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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 2684 • ACR Convergence 2025

    Multimodal Analysis Revealed Altered Brain Connectivity Patterns and Neuroinflammatory Processes in the Background of Difficult-To-Treat Rheumatoid Arthritis

    Lilla Gunkl-Tóth1, Gergely Orsi2, Noémi Császár-Nagy3, Lili Duzsik4, Gábor Mátay4, Gábor Kumánovics5, Gábor Sütő2, Krisztina Csókási2, Szabolcs Takács6, Zoltán Vidnyánszky7, József Kun2, Krisztina Takács-Lovász2, Gellért Karvaly8, Róbert Farkas8, Anett Pintér8, Panna Királyhidi8, György Nagy8 and Zsuzsanna Helyes2, 1Semmelweis University, Budapest, Budapest, Hungary, 2University of Pécs, Pécs, Hungary, 3National University of Public Services, Budapests, Hungary, 4Psychosomatic Outpatient Clinic, Budapest, Hungary, 5University of Pecs, Pecs, Hungary, 6Károli Gáspár University, Budapest, Hungary, 7Brain Imaging Centre, Research Centre for Natural Sciences, Budapest, Hungary, 8Semmelweis University, Budapest, Hungary

    Background/Purpose: Despite advances in rheumatoid arthritis (RA) treatment, 5–20% of patients experience persistent symptoms, particularly pain, and are classified as difficult-to-treat (D2T). Factors such as…
  • Abstract Number: 2612 • ACR Convergence 2025

    Automated, Artificial Intelligence-supported Sonographic Examination of the Hands for the Detection and Quantification of Arthritis and Osteoarthritis in the Hand and Finger Joints in Outpatient Rheumatology Care

    Oliver Sander1, Lea Ormeloh1, Laura Grünkewitz1, Martin Gallmann1, Benedict Blümel1, Rishi Adhikari1, Hasan Acar1, Gamal Chehab1, Jörg Distler2 and Jutta Richter3, 1Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University., Düsseldorf, Germany, 2University Hospital Duesseldorf and HHU, Duesseldorf, Germany, 3Clinic for Rheumatology and Hiller Research Unit, Heinrich-Heine-University Duesseldorf, Medical Faculty, Duesseldorf, Germany, Düsseldorf, Germany

    Background/Purpose: The integration of artificial intelligence (AI) in combination with robotics into clinical diagnostics has the potential to increase precision and efficiency and relieve increasingly…
  • Abstract Number: 2285 • ACR Convergence 2025

    Synovium-on-a-chip – Development of a Humanized Rheumatoid Arthritis Model that Mimics Disease and Patient Biological Heterogeneity

    Theresa Wampler Muskardin1, Ruiqi Chen2, Yeji Lee3, Azka Ali3, Andrra Nimoni3, Christele Felix3, Hattie Heiland3, Romy Kallas3, Daniel Ramirez4, David Mayman3, Timothy Niewold5 and Weiqiang Chen6, 1Hospital for Special Surgery and Weill Cornell Medicine, New York, NY, 2New York University - Tandon School of Engineering, New York, NY, 3Hospital for Special Surgery, New York, NY, 4Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 5Hospital for Special Surgery, New York, New York, 6New York University, Tandon School of Engineering, New York, NY

    Background/Purpose: In rheumatoid arthritis (RA), reasons for treatment resistance and alternate strategies that would be more effective in treatment-resistant patients remain unknown. Accurate methodology to…
  • Abstract Number: 2267 • ACR Convergence 2025

    Impact of Baseline Cardiovascular Risk Factors Comorbidities on an Adalimumab Biosimilar Efficacy, Quality of Life and Safety In Patients with Patients with Moderately to Severely Active Rheumatoid Arthritis: Results from the AURIEL-RA study

    Chris Edwards1, Janet Pope2, Joelle Monnet3 and Maria Romanova Michailidi4, 1University Hospital Southampton, Southampton, United Kingdom, 2University of Western Ontario, London, ON, Canada, 3Fresenius Kabi SwissBioSim, Eysins, Switzerland, 4University of Geneva, Eysins, Switzerland

    Background/Purpose: RA has been associated with an increase risk of cardiovascular morbidity and mortality1. The present analysis was performed to assess the efficacy (on ACR…
  • Abstract Number: 2251 • ACR Convergence 2025

    Dual Diagnoses, Diminished Survival: Association between rheumatoid arthritis and survival among older adults with lung cancer

    Michelle Nguyen1, Aaron Baraff2, Alexandra Schmidt2, Alexander Peterson2, Aliyah Pabani3, Nicholas Smith1, Shelly Gray1, Jose Garcia4, Noel Weiss1 and Namrata Singh5, 1University of Washington, Seattle, WA, 2VA Puget Sound Health Care System, Seattle, WA, 3Johns Hopkins, Washington, DC, 4VA Puget Sound Health Care System, VA GRECC, and University of Washington, Seattle, WA, 5University of Washington, Bellevue, WA

    Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of malignancies, particularly lung cancer, relative to the general population1. However, the association between RA…
  • Abstract Number: 2235 • ACR Convergence 2025

    Proportion of Early Rheumatoid Arthritis Patients with Improved, Stable, or Worsened Lung Function Over 1-Year: Results from a Multicenter, Prospective Cohort Study

    Erica Mulcaire-Jones1, Suiyuan Huang1, Xiaosong Wang2, Misti Paudel3, Ying Qi4, Grace Qian5, Liya Sisay Getachew6, Emily Kowalski6, Kevin Mueller5, Alene Saavedra5, Lauren O'Keeffe5, Natalie Davis7, Alison Puri8, Kathleen Vanni5, Caleb Bolden9, Tina Mahajan10, Marzieh Jamali1, Pierre Antoine Juge11, Tracy J. Doyle12, Marcy Bolster13, Kevin Deane14, Raul San Jose Estepar5, George Washko5, Gregory McDermott7, Bryant England10, Jeffrey Sparks6 and Dinesh Khanna1, 1University of Michigan, Ann Arbor, MI, 2Brigham and Women's Hospital, Natick, MA, 3Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, 4Brigham and Women’s Hospital, Boston, 5Brigham and Women's Hospital, Boston, 6Brigham and Women's Hospital, Boston, MA, 7Brigham and Women's Hospital, Brookline, MA, 8Boston University, Brookline, MA, 9Massachusetts General Hospital, Boston, 10University of Nebraska Medical Center, Omaha, NE, 11Hopital Bichat, APHP, Paris, France, 12Brigham and Women's Hospital, West Roxbury, MA, 13Massachusetts General Hospital, Concord, MA, 14University of Colorado Denver Anschutz Medical Campus, Aurora, CO

    Background/Purpose: Several lung diseases are associated with rheumatoid arthritis (RA), including interstitial lung disease (ILD) and emphysema. In RA-ILD baseline lung function and decline in…
  • Abstract Number: 2047 • ACR Convergence 2025

    Trends in Lung Transplant Listing Outcomes in Connective Tissue Disease associated Interstitial Lung Disease (CTD-ILD) Across Two Decades

    Sambhawana Bhandari1, Derek E. Byers1 and Deepali Sen2, 1Washington University in St. Louis School of Medicine, St. Louis, 2Washington University in St Louis, Chesterfield, MO

    Background/Purpose: Lung transplantation represents a potential life-extending therapy for patients with advanced CTD-ILD. This study aims to characterize lung transplant listing outcomes among CTD-ILD patients…
  • Abstract Number: 1927 • ACR Convergence 2025

    Development of the PREVAIL model of care: Optimizing feasibility and acceptability for trial implementation

    Louise Thoma1, Joel Thompson2, Jason Sharpe3, Beth Jonas4, Patti Katz5 and Kelli Allen6, 1University of North Carolina, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Cary, NC, 3Flatiron Health, Durham, NC, 4University of North Carolina at Chapel Hill, Chapel Hill, NC, 5UCSF, San Rafael, CA, 6University of North Carolina, Durham, NC

    Background/Purpose: Exercise guidance and referral to physical therapy are not consistently delivered when appropriate in rheumatology care for adults with rheumatoid arthritis (RA). The PREVAIL…
  • Abstract Number: 1748 • ACR Convergence 2025

    Effect of Air Pollution on Disease Activity in Patients with Rheumatoid Arthritis

    Sung Cheol Jung1, Jeffrey Curtis2, Seojin Yang3, Min Hyuk Lim4, Saram Lee5, Sung Ik Cho6, Jin Kyun Park7 and Eun Bong Lee6, 1Seoul National University College of Medicine, Seoul, Republic of Korea, 2University of Alabama at Birmingham, Birmingham, AL, 3Seoul National University, Seoul, Republic of Korea, 4Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea, 5Seoul National University Hospital, Seoul, Republic of Korea, 6Seoul National University Hospital, Seoul, South Korea, 7Seoul National University College of Medicine, Jongno-gu, Seoul, South Korea

    Background/Purpose: While air pollution has been implicated in the pathogenesis of rheumatoid arthritis (RA), its association with RA disease activity remains insufficiently investigated (1, 2).…
  • Abstract Number: 1675 • ACR Convergence 2025

    Neuroimmune modulation in patients with active rheumatoid arthritis with an inadequate response to TNF inhibitors (TNFi)

    Guillermo Valenzuela1, Jane Box2, Angela Crowley3, Joshua June4, Pendleton Wickersham5, Jeff Peterson6, Michael Thakor7, Susan Kim8, Tina Shah9, David Chernoff10 and John Tesser11, 1Integral Rheumatology & Immunology Specialists, Plantation, FL, 2DJL Clinical Research, PLLC, Charlotte, NC, 3Illinois Bone and Joint Institute - Hinsdale Orthopaedics, Hinsdale, IL, 4Great Lakes Center of Rheumatology, Lansing, MI, 5Arthritis Associates PA, San Antonio, TX, 6Western Washington Arthritis Clinic, Seattle, WA, 7arthritis and rheumatology, Fort Collins, CO, 8Lehigh Valley Hospital Network, Allentown, PA, 9Kansas City Physician Partners, Kansas City, MO, 10SetPoint Medical, Sausalito, CA, 11Arizona Arthritis & Rheumatology Associates, Phoenix, AZ

    Background/Purpose: A substantial number of patients with rheumatoid arthritis (RA) experience treatment failure, incomplete response, or intolerance to TNFis (TNFi-IR). Neuroimmune modulation using an implantable…
  • Abstract Number: 1371 • ACR Convergence 2025

    Effect of bDMARDs and tsDMARDS on diffuse interstitial lung disease associated with rheumatoid arthritis: systematic review and meta-analysis

    Stéphane HILLIQUIN1, Enrico VISMARA1, Virginia BERLENGIERO2 and Jérôme AVOUAC3, 1Département de Rhumatologie, Hôpital Cochin, Assistance publique des Hôpitaux de Paris, Université Paris-Cité, Paris, France, PARIS, France, 2Rheumatoloy Department, Cochin Hospital, PARIS, France, 3Rheumatology department, Cochin hospital, Paris, France

    Background/Purpose: Interstitial lung disease (ILD) is a severe complication of rheumatoid arthritis (RA), associated with increased morbidity and mortality. The pulmonary safety of biologic (bDMARDs)…
  • Abstract Number: 1353 • ACR Convergence 2025

    Phase 3 Study of the Efficacy, Safety and Immunogenicity of the Proposed Tocilizumab Biosimilar RGB-19, Intravenously Administered to Participants With Active Rheumatoid Arthritis: 52-Week Data

    Gerd Burmester1, Hiroaki Matsuno2, Ernest Choy3, Masato Okada4, Roshan Dias5, Károly Horvát-Karajz5, Gordana Dancer5, Yusuke Karibe6, Suguru Masuda6, Joachim Kiefer5 and Paul Emery7, 1Department of Rheumatology and Clinical Immunology, Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Matsuno Clinic for Rheumatic Disease, Toyama, and Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, 3Division of Infection and Immunity, CREATE Centre, Cardiff University, Cardiff, United Kingdom, 4Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, 5Gedeon Richter Plc, Budapest, Hungary, 6Mochida Pharmaceutical Co., Ltd, Tokyo, Japan, 7University of Leeds, Leeds, England, United Kingdom

    Background/Purpose: RGB-19 is a proposed biosimilar to tocilizumab, a monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor. Results of a…
  • Abstract Number: 1336 • ACR Convergence 2025

    Effectiveness of new initiators of tofacitinib and other biologic/targeted synthetic DMARDs in patients with rheumatoid arthritis

    Katherine Liao1, Chandrasekar Gopalakrishnan2, Jinoos Yazdany3, Griffith Bell4, Suraj Mothi5, Genevieve Gauthier6, Arne Yndestad7 and Milena Gianfrancesco8, 1Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital, Boston, MA, USA, Boston, MA, 2OM1 Inc, Boston, MA, USA, Boston, 3UCSF, San Francisco, CA, 4Pfizer Inc, New York, NY, USA, Boston, MA, 5OM1 Inc, Boston, MA, USA, Boston, MA, 6Pfizer Canada ULC, Kirkland, QC, Canada, Montreal, Canada, 7Pfizer Inc, Oslo, Norway, Oslo, Norway, 8Pfizer Inc, New York, NY, USA, New York, NY

    Background/Purpose: Though the efficacy and safety profile of tofacitinib in RA has been established in prior trials, the effectiveness of tofacitinib in routine care settings…
  • Abstract Number: 1319 • ACR Convergence 2025

    The Association of Rheumatoid Arthritis in Patients with Vitiligo: Systematic Review and Meta-Analysis

    Nattanicha Chaisrimaneepan1, thunyaporn Khoruamklang2, Pitchaporn Yingchoncharoen3, Tulaton Sodsri4 and Miriam Paz3, 1Texas Tech University Health Sciences Center, Lubbock, TX, 22Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, bangkok, Thailand, 3Texas Tech University Health Sciences Center, Lubbock, 4Department of Medicine, Texas Tech University Health Sciences Center, Bangkok, Thailand

    Background/Purpose: Vitiligo is associated with many autoimmune diseases, but its association with rheumatic disease has not been well-defined. Therefore, we conducted a systematic review and…
  • Abstract Number: 1266 • ACR Convergence 2025

    Shared Decision Making in Rheumatoid Arthritis: Is RA disease activity associated with patient reported measures of shared decision making pre-SDM intervention?

    Jennifer Barton1, Joshua Baker2, gabriela Schmajuk3, Madhavi Valiveti4, Alexandra Bennett5, Benjamin Morasco6, Allison O'Neill7 and Meike Niederhausen8, 1VA Portland Health Care System/OHSU, Portland, OR, 2University of Pennsylvania, Philadelphia, PA, 3University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA, 4VAMC Wilmington, Wilmington, DE, 5Center to Improve Veteran Involvement in Care (CIVIC) and VA Portland Health Care System, Portland, OR, 6Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR, 7Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR, 8Oregon Health & Science University/VA Portland Health Care System, Portland, OR

    Background/Purpose: Shared decision making (SDM) is outlined as the first overarching principle of the treat to target guidelines for rheumatoid arthritis (RA). The quality of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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