Abstracts tagged "Rheumatoid arthritis (RA)"

Abstract Number: 1524 • 2014 ACR/ARHP Annual Meeting
Rituximab Done! What’s Next in RA?
Ulrich A. Walker¹, Veronika K. Jaeger¹, Katerina Chatzidionysiou², Merete Lund Hetland^3,4, Ellen Margrethe Hauge^3,4, Karel Pavelka⁵, Dan C. Nordström⁶, Helena Canhao⁷, Matija Tomsic⁸, Ronald van Vollenhoven² and Cem Gabay⁹, ¹Department of Rheumatology, University Hospital Basel, Basel, Switzerland, Basel, Switzerland, ²Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, ³Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, ⁴DANBIO, Center for Rheumatology and Spine Diseases, Glostrup University Hospital, Glostrup, Denmark, Glostrup, Denmark, ⁵Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁶ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, Helsinki, Finland, ⁷Rheumatology Research Unit, Instituto de Medicina Molecular, Lisbon, Portugal on behalf of the Rheumatic Diseases Portugal Register, Lisbon, Portugal, ⁸Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, Ljubljana, Slovenia, ⁹University Hospitals of Geneva/SCQM Registry, Geneva, Switzerland, Geneva, Switzerland
Background/Purpose The optimal strategy to use biologics after rituximab (RTX) in RA is unknown. We therefore aimed to evaluate the effectiveness of different biologics after…
Abstract Number: 904 • 2014 ACR/ARHP Annual Meeting
Ultrasound Synovitis Reflects Synovial Inflammation at a Histopathological Level
Nora Ng, Stephen Kelly, Frances Humby, Maria DiCicco, Vidalba Rocher, Rebecca Hands, Michele Bombardieri and Costantino Pitzalis, Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom
Background/Purpose: Ultrasound (US) is widely used by rheumatologists to assess inflammatory burden on patients with inflammatory arthritis. Some studies have shown that US measures of…
Abstract Number: 375 • 2014 ACR/ARHP Annual Meeting
Evaluation of RAPID3 with Minimal Joint Count and ACR/EULAR Provisional Remission Definitions As Predictors of Future Good Radiographic + Functional Outcome in a Double-Blind, Phase 3, Randomized Controlled Trial of Tocilizumab
Martin J. Bergman¹, Jeffrey Yourish², Jinglan Pei², Jenny Devenport², William Reiss² and Edward Keystone³, ¹Taylor Hospital, Ridley Park, PA, ²Genentech, South San Francisco, CA, ³University of Toronto and Mount Sinai Hospital, Toronto, ON, Canada
Background/Purpose: Based on treat-to-target guidelines, the goal of treatment should be remission. Definitions for remission recommended by the ACR/EULAR task force include joint counts and…
Abstract Number: 2426 • 2014 ACR/ARHP Annual Meeting
Comparison of Patient Self-Reported and Physician Reported Rheumatoid Arthritis Medication Use – Results from the Ontario Best Practices Research Initiative
Binu Jacob¹, Xiuying Li¹, Angela Cesta², Bindee Kuriya³, Edward Keystone⁴ and Claire Bombardier³, ¹University Health Network, Toronto General Research Institute, Toronto, ON, Canada, ²Clinical Decision Making and Health Care, University Health Network, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto, ON, Canada, ⁴Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose Patient self-reported medication histories may be prone to misclassification and recall bias. We aimed to assess the agreement between patient (Pt) and physician (MD)…
Abstract Number: 1534 • 2014 ACR/ARHP Annual Meeting
Disease Severity and Treatment of Rheumatoid Arthritis: A Comparative Study Between Sudan and Sweden
Amir Elshafie¹, Abdalla D Elkhalifa², Thomas Weitoft³, Musa Nur⁴, Elnour Elagib⁵, Mawahib Aledrissy⁶, Sahwa Elbagir⁷ and Johan Rönnelid⁸, ¹Immunology, Genetics and Pathology, MD, MDpath, PhD, Uppsala, Sweden, ²Rheumatology unit, MD, Gävle, Sweden, ³Rheumatology unit, MD, PhD, Gävle, Sweden, ⁴Alribat University Hospital, MD, FRCP, Khartoum, Sudan, ⁵Rheumatology unit, Alribat University Hospital, MD, FRCP, Khartoum, Sudan, ⁶Rheumatology unit, Alribat University Hospital, MD, MD internal Medicine, Khartoum, Sudan, ⁷Immunology, Genetics and Pathology, M, PhD student, Uppsala, Sweden, ⁸Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
Background/Purpose: To perform a comparative study concerning clinical characteristics and treatment between Sudanese and Swedish RA outpatients. Methods: A 286 Sudanese and 542 Swedish RA…
Abstract Number: 839 • 2014 ACR/ARHP Annual Meeting
Cardiovascular Risk with Nsaids in Rheumatoid Arthritis: An Analysis Using Routinely Collected Data
Fowzia Ibrahim¹, Antigoni Grigoriou^1,2, Khaldoun Chaabo^1,2, David L. Scott^1,2, Sophia Steer^1,2 and James Galloway^1,2, ¹King's College London, Department of Rheumatology, London, United Kingdom, ²King's College Hospital, Department of Rheumatology, London, London, United Kingdom
Background/Purpose Atherosclerotic disease increases the morbidity and mortality in Rheumatoid Arthritis (RA). NSAIDs are associated with Cardiovascular (CV) risk in the general population. Data from…
Abstract Number: 324 • 2014 ACR/ARHP Annual Meeting
Regulation of TNF-α-Mediated Activation of Rheumatoid Synovial Fibroblasts By Transcription Factor Snail
Chrong-Reen Wang^1,2, Shih-Yao Chen³, Ai-Li Shiau⁴, I-Ming Jou^5,6, Ming-Fei Liu^1,2 and Chao-Liang Wu³, ¹Internal Medicine, National Cheng Kung University Medical College, Tainan, Taiwan, ²Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan, ³Biochemistry and Molecular Biology, National Cheng Kung University Medical College, Tainan, Taiwan, ⁴Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan, ⁵Orthopedics, National Cheng Kung University Medical College, Tainan, Taiwan, ⁶Orthopedics, National Cheng Kung University Hospital, Tainan, Taiwan
Background/Purpose: Transcription factor Snail plays active roles in various biological functions and is involved in many disease states. We hypothesized that this molecule regulates TNF-α-mediated…
Abstract Number: 2431 • 2014 ACR/ARHP Annual Meeting
Tai Chi and Yoga Are Effective for Improving Physical Function in Adults with Rheumatoid Arthritis- a Meta-Analysis
Heather Greysen and Kathy Lee, School of Nursing, University of California San Francisco, San Francisco, CA
Authors: Greysen, H.1., Lee, K.11. School of Nursing, University of California San FranciscoTitle: Tai Chi and Yoga Are Effective for Improving Physical Function in Adults…
Abstract Number: 1511 • 2014 ACR/ARHP Annual Meeting
COVA322: A Clinical Stage Bispecific TNF/IL-17A Inhibitor for the Treatment of Inflammatory Diseases
Wibke Lembke, Bernd Schlereth, Julian Bertschinger, Dragan Grabulovski and Mathias Locher, Covagen AG, Schlieren, Switzerland
Background/Purpose: Biologic therapeutics such as TNF inhibitors have revolutionized the treatment of inflammatory diseases, including rheumatoid arthritis (RA), psoriasis and psoriatic arthritis. However, there is still…
Abstract Number: 592 • 2014 ACR/ARHP Annual Meeting
Clinical and Psychological Correlates of Sleep Difficulties in Patients with Spondyloarthropathies Compared to Patients with Rheumatoid Arthritis
Konstantinos Kotsis¹, Thomas Hyphantis², Paraskevi V. Voulgari³, Andre F. Carvalho⁴ and Alexandros A. Drosos⁵, ¹Department of Psychiatry, Medical School, University of Ioannina, 45110, Ioannina, Greece., Department of Psychiatry, Medical School, University of Ioannina, 45110, Ioannina, Greece., Ioannina, Greece, ²Department of Psychiatry, Medical School, University of Ioannina, Ioannina 45110, Greece., Department of Psychiatry, Medical School, University of Ioannina, Ioannina 45110, Greece., Ioannina, Greece, ³Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, 45110, Associate Professor of Rheumatology, Ioannina, Greece, ⁴Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil., Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil., Fortaleza, Brazil, ⁵Rheumatology Clinic, Department of Internal Medicine, University of Ioannina, Ioannina, Greece
Background/Purpose Sleep difficulties are common in patients with rheumatological disorders. Patients with Rheumatoid Arthritis (RA) report frequently poor quality sleep, numerous night awakening and difficulty…
Abstract Number: 133 • 2014 ACR/ARHP Annual Meeting
On-Demand Ultrasonography Assessment in the Most Affected Joint Is Efficient for Management of RA Patients in Daily Practice
Ryusuke Yoshimi¹, Takeno Mitsuhiro², Yukihiro Toyota¹, Naomi Tsuchida¹, Yumiko Sugiyama¹, Yosuke Kunishita¹, Daiga Kishimoto¹, Reikou Kamiyama¹, Kaoru Minegishi-Takase¹, Maasa Hama³, Yohei Kirino¹, Atsuhisa Ueda¹ and Yoshiaki Ishigatsubo¹, ¹Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ²Clinical Laboratory Department, Yokohama City University Hospital, Yokohama, Japan, ³Yokohama City University Graduate School of Medicine, Yokohama, Japan
Background/Purpose: Musculoskeletal ultrasonography (US) is recognized as a useful tool for the diagnosis and monitoring of rheumatoid arthritis (RA). Although several sets of power Doppler…
Abstract Number: 2377 • 2014 ACR/ARHP Annual Meeting
A Pilot Randomized Controlled Trial of a Tailored Smoking Cessation Intervention for Rheumatoid Arthritis Patients
Pip Aimer¹, Gareth Treharne², Simon Stebbings³, Christopher Frampton⁴, Vicky Cameron¹, Sandra Kirby⁵ and Lisa K. Stamp⁴, ¹Medicine, University of Otago, Christchurch, Christchurch, New Zealand, ²Psychology, University of Otago, Dunedin, New Zealand, ³Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, ⁴Department of Medicine, University of Otago, Christchurch, Christchurch, New Zealand, ⁵Arthritis New Zealand, Wellington, New Zealand
Background/Purpose Smoking adversely influences comorbidities in rheumatoid arthritis (RA) and may affect progression of RA. The combination of negative health effects makes a compelling case…
Abstract Number: 1483 • 2014 ACR/ARHP Annual Meeting
Efficacy and Safety of Baricitinib in Japanese Rheumatoid Arthritis Patients during a 52 Week Extension Phase
Yoshiya Tanaka¹, Kahaku Emoto², Zhihong Cai², Douglas E. Schlichting³, Terence Rooney³ and William Macias³, ¹University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, ²Eli Lilly Japan K.K., Kobe, Japan, ³Eli Lilly and Company, Indianapolis, IN
Background/Purpose Baricitinib (bari), an oral JAK1/JAK2 signaling inhibitor, was evaluated in a blinded phase 2b study for 12 weeks as a treatment for rheumatoid arthritis…
Abstract Number: 504 • 2014 ACR/ARHP Annual Meeting
Abatacept after Rituximab in Rheumatoid Arthritis. a Pan-European Collaboration of RA Registries
Axel Finckh¹, David Neto², M. Victoria Hernández³, Florenzo Iannone⁴, Elisabeth Lie⁵, Helena Canhao⁶, K Pavelka⁷, Carl Turesson⁸, Xavier Mariette⁹, Merete Lund Hetland¹⁰ and Jacques Gottenberg¹¹, ¹Rheumatology, Geneva University Hospital, Geneva, Switzerland, ²University of Geneva, Geneva, Switzerland, ³Arthritis Unit. Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, ⁴Reumatologia Universita e Policlinico di Bari, Bari, Italy, ⁵Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ⁶Rheumatology Research Unit, Instituto de Medicina Molecular, Universidade de Lisboa, Lisbon, Portugal, ⁷Institute of Rheumatology, Prague, Czech Republic, ⁸Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ⁹rheumatology, Université Paris-Sud, Le Kremlin Bicêtre, France, ¹⁰DANBIO, Center for Rheumatology and Spine Diseases, Glostrup Univ Hospital, Glostrup, Denmark, ¹¹Rheumatology, Strasbourg University Hospital, Strasbourg, France
Background/Purpose Some observations have suggested that the effectiveness of abatacept (ABA) may be decreased in rheumatoid arthritis (RA) patients (pts) who previously failed rituximab (RTX).(1)…
Abstract Number: 131 • 2014 ACR/ARHP Annual Meeting
Detection of Synovitis and Erosions with an Automated Ultrasound System: Data from a Prospective Cohort with Early and Established RA
Matthias Witt¹, Janette Frielinghausen², Jan Leipe², Hendrik Schulze-Koops², Ruediger Mueller³ and Mathias Grunke², ¹Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany, ²Division for Rheumatology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany, ³Rheumatology, Kantonspital St. Gallen, St. Gallen, Switzerland
Background/Purpose: Arthrosonography has proven to be a sensitive and reliable, but time-consuming method for the evaluation of arthritis in small joints of patients with RA…

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