ACR Meeting Abstracts

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Abstracts tagged "scleroderma and systemic sclerosis"

  • Abstract Number: 2716 • 2014 ACR/ARHP Annual Meeting

    Development of a “Renal Crisis Prevention Card” As an Educational Tool Aimed at Improving Outcomes in High-Risk Patients with Systemic Sclerosis

    Lee S. Shapiro1,2,3, Lesley Ann Saketkoo4, Jessica F. Farrell2,3,5 and Kim Fligelstone6, 1Albany Medical College, Albany, NY, 2Steffens Scleroderma Center, Saratoga Springs, NY, 3The Center for Rheumatology, Albany, NY, 4Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, 5Pharmacy Practice, Albany College of Pharmacy & Health Sciences, Albany, NY, 6Royal Free Hospital, Scleroderma Unit and Scleroderma Society, London, United Kingdom

    Background/Purpose:   Scleroderma renal crisis (SRC) is a devastating complication of SSc.   The introduction of effective treatment with ACE inhibition (ACE-I) in 1979 dramatically reduced…
  • Abstract Number: 2699 • 2014 ACR/ARHP Annual Meeting

    Optimizing Scleroderma Centers of Excellence: Perspectives from Patients and Scleroderma (SSc) Experts

    Veronika K. Jaeger1, Andrew Aubin2, Nancy Baldwin3, Kim Fligelstone4, Robyn Sims5, Joep Welling6, Ryan Burrill7, Kerri Connolly7, Tracy Frech8, Jessica K. Gordon9, Tanaka Ngcozana10, Monika Kowalczyk11, Matthew R. Lammi12, Ulrich A. Walker1 and Lesley Ann Saketkoo13, 1Department of Rheumatology, University Hospital Basel, Basel, Switzerland, Basel, Switzerland, 2Louisiana State University School of Medicine, New Orleans, LA, 3Scleroderma Foundation - Chicago Support Group, Chicago, IL, 4Royal Free Hospital, Scleroderma Unit and Scleroderma Society, London, United Kingdom, 5Scleroderma Australia, Victoria, Australia, 6The Dutch Patient Organization for Systemic Autoimmune Diseases, Utrecht, Netherlands, 7Scleroderma Foundation, Boston, MA, 8Div of Rheumatology, University of Utah, Salt Lake City, UT, 9Rheumatology, Hospital for Special Surgery, New York, NY, 10Rheumatology Department, Lower, Royal Free hospital, London, United Kingdom, 11DIvision of Gastroenterology, Tulane University School of Medicine, New Orleans, LA, 12Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, 13Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA

    Background/Purpose:   SSc is a complex, diffuse, devastating health condition of vascular injury, inflammation and fibrosis resulting in multiple organ-system derangements with high impact on…
  • Abstract Number: 1931 • 2014 ACR/ARHP Annual Meeting

    Mycophenolate Mofetil (MMF) Use in Scleroderma Patients with Pulmonary  Hypertension: Observations from the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Cohort

    Lesley Ann Saketkoo1, Matthew R. Lammi2, Aryeh Fischer3, Jerry A. Molitor4 and Virginia D. Steen5, 1Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, 2Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, 3Rheumatology / ILD Program, National Jewish Health, Denver, CO, 4Rheumatology, University of Minnesota, Minneapolis, MN, 5Department of Rheumatology, Georgetown University Medical Center, Washington, DC

    Background/Purpose: Systemic sclerosis (SSc) related pulmonary hypertension (PH) carries a high mortality and patients with SSc-PH related to restrictive lung disease having an even worse…
  • Abstract Number: 1930 • 2014 ACR/ARHP Annual Meeting

    The Value of Repeated Nailfold Capillaroscopy in Raynaud’s Phenomenon in Daily Practice: A Follow-up Study in the Netherlands

    B. de Boer1, J. Meijs1, J. van Aken2, T.W.J. Huizinga1, A.a. Schouffoer3 and J.K. de Vries-Bouwstra4, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Spaarne Ziekenhuis, Hoofddorp, Netherlands, 3Rheumatology, Haga Hospital, The Hague, Netherlands, 4Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose Nailfold capillaroscopy is an important tool to differentiate primary Raynaud's phenomenon (PRP) from secondary Raynaud's phenomenon (SRP). Based on possible transition from PRP to…
  • Abstract Number: 1684 • 2014 ACR/ARHP Annual Meeting

    Treatment of Scleroderma Associated Lung Disease with Mycophenolate Mofetil: A Community-Based Study

    Audrey Bearden1, Kent Kwasind Huston2 and Judy Foxworth3, 1Internal Medicine, University of Missouri-Kansas City, Kansas City, MO, 2Rheumatology, The Center for Rheumatic Disease, Kansas City, MO, 3Associate Program Director & Director of Research, The University of Missouri-Kansas City, Kansas City, MO

    Background/Purpose:  Interstitial lung disease occurs in over 80% of patients with scleroderma. Cyclophosphamide is the only treatment proven to benefit scleroderma lung disease in a…
  • Abstract Number: 1694 • 2014 ACR/ARHP Annual Meeting

    a Feasibility Study of Subjective and Objective Assessment of Sublingual Abnormalities in Systemic Sclerosis

    Tracy M. Frech1, John Pauling2, Maureen Murtaugh3, Lee S. Shapiro4, Bernard Choi5, Ryan Farraro5 and Robyn T. Domsic6, 1Internal Medicine, Salt Lake City VAMC, Salt Lake, UT, 2Upper Borough Walls, Royal National Hospital for Rheumatic Disease, Bath, United Kingdom, 3Internal Medicine-Division of Epidemiology, University of Utah School of Medicine, SLC, UT, 4The Center for Rheumatology, Albany, NY, 5University of Irvine, Irvine, CA, 6Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Sublingual frenulum abnormalities are reported in systemic sclerosis (SSc), but the exact nature and clinical relevance of such abnormalities is unknown.  Laser speckle contrast…
  • Abstract Number: 1691 • 2014 ACR/ARHP Annual Meeting

    Systemic Sclerosis Patients with Pulmonary Hypertension Have a Lower Change in End Tidal Carbon Dioxide Following Three Minutes of Step Exercise Than Systemic Sclerosis Patients without Pulmonary Hypertension: A Cross-Sectional Study

    Elana J. Bernstein1, Jessica K. Gordon2, Robert F. Spiera2, Wei-Ti Huang3, Evelyn M. Horn4 and Lisa A. Mandl2, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Biostatistics, Hospital for Special Surgery, New York, NY, 4Cardiology, New York Presbyterian Hospital/Weill Cornell Medical College, New York, NY

    Background/Purpose: Pulmonary hypertension (PH) is a leading cause of death in patients with systemic sclerosis (SSc).  Transthoracic echocardiogram and pulmonary function testing are standard noninvasive…
  • Abstract Number: 1682 • 2014 ACR/ARHP Annual Meeting

    Mycophenolate Mofetil Versus Azathioprine in Scleroderma-Associated Interstitial Lung Disease: Results from the Australian Scleroderma Cohort Study

    Claire Owen1, Gene Ngian2, Kathleen Elford2, Owen Moore3, Mandy Nikpour3, Wendy Stevens3, Susanna Proudman4, Janet Roddy5, Jane Zochling6, Catherine Hill7, Peter Nash8, Allan Sturgess9 and Joanne Sahhar2, 1Rheumatology, Monash Health, Melbourne, Australia, 2Monash Health, Melbourne, Australia, 3St Vincent's Hospital, Melbourne, Australia, 4Royal Adelaide Hospital, Adelaide, Australia, 5Royal Perth Hospital, Perth, Australia, 6Department of Rheumatology, Menzies Research Institute Tasmania, Hobart, TAS, Australia, 7Queen Elizabeth Hospital, Adelaide, Australia, 8Sunshine Coast Rheumatology, Maroochydore, Australia, 9The St George Hospital, Sydney, Australia

    Background/Purpose: Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is common and when progressive, associated with significant morbidity and mortality. Cyclophosphamide is frequently used as first line…
  • Abstract Number: 1745 • 2013 ACR/ARHP Annual Meeting

    Prediction Of Pulmonary Complications In Systemic Sclerosis – Model Development and Validation

    Svetlana I. Nihtyanova1, Benjamin E. Schreiber2, Voon H. Ong3, John G. Coghlan4, Athol U. Wells5 and Christopher P. Denton6, 1Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, 2Royal Free Hospital NHS Foundation Trust, National Pulmonary Hypertension Service, London, United Kingdom, 3Department of Rheumatology, The Royal Free and University College Medical School, London, United Kingdom, 4National Pulmonary Hypertension Service, The Royal Free Hospital NHS Foundation Trust, London, United Kingdom, 5Royal Brompton and Harefield NHS Foundation Trust, Department of Radiology, London, United Kingdom, 6Centre for Rheumatology, Royal Free and University College Medical School, London, United Kingdom

    Background/Purpose:  Pulmonary complications contribute substantially to systemic sclerosis (SSc) associated morbidity and are the most frequent disease-related cause of death. We explore predictors of clinically…
  • Abstract Number: 1746 • 2013 ACR/ARHP Annual Meeting

    Pericardial Effusions Are Not a Poor Prognostic Factor In Systemic Sclerosis Patients With Pulmonary Hypertension

    Elana J. Bernstein1, Jessica K. Gordon2, Wei-Ti Huang3 and Virginia D. Steen4, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Biostatistics, Hospital for Special Surgery, New York, NY, 4Department of Rheumatology, Georgetown University Medical Center, Washington, DC

    Background/Purpose: Pulmonary hypertension (PH) (defined as a mean pulmonary arterial pressure ≥ 25 mmHg on right heart catheterization) is a leading cause of death in…
  • Abstract Number: 822 • 2013 ACR/ARHP Annual Meeting

    Inhibition Of Casein Kinase II Reduces TGFβ Induced Fibroblast Activation and Ameliorates Experimental Fibrosis

    Yun Zhang, Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany

    Background/Purpose: Casein kinase-2 (CK2) is a highly conserved serine/threonine kinase. CK2 is a tetramer composed of 2 catalytic subunits (α or α’) and 2 β…
  • Abstract Number: 688 • 2013 ACR/ARHP Annual Meeting

    Minimal Clinically Important Investigations In Systemic Sclerosis

    Jessica Meijs1, Anne A. Schouffoer1, Nina Ajmone Marsan2, Maarten K. Ninaber3 and Tom W.J. Huizinga1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Cardiology, Leiden University Medical Center, Leiden, Netherlands, 3Pulmonology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The optimal management of Systemic Sclerosis (SSc) is a challenge due to the complexity of early diagnosis and identification of patients who are at…
  • Abstract Number: 674 • 2013 ACR/ARHP Annual Meeting

    Systemic Sclerosis Disease Subset Is a Better Predictor Of Long Term Outcome Than Autoantibody Profile

    Svetlana I. Nihtyanova1, Voon H. Ong2 and Christopher P. Denton3, 1Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, 2Department of Rheumatology, The Royal Free and University College Medical School, London, United Kingdom, 3Centre for Rheumatology, Royal Free and University College Medical School, London, United Kingdom

    Background/Purpose: Disease subset has been shown to strongly correlate with survival and risk of organ complications in patients with systemic sclerosis (SSc). Nevertheless evidence in…
  • Abstract Number: 675 • 2013 ACR/ARHP Annual Meeting

    Impact Of Male Sex On Survival In Systemic Sclerosis

    Haseena Hussein1, Peter Lee2, Cathy Chau3 and Sindhu R. Johnson4, 1Medicine, Toronto Scleroderma Research Program, Mount Sinai Hospital, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Lebovic Bldg, Mt. Sinai Hospital, Toronto, ON, Canada, 3Medicine, Toronto Scleroderma Program, Toronto Western Hospital, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 4Medicine, Division of Rheumatology, Toronto Western Hospital, University Health Network Pulmonary Hypertension Programme, Toronto General Hospital, Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Systemic sclerosis (SSc) has a female predominance with a female-to-male ratio of 3:1. Sex differences have been seen in many autoimmune diseases; however, little…
  • Abstract Number: 680 • 2013 ACR/ARHP Annual Meeting

    Diastolic Dysfunction Amongst Autoantibody Subgroups Of Patients With Diffuse Scleroderma

    Cory Perugino1, John Stephens2, Colin O'Rourke3 and Soumya Chatterjee4, 1Internal Medicine, Cleveland Clinic, Cleveland, OH, 2Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, 3Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, 4Rheumatic and Immunologic Ds, Cleveland Clinic, Cleveland, OH

    Background/Purpose: Scleroderma or systemic sclerosis (SSc) is an autoimmune disease characterized by microangiopathy, tissue hypoxia, and fibrosis. At least seven different autoantibodies have been identified…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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