ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 1395 • ACR Convergence 2024

    Effects of Butyrate Supplementation in Modulation of Gut Microbiome and Its Metabolites in New Onset Rheumatoid Arthritis

    Rebecca Blank1, Alba Boix-Amoros2, Erin Reilly3, Kevin Bu4, Ian Cunningham5, Renuka Nayak6, Andrew Patterson7, Jose Clemente4 and Jose Scher8, 1NYU, New York, NY, 2Icahn School of Medicine, New York, NY, 3Penn State, State Park, PA, 4Icahn School of Medicine at Mount Sinai, New York, NY, 5NYU Langone Health, New York, NY, 6University of California, San Francisco (UCSF), San Francisco, CA, 7Penn State University, State College, PA, 8New York University School of Medicine, New York, NY

    Background/Purpose: The gut microbiome and its metabolites are dysregulated in RA and other immune-mediated inflammatory diseases. However, the significance of this observation and its implications…
  • Abstract Number: 1664 • ACR Convergence 2024

    Identification of Spatial Determinants of Treatment Response in Rheumatoid Arthritis Synovia

    ilya Korsunsky1, Roopa Madhu2, Kevin Wei3, Kartik Bhamidipati1, Miles Tran1, Sonia Presti1, Anna Helena Jonsson4, Ellen Gravallese5, Michael Brenner6, Soumya Raychaudhuri1, Jennifer Seifert7, Costantino Pitzalis8, Fan Zhang9, Larry Moreland10, V. Michael Holers10, Michael Clayman11, Myles Lewis12, Ce Gao1, Michael J Zuscik13 and Accelerating Medicines Partnership Autoimmune and Immune-Mediated Disease14, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Brookline, MA, 3Brigham and Women's Hospital at Harvard Medical School, Boston, MA, 4University of Colorado School of Medicine, Aurora, CO, 5Brigham and Women's Hospital, Harvard Medical School, Chestnut Hill, MA, 6Brigham and Women's Hospital, Harvard Medical School, Newton, MA, 7University of Colorado and Oklahoma Medical Research Foundation, Aurora, CO, 8QMUL, Bromley Kent, United Kingdom, 9University of Colorado, Aurora, CO, 10University of Colorado, Denver, CO, 11University of Colorado School of Medicine, Burlington, MA, 12Queen Mary University of London, London, United Kingdom, 13Department of Orthopedic Surgery, University of Colorado School of Medicine, Aurora, CO, 14Multiple Institutions, Oklahoma City

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by immune infiltration of the synovial tissue, resulting in joint damage. In RA, synovia exhibit distinct…
  • Abstract Number: 1746 • ACR Convergence 2024

    Global Recruiting Patterns Are Associated with Placebo Response Rates in Clinical Trials of Rheumatoid Arthritis

    Andreas Kerschbaumer1, Marlene Steiner2, Pascale Pruckner1, Josef Smolen3 and Daniel Aletaha4, 1Medical University of Vienna, Vienna, Wien, Austria, 2Medical University Vienna, Vienna, Wien, Austria, 3Medical University of Vienna, Vienna, Austria, 4Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Wien, Austria

    Background/Purpose: Therapeutic advances of the recent past have led to significant changes in clinical practice when treating patients with rheumatoid arthritis (RA). Since the advent…
  • Abstract Number: 1881 • ACR Convergence 2024

    Cross-State Comparative Assessment of Burden of Rheumatoid Arthritis in the United States and It’s Trend from 1990-2021: A Benchmarking Analysis for the Global Burden of Disease Study 2022

    Rafael Sanchez-Dopazo,1, Eva Kalra2, Shadi Abuhashem3, abobakr Saleh4, Khalid Faris5, Rutvik Raval6, Shamitha Hejmadi6, Lovekumar Vala7, Riya Dhadhal8 and Hardik Desai9, 1Larkin Community Hospital Palm Springs Campus, Hialeah, FL, 2Trident Medical Cente, Charleston, SC, 3Alquds University, Jerusalem, West Bank, Palestine, 9458123, Gaza, Palestinian Territories, 4kasr alainy Medical School - Cairo University,Egypt/ 11956, Cairo, Egypt, 5Studied in Al-Quds university, Palestine, Gaza, Palestinian Territories, 6B.J. Medical College, Ahmedabad, India, 7Department of Internal Medicine, Shantabaa Medical College and General Hospital, Amreli, Gujarat, India, 365601, Amreli, Gujarat, India, 8SMIMER Hospital & Medical College, Surat, Gujarat, India, 9Gujarat Adani Institute of Medical Sciences, Bhuj, India

    Background/Purpose: The burden of Rheumatoid Arthritis (RA) in the United States is considerable, both in terms of its prevalence and the economic costs it incurs.…
  • Abstract Number: 1964 • ACR Convergence 2024

    Comparison of Knee Minimum Joint Space Width Measurements Using Deep Learning in Patients with Rheumatoid Arthritis and Osteoarthritis Undergoing Total Knee Arthroplasty

    Kellen Mulford1, Elizabeth Kaji1, Austin Grove1, Ronnie Sebro2, Cody Wyles1, John Davis1 and Cynthia Crowson1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Jacksonville, FL

    Background/Purpose: While large joint damage is a hallmark of both Osteoarthritis (OA) and Rheumatoid Arthritis (RA), the mechanisms of degradation are substantially different. Minimum joint…
  • Abstract Number: 2209 • ACR Convergence 2024

    Impact of Common Infections on Medication Interruptions, Quality of Life, and Disease Flares in Patients with Rheumatoid Arthritis

    Michael George1, Kelly Gavigan2, Shilpa Venkatachalam3, David Curtis2, Laura Stradford4, William Benjamin Nowell5, Joshua Baker1, Fenglong Xie6 and Jeffrey Curtis7, 1University of Pennsylvania, Philadelphia, PA, 2Global Healthy Living Foundation, Upper Nyack, NY, 3Global Healthy Living Foundation, New York, NY, 4Global Healthy Living Foundation, Nyack, NY, 5Regeneron, New York, NY, 6University of Alabama at Birmingham, Birmingham, AL, 7University of Alabama at Birmingham, Hoover, AL

    Background/Purpose: Serious infections are a major cause of morbidity and mortality in patients with RA, but less is known about more common, non-serious infections. We…
  • Abstract Number: 2227 • ACR Convergence 2024

    Worrisome Mortality Trends over 20 Years Among Patients with Underlying Ischemic Heart Disease and Rheumatoid Arthritis

    Yukthi Mudiam1 and Shreyas Singireddy2, 1Apollo Institute of Medical Sciences and Research, Richmond, TX, 2Department of Cardiology, University of Illinois College of Medicine, Peoria, IL

    Background/Purpose: Ischemic heart disease (IHD) is one of the leading causes of death in the United States. Rheumatoid arthritis (RA), a chronic inflammatory condition affecting…
  • Abstract Number: 2243 • ACR Convergence 2024

    A Cross-sectional Study of the Association Between Anxiety State and Various Factors in Patients with Rheumatoid Arthritis

    Yusuke Miwa1, Yuko Miwa2 and Michio Hosaka3, 1Division of Rheumatology, Department of Medicine, School of Medicine, Showa University, Tokyo, Tokyo, Japan, 2Department of Nursing, Showa University School of Nursing and Rehabilitation Sciences, Setagaya-ku, Tokyo, Japan, 3Department of psychosomatic medicine, Katsuyama Clinic, Kawaguchiko, Yamanashi, Japan

    Background/Purpose: Although the complication of anxiety in rheumatoid arthritis (RA) patients is reported to be 1.2 times higher than in healthy controls and weakly correlated…
  • Abstract Number: 2263 • ACR Convergence 2024

    The Potential Use of Circulating Extracellular Vesicles for Improved Diagnosis and Therapy in Rheumatic Inflammatory/autoimmune Diseases: Proof of Concept Studies

    Gilad Halpert1, Ori Moskovitch2, Linoy Israel2, Eri Govrin2, Boris Gilburd2, Ori Segal2, Adi Anaki3, Tal Caller2, Daniel Yechiali2, Shlomo Segev2, Omer Gendelman4, Abdulla Watad5, Ruty Mehrian-Shai2, Rachella Popovtzer3 and Howard Amital6, 1CAHIM SHEBA MEDICAL CENTER, Tel Hashomer, Israel, 2Sheba Medical Center, Ramat-Gan, Israel, 3Bar Ilan University, Ramat-Gan, Israel, 4Sheba Medical Center, Ramat Gan, Israel, 5Tel Hashomer Medical Center, Ramat Gan, Israel, 6Sheba Medical Center, Tel-Hashomer, Israel, Ramat Gan, Israel

    Background/Purpose: Many patients with rheumatic conditions do not completely respond or are refractory to biological therapy. Therefore, there are unmet medical needs in the treatment…
  • Abstract Number: 2281 • ACR Convergence 2024

    Assessment of Comparative Efficacy Between Candidate Biosimilar AVT05 and Reference Golimumab

    Monica Luque1, Kristina Zhelyazkova1, Laxmikant Vashishta2, Masna Rai3, Abid Sattar4, Richard Bucknall4, Steffen Leutz3 and FAUSTO BERTI1, 1Alvotech, Zürich, Switzerland, 2Alvotech, Bangalore, India, 3Alvotech, Jülich, Germany, 4Alvotech, London, United Kingdom

    Background/Purpose: Golimumab is a safe and effective treatment for RA. Biosimilars to the reference product (RP) may make treatment more accessible. We assessed comparable efficacy…
  • Abstract Number: 2553 • ACR Convergence 2024

    Predictors of Biologic and Targeted Synthetic DMARD Initiation for Rheumatoid Arthritis Across Underserved Patient Groups: Insights from a National Cohort Study

    Mark Russell1, Mark Gibson2, Benjamin Zuckerman1, Kanta Kumar3, Shirish Dubey4, Maryam Adas2, Edward Alveyn2, Samir Patel1, Zijing Yang1, Katie Bechman2, Elizabeth Price5, Sarah Gallagher6, Andrew Cope2, Sam Norton1 and James Galloway7, 1King's College London, London, England, United Kingdom, 2King's College London, London, United Kingdom, 3University of Birmingham, Birmingham, United Kingdom, 4Oxford University Hospitals NHS FT, Oxford, United Kingdom, 5Great Western Hospital NHS Foundation Trust, Swindon, England, United Kingdom, 6British Society for Rheumatology, London, United Kingdom, 7Centre for Rheumatic Diseases, King's College London, London, United Kingdom

    Background/Purpose: Quantifying healthcare inequality is essential to addressing the imbalance in outcomes attributable to age, gender, ethnicity and multimorbidity. In this study, we analysed differences…
  • Abstract Number: 2673 • ACR Convergence 2024

    Changes in Mortality Risk After Stopping Glucocorticosteroids – a Population-based Study in Rheumatoid Arthritis

    Diane Lacaille1, Coraline Danieli2, Kasra Moolooghy1 and Michal Abrahamowicz3, 1Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada, 2Research Institute of McGill University Health Center (RI-MUHC), Montreal, QC, Canada, 3McGill University, Verdun, Canada

    Background/Purpose: Glucocorticosteroid (GC) use is associated with increased mortality risk, especially from cardiovascular diseases (CVD) and infections, with dose and duration of use influencing risk.…
  • Abstract Number: 0044 • ACR Convergence 2024

    Synovial Phosphoproteomic Profiling in Early and Advanced Rheumatoid Arthritis (R4RA Trial) Identifies Specific Signaling Pathways Linked to Distinct Pathotypes

    Cankut Cubuk1, Rachel Lau1, Vinothini Rajeeve2, Pedro Cutillas2, Rebecca Hands1, Liliane Fossati-Jimack1, Anna Surace1, Alessandra Nerviani1, Felice Rivellese1, Myles Lewis3 and Costantino Pitzalis4, and the R4RA Collaborative Group, 1Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London and Barts NIHR BRC & NHS Trust, London, EC1M 6BQ, London, United Kingdom, 2Cell Signalling and Proteomics Group, Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, London, United Kingdom, 3Queen Mary University of London, London, United Kingdom, 4QMUL, Bromley Kent, United Kingdom

    Background/Purpose: Rheumatoid arthritis (RA) is an incurable autoimmune disease where response to therapy is heterogenous. Clinically indistinguishable RA patients can be classified histo-pathologically into three…
  • Abstract Number: 0061 • ACR Convergence 2024

    Comparative Transcriptional Profiling of IPF and RA-ILD Lung Tissue Demonstrates Both Overlapping and Distinct Cell-specific Signaling Pathways

    Joshua Sciurba1, Daniel Kass1, Eleanor Valenzi2, John Sembrat2, Robert Lafyatis3 and Dana Ascherman4, 1University of Pittsburgh School of Medicine, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 4Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA

    Background/Purpose: Transcriptional profiling represents a powerful tool for deciphering disease-relevant pathways and deriving functional biomarkers.  Given the shared demographic, genetic, and clinico-epidemiologic features between rheumatoid…
  • Abstract Number: 0149 • ACR Convergence 2024

    Beliefs on Self-Management in Rheumatoid Arthritis Compared to Other Chronic Diseases Using the Nationally Representative Medical Expenditure Panel Survey

    Samuel Good1, Bryant England2 and Elizabeth Volkmann3, 1University of California, Los Angeles, Los Angeles, CA, 2University of Nebraska Medical Center, Omaha, NE, 3University of California, Department of Medicine, Los Angeles, CA, USA, Los Angeles

    Background/Purpose: Studies that evaluate experiences of living with rheumatoid arthritis (RA) have found that patients identify self-empowerment and a sense of control as important factors…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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