Abstracts tagged "Rheumatoid arthritis (RA)"

Abstract Number: 1421 • 2019 ACR/ARP Annual Meeting
Effect of Tocilizumab on HDL and LDL Characteristics in Patients with Rheumatoid Arthritis: Preliminary Results
Florencia Pierini¹, Ignacio Gandino ¹, Eliana Botta ², Fernando Brites ², Tomas Meroño ², Osvaldo Luis Cerda ³, Gustavo Citera ⁴, Javier Rosa ⁵, Patricia Sorroche ⁶, Laura Boero ², Maximiliano Martin ², Soledad saez ⁶, Walter Tetzlaff ² and Enrique Soriano ⁷, ¹Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina., Capital Federal, Argentina, ²Universidad de Buenos Aires, Buenos Aires, Argentina, ³Instituto de Rehabilitación Psicofísica, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁴Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina, Buenos Aires, Argentina, ⁶Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina., Buenos Aires, Buenos Aires, Argentina
Background/Purpose: In patients with Rheumatoid Arthritis (RA), qualitative alterations of low and high density lipoproteins (LDL and HDL, respectively) might partially explain their increased cardiovascular…
Abstract Number: 1805 • 2019 ACR/ARP Annual Meeting
Perioperative Anti-rheumatic Medications Are Not Associated with 30-day Odds of Infection in Rheumatoid Arthritis Patients Undergoing Surgery: A Retrospective Cohort Study
Marianne Kerski¹, Peter Boersma ², Eric Miller ³, Ashley Brenner ⁴, Genevieve Melton ⁵ and Anna Shmagel ⁶, ¹University of Minnesota Medical School, Minneapolis, MN, ²University of Minnesota School of Public Health, Minneapolis, ³University of Minnesota, Woodbury, MN, ⁴University of Minnesota Best Practices Integrated Informatics Core (BPIC), Minneapolis, MN, ⁵University of Minnesota Department of Surgery, Minneapolis, MN, ⁶University of Minnesota, Minneapolis, MN
Background/Purpose: Perioperative management of anti-rheumatic drugs in rheumatoid arthritis (RA) patients undergoing surgery remains controversial. Previous studies produced conflicting results, and data on non-orthopedic surgeries…
Abstract Number: 1938 • 2019 ACR/ARP Annual Meeting
The Pre-pregnancy Rheumatoid Arthritis Gene Expression Signature Correlates with Improvement or Worsening of Disease Activity During Pregnancy: A Pilot Study
Amogh Pathi ¹, Mette Smed ², Lior Pachter ³, Elizabeth Purdom ⁴, Matthew Wright ⁵, Nicholas Jewell ⁴, J. Lee Nelson ⁶, Jørn Olsen ⁷, Merete Lund Hetland ⁸, Vibeke Zoffmann ⁹ and Damini Jawaheer¹⁰, ¹UCSF Benioff Children's Hospital Oakland, Oakland, ²Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, ³Caltech, Pasadena, ⁴University of California Berkeley, Berkeley, ⁵UCSF Benioff Children's Hopsital Oakland, Oakland, ⁶Fred Hutchinson Cancer Research Center, Seattle, ⁷Aarhus University Hospital, Aarhus, Denmark, ⁸DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ⁹Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, ¹⁰UCSF Benioff Children's Hospital Oakland, Oakland, CA
Background/Purpose: Pregnancy is known to induce a natural improvement of Rheumatoid Arthritis (RA) symptoms in 50-75% of patients as gestation progresses. However, the underlying mechanisms…
Abstract Number: 2091 • 2019 ACR/ARP Annual Meeting
The High Dose Influenza Vaccine Increases Immune Protection in Both Adults and Elderly Seropositive RA Patients
Mariana Useche ¹, Ramanakumar Agnihotram ¹, Sasha Bernatsky ², Brian Ward ³ and Ines Colmegna³, ¹The Research Institute of the McGill University Health Center, Montreal, QC, Canada, ²Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³McGill University Health Center, Montreal, QC, Canada
Background/Purpose: The high dose trivalent inactivated influenza vaccine (HD-TIV) contains four times the antigen dose per strain of the standard-dose inactivated influenza vaccines. HD-TIV is…
Abstract Number: 2258 • 2019 ACR/ARP Annual Meeting
Causes of Influenza Vaccine Hesitancy in Rheumatoid Arthritis and Adults with Juvenile Idiopathic Arthritis
Sandra Pelaez ¹, Vincent Gosselin Boucher ², Valeria Valerio ³, Elizabeth M. Hazel ⁴, Kim Lavoie ⁵, Brian Ward ⁶ and Ines Colmegna⁶, ¹Research Centre of the Sainte-Justine University Hospital, Montreal, Canada, ²Montreal Behavioural Medicine Centre, Centre Intégré Universitaire de santé et services sociaux du Nord-de-l’Ile-de-Montréal (CIUSSS-NIM), Hôpital du Sacré-Cœur de Montréal & Department of Psychology, Université du Québec à Montréal, Montreal, QC, Canada, ³The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁴McGill University Health Centre, Montreal, Canada, ⁵Montreal Behavioural Medicine Centre, Centre Intégré Universitaire de santé et services sociaux du Nord-de-l’Ile-de-Montréal (CIUSSS-NIM), Hôpital du Sacré-Cœur de Montréal & Department of Psychology, Université du Québec à Montréal, Montreal, Canada, ⁶McGill University Health Center, Montreal, QC, Canada
Background/Purpose: Vaccine hesitancy -the reluctance or refusal to vaccinate despite the availability of vaccines- is one of the threats to global health set by the…
Abstract Number: 2314 • 2019 ACR/ARP Annual Meeting
Improved Anxiety, Depression, and Emotional Distress for Rheumatoid Arthritis Patients Following the Completion of an Online Mental Health Intervention
Caitlin Blaney¹, Carol Hitchon ¹, Ruth Ann Marrie ², Corey Mackenzie ¹, Pamela Holens ¹ and Renée El-Gabalawy ², ¹University of Manitoba, Winnipeg, Canada, ²University of Manitoba, Winnipeg, MB, Canada
Background/Purpose: Background: Anxiety and depression are common in people with rheumatoid arthritis (RA). These comorbidities are associated with worse disease outcomes including pain and functional…
Abstract Number: 2332 • 2019 ACR/ARP Annual Meeting
Cardiovascular Risk Factors in Rheumatoid Arthritis: Prevalence, Comparison of Risk Calculators and Subclinical Atherosclerosis in Indian Patients
Hafis Muhammed¹, Durga P Misra ¹, Sujata Ganguly ¹, Sarit Sekhar Pattanaik ¹, Saurabh Chaturvedi ¹, Harshit Singh ¹, Mohit K Rai ¹, Anamika Anuja ¹, Namita Mohindra ¹, Neeraj Jain ¹, Sudeep Kumar ¹ and Vikas Agarwal ¹, ¹SGPGI, Lucknow, Uttar Pradesh, India
Background/Purpose: Rheumatoid arthritis(RA) patients have increased cardiovascular(CV) risk with no data on CV risk scores in Indian patients.The primary objective was to study prevalence of…
Abstract Number: 2356 • 2019 ACR/ARP Annual Meeting
Antirheumatic Therapy Is Not Associated with Changes in Circulating N-terminal Pro-brain Natriuretic Peptide Levels in Patients with Active Rheumatoid Arthritis
Thao Nguyen¹, Gia Deyab ², Morten Fagerland ³, Stefan Agewall ³, Gro Eilertsen ⁴, Mark Feinberg ⁵, Knut Mikkelsen ⁶, Øystein Førre ³ and Ivana Hollan ⁷, ¹Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ²Innlandet Hospital Trust, Bærum, Akershus, Norway, ³Oslo University Hospital, Oslo, Norway, ⁴The Artic University of Norway, Tromsø, Norway, ⁵Harvard Medical School and Brigham and Women´s Hospital, Boston, Boston, MA, ⁶Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Oppland, Norway, ⁷Lillehammer Hospital for Rheumatic Diseases and Brigham and Women’s Hospital, Boston, Lillehammer, Oppland, Norway
Background/Purpose: Patients with rheumatoid arthritis (RA) are predisposed to impaired cardiac function and heart failure (HF). While the pathophysiology has not been fully elucidated yet,…
Abstract Number: 2379 • 2019 ACR/ARP Annual Meeting
High Initial Methotrexate Dose Is Not Associated with an Increased Risk of Liver Toxicity in Korean Patients with Rheumatoid Arthritis
Se Rim Choi¹, Yeong-Wook Song ², Eun Bong Lee ³ and Jin Kyun Park ¹, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Seoul, Republic of Korea, ²Seoul National University Hospital, Seoul, Republic of Korea, ³Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, seoul
Background/Purpose: Methotrexate (MTX) is the most commonly prescribed disease modifying anti-rheumatic drugs (DMARDs) for the treatment of RA due to its high efficacy and favorable…
Abstract Number: 2460 • 2019 ACR/ARP Annual Meeting
Frailty in Ankylosing Spondylitis, Psoriatic Arthritis, and Rheumatoid Arthritis: Data from a National Claims Database
Sarah Lieber¹, Mangala Rajan ², Sebastian E. Sattui ¹, Geyanne Lui ³, Sergio Schwartzman ⁴, Lisa Mandl ⁴ and Iris Navarro-Millan ², ¹Hospital for Special Surgery, New York, ²Weill Cornell Medicine, New York, ³Weill-Cornell Medicine, New York, NY, ⁴Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY
Background/Purpose: Frailty, a state of decreased homeostatic reserve, is associated with increased disability and mortality, independent of age. Frailty has been evaluated in large datasets…
Abstract Number: 2850 • 2019 ACR/ARP Annual Meeting
Exploring Heterogeneity in Rheumatoid Arthritis: Outcomes up to 4 Years of Follow-Up in Patient Clusters Identified by Data-driven Analysis of the BRASS Registry
Jeffrey Curtis¹, Michael Weinblatt ², Kenneth Saag ¹, Vivian Bykerk ³, Christina Charles-Schoeman ⁴, Stefano Fiore ⁵, Gregory St John ⁶, Toshio Kimura ⁷, Shen Zheng ⁵, Clifton Bingham ⁸, Grace Wright ⁹, Martin Bergman ¹⁰, Kamala Nola ¹¹, Daniel Furst ⁴ and Nancy Shadick ², ¹University of Alabama at Birmingham, Birmingham, AL, ²Brigham and Women's Hospital, Boston, MA, ³Hospital for Special Surgery, New York City, NY, ⁴University of California, Los Angeles, CA, ⁵Sanofi Genzyme, Bridgewater, NJ, ⁶Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ⁷Regeneron Pharmaceuticals, Inc, Tarrytown, NY, ⁸Johns Hopkins University, Baltimore, MD, ⁹Private Practice, New York City, NY, ¹⁰Drexel University College of Medicine, Stockholm, Sweden, ¹¹Lipscomb University College of Pharmacy & Health Sciences, Nashville, TN
Background/Purpose: Patients with rheumatoid arthritis (RA) may share characteristics that relate to their future outcomes. We investigated clinical outcomes over a 4-year follow-up period in…
Abstract Number: 7 • 2019 ACR/ARP Annual Meeting
Citrullination of Interleukin 6 Augments Its Pro-inflammatory Capacity and Signaling Potency Through Interleukin-6 Receptor in Rheumatoid Arthritis
Chenyang Lu ¹, Ray Ohara ², Phillip Campbell ¹, Yuxuan Du ³, Alexander Stinson ², Jonatan Hervoso ³, Ellen Cealey ³, David Fox ⁴ and M Amin⁵, ¹the University of Michigan, Ann Arbor, MI, ²Washington University, St. Louis, MO, ³the University of Michigan, Ann Arbor, ⁴University of Michigan, Ann Arbor, ⁵University of Michigan, Ann Arbor, MI
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disorder featured by synovial hyperplasia, inflammatory cell infiltration and presence of anti-citrullinated peptide antibodies (ACPAs) in sera.…
Abstract Number: 58 • 2019 ACR/ARP Annual Meeting
In Rheumatoid Arthritis (RA) Decreases in Conventional Dendritic Cell Lineages Are Associated with Adverse Measures of Myocardial Function and Expansions of Anomalous HLA-DR+ Myeloid Subsets
Christian Geier¹, Jon Giles ², Gilad Gibor ³, Joan Bathon ² and Robert Winchester ³, ¹Columbia University, New York, NY, ²Division of Rheumatology, Columbia University, New York, NY, ³Columbia University, New York
Background/Purpose: Dendritic cells (DC) are specialized antigen-presenting cells (APC) that have a central role in the initiation of immune responses. However, prior studies showed numeric decreases…
Abstract Number: 189 • 2019 ACR/ARP Annual Meeting
Validation of Claims-based Algorithms to Identify Interstitial Lung Disease in Patients with Rheumatoid Arthritis
Soo-Kyung Cho¹, Tracy J. Doyle ², Hemin Lee ³, Yinzhu Jin ³, Angela Y. Tong ³, Adrian J. Santiago Ortiz ³, Jeffrey Sparks ⁴ and Seoyoung C. Kim ³, ¹Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ²Brigham and Women's Hospital, Harvard Medical School, Boston, ³Brigham and Women’s Hospital and Harvard Medical School, Boston, ⁴Brigham and Women's Hospital, Boston, MA
Background/Purpose: The prevalence of interstitial lung disease (ILD) among rheumatoid arthritis (RA) patient ranges between 5-10%. ILD leads to high morbidity and mortality in patients…
Abstract Number: 280 • 2019 ACR/ARP Annual Meeting
Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial
Ulf Sundin¹, Anna-Birgitte Aga ², Øivind Skare ³, Lena Nordberg ³, Till Uhlig ⁴, Hilde Hammer ³, Désirée van der Heijde ⁵, Tore Kvien ⁴, Siri Lillegraven ⁶ and Espen Haavardsholm ⁴, ¹Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway. University of Oslo, Oslo, Norway, Oslo, Oslo, Norway, ²Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Oslo, Norway, ³Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway, ⁴Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway, ⁵Leiden University Medical Center, Leiden, Netherlands, ⁶Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway
Background/Purpose: It has been debated whether treatment outcomes in early RA would be improved by targeting imaging remission, assessed by ultrasound or MRI, in addition…

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