing

    Christina Schutt1, Emily Mirizio2, Kaila Schollaert-Fitch2, Claudia Salgado3, Miguel Reyes-Mugica3 and Kathryn Torok2, 1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Pittsburgh Medical Center, Pittsburgh

    Background/Purpose: Juvenile localized scleroderma (jLS) is an autoimmune disease of the skin and underlying tissue characterized by an early inflammatory infiltrate followed by fibrosis and…
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