ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 0384 • ACR Convergence 2023

    Targeting NET Formation in Early RA Patients; A Spin-off Study from the NORD-STAR

    Bas Dijkshoorn1, Ting Wang2, Gerdur Maria Grondal3, Daisy Vedder4, Anna Rudin5, Dan Nordstrom6, Bjorn Gudbjornsson7, Kristina Lend8, Till Uhlig9, Espen Haavardsholm9, Merete L Hetland10, Marte Schrumpf Heiberg11, Mikkel Østergaard12, Kim Horslev-Petersen13, John Lampa14, Ronald van Vollenhoven15, Christian Lood2 and Michael Nurmohamed16, 1Amsterdam Rheumatology and Immunology Center, Location Reade, Amsterdam, Netherlands, 2University of Washington, Seattle, WA, 3Department for Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, 4Reade, Amsterdam, Netherlands, 5Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 6Helsinki University Hospital, Helsinki, Finland, 7Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 8Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 9Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 10Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, 11Diakonhjemmet Hospital, Oslo, Norway, 12Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 13Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, 14Stockholm County, Hãsselby, Sweden, 15Amsterdam University Medical Centers, Amsterdam, Netherlands, 16Amsterdam University Medical Centers, Kortenhoef, Netherlands

    Background/Purpose: The formation of neutrophil extracellular traps (NETs) with extrusion of nuclear, granular and cytosolic components from a dying neutrophil, has been described extensively in…
  • Abstract Number: 0400 • ACR Convergence 2023

    Thresholds of Presenteeism Measurement Instruments for Unacceptable Work Participation and Future Adverse Work Outcomes in Rheumatoid Arthritis

    Dafne Capelusnik1, Sofia Ramiro2, Elena Nikiphorou3, Walter P. Maksymowych4, Marina Nighat Magrey5, Helena Marzo-Ortega6 and Annelies Boonen7, 1Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3King's College London, London, United Kingdom, 4University of Alberta, Edmonton, AB, Canada, 5Case Western Reserve University, University Hospitals, Cleveland, OH, 6NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 7Care and Public Health Research Institute (Caphri), Maastricht University, Maastricht, Netherlands

    Background/Purpose: Presenteeism is associated with lower work satisfaction and increased risk of future sick leave in rheumatic diseases. It is generally measured on a continuous…
  • Abstract Number: 0417 • ACR Convergence 2023

    The Role of Rheumatoid Arthritis Flare in the Risk of Alzheimer’s Disease and Related Dementias: A Population-based Cohort Study

    Chanakya Kodishala1, Tina Gunderson2, Edward Lovering2, Rakesh Kumar2, Cynthia Crowson2, John Davis2 and Elena Myasoedova2, 1Mayo Clinic Rochester Minnesota, Rochester, MN, 2Mayo Clinic, Rochester, MN

    Background/Purpose: Patients with rheumatoid arthritis (RA) have increased risk for Alzheimer's disease and related dementias (AD/ADRD). Recent studies have reported an association between RA disease…
  • Abstract Number: 0434 • ACR Convergence 2023

    Effects of B/tsDMARDs on Non-inflammatory Pain in Patients with Rheumatoid Arthritis -ANSWER Longitudinal Cohort Study-

    Mai Yamashita1, Takaichi Okano1, Iku Shirasugi1, Hirotaka Yamada1, Keisuke Nishimura1, Sho Sendo1, Yo Ueda1, Toshihisa Maeda2, Shinya Hayashi2, Wataru Yamamoto3, Akira Onishi4, Kosaku Murakami5, Hideyuki Shiba6, Kenichiro Hata6, Kohei Tsujimoto7, Kosuke Ebina8, Yonsu Son9, Naofumi Yoshida9, Ryota Hara10, Ryu Watanabe11, Motomu Hashimoto11, Ryosuke Kuroda2 and Jun Saegusa1, 1Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, 2Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan, 3Department of Health Information Management, Kurashiki Sweet Hospital, Kurashiki, Japan, 4Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 6Department of Internal Medicine (Ⅳ), Osaka Medical and Pharmaceutical University, Takatsuki, Japan, 7Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Toyonaka, Osaka, Japan, 8Department of Musculoskeletal Regenerative Medicine, Osaka University, Graduate School of Medicine, Toyonaka,Osaka, Japan, 9First Department of Internal Medicine, Kansai Medical University, Osaka, Hirakata, Japan, 10Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan, 11Department of Clinical Immunology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan

    Background/Purpose: Non-inflammatory pain (NIP) is one of the remaining issues in rheumatoid arthritis (RA), and some previous studies suggest that 10-20% of patients with RA…
  • Abstract Number: 0451 • ACR Convergence 2023

    Long-term Clinical Profile of Filgotinib in Patients with Rheumatoid Arthritis by Cardiovascular Risk Factors: A Post Hoc Subgroup Analysis

    Maya Buch1, Jose A Gomez-Puerta2, Gerd Burmester3, Bernard G. Combe4, Vijay Rajendran5, Pieter-Jan Stiers6, Paul Van Hoek7, Katrien Van Beneden7, Jacques-Eric Gottenberg8, Yoshiya Tanaka9, Daniel Aletaha10, René Westhovens11 and Roberto F. Caporali12, 1University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom, 2Department of Rheumatology, Hospital Clinic of Barcelona, Barcelona, Spain, 3Charité – Universitätsmedizin Berlin, Department of Rheumatology and Clinical Immunology, Berlin, Germany, 4Department of Rheumatology, Montpellier University, Montpellier, France, 5Clinical Research, Galapagos NV, Mechelen, Belgium, 6Biostatistics, Galapagos NV, Mechelen, Belgium, 7Medical Safety, Galapagos NV, Mechelen, Belgium, 8Rheumatology Department, Strasbourg University Hospital, Strasbourg, France, 9University of Occupational and Environmental Health, Kitakyushu, Japan, 10Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, Wien, Austria, 11Department of Rheumatology, KU Leuven, Skeletal Biology and Engineering Research Center, Leuven, Belgium, 12Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milano, Italy

    Background/Purpose: Filgotinib (FIL) is an oral Janus kinase 1 preferential inhibitor for the treatment of moderate to severe active RA. A previous pooled analysis reported…
  • Abstract Number: 0636 • ACR Convergence 2023

    Chasing Pain: Investigating Somatosensory Profiles in Patients with Rheumatological Diseases Using Quantitative Sensory Testing

    Claus Juergen Bauer1, Ruth Sophie Schrapper2, Simon Petzinna3, Charlotte Behning4, Tim T.A. Bender5, Peter Brossart1, Martin Muecke6 and Valentin Sebastian Schäfer1, 1Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, 2University of Bonn, Bonn, Germany, 3Clinic of Internal Medicine III, Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital Bonn, Bonn, Germany, 4Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany, 5University Hospital of Bonn, Bonn, Germany, 6Universital Hospital of Aachen, Aachen, Germany

    Background/Purpose: Pain is a prominent symptom in numerous rheumatological diseases. In order to allow for a standardized quantification and the assessment of nociceptive and non-nociceptive…
  • Abstract Number: 0793 • ACR Convergence 2023

    The Dual Specificity Phosphatase 6 (DUSP6) Regulates Arthritis Severity and IL10 Production

    Teresina Laragione, Carolyn Harris, Natasha Rice and Percio Gulko, Icahn school of Medicine at Mount Sinai, New York, NY

    Background/Purpose: We have previously identified the Huntingtin-interacting protein-1 (HIP1) as a new gene implicated in the regulation of the rheumatoid arthritis (RA) fibroblast-like synoviocyte (FLS)…
  • Abstract Number: 0838 • ACR Convergence 2023

    Infusion of Etanercept into the Peripheral Lymphatics Significantly Reduces Disease Activity in Rheumatoid Arthritis Patients with Inadequate Response to Subcutaneous Injections

    Russell Ross1, Vibeke Strand2, Roel Querubin3, John Goldman4, Richard Leff5, Alexis Melson1, Pei-Ling Roerig6 and Alan Smith7, 1Sorrento Therapeutics, Atlanta, GA, 2Stanford University, Portola Valley, CA, 3Marietta Rheumatology Associates, Marietta, GA, 4Northside Hospital, Atlanta, GA, 5Kezar Life Sciences, Chadds Ford, PA, 64P Therapeutics, Orlando, FL, 74P Therapeutics, Atlanta, GA

    Background/Purpose: The lymphatic system serves as a conduit for transporting immune cells and inflammatory molecules present in arthritic joints to lymph nodes (LN), playing a…
  • Abstract Number: 0986 • ACR Convergence 2023

    Medication Use Patterns and Factors Associated with Abnormal Pregnancy Outcomes in Patients with Rheumatoid Arthritis in Korea

    Yeo-Jin Song1, Soo-Kyung Cho1, Yu-Seon Jung2, Jihyun Keum3, Sun-Young Jung2, Dae Hyun Yoo4 and Yoon-Kyoung Sung1, 1Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2College of Pharmacy, Chung-Ang University, Seoul, South Korea, 3Department of Obstetrics and Gynecology, College of Medicine, Hanyang University, Seoul, South Korea, 4Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose: As female patients constitute a significant proportion of rheumatoid arthritis (RA) cases, pregnancy management is crucial for women with RA. This study aimed to…
  • Abstract Number: 1048 • ACR Convergence 2023

    The Prediction of Response to Advanced Therapies on a Joint Level in Rheumatoid Arthritis: The Interpretation of Tenderness and Doppler Ultrasound

    Seyyid Bilal Acikgoz1, Ummugulsum Gazel2, Ricardo Sabido-Sauri2, Ozun Bayindir Tsechelidis3, Amin Zahrai4, Catherine Ivory4, Elliot Hepworth2 and sibel aydin5, 1University of Ottawa, Rheumatology, Ottawa, ON, Canada, 2University of Ottawa, Ottawa, ON, Canada, 3Ottawa University, Ottawa, ON, Canada, 4The Ottawa Hospital Research Institute, Ottawa, ON, Canada, 5University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: Ultrasound (US) has emerged as a sensitive method, especially when compared to clinical examination, for evaluating disease activity in Rheumatoid Arthritis (RA). Several studies…
  • Abstract Number: 1268 • ACR Convergence 2023

    Clinical Characteristics of Patients with Rheumatoid Arthritis (RA) Who Rate Their Global Assessment of Disease Activity Substantially Lower Than Their Physicians (Negative Discordance) Based on a Large RA Database in Japan: A Rare but Important Subgroup

    Tetsuji Sawada1, Susumu Nishiyama2, Shohei Yamashita3, Toshihiro Matsui4 and Shigeto Tohma5, 1Tokyo Medical University Hospital, Shinjuku Tokyo, Japan, 2Kurashiki Medical Center, Kurashiki, Japan, 3Tokyo Medical University Hospital, Shinjuku, Japan, 4NHO Sagamihara National Hospital, Kanagawa, Japan, 5NHO Tokyo National Hospital, Dallas, TX

    Background/Purpose: Discordance between patient global assessment (PGA) and physician global assessment (PhGA) regarding the disease activity of rheumatoid arthritis (RA) can be divided into three…
  • Abstract Number: 1284 • ACR Convergence 2023

    Baseline Data’s Role in Predicting All-cause Mortality in Chinese Rheumatoid Arthritis Patients: Findings from the China Registry of Rheumatoid Arthritis (CREDIT) Study

    Kangping Huang1, Mucong Li1, Chen Yu1, Nan Jiang1, Jiuliang zhao1, Qian Wang1, Peng Yin2, Xinping Tian1, Mengtao Li1 and Xiaofeng Zeng1, 1Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 2Chinese Center for Disease Control and Prevention, Beijing, China

    Background/Purpose: Rheumatoid arthritis (RA) poses significant challenges for patients in China due to prolonged disease duration prior to a definitive diagnosis, resulting in comorbidities and…
  • Abstract Number: 1300 • ACR Convergence 2023

    Bone Marrow Edema in MRI Is More Associated with Rapid Radiographic Progression Than Clinically Relevant Radiographic Progression

    Kou Katayama1, Takanobu Okubo2, Toshikazu Sato1, Kitaru Tanaka3, Tomoki Kawahata3, Yuichi Makino4 and Hiroshi Ito5, 1Department of Orthopedic Surgery, Katayama Orthopedic Rheumatology Clinic, Asahikawa, Japan, 2Department of Radiology, Katayama Orthopedic Rheumatology Clinic, Asahikawa, Japan, 3Division of Metabolism and Biosystemic Science, Gastroenterology, and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan, 4Department of Medicine, Division of Rheumatology, Asahikawa Medical University Hospital, Asahikawa, Japan, 5Department of orthpedic surgery, Asahikawa Medical University, Asahikawa, Japan

    Background/Purpose: Rapid radiographic progression (RRP) is selected as one of the risk factors for difficult- to- treat RA, which needs to be resolved as soon…
  • Abstract Number: 1316 • ACR Convergence 2023

    Influence of Rheumatoid Factor on Serum Drug Levels of TNF Inhibitors with Different Structures in Rheumatoid Arthritis

    Ana Martinez Feito1, Chamaida Plasencia-Rodríguez2, Marta Novella-Navarro2, Johanna E. Gehin3, Borja Hernandez-Breijo4, Claudia M.Brenis5, Alejandro Villalba6, Elisa Fernandez-Fernandez4, Irene Monjo7, Dora Pascual-Salcedo8, Pilar Nozal9 and Alejandro Balsa2, 1Immuno-Rheumatology research group , Institute for Health Research (IdiPAZ), Madrid, Spain, 2Hospital Universitario La Paz, Madrid, Spain, 3Dept. of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, 4La Paz University Hospital, Madrid, Spain, 5VIB-UGent Inflammation Research Center Gent, Belgium, Gent, Belgium, 6Rheumatology Department, La Paz University Hospital, Madrid, Spain, 7University Hospital La Paz, Madrid, Spain, 8Immuno-Rheumatology Research Group, La Paz University Hospital, Madrid, Spain, 9Immunology Unit in La Paz University Hospital-Idipaz, Madrid, Spain

    Background/Purpose: Elevated rheumatoid factor (RF) in patients with rheumatoid arthritis (RA) is associated with higher disease activity. A significantly lower efficacy of TNF inhibitors (TNFi)…
  • Abstract Number: 1333 • ACR Convergence 2023

    Rheumatoid Arthritis-associated Lymphoproliferative Disorders: A Multi-center Analysis of Clinical Outcomes and Evaluation of Anti-rheumatic Drugs After LPD Onset

    YOSHIHIKO HOSHIDA1, Atsuko Tsujii2, SHIRO OHSHIMA3, YUKIHIKO SAEKI3, MASATO YAGITA4, TOMOYA MIYAMURA5, Masao Katayama6, TOMONORI KAWASAKI7, YASUSHI HIRAMATSU8, Hisaji Oshima9, TOSHIHIKO MURAYAMA10, SHINJI HIGA11, KAZUYA KURAOKA12, FUMINORI HIRANO13, KENJI ICHIKAWA14, MITSUTOSHI KUROSAWA15, HIROAKI SUZUKI15, NORIYUKI CHIBA16, TAKAO SUGIYAMA17, YUKO MINAMI18, HITOSHI NIINO19, ATSUSHI IHATA20, IKUO SAITO21, AKIKO MITSUO22, TOSHITAKA MAEJIMA23, ATSUHIRO KAWASHIMA24, HIROSHI TSUTANI25, KOICHIRO TAKAHI26, TAKAHIKO KASAI27, YOKO SHINNO28, YOSHIRO TACHIYAMA29, NORIHIRO TERAMOTO30, KENICHI TAGUCHI31, SHINJI NAITO32, SHIGERU YOSHIZAWA33, MASAHIRO ITO34, YASUO SUENAGA35, Shunsuke Mori36, SHOICHI NAGAKURA37, NORIE YOSHIKAWA38, MITSUHARU NOMOTO39, ATSUHISA UEDA40, SHOUHEI NAGAOKA41, YUKIO TSUURA42, KEIGO SETOGUCHI43, SHOJI SUGII44, Asami Abe45, TOSHIAKI SUGAYA46, HIROYUKI SUGAHARA47, MASAHIRO KOSETO48, YASUO KUNUGIZA2, NORISHIGE IIZUKA3, RYOSUKE YOSHIHARA4, HIROKI YABE5, TOMOAKI FUJISAKI6, EIICHI MORII7, MORISHIGE TAKESHITA8, MASAKAZU SATO9, KAZUYOSHI SAITO10, Kiyoshi Matsui11, YASUHIKO TOMITA12, HIROSHI FURUKAWA13 and Shigeto Tohma14, 1National Hospital Organization Osaka Minami Medical Center, Kawachinagano, Japan, 2Osaka Minami Medical Center, Kawachinagano City, Japan, 3National Hospital Organization (NHO), Osaka Minami Medical Center, Kawachinagano, Japan, 4Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-kofukai, Osaka, Japan, 5NHO Kyushu Medical Center, Fukuoka, Japan, 6National Hospital Organization, Nagoya Medical Center, Nagoya, JP, Nagoya, Japan, 7NHO Nagoya Medical Center, Nagoya, Japan, 8Japanese Red Cross Society Himeji Hospital, Himeji, Japan, 9National Tokyo Medical Center, Tokyo, Japan, 10NHO Kumamoto Medical Center, Kumamoto, Japan, 11Daini Osaka Police Hospital, Osaka, Japan, 12NHO Kure Medical Center /Chugoku Cancer Center, Kure, Japan, 13NHO Asahikawa Medical Center, Asahikawa, Japan, 14Nissei hospital, Sapporo, Japan, 15NHO Hokkaido Cancer Center, Sapporo, Japan, 16NHO Morioka Medical Center, Morioka, Japan, 17NHO Shimoshizu Hospital, Yotsukaido, Japan, 18NHO Ibarakihigashi Hospital, Ibaraki, Japan, 19NHO Yokohama Medical Center, Yokohama, Japan, 20National Hospital Organization Yokohama Medical Center, Yokohama, Japan, 21NHO Sagamihara Hospital, Sagamihara, Japan, 22NHO Disaster Medical Center, Tachikawa, Japan, 23NHO Shinshu Ueda Medical Center, Ueda, Japan, 24NHO Kanazawa Medical Center, Kanazawa, Japan, 25NHO Awara Hospital, Awara, Japan, 26NHO Osaka Toneyama Medical Center, Toyonaka, Japan, 27Japan Red Cross Society Tokushima Hospital, Komatsushima, Japan, 28NHO Okayama Medical Center, Okayama, Japan, 29NHO Hiroshima Nishi Medical Center, Otake, Japan, 30NHO Shikoku Cancer Center, Matsuyama, Japan, 31NHO Kyushu Cancer Center, Fukuoka, Japan, 32NHO Ureshino Medical Center, Ureshino, Japan, 33NHO Fukuoka Hospital, Fukuoka, Japan, 34NHO Nagasaki Medical Center, Omura, Japan, 35NHO Beppu Medical Center, Beppu, Japan, 36NHO Kumamoto Saishun Medical Center, Koshi, Japan, 37NHO Kumamoto Minami Hospital, Uki, Japan, 38NHO Miyakonojo Medical Center, Miyakonojo, Japan, 39NHO Kagoshima Medical Center, Kagoshima, Japan, 40Yokohama City University Medical Center, Yokohama, Japan, 41Yokohama Minami Kyosai Hospital, Yokohama, Japan, 42Department of Pathology Yokosuka Kyosai Hospital, Yokosuka, Japan, 43Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital / Tokyo Metropolitan Komagome Hospital, Tokyo, Japan, 44Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan, 45Niigata Rheumatic Center, Shibata, Japan, 46Fuchu Hospital, Izumi, Japan, 47Sumitomo Hospital, Osaka, Japan, 48Nippon Life Hospital, Osaka, Japan, 49JCHO Hoshigaoka Medical Center, Hirakata, Japan, 50Kishiwada City Hospital, Kishiwada, Japan, 51Hyogo Prefectural Kakogawa Hospital, Kakogawa, Japan, 52Ako Central Hospital, Ako, Japan, 53Matsuyama Red Cross Hospital, Matsuyama, Japan, 54Osaka University, Suita, Japan, 55Fukuoka University, Fukuoka, Japan, 56Kurashiki University of Science and the Arts, Kurashiki, Japan, 57University of Occupational and Environmental Health, Kitakyushu, Japan, 58Hyogo Medical University, Nishinomiya, Japan, 59International University of Health and Welfare, Otawara City, Japan, 60NHO Tokyo National Hospital, Kiyose, Japan, 61NHO Tokyo National Hospital, Dallas, TX

    Background/Purpose: The largest multi-center collaborative study on lymphoproliferative disorders (LPD) in rheumatoid arthritis (RA) (RA-LPD) in Japan was conducted to characterize its clinical outcomes and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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