ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 0835 • ACR Convergence 2023

    Abatacept in Individuals at Risk of Developing Rheumatoid Arthritis: Results from the Arthritis Prevention in the Pre-clinical Phase of RA with Abatacept (APIPPRA) Trial

    Andrew Cope1, Marianna Jasenecova2, Joana Vasconcelos3, Andrew Filer4, Karim Raza5, Sumera Qureshi2, Maria Antonietta D'Agostino6, Iain McInnes7, John Isaacs8, Arthur Pratt9, Benjamin A Fisher4, Christopher Buckley10, Paul Emery11, Pauline Ho12, Maya Buch13, Coziana Ciurtin14, René Toes15, Thomas Huizinga15, Dirkjan van Schaardenburg16, Caroline Caroline17 and Toby Prevost3, 1King's College London, London, United Kingdom, 2Centre for Rheumatic Diseases, King's College London, London, United Kingdom, 3Nightingale-Saunders Clinical Trials & Epidemiology Unit, King's College London, London, United Kingdom, 4University of Birmingham, Birmingham, United Kingdom, 5Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 6Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy, 7University of Glasgow, Glasgow, United Kingdom, 8Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom, 9Translational & Clinical Research Institute, University of Newcastle, Newcastle, United Kingdom, 10University of Oxford, Oxford, United Kingdom, 11Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 12Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 13University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom, 14Centre for Rheumatology Research, University College London, London, United Kingdom, 15Leiden University Medical Center, Leiden, Netherlands, 16Reade, Amsterdam, Netherlands, 17King's Clinical Trials Unit, King's College London, London, United Kingdom

    Background/Purpose: The definition of higher risk states for rheumatoid arthritis (RA) has been refined in more recent years through inclusion of serum autoantibodies and symptom…
  • Abstract Number: 0982 • ACR Convergence 2023

    Systemic Autoimmune Rheumatic Diseases (SARD) in the Agricultural Health Study Cohort: Rates of Rheumatoid Arthritis (RA) and Other SARD Among Medicare-linked Participants

    Christine Parks1, Karen Costenbader2, Laura Beane Freeman3, Jonathan Hofmann3 and Dale Sandler4, 1Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 2Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 4Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC

    Background/Purpose: Some systemic autoimmune rheumatic diseases (SARD), such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), have been associated with farming, specific pesticides, and…
  • Abstract Number: 1034 • ACR Convergence 2023

    The Relationship Between the Extent of Ground Glass to Fibrosis Ratio and Treatment Response to Immunomodulatory Therapy in Three Separate Autoimmune Interstitial Lung Disease Cohorts

    Scott Matson1, Stephen Humphries2, joyce Lee3, Michael Roth4, Donald Tashkin4, Grace Kim4, Jonathan Goldin4, Mei Leng4 and Elizabeth Volkmann4, 1University of Kansas School of Medicine, Kansas City, MO, 2National Jewish Health, Denver, CO, 3University of Colorado Anschutz Campus, Denver, CO, 4University of California Los Angeles, Los Angeles, CA

    Background/Purpose: For patients with autoimmune interstitial lung disease (ILD), the clinician's interpretation of the extent of ground glass relative to fibrosis on imaging often influences…
  • Abstract Number: 1265 • ACR Convergence 2023

    Changes in the Endocannabinoid Tone in Rheumatoid Arthritis and Osteoarthritis – Discovery of a Novel Target for the Treatment of Pain and Inflammation?

    Jost Klawitter1, Andrew Clauw1, Jennifer Seifert1, Jelena Klawitter1, Bridget Tompson1, Cristina Sempio1, Uwe Christians1 and Larry Moreland2, 1University of Colorado Anschutz Medical Campus, Aurora, CO, 2University of Colorado, Denver, CO

    Background/Purpose: Inflammation is a complicated physiological process that results in a variety of disorders. Several inflammatory mediators are produced during this process, which is responsible…
  • Abstract Number: 1281 • ACR Convergence 2023

    Risk of Cancer in Patients with Rheumatoid Arthritis Under Tocilizumab: Data from the French National Registry REGATE

    JACQUES MOREL1, Amélie Wetzman2, Daniel Wendling3, Martin Soubrier4, Olivier Roth5, Jacques-Eric Gottenberg6, Philippe Goupille7, Xavier Mariette8 and Cedric Lukas9, 1Protocole thérapeutique immuno-rhumatologie, Montpellier, France, 2CHU and University of Montpellier, Narbonne, France, 3Besançon University Hospital, Besançon, France, 4Gabriel-Montpied Hospital, Clermont-ferrand, France, 5Saint Joseph Hospital, Marseille, France, 6Rheumatology Department, Strasbourg University Hospital, Strasbourg, France, 7CHU and University of Tours, Tours, France, 8Université Paris-Saclay, Le Kremlin-Bicêtre, France, 9CHU Montpellier, Montpellier, France

    Background/Purpose: Our study aimed to estimate the incidence and risk factors of cancer among rheumatoid arthritis (RA) patients treated with tocilizumab (TCZ) and followed for…
  • Abstract Number: 1297 • ACR Convergence 2023

    COVID-19 Vaccination-related Delayed Adverse Events Among Patients with Rheumatoid Arthritis: Results from the COVAD Study

    Mrinalini Dey1, Bohdana Doskaliuk2, Ioannis Parodis3, Julius Lindblom3, Chris Wincup4, Mrudula Joshi5, Dey Dzifa6, Esha Kadam7, Parikshit Sen8, Samuel Shinjo9, Arvind Nune10, Nelly Ziade11, Yi-Ming Chen12, Lisa Traboco13, CARLOS ENRIQUE TORO GUTIERREZ14, COVAD Study Group15, Rohit Aggarwal16, Vikas Agarwal17, Latika Gupta18 and Elena Nikiphorou19, 1Queen Elizabeth Hospital, London, United Kingdom; University of Liverpool, Liverpool, United Kingdom, 2SHEI "Ivano-Frankivsk national medical university", Ivano-Frankivsk, Ukraine, 3Karolinska Institutet, Stockholm, Sweden, 4King's College Hospital, London, United Kingdom, 5Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 6Department of Medicine and Therapeutics, University of Ghana School of Medicine and Dentistry, College of Health Sciences, Korle-Bu, Accra, Ghana, 7Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, 8Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 9Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 10Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, 11Saint-Joseph University, Beirut, Lebanon, 12Taichung Veterans General Hospital, Taichung, Taiwan, 13University of the Philippines - Manila, St Luke's Medical Center - Bonifacio Global City, Paranaque, Manila, Philippines, 14Centro de Estudios de Reumatología y Dermatología SAS, Cali, Colombia, 15-, -, 16University of Pittsburgh, Pittsburgh, PA, 17Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 18Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 19King's College London, London, United Kingdom

    Background/Purpose: COVID-19 vaccines have been proven to be safe in the healthy population. Data on longer-term AEs in people with autoimmune diseases (AIDs), including rheumatoid…
  • Abstract Number: 1313 • ACR Convergence 2023

    Remotely Supervised Weight Loss and Exercise Training Improves Disease Activity and Patient Reported Outcomes in Older Patients with Rheumatoid Arthritis

    Brian Andonian, Leanna Ross, Alyssa Sudnick, Johanna Johnson, Carl Pieper, Connie Bales, Kathryn Porter Starr, William Kraus and Kim Huffman, Duke University, Durham, NC

    Background/Purpose: Older persons with rheumatoid arthritis (RA) are at increased risk for sarcopenic obesity, physical disability, adverse drug events, and cardiovascular disease; thus, there is…
  • Abstract Number: 1330 • ACR Convergence 2023

    Certolizumab-pegol, Abatacept, Tocilizumab or Active Conventional Therapy in Early Rheumatoid Arthritis: 48 Week Patient-reported Outcomes of the NORD-STAR Trial

    John Lampa1, Dan Nordstrom2, Ronald van Vollenhoven3, Merete Hetland4, Espen A Haavardsholm5, Mikkel Østergaard6, Anna Rudin7, Marte Schrumpf Heiberg5, Michael Nurmohamed3, Bjorn Gudbjornsson8, Kristina Lend9, Kim Hørslev-Petersen10, Tuulikki Sokka-Isler11, Gerdur Maria Grondal12, Simon Krabbe13, Joakim Lindqvist14, Anna-Karin Hultgård Ekwall15, Daniel Glinatsi16, Meliha Kapetanovic17, Cidem Gentline14, Anna-Birgitte Aga18, Heikki Relas2, Tove Lorenzen19, Giovanni Cagnotto20, Johan Back21, Oliver Hendricks22, Bas Dijkshoorn23, Kajsa Öberg24, Maud-Kristine Aga Ljoså25, Eli Brodin26, Hanne Merete Lindegaard27, Annika Söderbergh28, Milad Rizk29, Alf Kastbom30, Per Larsson31, Line Uhrenholt32, Søren Just33, David J Stevens34, Trine B Laurberg35, Gunnstein Bakland36, Inge Olsen37, Joseph Sexton18 and Till Uhlig18, 1Stockholm County, Hãsselby, Sweden, 2Helsinki University Hospital, Helsinki, Finland, 3Amsterdam University Medical Centers, Amsterdam, Netherlands, 4Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, 5Diakonhjemmet Hospital, Oslo, Norway, 6Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 7Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 8Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 9Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 10University of Southern Denmark, Odense, Denmark, 11Jyvaskyla Central Hospital, Jyväskylä, Finland, 12Department for Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, 13Herlev-Gentofte University Hospital, Herlev, Denmark, 14Karolinska University Hospital, Stockholm, Sweden, 15Department of Rheumatology and Inflammation research, Sahlgrenska Academy, University of Gothenburg, Kullavik, Sweden, 16Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Sweden, 17Lund University and Skåne University Hospital, Lund, Sweden, 18Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 19Silkeborg University Hospital, Silkeborg, Denmark, 20Skåne University Hospital, Lund, Sweden, 21Uppsala University Hospital, Uppsala, Sweden, 22Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, 23Amsterdam Rheumatology and Immunology Center, Location Reade, Amsterdam, Netherlands, 24Falu Hospital, Falun, Sweden, 25Ålesund Hospital, Ålesund, Norway, 26Haukeland University Hospital, Bergen, Norway, 27Odense Hospital, Odense, Denmark, 28Örebro University Hospital, Örebro, Sweden, 29Västmanlands Hospital Västerås, Västerås, Sweden, 30Linköping University, Linköping, Sweden, 31Academic Specialist Center, Stockholm, Sweden, 32Aalborg University Hospital, Aalborg, Denmark, 33Section of Rheumatology, Department of Medicine, Odense University Hospital – Svendborg Hospital, Odense, Denmark, 34St. Olavs Hospital, Trondheim, Norway, 35Aarhus University Hospital, Aarhus, Denmark, 36University Hospital of North Norway, Tromsø, Norway, 37Oslo University Hospital, Oslo, Norway

    Background/Purpose: The optimal first-line treatment of patients with early rheumatoid arthritis (eRA) is not established. Methods: In this investigator-initiated, randomized, open-label study (NCT01491815), patients with…
  • Abstract Number: 1347 • ACR Convergence 2023

    Continuing Biologic DMARDs During Pregnancy in Women with Rheumatic Disease Was Not Associated with Increased Unfavorable Pregnancy Outcomes, Serious Infections, and Adverse Effects of Vaccination

    Hiromi Shimada1, Risa Wakiya2, Shusaku Nakashima2, Taichi Miyagi3, Yusuke Ushio4, Koichi Sugihara5, Rina Mino6, Mao Mizusaki2, Kanako Chujo7, Ryoko Kagawa4, Hayamasa Yamaguchi4, Tomohiro Kameda2 and Hiroaki Dobashi2, 1Kagawa University, Kagawa, Japan, 2Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan, 3Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kidagun, Japan, 4Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Miki-cho, Kita-gun, Japan, 5Kagawa University, Miki-cho, Kita-gun, Japan, 6Kagawa University, Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa, Japan, 7Kagawa University, Miki, Kita District, Kagawa, Japan

    Background/Purpose: It is important to control disease activity during pregnancy in women with rheumatic diseases because its exacerbation is associated with increased adverse pregnancy outcomes.…
  • Abstract Number: 1676 • ACR Convergence 2023

    Tofacitinib Accelerates in Vitro Clot Formation and Delays Clot Lysis in Rheumatoid Arthritis Blood by Enhancement of Macrophage TLR4 Mediated Cytokine Responses- a New Angle on Thrombosis with JAKi in Rheumatology

    Paula David1, Thomas Macleod2, Yu Shi3, Payal Ganguly1, Cedric Duval3, Mark Harland1, Chi Wong1, Benazir Saleem4 and Dennis McGonagle5, 1University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom, 2University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 3Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom, 4Leeds Teaching Hospitals NHS Trust, Rheumatology, Chapel Allerton Hospital, Leeds, United Kingdom, 5Leeds Biomedical Research Centre, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Rheumatoid Arthritis (RA) patients treated with Janus Kinase inhibitors (JAKi) have reportedly higher venous thromboembolism (VTE) risk and atherosclerotic-related complications including myocardial infarction (1).Although…
  • Abstract Number: 1731 • ACR Convergence 2023

    A Competitive Inhibitor of MOART Showed Potent Therapeutic Effects in a Mouse Model of Collagen-induced Arthritis

    Sujin Park1, DongWoo Kang2, Haein An1, Eunji Hong1, Kwiyeom Yoon2, MinWoo Kim2, Hwajung Kim2 and Seong Jin Kim2, 1GILO Institute, GILO Foundation, Seoul, South Korea, 2Medpacto Inc., Seoul, South Korea

    Background/Purpose: Despite tumor necrosis factor (TNF) inhibitors and Jak kinase inhibitors (JKI) have shown a significant advance in the treatment of rheumatoid arthritis (RA) however,…
  • Abstract Number: 1747 • ACR Convergence 2023

    A Newly Described Cytokine interleukin-40 Is Increased in the Serum of Individuals At-risk of Rheumatoid Arthritis and Induces an Inflammatory Response in Mononuclear Cells

    Adela Navratilova1, Klára Prajzlerová2, Nora Růžičková3, Karel Pavelka4, Jiri Vencovsky5, Ladislav Senolt6, Maria Filkova3 and Lucie Andrés Cerezo3, 1Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Hlavní město Praha, Czech Republic, 2Institute of Rheumatology, Prague, Czech Republic, 3Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 4Institut of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Praha, Czech Republic, 5Institute of Rheumatology, Prague, Czech Republic, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 6Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Praha, Czech Republic

    Background/Purpose: Interleukin-40 (IL-40) is a newly described cytokine related to malignancies and immunity function. We have previously shown that IL-40 is up-regulated in early stages…
  • Abstract Number: 1763 • ACR Convergence 2023

    Asthma Severity Is Associated Increased Serum Anti-cyclic Antibody Level at Baseline and in Increase During Longitudinal Follow-up

    Drayton Rorah1, Linh Ngo2, Mario Castro2, Kristen Demoruelle3 and Scott Matson4, 1University of Kansas Medical Center, Kansas City, KS, 2University of Kansas School of Medicine, Kansas City, KS, 3University of Colorado Anschutz Medical Campus, Aurora, CO, 4University of Kansas School of Medicine, Kansas City, MO

    Background/Purpose: The lung airways have been implicated in the pathogenesis of RA. RA-associated autoantibodies, including anti-cyclic citrullinated peptide (anti-CCP) antibodies are found to be generated…
  • Abstract Number: 1847 • ACR Convergence 2023

    Influence of Seasonal Changes on Adherence in Rheumatoid Arthritis Patients

    Cody Schmidt, Kunal Patel, Samantha Delgado, Guy Cozzi, Elisea Avalos-Reyes, W. Cliff Rutter, Rashmi Grover, Lucia Feczko, Will Cavers and Kjel Johnson, CVS Health, Woonsocket, RI

    Background/Purpose: Rheumatoid arthritis (RA) symptoms are suspected to be linked with exposure to colder environments. Previous studies on RA and seasonality have focused on RA…
  • Abstract Number: 1911 • ACR Convergence 2023

    Using the Technology Acceptance Model to Assess Physician Perceptions and Experiences Using the Rheumatoid Arthritis-Patient-Reported Outcomes Dashboard: Mixed-Methods Study

    Catherine Nasrallah1, Cherish Wilson2, Alicia Hamblin1, Lindsay Jacobsohn1, Cammie Young3, Cammie Young3, Mary Nakamura4, Andrew Gross1, Judith Ashouri1, Mehrdad Matloubian1, Jinoos Yazdany1 and Gabriela Schmajuk2, 1University of California San Francisco, San Francisco, CA, 2UCSF / SFVA, San Francisco, CA, 3University of California San Francisco, Oakland, CA, 4UCSF/SFVAHCS, San Francisco, CA

    Background/Purpose: Improving shared decision-making using a treat-to-target approach, including the use of patient reported outcomes (PROs), is important to providing high quality care for rheumatoid…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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