Abstracts tagged "Rheumatoid arthritis (RA)"

Abstract Number: 2490 • 2017 ACR/ARHP Annual Meeting
Sustained Clinical Response in Refractory Rheumatoid Arthritis Patients with a Low-Dose Rituximab Retreatment Regimen. a Single Center Experience
Sebastian C Rodriguez-Garcia, Raul Castellanos-Moreira Sr., M. Victoria Hernández, Andrea Cuervo, Virginia Ruiz-Esquide, Julio Ramírez, Juan Cañete and Raimon Sanmartí, Rheumatology Service, Hospital Clínic de Barcelona, Barcelona, Spain
Background/Purpose: : The standard dose of rituximab (RTX) in rheumatoid arthritis (RA) is two intravenous (iv) 1 g infusions, separated by two weeks. Recently, the…
Abstract Number: 411 • 2017 ACR/ARHP Annual Meeting
Factors That Drive Treatment Recommendation during Rheumatoid Arthritis Patient´s Follow-up, Differ According to Physician Experience
César Sifuentes-Cantú¹, Irazu Contreras-Yañez², Lina Saldarriaga Rivera³, Ana Cecilia Lozada⁴, Marwin Gutierrez⁵ and Virginia Pascual-Ramos¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ³Instituto Nacional de Rehabilitación, Mexico, Mexico, ⁴Division of musculoskeletal and rheumatic diseases, Instituto Nacional de Rehabilitación, Mexico City, Mexico, ⁵Rheumatology, Instituto Nacional de Rehabilitación, Mexico City, Mexico
Background/Purpose: The management plan for rheumatoid arthritis (RA) might be a relatively simple task if only disease activity is considered but might become more complex…
Abstract Number: 848 • 2017 ACR/ARHP Annual Meeting
“Suddenly You Are a Person at Risk of Developing Rheumatoid Arthritis!” Different Perspectives of Individuals on Predictive Testing – Results of an International Qualitative Interview Study
Erika Mosor¹, Michaela Stoffer², Günter Steiner³, Karim Raza⁴, Rebecca J Stack⁴, Gwenda Simons⁴, Marie Falahee⁴, Georg Schett⁵, Matthias Englbrecht⁶, Josef S. Smolen², Axel J. Hueber⁶ and Tanja Stamm⁷, ¹Section for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria, 1090 Vienna, Austria, ²Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, Vienna, Austria, ³Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Department of Rheumatology, University of Birmingham and Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK, Birmingham, United Kingdom, ⁵Rheumatology and Immunology, Department of Internal Medicine 3, Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, ⁶Department of Medicine 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁷Section for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Vienna, Austria
Background/Purpose: People at risk of developing rheumatoid arthritis (RA) may be candidates for interventions aimed at preventing RA development [1]. The identification of such at…
Abstract Number: 2008 • 2017 ACR/ARHP Annual Meeting
“Intrathoracic Manifestations of Connective Tissue Diseases on High Resolution Computed Tomography”
Diego Baenas¹, Maira Orozco², María Eugenia Olmos³, Luis Lasca⁴, Paula Riba⁵, Patricio Muszinsky⁵, Juan Pablo Pirola⁶, Verónica Saurit⁷, Alejandro Alvarellos⁷, Ana C. Alvarez⁸, Soledad Retamozo^9,10, Nadia Riscanevo^7,11, Janet Flores¹², Ariel Blua³, Ana María López¹³, Gustavo Muiño¹⁴, Santiago Orozco¹⁵ and Francisco Caeiro¹⁶, ¹Rheumatology Unit, Hospital Privado Universitario de Córdoba, Postgraduate Career of Rheumatology Catholic University of Córdoba., Cordoba, Argentina, ²Radiology, Radiology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ³Pulmonary, Pulmonary Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ⁴Radiology Unit, Oulton Institute, Cordoba, Argentina, ⁵Radiology, Radiology Unit, Oulton Institute, Cordoba, Argentina, ⁶Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba., Cordoba, Argentina, ⁷Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ⁸Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, ⁹Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas (INICSA-UNC-CONICET), Cordoba, Argentina, ¹⁰Hospital Privado Centro Médico de Córdoba, Cordoba, Argentina, ¹¹Rheumatology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ¹²Rheumatology Unit, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ¹³Pulmonary Unit, Pulmonary Unit, Hospital Privado Universitario de Córdoba., Cordoba, Argentina, ¹⁴Radiology, Radiology Unit,Hospital Privado Universitario de Córdoba., Cordoba, Argentina, ¹⁵Radiology, Radiology Unit, Hospital Privado Universitario de Córdoba., Cordoba, Argentina, ¹⁶Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina
Background/Purpose: Connective tissue diseases (CTD) can cause intrathoracic involvement, increasing patients morbidity and mortality. High-resolution computed tomography (HRCT) is a key method for evaluation of…
Abstract Number: 2795 • 2017 ACR/ARHP Annual Meeting
Comparison of Switching from the Originator Rituximab to the Biosimilar Rituximab GP2013 or Re‑Treatment with the Originator Rituximab in Patients with Active Rheumatoid Arthritis: Safety and Immunogenicity Results from a Multicenter, Randomized, Double-Blind Study
Hans-Peter Tony¹, Hendrik Schulze-Koops², Klaus Krüger³, Stanley B Cohen⁴, Alan J. Kivitz⁵, Slawomir Jeka⁶, Edit Vereckei⁷, Liyi Cen⁸ and Dmitrij Kollins⁸, ¹Department of Internal Medicine 2, Rheumatology and Clinical Immunology, University Hospital Würzburg, Würzburg, Germany, ²Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, University of Munich, Munich, Germany, ³Praxiszentrum St. Bonifatius München, München, Germany, ⁴Metroplex Clinical Research Centre, Dallas, TX, ⁵Altoona Center for Clinical Research, Duncansville, PA, ⁶2nd University Hospital, CM UMK, Department of Rheumatology and Connective Tissue Diseases,, Bydgoszcz, Poland, ⁷National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, ⁸Clinical Development, Sandoz, a Novartis Division, Holzkirchen, Germany
Background/Purpose: GP2013, is a biosimilar to European Union (EU) approved reference rituximab (RTX), developed in a stepwise approach that adheres to stringent biosimilar development guidelines.…
Abstract Number: 135 • 2016 ACR/ARHP Annual Meeting
The 8-Joint Ultrasound Score Is a Useful Marker for Monitoring Therapeutic Response in Rheumatoid Arthritis
Ryusuke Yoshimi¹, Yukihiro Toyota¹, Naomi Tsuchida¹, Yumiko Sugiyama¹, Yosuke Kunishita¹, Daiga Kishimoto¹, Reikou Kamiyama¹, Kaoru Minegishi², Maasa Tamura¹, Yukiko Asami¹, Yohei Kirino¹, Shigeru Ohno² and Hideaki Nakajima¹, ¹Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan, ²Center for Rheumatic Disease, Yokohama City University Medical Center, Yokohama, Japan
Background/Purpose: Musculoskeletal ultrasonography (US) is one of the standard tools for the diagnosis and monitoring of rheumatoid arthritis (RA). Although we and other groups have…
Abstract Number: 1114 • 2016 ACR/ARHP Annual Meeting
Extracellular Vesicles in the Circulating of Rheumatoid Arthritis Patients Are Pro-Inflammatory
Onno J. Arntz¹, Bartijn C.H. Pieters¹, Rogier Thurlings², Peter L. E. M. van Lent³, Peter M. van der Kraan³, Marije I. Koenders¹, FHJ van den Hoogen² and Fons A.J. van de Loo¹, ¹Experimental Rheumatology, Radboudumc, Nijmegen, Netherlands, ²Rheumatology, Radboudumc, Nijmegen, Netherlands, ³Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is a progressive and degenerative joint disease with chronic synovial inflammation in multiple joints. Interestingly, the symmetry and spreading of the…
Abstract Number: 1973 • 2016 ACR/ARHP Annual Meeting
Intramuscular Versus Ultrasound Guided Peritendinous Glucocorticoid Injection for Tenosynovitis in Patients with Rheumatoid Arthritis – a Randomised, Double-Blind, Controlled Study
Mads Ammitzbøll-Danielsen^1,2, Mikkel Ostergaard^2,3, Viktoria Fana⁴, Daniel Glinatsi^2,5, Uffe Møller Døhn⁶, Lykke Midtbøll Ørnbjerg⁷, Esperanza Naredo⁸ and Lene Terslev⁶, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, ²Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, ³Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Center for Rheumatology and Spine Diseases, Rigshospitalet , Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, ⁵Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ⁶Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, ⁷Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ⁸Rheumatology, Hospital General Universitario Gregorio Marañón and Universidad Complutense, Madrid, Spain
Background/Purpose: The aim of this study was to compare the efficacy of intramuscular versus ultrasound (US)-guided peritendinous glucocorticoid injection in providing disease control after…
Abstract Number: 2604 • 2016 ACR/ARHP Annual Meeting
Ultrasound and Immunological Changes and Associations after One Year of IL-6/IL- 6R Blockade with Tocilizumab in Rheumatoid Arthritis Patients
Cesar Diaz-Torne¹, Juan Jose De Agustin², Patricia Moya¹, Maria A. Ortiz³, Delia Reina⁴, Carme Moragues⁵, Sergi Ros⁶, Emili Gomez⁷, Enrique Casado Burgos⁸, Eli Garcia⁹, Manel Pujol¹⁰, Maria Pilar Lisbona Perez¹¹, Andrés Ponce¹², V Torrente¹³, P. Estrada¹⁴, Silvia Vidal³ and ECOCAT group, ¹Rheumatology, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain, ²Rheumatology, Hospital Baix de Llobregat, Barcelona, Spain, ³Institut de Recerca Sant Pau, Barcelona, Spain, ⁴Rheumatology, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain, ⁵Rheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ⁶Rheumatology, Hospital de Viladecans, Viladecans, Spain, ⁷Rheumatology, Hospital Clínic, Barcelona, Spain, ⁸Hospital Universitari Parc Taulí, Sabadell, Spain, ⁹Rheumatology, Hospital de Mollet, Mollet, Spain, ¹⁰Hospital Mútua de Terrassa, Terrassa, Spain, ¹¹Rheumatology, Hospital de Sabadell, Sabadell, Spain, ¹²Rheumatology. Internal Medicine, Hospital General de Granollers, Granollers, Spain, ¹³Hospital de L'Hospitalet, L'Hospitalet de Llobregat, Spain, ¹⁴Rheumatology, Hospital Moises Broggi, Barcelona, Spain
Background/Purpose: Management of RA patients has improved in the last two decades in part with the use of ultrasound (US) in daily clinical practice. The…
Abstract Number: 136 • 2016 ACR/ARHP Annual Meeting
The 7-Joints Musculoskeletal Ultrasound Score (US7 score) Predicts Therapeutic Change in Patients with Early Rheumatoid Arthritis
Sarah Ohrndorf¹, Philipp Daniel Oberdorfer², Lien Le³, Ulrich Mansmann³, Lisa Ines Sprenger², Thomas Häupl⁴, Sandra Hermann², Gabriela Schmittat², Silvia Pade², GR Burmester⁵, Anne-Marie Glimm² and Marina Backhaus⁶, ¹Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany, ³Institut für medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität Munich, Munich, Germany, ⁴Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ⁵Charité – University Medicine Berlin, Berlin, Germany, ⁶Department of Rheumatology & Immunology, University Medicine Charit, Berlin, Germany
Background/Purpose: Treatment decisions in patients with Rheumatoid Arthritis (RA) after the “Treat to Target (T2T)” - principle is widely recommended, as this management strategy leads…
Abstract Number: 1117 • 2016 ACR/ARHP Annual Meeting
EGCG Down-Regulates TNF-α-Induced Mcl-1 Expression By Modulating Mule/Huwe1, β-TrCP, and USP9X Ubiquitin/De-Ubiquitin Ligases in Rheumatoid Arthritis Synovial Fibroblasts
Nahid Akhtar¹, Sadiq Umar², David Fox³ and Salahuddin Ahmed¹, ¹Department of Pharmaceutical Sciences, Washington State University, College of Pharmacy, Spokane, WA, ²Department of Pharmaceutical Science, Washington State University, College of Pharmacy, Spokane, WA, ³Department of Medicine [Division of Rheumatology], University of Michigan, Ann Arbor, MI
Background/Purpose: Myeloid cell leukemia (Mcl-1) phosphorylation at Ser64 position (p-Mcl-1Ser64) has been shown to enhance Mcl-1’s stability and resistance to proteasomal degradation. However, the…
Abstract Number: 1975 • 2016 ACR/ARHP Annual Meeting
Severity and Improvement of Morning Stiffness Independently Associate with Tenosynovitis in Patients with Rheumatoid Arthritis
Yoshihisa Kobayashi^1,2,3, Kei Ikeda¹, Takayuki Nakamura^1,4, Mieko Yamagata^1,5, Takuya Nakazawa^1,6, Shigeru Tanaka¹, Shunsuke Furuta¹, Takeshi Umibe³ and Hiroshi Nakajima¹, ¹Chiba University Hospital, Chiba, Japan, ²Chiba Aoba Municipal Hospital, Chiba, Japan, ³Matudo City Hospital, Matudo, Japan, ⁴Asahi General Hospital, Asahi, Japan, ⁵National Hospital Organization Shimoshizu National Hospital, Yotsukaido, Japan, ⁶National Hospital Organization Chiba-East Hospital, Chiba, Japan
Background/Purpose: Morning stiffness has long been recognized by both patients and rheumatologists as a characteristic feature of rheumatoid arthritis (RA). However, morning stiffness is no…
Abstract Number: 2609 • 2016 ACR/ARHP Annual Meeting
The Effectiveness of Zoster Vaccine in RA Patients Subsequently Treated up to 19 Months with Tofacitinib
Kevin L Winthrop¹, Ann Wouters², Ernest H. Choy^3,4, Chudy Nduaka², Staci Abramsky², Pinaki Biswas², Lisy Wang⁵, Jennifer Hodge², Irina Lazariciu⁶, Koshika Soma², Christopher F Mojcik² and William F.C Rigby⁷, ¹Oregon Health and Sciences University, Portland, OR, ²Pfizer Inc, New York, NY, ³CREATE Center, Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, Great Britain, ⁴CREATE Center, Division of Infection and Immunity,, Cardiff University, Cardiff, United Kingdom, ⁵Pfizer Inc, Groton, CT, ⁶Quintiles, Saint-Laurent, QC, Canada, ⁷Geisel School of Medicine at Dartmouth, Lebanon, NH
Background/Purpose: Rheumatoid arthritis (RA) patients are at increased risk for herpes zoster (HZ), and vaccination is recommended in patients over the age of 50 years,…
Abstract Number: 144 • 2016 ACR/ARHP Annual Meeting
Safety, Tolerability and Feasibility of Minimally Invasive Ultrasound-Guided Synovial Biopsyof Wrist and Metacarpophalangeal Joints – an Ultrasound Follow-up Study
Laurent Meric de Bellefon¹, Patrick Durez², Christine Galant³, Adrien Nzeusseu Toukap⁴, Aleksandra Avramovska⁵, Bernard R. Lauwerys⁶, Frédéric A. Houssiau⁷ and Maria S. Stoenoiu⁸, ¹Rheumatology, Cliniques Universitaires Saint-Luc, CHU Saint-Pierre Brussels, Clinique Notre-Dame de Grâce, Gosselies, Brussels, Belgium, ²Rheumatology, Univ Catholique de Louvain, Brussels, Belgium, ³Pôle de pathologies rhumatismales inflammatoires et systémiques, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium, ⁴Department of Rheumatology, Cliniques Universitaires St Luc, Brussels, Belgium, ⁵Rheumatology, Cliniques Universitaires Saint-Luc, Brussels, Belgium, ⁶Department of Rheumatology, Université catholique de Louvain, Brussels, Belgium, ⁷Rheumatology, Pôle de Maladies Rhumatismales, Université catholique de Louvain, Brussels, Belgium, ⁸Service de Rhumatologie, Cliniques Universitaires Saint-Luc,Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain,, Brussels, Belgium
Background/Purpose: The development of ultrasound-guided synovial biopsy will enable synovial tissue collection from small joints and will facilitate molecular studies, thus improving the understanding…
Abstract Number: 1462 • 2016 ACR/ARHP Annual Meeting
Magnesium Is a New Mediator Arthritis Severity and Joint Damage
Teresina Laragione, Nasim Azizgolshani, Carolyn Harris, Erjing Gao and Percio Gulko, Medicine/Rheumatology, Icahn School of Medicine at Mount Sinai, New York, NY
Background/Purpose: Given the effects of magnesium supplementation in suppressing components of the innate immunity in short-term studies, we examined the effect of dietary magnesium modifications…

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