ACR Meeting Abstracts

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Abstracts tagged "risk and systemic lupus erythematosus (SLE)"

  • Abstract Number: 89 • 2018 ACR/ARHP Annual Meeting

    Anti-Nuclear Antibodies (ANA) and Air Pollution: Ultrafine Particles and Ozone

    Sasha Bernatsky1, Shouao Wang2, May Y Choi3, Scott Weichenthal4, Marianne Hatzopoulou5, Marvin J. Fritzler6 and Audrey Smargiassi7, 1Divisions of Rheumatology and Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 2Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 3Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 4Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada, 5Civil and Mineral Engineering, University of Toronto, Toronto, ON, Canada, 6Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 7Public Health, Université de Montreal, Montreal, QC, Canada

    Background/Purpose: Previous studies have suggested links between air pollution (particularly PM2.5) and serum antibodies related to rheumatic diseases. No one has yet examined anti-nuclear antibody…
  • Abstract Number: 752 • 2018 ACR/ARHP Annual Meeting

    Prevalence and Predictors of Peripheral Vascular Disease in a Cohort of Systemic Lupus Erythematosus (SLE) Patients

    Ida Dzifa Dey1, Kelvin Acquaye2, Alfred Yawson3, Kofi Agyabeng4, Ernest Yorke5, Vincent Boima6 and Charles Mate-Kole7, 1Department of Medicine, Rheumatology Unit, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, 2Department of Psychology, School of Medicine and Dentistry, Accra, Ghana, 3Department of Community Health, School of Medicine and Dentistry, Accra, Ghana, 4Department of Community Health, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, 5Medicine, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, 6School of Medicine and Dentistry,University of Ghana, Accra, Ghana, 7Department of Psychology, School of Medicine and Dentistry, University of Ghana, Accra, Ghana

    Background/Purpose: Low Ankle-brachial index (ABPI) < 0.9 demonstrating peripheral vascular disease (PVD), is a marker of subclinical cardiovascular disease and it is an inexpensive and…
  • Abstract Number: 2670 • 2018 ACR/ARHP Annual Meeting

    Association of Hydroxychloroquine Use and Incident Atrial Fibrillation in Systemic Lupus Erythematosus: A Retrospective Study

    Alisha Gupta1, Aditya Joshi1, Mary Chester-Wasko2 and Tarun S. Sharma3, 1Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, 2Allegheny Health Network, Pittsburgh, PA, 3Rheumatology, Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, PA

    Background/Purpose: Hydroxychloroquine (HCQ) is a derivative of quinidine, a class 1a anti-arrhythmic agent used to prevent ventricular arrhythmias and recurrent atrial fibrillation (AFib). AFib occurs…
  • Abstract Number: 2805 • 2018 ACR/ARHP Annual Meeting

    Association of Dietary Quality Scores and Incident SLE in the Nurses’ Health Studies

    Medha Barbhaiya1, Bing Lu2, Sara K. Tedeschi2, Cianna Leatherwood3, Jeffrey A. Sparks3, Elizabeth Karlson2 and Karen Costenbader3, 1Rheumatology, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 2Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 3Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: High intake of antioxidants, fruits/vegetables, nuts and legumes and low intake of sodium, sweetened beverages, and red/processed meats may reduce inflammatory biomarkers and decrease…
  • Abstract Number: 2806 • 2018 ACR/ARHP Annual Meeting

    Childhood Physical and Sexual Abuse and Risk of Systemic Lupus Erythematosus Among African American Women

    Medha Barbhaiya1, Yvette Cozier2, Nelsy Castro-Webb2, Sara K. Tedeschi3, Cianna Leatherwood4, Lynn Rosenberg2 and Karen Costenbader4, 1Rheumatology, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 2Slone Epidemiology Center, Boston University, Boston, MA, 3Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: We and others have previously reported that post-traumatic stress disorder (PTSD) is associated with increased risk of developing SLE. We aimed to investigate the…
  • Abstract Number: 915 • 2017 ACR/ARHP Annual Meeting

    Pesticide Exposure and Risk of Systemic Lupus Erythematosus in an Urban Population of Predominantly African-American Women

    Jessica Williams1, Shun-Chiao Chang1, Corine Sinnette1, Susan Malspeis2, Christine G. Parks3, Elizabeth Karlson1, Patricia Fraser1 and Karen H. Costenbader1, 1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC

    Background/Purpose: Several studies have reported an association between exposure to pesticides and the risk of systemic lupus erythematosus (SLE). However, this association has not yet…
  • Abstract Number: 2651 • 2017 ACR/ARHP Annual Meeting

    Association of ITGAM Polymorphism rs1143679 with Susceptibility to Systemic Lupus Erythematosus in North Indian Population

    Sandeep Kumar1, Vikas Gupta1, Avadhesh Pratap2, Rajeev Singh3, Reena Kumari3, Amita Aggarwal1 and Ramnath Misra1, 1Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 2Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 3Biochemistry, King George Medical University, Lucknow, India

    Background/Purpose: ITGAM (Integrin-α-M, also known as CD11b) gene located at chromosome 16p11.2, encodes for the α-chain of Integrin-αMβ2, a leucocyte specific integrin receptor, also known…
  • Abstract Number: 2801 • 2016 ACR/ARHP Annual Meeting

    Predictors of Incident Episodes of Proteinuria Among Patients with Systemic Lupus Erythematosus

    Laurence S Magder1, Ali Duarte-Garcia2, Erik Barr3 and Michelle Petri4, 1Epidemiology and Public Health, Division of Rheumatology, School of Medicine, Johns Hopkins University, Baltimore, MD, 2Medicine, Tufts Medical Center, Boston, MA, 3Epidemiology, University of Maryland, Baltimore, MD, 4Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Lupus nephritis remains one of the most devastating SLE complications, occurring in over 50% of the patients.  It is important to identify clinical conditions…
  • Abstract Number: 2988 • 2016 ACR/ARHP Annual Meeting

    Cigarette Smoking Increases the Risk of Anti-Double-Stranded DNA Positive SLE Among Women in the Nurses’ Health Studies

    Medha Barbhaiya1, Sara Tedeschi2, Bing Lu1, Susan Malspeis3, Jeffrey A. Sparks3, Elizabeth W. Karlson1 and Karen H. Costenbader1, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: SLE is heterogeneous with subtypes characterized by different systemic manifestations and autoantibodies. Past studies suggest that smoking may be a risk factor for SLE,…
  • Abstract Number: 3159 • 2015 ACR/ARHP Annual Meeting

    Systemic Lupus Erythematosus Is a Risk Factor for Young Stroke: A Population-Based Cohort Study

    Elizabeth V Arkema1, Elisabet Svenungsson2, Christopher Sjöwall3 and Julia F Simard4,5, 1Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden, 2Department of Medicine, Karolinska Insitutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 3Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, 4Division of Epidemiology, Health Research and Policy Department, and Division of Immunology & Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, 5Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Previous studies indicate that individuals with SLE have a high risk of stroke but have not investigated when the highest risk occurs. We aimed…
  • Abstract Number: 708 • 2014 ACR/ARHP Annual Meeting

    Determining Risk Factors That Increase Hospitalizations in Patients with Systemic Lupus Erythematosis

    Hareth M. Madhoun1, Wael N. Jarjour2, Peter J. Embi3, Erinn M. Hade4 and W Neal Roberts Jr5, 1Rheumatology/Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, 2Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, 3Biomedical Informatics & Internal Medicine, The Ohio State University, Columbus, OH, 4College of Medicine Department of Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, OH, 5Dept of Internal Medicine, Division of Rheumatology, University of Louisville, Louisville, KY

    Background/Purpose Systemic lupus erythematosis (SLE) is a complex heterogeneous disease which can be associated with significant morbidity and mortality. Hospitalization and readmissions have garnered significant…
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