ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 1016 • ACR Convergence 2024

    Pharmacoequity of DMARDs Among Adults with Rheumatoid Arthritis in the U.S

    Ashkan Ara1, Matthew Chenoweth2, Srikanth Kadiyala2, Utibe Essien3 and Christopher Scannell3, 1Division of Rheumatology, David Geffen School of Medicine at the University of California, Los Angeles (UCLA), Los Angeles, 2Department of Health Policy and Management, Fielding School of Public Health at UCLA, Los Angeles, 3Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles

    Background/Purpose: Long-term management of rheumatoid arthritis (RA) relies on disease-modifying antirheumatic drugs (DMARDs), including conventional synthetic (csDMARDs), biologic (bDMARDs), and targeted synthetic (tsDMARDs). About 40%…
  • Abstract Number: 1077 • ACR Convergence 2024

    Pragmatic Quantitative Rheumatologist 0–10 Visual Numeric Scale Estimates of Inflammation, Damage, and Patient Distress Have Face Validity and May Be as Informative as Formal 28 Joint Counts in Rheumatoid Arthritis

    Theodore Pincus1, tengfei Li2 and Juan Schmukler1, 1Rush University Medical Center, Chicago, IL, 2Rush University Medical Center, washington dc

    Background/Purpose: A 28 joint count of swelling (SJC), tenderness/pain on motion (TJC), and deformity/limited motion (DJC), is recommended to assess rheumatoid arthritis (RA) patient status.…
  • Abstract Number: 1330 • ACR Convergence 2024

    Increased Levels of F-calprotectin in Patients with Early Rheumatoid Arthritis at Diagnosis

    Jon Einarsson1, Katarina Friberger Pajalic2, Caroline Bengtsson3, Carmen Roseman4, Ellen Landgren1, Elisabeth Mogard5, Elisabet Lindqvist5, Tor Olofsson4, Johan Karlsson Wallman6 and Meliha C Kapetanovic4, and Lund Arthritis Research Group (LARG), 1Lund University, Department of Clinical Sciences Lund, section of rheumatology and Skåne University Hospital Lund, Sweden, Lund, Skane Lan, Sweden, 2Lunds University, Department of clinical sciences, section of Rheumatology Malmö and Skåne University Hospital Malmö, Sweden, Malmö, Sweden, 3Skåne University Hospital Lund, Sweden, Lund, Sweden, 4Lund University, Department of Clinical Sciences Lund, section of rheumatology and Skåne University Hospital Lund, Sweden, Lund, Sweden, 5Lund University, Department of Clinical Sciences Lund, Section of Rheumatology and Skåne University Hospital, Lund, Sweden, Lund, Sweden, 6Lund University, Department of Clinical Sciences Lund, Section of Rheumatology and Skåne University Hospital, Lund, Sweden, Lund, Skane Lan, Sweden

    Background/Purpose: Alterations in gut microbiota (dysbiosis) may contribute to the development of rheumatoid arthritis (RA). Elevated fecal calprotectin (F-calprotectin), an established biomarker of gut inflammation, has…
  • Abstract Number: 1346 • ACR Convergence 2024

    Early Diagnosis of Rheumatoid Arthritis: Role of Joint Ultrasound Assessment

    Cristina Corrales Selaya1, Carmen Secada Gómez2, Sabela Fernandez-Aguado3, Isla Morante-bolado4, Montserrat Santos-gomez5, Sara Alonso-Castro6, Virginia Portilla-González7, Ricardo Blanco-Alonso8, Javier Rueda Gotor4 and alfonso Corrales-Martínez9, 1Rheumatology, Marques de Valdecilla University Hospital. IDIVAL, Santander, Cantabria, Spain, 2Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Hospital Universitario Montecelo, Pontevedra, Galicia, Spain, 4Hospital Sierrallana, Torrelavega, Cantabria, Spain, 5Hospital universitario Central de Asturias, Oviedo, Asturias, Spain, 6Hospital Universitario Central de Asturias., Oviedo, Asturias, Spain, 7Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, 8Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain, 9Hospital Universitario Marques de Valdecilla, Santander, Spain

    Background/Purpose: Early diagnosis of Rheumatoid Arthritis (RA) is essential to establish treatment to improve long-term disease outcomes. Musculoskeletal ultrasound (US) is able to detect subclinical…
  • Abstract Number: 1362 • ACR Convergence 2024

    Comparative Effectiveness of Upadacitinib versus Other JAK Inhibitors in Patients with Rheumatoid Arthritis in a Global Real-World Setting

    Peter C. Taylor1, Aditi Kadakia2, Jack Milligan3, Sander Strengholt2, Oliver Howell3, Pankaj Patel2, Sophie Barlow3 and Roberto Caporali4, 1University of Oxford, Oxford, United Kingdom, 2AbbVie Inc., North Chicago, IL, 3Adelphi Real World, Bollington, United Kingdom, 4Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milan, Italy

    Background/Purpose: Network meta-analyses of phase 3 clinical trial data involving JAK inhibitor (JAKi)-treated patients with RA and an inadequate response to conventional synthetic DMARDs showed…
  • Abstract Number: 1378 • ACR Convergence 2024

    Tocilizumab Effect on the Three Pathways of the Complement System in Patients with Rheumatoid Arthritis

    Marta Hernández-Díaz1, Iván Ferraz-Amaro2, Sergio Santos-Concepción3, Javier Castro3, Vanesa Hernandez4, Beatriz Tejera Segura5, Cristina Luna6, Esmeralda Delgado-Frías2 and Federico Diaz-González2, 1Hospital Universitario de Canarias, SANTA CRUZ DE TENERIFE, Spain, 2Hospital Universitario de Canarias, La Laguna, Spain, 3Universidad de La Laguna, La Laguna, Spain, 4Rheumatology department. Hospital Universitario de Canarias, La Laguna, Spain, 5Rheumatology Department. Hospital Universitario Insular de Gran Canaria, Las palmas, Spain, 6Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz, Spain

    Background/Purpose: Tocilizumab (TCZ) is used in diseases characterized by markedly elevated inflammatory markers and elevated pro-inflammatory cytokines like rheumatoid arthritis (RA), juvenile idiopathic arthritis and…
  • Abstract Number: 1395 • ACR Convergence 2024

    Effects of Butyrate Supplementation in Modulation of Gut Microbiome and Its Metabolites in New Onset Rheumatoid Arthritis

    Rebecca Blank1, Alba Boix-Amoros2, Erin Reilly3, Kevin Bu4, Ian Cunningham5, Renuka Nayak6, Andrew Patterson7, Jose Clemente4 and Jose Scher8, 1NYU, New York, NY, 2Icahn School of Medicine, New York, NY, 3Penn State, State Park, PA, 4Icahn School of Medicine at Mount Sinai, New York, NY, 5NYU Langone Health, New York, NY, 6University of California, San Francisco (UCSF), San Francisco, CA, 7Penn State University, State College, PA, 8New York University School of Medicine, New York, NY

    Background/Purpose: The gut microbiome and its metabolites are dysregulated in RA and other immune-mediated inflammatory diseases. However, the significance of this observation and its implications…
  • Abstract Number: 1663 • ACR Convergence 2024

    Notch—mediated Fibrogenic Activation Is a Spatial Determinant of RA Treatment Response

    Kartik Bhamidipati1, Ce Gao1, Ksenia Anufrieva2, Shideh Kazerounian3, Roopa Madhu4, Miles Tran1, Vikram Khedgikar1, Sonia Presti1, Anna Helena Jonsson5, ilya Korsunsky1 and Kevin Wei6, 1Brigham and Women's Hospital, Boston, MA, 2BWH, Cambridge, MA, 3Brigham & Women's Hospital, Boston, MA, 4Brigham and Women's Hospital, Brookline, MA, 5University of Colorado School of Medicine, Aurora, CO, 6Brigham and Women's Hospital at Harvard Medical School, Boston, MA

    Background/Purpose: In RA, poor treatment response has been linked to a fibroid synovial tissue phenotype, characterized by lack of immune cell infiltration and an expansion…
  • Abstract Number: 1745 • ACR Convergence 2024

    Use of Statins and Its Association with Major Adverse Cardiovascular Outcomes with Tofacitinib versus TNF Inhibitors in a Risk-Enriched Population of Patients with Rheumatoid Arthritis

    Jon Giles1, christina Charles-Schoeman2, Maya H. Buch3, Maxime Dougados4, Zoltan Szekanecz5, Ted Mikuls6, Steven R Ytterberg7, Gary G Koch8, Kenneth Kwok9, Mary Jane Cadatal10, Sujatha Menon11, Yan Chen12, Annette M Diehl12, Jose L Rivas13, Arne Yndestad14 and Deepak L Bhatt15, 1Cedars Sinai Medical Center, Los Angeles, CA, 2UCLA Medical Center, Santa Monica, CA, 3Division of Musculoskeletal & Dermatological Sciences, University of Manchester, and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom, 4Université de Paris; Department of Rheumatology, Hôpital Cochin; Assistance Publique-Hôpitaux de Paris; and INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France, 5Department of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, 6University of Nebraska Medical Center, Omaha, NE, 7Division of Rheumatology, Mayo Clinic, Rochester, MN, 8Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 9Pfizer Inc, New York, NY, 10Pfizer Inc, Manila, Philippines, 11Pfizer Inc, Groton, CT, 12Pfizer Inc, Collegeville, PA, 13Pfizer SLU, Madrid, Spain, 14Pfizer Inc, Oslo, Norway, 15Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY

    Background/Purpose: ORAL Surveillance (NCT02092467; a post-authorization safety study of tofacitinib 5 and 10 mg twice daily [BID] vs TNF inhibitors [TNFi]) found higher incidence of…
  • Abstract Number: 1877 • ACR Convergence 2024

    Trends in Rheumatoid Arthritis Incidence, Prevalence, DALY and Death Rates (1991-2021) in the United States: A Comprehensive Analysis of State-Level Disparities

    Aviraag Vijaya Prakash1, Vishwas Hosur Ravishankar2, Aishwarya Sudheer1 and Paramarajan Piranavan3, 1Saint Vincent Hospital, Department of Internal Medicine, Worcester, MA, 2St Vincents Hospital, Worcester, MA, 3University of Kentucky, Division of Rheumatology, Lexington, KY

    Background/Purpose: Rheumatoid Arthritis (RA) exhibits varied epidemiological patterns across states in the United States, influencing disability-adjusted life years (DALYs), incidence rates, prevalence, and mortality. This…
  • Abstract Number: 1959 • ACR Convergence 2024

    A 3-arm, Randomized, Open-label, Parallel Active Controlled, Multicentre International Study to Compare the Response of Ultrasound-assessed Synovitis to Baricitinib, Alone and Combined with Methotrexate versus Etanercept in Rheumatoid Arthritis Patients

    ESPERANZA NAREDO1, Otto Olivas-Vergara2, Pablo E. Borges2, Sheila Recuero-Díaz2, Fernando Saraiva3, Joana Martinho3, Filipa Costa3, Catarina Tenazinha3, Margarida Monteiro3, Ana Teresa Melo3, Ana Rodriguez-García4, Carlos A. Guillén-Astete5, Boris A. Blanco-Cáceres4, Alina L. Boteanu4, Antonio Mera-Varela6, Eva Pérez Pampín6, Yolanda López Golán6, Cristina Campos Fernández7, Jorge Juan Fragío Gíl7, roxana gonzalez mazarío7, Juan José De Agustín8, Gustavo Añez Sturchio9, Luis Coronel Tarancon8, Esther Vicente-rabaneda10, Santos Castañeda10, Irene Llorente-Cubas10, Maria S. Stoenoiu11, NZEUSSEU TOUKAP Adrien12, Ilaria Padovano13, Helene Gouze13, Ariane Leboime13, Maxime Breban14, Jaqueline Uson15, Virginia Villaverde16, Martina Steiner17, Cristina Vergara Dangond17, Maria Beatriz Paredes Romero17, Santiago Muñoz Fernández18, Carolina Pérez-García19, Juan Antonio Meraz-Ostiz19, Stephanie Finzel20, Anna-Maria Kanne21, Aránzazu Mediero22, Carmen Herencia23, Gabriel Herrero-Beaumont24 and Raquel Largo22, 1Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, 2Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD, Madrid, Spain, 3Rheumatology Department, Unidade Local de Saúde de Santa Maria. Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Lisbon, Portugal, 4Rheumatology Department. Ramón y Cajal University Hospital, Madrid, Spain, 5Rheumatology Department. Ramon y Cajal University Hospital, Madrid, Spain, 6Department of Rheumatology. Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain, 7Department of Rheumatology. Hospital General Universitario de Valencia, Valencia, Spain, 8Image and Technics Unit, Department of Rheumatology. Hospital Universitari Vall d’Hebron, Barcelona, Spain, 9Department of Rheumatology. Hospital Arnau de Vilanova, Lleida, Spain, 10Hospital Universitario de La Princesa, Madrid, Spain, 11Cliniques Universitaires Saint-Luc, Brussels, Belgium, 12Institut de Recherche Expérimentale et Clinique, Cliniques universitaires Saint-Luc, Université catholique de Louvain, St.-Lambrechts-Woluwe, Belgium, 13Departement of Rheumatology, Hopital Ambroise Paré, Boulogne-Billancourt, Spain, 14Departement of Rheumatology, Hopital Ambroise Paré, Departement of Rheumatology, Hopital Ambroise Paré, Spain, 15Department of Rheumatology, Hospital Universitario de Móstoles. University Rey Juan Carlos, Madrid, Spain, 16Department of Rheumatology, Hospital Universitario de Móstoles, Madrid, Spain, 17Department of Rheumatology. Hospital Universitario Infanta Sofía., Madrid, Spain, 18Hospital Universitario Infanta Sofía. Universidad Europea de Madrid, Madrid, Spain, 19Department of Rheumatology, Hospital del Mar of Barcelona, Barcelona, Spain, 20Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg, DE, Freiburg im Breisgau, Germany, 21Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany, 22Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz, Madrid, Spain, 23Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz, M, Spain, 24Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain

    Background/Purpose: To demonstrate non-inferiority of the response of musculoskeletal ultrasound (MSKUS)-assessed synovitis to baricitinib, alone and plus MTX vs. etanercept plus MTX in patients with…
  • Abstract Number: 2169 • ACR Convergence 2024

    Different Trajectories of Patient Reported Outcomes in Patients with RA in a Stable Phase of Disease – an Observational Study

    Paul Studenic1, Nadine Schwab2, Günther Zauner2, Thi Lan Vi Tran3 and Helga Lechner-Radner4, 1Medical University Vienna, Department of Internal Medicine III, Division of Rheumatology, Vienna, Austria, Vienna, Austria, 2dwh GmbH, simulation services, Vienna, Austria & Institute of Information Systems Engineering, TU Wien, Vienna, Austria, 3Medical University of Vienna, Vienna, Austria, 4Medical University Vienna, Department of Internal Medicine III, Division of Rheumatology, Vienna, Austria

    Background/Purpose: In patients with rheumatoid arthritis (RA), we often see a disconnect between patient and evaluator perceived disease activity. In this study we aim to…
  • Abstract Number: 2226 • ACR Convergence 2024

    Site-specific Differences in the Association of Non-vertebral Major Osteoporotic Fractures and Rheumatoid Arthritis

    John Chen1, Malini Chandra2, Laura Carbone3, John Schousboe4, Elisha Garcia2 and Joan Lo2, 1Kaiser Permanente Oakland Medical Center, Oakland, CA, 2Kaiser Permanente, Oakland, CA, 3Augusta University, Augusta, GA, 4University of Minnesota, Minneapolis, MN

    Background/Purpose: Rheumatoid arthritis (RA) and osteoporosis are both chronic, potentially debilitating conditions that frequently co-occur, affecting millions of people annually. Among those with osteoporosis, RA…
  • Abstract Number: 2242 • ACR Convergence 2024

    A Cross-sectional Study on Predictors of COVID-19 Infection, Admission and Mortality and Effect of Immunomodulating Treatments in Rheumatoid Arthritis

    Mohammad Movahedi1, Elliot Hepworth2, Angela Cesta3, Xiuying Li3, Claire Bombardier4 and Sibel Aydin5, and OBRI investogators, 1Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 2University of Ottawa, Ottawa, ON, Canada, 3UHN, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5Ottawa Hospital Research Institute, Ottawa, ON, Canada

    Background/Purpose: COVID-19 infection frequently leads to a cytokine storm, which has successfully been treated with some immunomodulating therapies according to observational studies. Interestingly, treatments investigated…
  • Abstract Number: 2262 • ACR Convergence 2024

    Window of Opportunity in the Treatment of Rheumatoid Arthritis – Interstitial Lung Disease with Abatacept. National Multicenter Study of 526 Patients

    Ana Serrano-Combarro1, Belén Atienza-Mateo2, Libe Ibarrola Paino3, Ivette Casafont-Sole4, Jesús Loarce5, Juan María Blanco Madrigal6, Santos Castañeda7, Rafaela Ortega-Castro8, Natalia Mena Vázquez9, Nuria Vegas Revenga10, Lucía Domínguez Casas11, Cilia Peralta Ginés12, Miriam Retuerto Guerrero13, Lorena Pérez Albadalejo14, Rubén López Sánchez15, MARIA GUADALUPE MANZANO CANABAL16, Anahy Maria Brandy-Garcia17, Patricia Lopez Viejo18, Gema Bonilla19, Olga Maíz Alonso20, Carmen Carrasco-Cubero21, Marta Garijo Bufort22, Ana Urruticoechea Arana23, Sergi Ordoñez24, Carmen González Montagut25, Andrea García-Valle26, Juan Ramón De Dios27, María Martín López28, Tomás Vázquez Rodríguez29, Delia Fernández-Lozano30, Ignacio Brana Abascal31, Rafael Benito Melero-Gonzalez32, Emilio Giner33, Virginia Ruiz-Esquide34, Clara Ventin Rodriguez35, Marina Rodriguez36, Pablo Andújar-Brazal37, Julia Fernandez Melon23, Lilian M. López-Núñez38, JOSE RAMON LAMUA RIAZUELO39, Anna Pamies Corts40, Carlos Fernández Díaz41, Javier Loricera42, Diego Ferrer43 and Ricardo Blanco-Alonso44, 1Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, 3Rheumatology Division, Bisadoa Hospital, Bidasoa, Spain, 4Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 5Ramón y Cajal University Hospital, Madrid, Madrid, Spain, 6Basurto University Hospital, Bilbao, Spain, 7Hospital Universitario de la Princesa, Madrid, Spain, 8Hospital Reina Sofía, Cordoba, Andalucia, Spain, 9IBIMA, Málaga, Andalucia, Spain, 10Hospital Galdakao- Usansolo, Galdakao, Spain, 11Hospital Universitario San Agustín, Avilés, Spain, 12Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain, 13Complejo Asistencial Universitario de León, Leon, Spain, 14Hospital Universitario de Jaén, Jaén, Spain, 15Hospital Universitario de Gran Canaria Dr. Negrín, Gran Canaria, Spain, 16CAZA, Salamanca, Spain, 17Hospital Germans Trias i Pujol, Badalona, Spain, 18Hospital Severo Ochoa, Madrid, Madrid, Spain, 19H. Universitario La Paz, Madrid, Spain, 20Hospital Universitario de Donosti, Donosti, Spain, 21Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, 22Hospital de Sagunto, Valencia, Spain, 23Hospital Son Espases, Palma, Spain, 24Hospital Universitario Arnau de Vilanova de Lleida, Lleida, Spain, 25Hospital Universitario de Valladolid, Valladolid, Spain, 26Hospital General Río Carrión, Palencia, Spain, 27Osakidetza, Vitoria, Spain, 28General University Hospital of Ciudad Real, Ciudad de México, Spain, 29Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain, 30Hospital Clínico Universitario de Valencia, Valencia, Spain, 31Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain, 32CHU Ourense, O Carballino, Spain, 33Hospital Royo Villanova, Teruel, Spain, 34Hospital Clinic de Barcelona, Barcelona, Spain, 35Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain, 36Hospital Clínico Universitario de Santiago, La Coruna, Spain, 37Hospital Universitario Doctor Peset, Valencia, Spain, 38Hospital Universitari Son Llàtzer, Palma, Spain, 39Hospital Universitario del Henares, Madrid, Spain, 40Hospital Verge de la Cinta, Tortosa, TARRAGONA, Spain, 41Hospital Universitario Santa Lucía, Cartagena, Spain, 42Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 43Division of Pneumology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 44Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Interstitial lung disease (ILD) is a severe complication of rheumatoid arthritis (RA). Abatacept (ABA) has demonstrated efficacy in the treatment of RA-ILD. Our objective…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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