Abstracts tagged "risk and systemic lupus erythematosus (SLE)"

Abstract Number: 89 • 2018 ACR/ARHP Annual Meeting
Anti-Nuclear Antibodies (ANA) and Air Pollution: Ultrafine Particles and Ozone
Sasha Bernatsky¹, Shouao Wang², May Y Choi³, Scott Weichenthal⁴, Marianne Hatzopoulou⁵, Marvin J. Fritzler⁶ and Audrey Smargiassi⁷, ¹Divisions of Rheumatology and Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ²Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁴Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada, ⁵Civil and Mineral Engineering, University of Toronto, Toronto, ON, Canada, ⁶Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁷Public Health, Université de Montreal, Montreal, QC, Canada
Background/Purpose: Previous studies have suggested links between air pollution (particularly PM2.5) and serum antibodies related to rheumatic diseases. No one has yet examined anti-nuclear antibody…
Abstract Number: 752 • 2018 ACR/ARHP Annual Meeting
Prevalence and Predictors of Peripheral Vascular Disease in a Cohort of Systemic Lupus Erythematosus (SLE) Patients
Ida Dzifa Dey¹, Kelvin Acquaye², Alfred Yawson³, Kofi Agyabeng⁴, Ernest Yorke⁵, Vincent Boima⁶ and Charles Mate-Kole⁷, ¹Department of Medicine, Rheumatology Unit, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ²Department of Psychology, School of Medicine and Dentistry, Accra, Ghana, ³Department of Community Health, School of Medicine and Dentistry, Accra, Ghana, ⁴Department of Community Health, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ⁵Medicine, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ⁶School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ⁷Department of Psychology, School of Medicine and Dentistry, University of Ghana, Accra, Ghana
Background/Purpose: Low Ankle-brachial index (ABPI) < 0.9 demonstrating peripheral vascular disease (PVD), is a marker of subclinical cardiovascular disease and it is an inexpensive and…
Abstract Number: 2670 • 2018 ACR/ARHP Annual Meeting
Association of Hydroxychloroquine Use and Incident Atrial Fibrillation in Systemic Lupus Erythematosus: A Retrospective Study
Alisha Gupta¹, Aditya Joshi¹, Mary Chester-Wasko² and Tarun S. Sharma³, ¹Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, ²Allegheny Health Network, Pittsburgh, PA, ³Rheumatology, Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, PA
Background/Purpose: Hydroxychloroquine (HCQ) is a derivative of quinidine, a class 1a anti-arrhythmic agent used to prevent ventricular arrhythmias and recurrent atrial fibrillation (AFib). AFib occurs…
Abstract Number: 2805 • 2018 ACR/ARHP Annual Meeting
Association of Dietary Quality Scores and Incident SLE in the Nurses’ Health Studies
Medha Barbhaiya¹, Bing Lu², Sara K. Tedeschi², Cianna Leatherwood³, Jeffrey A. Sparks³, Elizabeth Karlson² and Karen Costenbader³, ¹Rheumatology, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ²Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: High intake of antioxidants, fruits/vegetables, nuts and legumes and low intake of sodium, sweetened beverages, and red/processed meats may reduce inflammatory biomarkers and decrease…
Abstract Number: 2806 • 2018 ACR/ARHP Annual Meeting
Childhood Physical and Sexual Abuse and Risk of Systemic Lupus Erythematosus Among African American Women
Medha Barbhaiya¹, Yvette Cozier², Nelsy Castro-Webb², Sara K. Tedeschi³, Cianna Leatherwood⁴, Lynn Rosenberg² and Karen Costenbader⁴, ¹Rheumatology, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ²Slone Epidemiology Center, Boston University, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: We and others have previously reported that post-traumatic stress disorder (PTSD) is associated with increased risk of developing SLE. We aimed to investigate the…
Abstract Number: 915 • 2017 ACR/ARHP Annual Meeting
Pesticide Exposure and Risk of Systemic Lupus Erythematosus in an Urban Population of Predominantly African-American Women
Jessica Williams¹, Shun-Chiao Chang¹, Corine Sinnette¹, Susan Malspeis², Christine G. Parks³, Elizabeth Karlson¹, Patricia Fraser¹ and Karen H. Costenbader¹, ¹Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC
Background/Purpose: Several studies have reported an association between exposure to pesticides and the risk of systemic lupus erythematosus (SLE). However, this association has not yet…
Abstract Number: 2651 • 2017 ACR/ARHP Annual Meeting
Association of ITGAM Polymorphism rs1143679 with Susceptibility to Systemic Lupus Erythematosus in North Indian Population
Sandeep Kumar¹, Vikas Gupta¹, Avadhesh Pratap², Rajeev Singh³, Reena Kumari³, Amita Aggarwal¹ and Ramnath Misra¹, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ³Biochemistry, King George Medical University, Lucknow, India
Background/Purpose: ITGAM (Integrin-α-M, also known as CD11b) gene located at chromosome 16p11.2, encodes for the α-chain of Integrin-αMβ2, a leucocyte specific integrin receptor, also known…
Abstract Number: 2801 • 2016 ACR/ARHP Annual Meeting
Predictors of Incident Episodes of Proteinuria Among Patients with Systemic Lupus Erythematosus
Laurence S Magder¹, Ali Duarte-Garcia², Erik Barr³ and Michelle Petri⁴, ¹Epidemiology and Public Health, Division of Rheumatology, School of Medicine, Johns Hopkins University, Baltimore, MD, ²Medicine, Tufts Medical Center, Boston, MA, ³Epidemiology, University of Maryland, Baltimore, MD, ⁴Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Lupus nephritis remains one of the most devastating SLE complications, occurring in over 50% of the patients. It is important to identify clinical conditions…
Abstract Number: 2988 • 2016 ACR/ARHP Annual Meeting
Cigarette Smoking Increases the Risk of Anti-Double-Stranded DNA Positive SLE Among Women in the Nurses’ Health Studies
Medha Barbhaiya¹, Sara Tedeschi², Bing Lu¹, Susan Malspeis³, Jeffrey A. Sparks³, Elizabeth W. Karlson¹ and Karen H. Costenbader¹, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: SLE is heterogeneous with subtypes characterized by different systemic manifestations and autoantibodies. Past studies suggest that smoking may be a risk factor for SLE,…
Abstract Number: 3159 • 2015 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus Is a Risk Factor for Young Stroke: A Population-Based Cohort Study
Elizabeth V Arkema¹, Elisabet Svenungsson², Christopher Sjöwall³ and Julia F Simard^4,5, ¹Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden, ²Department of Medicine, Karolinska Insitutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ³Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, ⁴Division of Epidemiology, Health Research and Policy Department, and Division of Immunology & Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, ⁵Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Previous studies indicate that individuals with SLE have a high risk of stroke but have not investigated when the highest risk occurs. We aimed…
Abstract Number: 708 • 2014 ACR/ARHP Annual Meeting
Determining Risk Factors That Increase Hospitalizations in Patients with Systemic Lupus Erythematosis
Hareth M. Madhoun¹, Wael N. Jarjour², Peter J. Embi³, Erinn M. Hade⁴ and W Neal Roberts Jr⁵, ¹Rheumatology/Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, ²Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, ³Biomedical Informatics & Internal Medicine, The Ohio State University, Columbus, OH, ⁴College of Medicine Department of Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Dept of Internal Medicine, Division of Rheumatology, University of Louisville, Louisville, KY
Background/Purpose Systemic lupus erythematosis (SLE) is a complex heterogeneous disease which can be associated with significant morbidity and mortality. Hospitalization and readmissions have garnered significant…