ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 2223 • ACR Convergence 2024

    Validation Study in Early Rheumatoid Arthritis Patients of the Spanish Society of Rheumatology (SER)/Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) Screening Criteria for Interstitial Lung Disease

    Martí Aguilar Coll1, Javier Narvaez-García2, Monserrat Roig Kim2, Pol Maymó3, Judith Palacios1 and Joan Miquel Nolla1, 1Bellvitge University Hospital, L'Hospitalet de Llobregat, Catalonia, Spain, 2Hospital Universitario de Bellvitge, Barcelona, Spain, 3Hospital Universitario de Bellvitge., Barcelona, Spain

    Background/Purpose: A multidisciplinary proposal of screening criteria for interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) was published in 2023 [Narváez J et…
  • Abstract Number: 2239 • ACR Convergence 2024

    Age, Seropositivity and Inflammation Determine Risk versus Benefit of Endogenous Estrogens on Coronary Atherosclerosis in Rheumatoid Arthritis

    George Karpouzas1, Bianca Papotti2, Sarah Ormseth3, Marcella Palumbo2, Elizabeth Hernandez3, Matthew Budoff4 and Nicoletta Ronda2, 1Harbor-UCLA Medical Center, Torrance, CA, 2University of Parma, Parma, Italy, 3The Lundquist Institute, Torrance, CA, 4Harbor-UCLA Medical Center and the Lundquist Institute for Biomedical Innovation, Torrance, CA

    Background/Purpose: Endogenous estrogens (E) appear cardioprotective in women in the general population. Yet, proinflammatory effects were described in chronic autoimmune diseases depending on stage, cell-type…
  • Abstract Number: 2259 • ACR Convergence 2024

    Effects of Anti-Obesity Medications in RA Patients

    Elizabeth Dente1, David Kellner2, Vincent Tran2, Travis Welsh2, Victor Tran3, Angshuman Saha1, Jenny Brook1, David Elashoff4 and Veena Ranganath2, 1UCLA, Los Angeles, 2UCLA, Los Angeles, CA, 3UCLA, Costa Mesa, CA, 4UCLA Department of Medicine Statistics Core, Los Angeles

    Background/Purpose: It is standard practice to advocate for weight loss in patients with rheumatoid arthritis (RA) and obesity. Obesity and rheumatoid arthritis are both independently…
  • Abstract Number: 2277 • ACR Convergence 2024

    Switching to a Targeted Drug with a Different Mode of Action After Discontinuation of the First TNF Inhibitor Is Associated with Better Drug Survival Compared to a Second TNF Inhibitor in Rheumatoid Arthritis: A Propensity Score-matched Analysis from the Czech ATTRA Registry

    Herman Mann1, Jana Baranová2, Pavel Horak3, Karel Pavelka4, Ladislav Šenolt5, Jiří Vencovský5, Kateřina Kusalová2 and Jakub Závada4, and ATTRA registry, 1Revmatologický ústav, Praha, Czech Republic, 2Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic, 33rd Department of Internal Medicine - Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc & Palacky University Olomouc, Faculty of Medicine and Dentistry, Olomouc, Olomoucky kraj, Czech Republic, 4Institute of Rheumatology and Charles University, Praha, Czech Republic, 5Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic

    Background/Purpose: TNF inhibitors (TNFi) are currently the most commonly used first-line targeted therapy for patients with rheumatoid arthritis (RA). After discontinuation of the first TNFi,…
  • Abstract Number: 2540 • ACR Convergence 2024

    Characterizing the Functional Role of Type I Interferons in Inflammatory Arthritis

    Mary Huang, Richard Bell, Toolika Singh and Lionel Ivashkiv, Hospital for Special Surgery, New York, NY

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation due to cellular infiltration and inflammatory mediators. Type I interferons (IFN) have…
  • Abstract Number: 2656 • ACR Convergence 2024

    Short-Term Effectiveness of a Walk with Ease Program Delivered by Telephone on Arthritis-Related Symptoms, Function, and Physical Activity

    Christine Pellegrini, Sara Wilcox, Yesil Kim, Katherine Devivo, Scott Jamieson, Kailyn Horn and Daniel Heidtke, University of South Carolina, Columbia, SC

    Background/Purpose: Walk With Ease (WWE) is a 6-week arthritis-appropriate evidence-based physical activity program traditionally offered in a face-to-face format. However, as many populations encounter participation…
  • Abstract Number: 0041 • ACR Convergence 2024

    Disease Activity and Serological Inflammatory Markers Are Associated with TNF-a and IL-6-Induced Osteoclasts, but Not with RANKL-Induced Osteoclasts in Peripheral Blood Monocytes from Patients with Rheumatoid Arthritis

    Yokota Kazuhiro1, Yoshimi Aizaki1, Miyoko Sekikawa2, Hiroshi Kajiyama1, Yasuto Araki1, Yuho Kadono2, Yuji Akiyama1 and Toshihide Mimura1, 1Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, Iruma-gun, Saitama, Japan, 2Department of Orthopaedic Surgery, Saitama Medical University, Saitama, Japan, Iruma-gun, Saitama, Japan

    Background/Purpose: We previously reported that a combination of TNF-α and IL-6 induces mouse osteoclast (OC)-like cells and human OCs with bone resorption activity [Arthritis &…
  • Abstract Number: 0058 • ACR Convergence 2024

    Bradykinin Receptor B1 Blockade Suppresses Soluble CD13-Induced Differentiation of Osteoclasts from Monocytes

    Sei Muraoka1, Qi Wu2, Mikel Gurrea-Rubio3, Camila Amarista2, William Brodie2, Megan Mattichak2, Yuzo Ikari4, Caroline Foster2, Phillip Campbell2, David Fox5 and Pei-Suen Tsou2, 1University of Michigan, Toyko, Japan, 2University of Michigan, Ann Arbor, MI, 3University of Michigan - Ann Arbor, Ann Arbor, MI, 4Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 5University of Michigan, Dexter, MI

    Background/Purpose: CD13 is an ectopeptidase expressed on myeloid cells, endothelial cells, and rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS). Soluble (s) CD13 is generated by matrix…
  • Abstract Number: 0143 • ACR Convergence 2024

    Behavioral Factors and Chronic Conditions Associated with Rheumatoid Arthritis, KNHANES 2010 to 2021

    GI HYUN MYUNG and Juwon Lim, Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: Rheumatoid arthritis (RA) is associated with multiple genetic and environmental factors. In terms of environmental, dietary and lifestyle factors, there have been discrepancies on…
  • Abstract Number: 0226 • ACR Convergence 2024

    Global Ultrasound Scoring Systems for Assessing Synovitis in Rheumatoid Arthritis

    Peter Mandl1, Clara Watschinger1, Enrico De Lorenzis2, Brigitte Wildner3, Lene Terslev4, Irina Gessl1, Helen Keen5, Carlos Pineda6 and Maria-Antonietta D'Agostino7, and OMERACT Ultrasound Working Group, 1Department of Rheumatology, Medical University of Vienna, vienna, Austria, 2Catholic University of the Sacred Heart, Roma, Rome, Italy, 3Central Library, Medical University of Vienna, Vienna, Austria, 4Rigshospitalet-Glostrup & COPECARE, Glostrup, Denmark, 5University of Western Australia, Daglish, Western Australia, Australia, 6Instituto Nacional de Rehabilitacion, Mexico City, Mexico, 7Department of Rheumatology, Universita Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Rome, Italy, Rome, Italy

    Background/Purpose: Musculoskeletal ultrasound (MSUS) is widely regarded as a valuable tool for assessing the full extent of synovitis in patients with rheumatoid arthritis (RA). In…
  • Abstract Number: 0367 • ACR Convergence 2024

    Opinions from Rheumatoid Arthritis Patients and Providers on Discontinuing Methotrexate in Stable Disease

    Peri Newman1, Sharon Banks1, Rayford June2, Erik Lehman3, Glennys Smith4, Vandana Rai4, Nicole Wilson4, Nancy Olsen5 and Tarun Sharma4, 1Penn State Health, Hershey, PA, 2Penn State College of Medicine/Lebanon VA Medical Center, Hummelstown, PA, 3Penn State College of Medicine, Hershey, PA, 4Allegheny Health Network, Pittsburgh, PA, 5Penn State University/Milton S Hershey, Hershey, PA

    Background/Purpose: The 2021 American College of Rheumatology guidelines for treatment of rheumatoid arthritis (RA) conditionally recommend a gradual discontinuation of methotrexate (MTX) over biologic discontinuation.…
  • Abstract Number: 0462 • ACR Convergence 2024

    Circulating Mediators of Endothelial Dysfunction as Predictors of Incident Heart Failure in Rheumatoid Arthritis

    Tate Johnson1, Michael Duryee1, Carlos Hunter1, Punyasha Roul2, Joshua Baker3, grant Cannon4, Beth Wallace5, Paul Monach6, Andreas Reimold7, Gail Kerr8, Isaac Smith9, John Richards10, Katherine Wysham11, Gary Kunkel12, Iris Lee13, Daniel Anderson14, Geoffrey Thiele1, Ted Mikuls1 and Bryant England1, 1University of Nebraska Medical Center, Omaha, NE, 2UNMC, Omaha, NE, 3University of Pennsylvania, Philadelphia, PA, 4University of Utah and Salt Lake City VA, Salt Lake City, UT, 5Michigan Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, 6VA Boston Healthcare System, Boston, MA, 7Dallas VA Medical Center, Dallas, TX, 8Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, 9Duke University Hospital, Durham, NC, 10Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, 11VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 12University of Utah and George E Wahlen VAMC, Salt Lake City, UT, 13Washington University in St Louis, Saint Louis, MO, 14University of Nebraska Medical Center, Durham, NC

    Background/Purpose: Endothelial dysfunction, leading to myocardial inflammation and dysfunction, may drive a heightened risk of heart failure (HF) in people with rheumatoid arthritis (RA). Circulating…
  • Abstract Number: 0478 • ACR Convergence 2024

    Skin Sodium in Patients with Rheumatoid Arthritis: Association with Blood Pressure and Disease Activity

    Carolina Ramirez, Annette Oeser, Rachelle Crescenzi, C. Michael Stein and Michelle Ormseth, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Sodium is stored in tissues such as the skin where it may contribute to development and progression of autoimmune diseases and hypertension through activation…
  • Abstract Number: 0496 • ACR Convergence 2024

    Dissecting Early RA Patient Trajectories Through Time-independent Disease State Identification Identifies Distinct Patterns Dissected by Inflammation in Blood or Joints

    Nils Steinz1, Tjardo Maarseveen2, Andrew Cope3, John Isaacs4, Aaron Winkler5, Thomas Huizinga6, Yann Abraham7 and Rachel Knevel1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Leiden University Medical Center, Wormerveer, Netherlands, 3King's College London, London, United Kingdom, 4Translational and Clinical Research Institute, NIHR Newcastle Biomedical Research Centre, Newcastle University and The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom, 5Pfizer Inc., Cambridge, MA, 6Department of Rheumatology, Leiden University, Leiden, Netherlands, 7Janssen Research and Development, Beerse, Belgium

    Background/Purpose: Patients with RA display different trajectories in the improvement of disease activity. Discerning the RA trajectories, how they differ between patients and which factors…
  • Abstract Number: 0512 • ACR Convergence 2024

    Co-stimulatory Blockade Causes Targeted Quantitative and Clonotypic Contractions in Extrafollicular B-cell Subsets in Seropositive RA Patients

    Jasmine Shwetar1, William Rigby2, Sladjana Skopelia-Gardner3, Abhimanyu Armarnani1, Kelly Ruggles1 and Gregg Silverman1, 1NYU Grossman School of Medicine, New York, NY, 2Dartmouth-Hitchcock, Norwich, VT, 3Dartmouth Hitchcock Medical Center, Hanover, NH

    Background/Purpose: Of all approved biologic therapies, other than anti-CD20 depletion only CTLA4-Ig/abatacept treatment reduces levels of pathologic autoantibodies. Herein, our primary goal has been to…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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